Abstract: The present invention found that, for example, inhibiting phosphorylation of a Ser residue in Regnase-1 is effective in treating and/or preventing diseases. The invention also found that, for example, inhibiting the binding of Regnase-1 with at least one factor selected from the group consisting of TBK1, IKKi, Act-1, IKK, and IRAK is effective in treating and/or preventing diseases.

Abstract: A road surface abnormality detection apparatus includes a data acquisition unit, a prediction unit, and an abnormality detection unit. The data acquisition unit acquires road surface observation data obtained by observing a road surface in a chronological order. The prediction unit predicts road surface data at a first timing from a plurality of road surface observation data at a plurality of respective timings earlier than the first timing by using a trained model generated in advance through machine learning. The abnormality detection unit detects, when a difference between road surface observation data at the first timing and the predicted road surface data at the first timing is equal to or larger than a predetermined threshold, an abnormality of the road surface.

Abstract: An automatic charging system includes: a vehicle driven by power; a charger having a charging cable having a charging connector; a position information acquisition device for obtaining position information of a charging port of the vehicle; a charging robot having a robot arm; and a detection device, which detects an operation of the charging port displaced in a vertical direction. Further, the charging robot insert the charging connector into the charging port based on the position information, and in a case where the detection device detects the operation of the charging port displaced in the vertical direction during a time period from when the position information acquisition device acquires the position information to when the insertion of the charging connector into the charging port is completed, the acquisition of the position information by the position information acquisition device is newly done again.

Abstract: A vehicle control device mounted on a vehicle capable of external charging, the vehicle control device being configured to: control to cause a state of the vehicle to a first state, in which a movement of the vehicle is prohibited, when receiving an instruction signal from an automatic charging device, which automatically connects a charging connector to a charging port; and release the first state under all of the following conditions are satisfied: a) there is a request for releasing the first state by a user of the vehicle while the vehicle is controlled under the first state, b) the charging connector is not connected to the charging port, and c) there is no obstacle in a traveling direction of the vehicle.

Abstract: An object is to provide an electrode that is easily arranged at a predetermined position when electroporation is performed. The object is achieved by an electrode used for performing electroporation, the electrode includes: at least two or more conductors; and a member configured to hold each conductor and expose at least one end of each of the conductors to outside, the member has a first face where the one end of each of the conductors is exposed, and at least one or more protruding parts provided to the first face, and the length by which the one or more protruding parts protrude in an axis direction from the first face is longer than the length by which the one end of each of the conductors is exposed from the first face.

Abstract: An automatic charging system includes: a vehicle driven by power from a power storage device; a charger equipped with a charging cable having a charging connector; a charging robot equipped with a robot arm, which automatically grasp the charging connector, and insert and remove the charging connector into and from a charging port of the vehicle, so that power is charged to the power storage device; and a control device which causes the vehicle to lock a door and a window, each of which is a closest to the charging port, during at least a charging operation, in which the charging robot receives an instruction to start automatic charging, starts autonomous moving from a predetermined stand-by position, completes charging power to the power storage device, and returns to the predetermined stand-by position.

Abstract: A negative electrode active material for a secondary battery includes composite particles each including a matrix, and a silicon phase dispersed in the matrix. Each of the composite particles is coated with a coating layer. The coating layer is a mixture of a carbon material and a fluorine-containing material.

Abstract: A line narrowing gas laser device includes a line narrowing device, an output coupling mirror, a laser chamber arranged on an optical path of an optical resonator, a first holder which supports the output coupling mirror, a second holder which supports the first holder to be rotatable about a rotation axis of the first holder, and an adjustment device supported by the second holder and being in contact with the first holder to rotate the first holder about the rotation axis. The line narrowing device has a characteristic of changing, into a first direction, beam pointing of laser light output toward the output coupling mirror when temperature inside the line narrowing device rises. The second holder and the adjustment device rotate the first holder in a direction in which a change in the first direction in the beam pointing of the laser light is suppressed by thermal expansion.

Abstract: Provided is an image forming apparatus including a temperature sensing circuit to which a temperature sensing element is electrically connected, wherein a surface of a heater on a side where the temperature sensing element is provided is in contact with the inner surface of a film, a heating element is provided in a primary side circuit which is electrically connected to a commercial power supply, and the temperature sensing circuit is electrically insulated from both of the primary side circuit and a secondary side circuit which is electrically insulated from the primary side circuit.

Abstract: A reaction method includes, in a gas-liquid reaction performed using a solid catalyst, alternately allowing a gaseous raw material that includes a first raw material and a liquid raw material that includes a second raw material to pass through a reaction field that holds the solid catalyst, and reacting the first and second raw materials on the solid catalyst.

Abstract: A downsized lens apparatus in which a degree of freedom in arrangement is improved is provided. A lens apparatus comprises: a first operation member configured to move an optical element along an optical axis direction; a first elastic member configured to transmit a force to the first operation member; a pressing member configured to change a force applied to the first elastic member according to the movement along the optical axis direction; a second operation member configured to move the pressing member along the optical axis direction; and a fixed element configuring at least a part of an exterior unit, wherein the pressing member is movably held by the fixed element along the optical axis direction, and the second operation member is rotatably held by the fixed element.

Abstract: An aqueous polyurethane resin is a chain-extended product of a neutralized product of an isocyanate group-terminated prepolymer which is a reaction product of (a) an organic polyisocyanate, (b) a polyol, (c) a compound having an anionic hydrophilic group and at least two active hydrogens and (d) a polyhydric alcohol, the chain-extended product being obtained by chain-extending the neutralized product with (e) a polyamine having two or more amino groups and/or imino groups, wherein the polyol contains at least one selected from the group consisting of polycarbonate diols each having a structural unit derived from a diol having a branched structure with an integer of 3 to 10 carbon atoms and polycarbonate diols having a structural unit derived from a diol having a linear structure with an odd number of 3 to 9 carbon atoms, and the polyhydric alcohol contains a polyhydric alcohol having at least three or more active hydrogens.

Abstract: A drying device includes a conveying unit to convey a medium to which liquid is discharged from a discharging head, a hot air blowing unit, a passage forming unit, and an adjusting unit. The hot air blowing unit includes a blowing unit, and a heating unit. The passage forming unit forms, between the hot air blowing unit and a region on a conveyance path of the conveying unit, a circulation path through which air blown from the hot air blowing unit is to be circulated. The adjusting unit adjusts an amount of air outside the circulation path that is supplied to the blowing unit. The circulation path includes an introduction portion, and an exhaust portion. The adjusting unit includes a movable member that changes an exhaust portion opening amount.

Abstract: A printing apparatus includes a conveyance belt that supports a medium, a carriage where a printing head is disposed for printing on a medium, and a gap adjusting unit that adjusts the gap between the conveyance belt and the printing head. The gap adjusting unit includes a gap adjusting motor, a power transmission unit including a rotation shaft that rotates with the driving force of the motor, a lifting unit, and a relative displacement mechanism. The lifting unit moves the carriage up and down with the rotational force of the rotation shaft transmitted by the power transmission unit. The relative displacement mechanism relatively displaces one of two members making up at least one of the power transmission unit or the lifting unit in the direction of allowing the upward displacement of the carriage with respect to the other that is in an operation stop state.

Abstract: A power supply shutoff device includes a movable section, a driving section, a power supply device, a power distribution section, an electric power supply circuit, and a supply control section. The movable section is configured to travel on a traveling path provided along a board production line in which multiple board work machines, which perform a predetermined board work on a board, are installed side by side. The driving section is provided in the movable section and configured to cause the movable section to travel by using supply electric power supplied from the board work machine with non-contact power feeding. The supply control section is configured to stop a supply of the electric power to the electric power supply circuit when drive electric power for driving the board work machine is shut off in at least one board work machine among the multiple board work machines.

Abstract: An object of the present invention is to provide a chain that is easy to assemble, has a longer life and smaller size, and allows larger tolerance for misalignment. The object is achieved by a chain including a plurality of outer links each having a pair of outer plates and pins, and a plurality of inner links each having a pair of inner plates and bushings, alternately and pivotably coupled together in the longitudinal direction of the chain by the pins rotatably inserted into the bushings, with a position restricting part positioned between each pair of the inner plates to restrict inward movement of each pair of inner plates in the chain width direction. The bushings are rotatably inserted in respective bushing holes of each pair of inner plates.

Abstract: A reaction device for reacting a liquid-phase reactant and a gas-phase reactant converted into fine bubbles includes: a porous body that includes a plurality of flow paths and in which the flow paths are separated by porous walls, the porous walls include continuous pores, and the porous body includes a reaction catalyst at least on the surface thereof; a solution supply section for supplying a solution containing a gas-phase reactant and a liquid-phase reactant to the continuous pores in the porous body; and a solution discharge section for discharging solution containing a reaction product obtained when the solution flows through the continuous pores of the porous body.

Abstract: The recording device includes an elongated member 79 and a housing section 60. The housing section 60 houses the elongated member 79, and has a fixed end 61, a moving end, and an elongated variable section. A curved portion, which is a portion where the variable section is folded back on the way, moves following the movement of the carriage. In the height direction HD of the housing section 60, film member 76 having flexibility is disposed between the elongated member 79 and the housing section 60. A coefficient of friction between the film member 76 and the elongated member 79 is smaller than a coefficient of friction between the housing section 60 and the elongated member 79.

Abstract: An image forming apparatus includes a processor, in which the processor is configured to acquire operational log data about an operating procedure of a user who issues an instruction to perform image formation processing and display the operating procedure, in a case where a trouble occurs in the image formation processing and an instruction is issued to acquire the operational log data, cause the user to select whether or not the operating procedure is appropriate, and output data for trouble analysis according to a result of the selection of the user.

Abstract: A device produces fine bubbles that has a simple configuration and that is capable of generating fine bubbles. This fine bubble generation device includes: a porous body having continuous pores; a liquid supply section that supplies a liquid to the porous body and causes the liquid to circulate through the continuous pores; and a liquid discharge section for discharging liquid that has circulated through the continuous pores.