Abstract: A method of manufacturing an optical coupler that includes: preparing a light-transmitting substrate having a first main surface and a second main surface aligned in a first direction; applying a first photosensitive glass paste containing a first filler to the first main surface; arranging a grayscale mask formed in a binary pattern on the second main surface; emitting an ultraviolet ray to the second main surface to expose the first photosensitive glass paste; removing the grayscale mask from the second main surface and developing the first photosensitive glass paste; and removing the light-transmitting substrate from the first photosensitive glass paste developed and curing the first photosensitive glass paste, wherein a longest length of the first filler is larger than a wavelength of the ultraviolet ray.

Abstract: A display switching device according to one or more embodiments may include a lens array including an array of a plurality of lenses and a display unit. Light from each of the plurality of light source positions transmits through a different position on the display unit and is focused by a corresponding lens. A transmittance on the display unit through which the light transmits differs depending on a position on the display unit. The transmittance at a position of a plurality of positions on the display unit is a transmittance of one of three or more types.

Abstract: To provide a tubular body kit usable in stably preparing a liquid containing a desired component from blood or the like. The tubular body kit includes a tubular body, and a gasket movable in a tube axial direction in the tubular body, the tubular body includes a storage chamber partitioned by the gasket, the storage chamber being configured to store a liquid, and the gasket includes a first surface facing the storage chamber, the first surface having a flat surface shape or a recessed surface shape, the first surface including a first recessed portion.

Abstract: A syringe system includes a first syringe, a second syringe, and at least any one of a first buoy located inside a first syringe barrel or a second buoy located inside a second syringe barrel. The first syringe includes the first syringe barrel. The second syringe includes the second syringe barrel coupled to the first syringe in such a manner that at least part of the second syringe barrel is movable from inside the first syringe barrel.

Abstract: An exothermic reaction apparatus includes a reactor capable of accommodating a nanocomposite metal material, a cutoff unit provided in a gas pipe to cut off a supply of hydrogen to the reactor, a measurement unit that measures an occlusion rate of hydrogen in the nanocomposite metal material accommodated in the reactor, and a controller that controls the exothermic reaction apparatus. The controller controls the occlusion rate of hydrogen in the nanocomposite metal material accommodated in the reactor to a value within a range of 1.0 or more and 3.5 or less by controlling the cutoff unit during an exothermic reaction to stop the supply of hydrogen into the reactor when the occlusion rate of hydrogen in the nanocomposite metal material based on a measurement result obtained with the measurement unit approaches a predetermined value and to resume the supply of hydrogen into the reactor a predetermined time after.

Abstract: A culture container (1) having a guide thread (31) and a plurality of cells (32) that is capable of culturing a regenerative hair follicle germ (30), wherein the culture container (1) is equipped with a first recess (10) and a second recess (20) and the second recess (20) has a second bottom (22) where the guide thread (31) can be positioned in the center of an opening (23) and a method for producing a regenerative hair follicle germ that includes a step for aggregating a cell population including epithelial cells (32a) within the second recess (20) of the culture container (1), a step for aggregating a cell population including mesenchymal cells (32b) within the second recess (20), a step for inserting the guide thread (31) into the second recess (20), and a step for culturing the cell population including epithelial cells (32a) and the mesenchymal cells (32b).

Abstract: A mover control system according to an embodiment includes a controller, a node generator, and a path generator. The controller controls a mover traveling within a predetermined area. The node generator generates a pair of specified nodes at respective arbitrary locations on a map corresponding to the predetermined area. The pair of specified nodes are nodes where the mover is controllable. The path generator generates a path between the pair of specified nodes. The controller makes the mover travel along a traveling route corresponding to the path within the predetermined area.

Abstract: To provide means for efficient growth of epithelial cells capable of being used to manufacture regenerated hair follicle germs. Provided are a culture medium for growth of epithelial cells capable of being used to manufacture regenerated hair follicle germs, the culture medium comprising basal medium and at least (1) through (3), below: and a method for growing the epithelial cells using the culture medium: (1) at least one species of BMP inhibitor: (2) at least one species of fibroblast growth factor: and (3) at least one species of sonic hedgehog (SHH) and/or SHH agonist.

Abstract: Provided is a compound that can promote angiogenesis by inhibiting the function of TSP1, and is useful for the treatment or prophylaxis of diseases such as critical limb ischemia.

Abstract: The present invention provides a method for producing regenerated hair follicle primordium that allows production of regenerated hair follicle primordium more easily and in larger amounts compared to conventional production methods. A method for producing regenerated hair follicle primordium comprising a step of obtaining hair follicle primordium by culturing a first population of cells comprising epithelial cells and a second population of cells comprising mesenchymal cells while allowing them to be in contact is provided. The production method of the present invention is characterized in that at least either one of said first population of cells and said second population of cells has formed cell aggregates before said contact, and a culture support is not used when contacting the other population of cells with said cell aggregate.

Abstract: The present invention provides a modified atrial natriuretic peptide that exhibits prolonged duration in blood and maintains cGMP elevating activity. The present invention provides a modified peptide in which at least one sugar substance is linked directly through a glycosidic bond or via a linker structure to at least one hANP peptide, or a pharmaceutically acceptable salt thereof, a medicament comprising the modified peptide or the salt thereof as an active ingredient, etc.

Abstract: The present invention provides a modified atrial natriuretic peptide that exhibits prolonged duration in blood and maintains cGMP elevating activity. The present invention provides a modified peptide in which at least one sugar substance is linked directly through a glycosidic bond or via a linker structure to at least one hANP peptide, or a pharmaceutically acceptable salt thereof, a medicament comprising the modified peptide or the salt thereof as an active ingredient, etc.

Abstract: Provided is a compound that can promote angiogenesis by inhibiting the function of TSP1, and is useful for the treatment or prophylaxis of diseases such as critical limb ischemia.

Abstract: A mover control system according to an embodiment includes a controller, a node generator, and a path generator. The controller controls a mover traveling within a predetermined area. The node generator generates a pair of specified nodes at respective arbitrary locations on a map corresponding to the predetermined area. The pair of specified nodes are nodes where the mover is controllable. The path generator generates a path between the pair of specified nodes. The controller makes the mover travel along a traveling route corresponding to the path within the predetermined area.

Abstract: A rotary electric machine includes: a stator; a rotor; a control device that causes the stator to generate a rotating magnetic field; and a magnetic flux supply element supported by a rotary shaft so as to be rotatable relative to the rotary shaft, disposed radially inward of the rotor across a gap, and having auxiliary magnets. Each auxiliary magnet is formed such that opposite end portions thereof in the circumferential direction are radially opposed to holding magnets when the relative rotation angle of the magnetic flux supply element is a strengthening angle. The control device executes field weakening control or field strengthening control, thereby changing the relative rotation angle of the magnetic flux supply element.

Abstract: The present invention provides a modified atrial natriuretic peptide that exhibits prolonged duration in blood and maintains cGMP elevating activity. The present invention provides a modified peptide in which at least one sugar substance is linked directly through a glycosidic bond or via a linker structure to at least one hANP peptide, or a pharmaceutically acceptable salt thereof, a medicament comprising the modified peptide or the salt thereof as an active ingredient, etc.

Abstract: A method for aligning proteins is provided. The method for aligning the proteins (20 and 32) is capable of aligning proteins (20 and 32) on the substrate (10) comprising carbon. The proteins (20 and 32) are used as structures comprising a cellulose binding domain (22) of the cellulosome and a cohesin domain (21), and a protein (30) to be bonded to the protein (20) is used as a protein (32) having a dockerin domain (31). The cohesin domain (21) can be used as an amino-acid sequence for a cohesin domain (21) derived from various microorganisms, and a functional protein can be used as a protein structure having a microbial-species-specific dockerin domain. The protein (20) can be arrayed regularly along a graphite hexagonal-plate-shaped crystal, and any protein (32) having this dockerin domain (20) can be bonded and arranged as an active protein (32) on the graphite (10).

Abstract: The present invention provides a material for a molded resin as a material for a semiconductor light-emitting device that can yield a highly durable (light resistance and heat resistance) molded resin and can also improve the LED output through an excellent reflectivity. The present invention also provides an easily moldable material for a molded resin for a semiconductor light-emitting device. The material for a molded resin for a semiconductor light-emitting device is a resin composition, comprising (A) a polyorganosiloxane, (B) a white pigment, and (C) a curing catalyst, wherein the white pigment (B) has the following characteristics (a) and (b): (a) an aspect ratio 1.2 or more and 4.0 or less, and (b) a primary particle diameter 0.1 ?m or more and 2.0 ?m or less.

Abstract: In saccharification of cellulose, chimeric ?-glucosidase having a region exhibiting thermophilic bacteria-derived ?-glucosidase activity and a module combinable to cellulose is used along with cellulosome, and at the completion of saccharification of cellulose, a cellulosic substrate is added to make the chimeric ?-glucosidase and cellulosome attach to the cellulosic substrate for separation.

Abstract: An object of the present invention is to provide a package from which a metal wiring and the like are difficult to be detached even when heat is generated from a semiconductor light-emitting element. This object is achieved with a package for a semiconductor light-emitting device comprising at least a molded resin containing (A) a SiH-containing polyorganosiloxane and (B) a filler, wherein an amount of SiH existing in the molded resin, after a heat treatment thereof at 200° C. for 10 minutes, is 20 to 65 ?mol/g.