Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

Abstract: A joined article including: a resin (1) having a linear expansion coefficient at 30° C. to 200° C. of 17 ppm/° C. or higher and a thickness of 5 to 100 ?m; and a metal joined to a surface of the resin (1) and having a thickness of 5 to 50 ?m. The resin (1) includes a heat-affected layer that is close to the metal and that occupies 80% or less of the thickness of the resin (1), and the joined article is a dielectric material for a substrate. Also disclosed is a substrate including the joined article and a resin (2) stacked on the joined article.

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: A control device for a vehicle including (i) a power transmission device, (ii) a shift operation device that is to be operated by a driver of the vehicle to an operation position corresponding to a shift position of the power transmission device, and (iii) a switching device for switching the shift position of the power transmission device through actuation of an actuator. The control device is configured, upon occurrence of a momentary interruption of a control-device electric-power source that is supplied with an electric power from a vehicle electric-power source, to not perform an initial position learning process for setting a reference position of the actuator, until a shift switching operation for switching the shift position of the power transmission device is performed by a driver of the vehicle.

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: A control device for a vehicle including (i) a power transmission device, (ii) a shift operation device that is to be operated by a driver of the vehicle to an operation position corresponding to a shift position of the power transmission device, and (iii) a switching device for switching the shift position of the power transmission device through actuation of an actuator. The control device is configured, upon occurrence of a momentary interruption of a control-device electric-power source that is supplied with an electric power from a vehicle electric-power source, to not perform an initial position learning process for setting a reference position of the actuator, until a shift switching operation for switching the shift position of the power transmission device is performed by a driver of the vehicle.

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: According to improvement of the receptor layer of various sensors of the type for detecting physical parameters (for example, a surface stress sensor, QCM, and SPR), all of high sensitivity, selectivity, and durability are achieved simultaneously. A porous material or a particulate material, e.g., nanoparticles, is used in place of a uniform membrane which has been conventionally used as a receptor layer. Accordingly, the sensitivity can be controlled by changing the membrane thickness of the receptor layer, the selectivity can be controlled by changing a surface modifying group to be fixed on the porous material or particulate material, and the durability can be controlled by changing the composition and surface properties of the porous material or particulate material.

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: This core-shell composite (10) is provided with a core (11) formed from a porous carbon body having a large number of pores from the interior through to the surface, and a shell layer (12) formed from conductive polymer nanorods (12a) that extend outward from the cavities of the pores (11a) on the surface of the core. The present invention provides the core-shell composite (10), to which electrolyte ions can be efficiently adsorbed or doped, a method for producing the core-shell composite, as well as an electrode material, a catalyst, an electrode, a secondary battery and an electric double-layer capacitor that use the core-shell composite.

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: A vehicle includes a radiator, a bypass passage, a first valve, a second valve, and a controller. Cooling water is circulated through the radiator independently of a cylinder block and a cylinder head of an engine. The radiator cools the cooling water. The cooling water is circulated through the bypass passage while bypassing the radiator. The first valve switches between an open state in which cooling water is circulated through the cylinder block and a closed state in which cooling water is not circulated through the cylinder block. The second valve receives cooling water circulated through the cylinder head and cooling water circulated through the cylinder block via the first valve. The second valve uses an intermediate opening to adjust a flow rate of cooling water circulated through the radiator and the bypass passage. The controller controls opening and closing of the first valve and the opening of the second valve.

Abstract: This core-shell composite (10) is provided with a core (11) formed from a porous carbon body having a large number of pores from the interior through to the surface, and a shell layer (12) formed from conductive polymer nanorods (12a) that extend outward from the cavities of the pores (11a) on the surface of the core. The present invention provides the core-shell composite (10), to which electrolyte ions can be efficiently adsorbed or doped, a method for producing the core-shell composite, as well as an electrode material, a catalyst, an electrode, a secondary battery and an electric double-layer capacitor that use the core-shell composite.

Abstract: An optical reception apparatus (1) of the present invention includes: a local oscillator (11) outputting local oscillation light (22); an optical mixer (12) receiving a multiplexed optical signal (21) and the local oscillation light, and selectively outputting an optical signal (23) corresponding to the wavelength of the local oscillation light from the multiplexed optical signal; a photoelectric converter (13) converting the optical signal (23) output from the optical mixer into an electric signal (24); a variable gain amplifier (15) amplifying the electric signal (24) to generate an output signal (25) whose output amplitude is amplified to a certain level; a gain control signal generating circuit (16) generating a gain control signal (26) for controlling the gain of the variable gain amplifier (15); and a monitor signal generating unit (17) generating a monitor signal (27) corresponding to the power of the optical signal (23) using the gain control signal (26).

Abstract: According to improvement of the receptor layer of various sensors of the type for detecting physical parameters (for example, a surface stress sensor, QCM, and SPR), all of high sensitivity, selectivity, and durability are achieved simultaneously. A porous material or a particulate material, e.g., nanoparticles, is used in place of a uniform membrane which has been conventionally used as a receptor layer. Accordingly, the sensitivity can be controlled by changing the membrane thickness of the receptor layer, the selectivity can be controlled by changing a surface modifying group to be fixed on the porous material or particulate material, and the durability can be controlled by changing the composition and surface properties of the porous material or particulate material.

Abstract: A vehicle includes a radiator, a bypass passage, a first valve, a second valve, and a controller. Cooling water is circulated through the radiator independently of a cylinder block and a cylinder head of an engine. The radiator cools the cooling water. The cooling water is circulated through the bypass passage while bypassing the radiator. The first valve switches between an open state in which cooling water is circulated through the cylinder block and a closed state in which cooling water is not circulated through the cylinder block. The second valve receives cooling water circulated through the cylinder head and cooling water circulated through the cylinder block via the first valve. The second valve uses an intermediate opening to adjust a flow rate of cooling water circulated through the radiator and the bypass passage. The controller controls opening and closing of the first valve and the opening of the second valve.