Abstract: Microelectronic assemblies, related devices and methods, are disclosed herein. In some embodiments, a microelectronic assembly may include a first die, having a first surface and an opposing second surface, in a first layer; a redistribution layer (RDL) on the first layer, wherein the RDL is electrically coupled to the second surface of the first die by solder interconnects, and a second die in a second layer on the RDL, wherein the second die is electrically coupled to the RDL by non-solder interconnects.

Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) may transmit a request to a network entity to establish a voice communication session with another UE that may be subscribed to a video service. The UE may transmit an indication of a video streaming parameter for the video service for streaming one-way video transmissions from the network entity to the UE for display during establishment of the voice communication session. The UE may transmit an indication of an updated video streaming parameter to the network entity to reduce the video quality for the video service. The network entity may reduce the video streaming quality for the one or more one-way video transmissions to the UE based on the updated video streaming parameter.

Abstract: A method of ctDNA library construction and sequencing data analysis for simultaneously detecting multiple common mutations in liver cancer. The library construction method and sequencing data analysis process have the following advantages: 1. Simultaneous detection of multiple mutation forms in liver cancer without capturing; 2. Suitable for efficient capture of ultra-small target regions; 3. The library may support 10-20 tests; 4. Ligate the DNA barcode to the starting ctDNA molecule during the library construction process, and cooperate with the biological information analysis process to achieve high specific detection of low-frequency mutations in ctDNA; 5. The library is usable for PCR hot spots detection and sequencing by a capture method at the same time, the added DNA barcode may effectively filter out false positive mutations and achieve high-specificity sequencing based on duplex.

Abstract: The present disclosure is directed to an apparatus having a bond head configured to heat and compress a semiconductor package assembly, and a bonding stage configured to hold the semiconductor package assembly, wherein the bonding stage comprises a ceramic material including silicon and either magnesium or indium.

Abstract: Embodiments disclosed herein include package architectures. In an embodiment, the package architecture comprises a package substrate, a first bridge in the package substrate, where the first bridge includes conductive routing, and a second bridge in the package substrate. In an embodiment, the package architecture further comprises a third bridge in the package substrate, where the second bridge and the third bridge are positioned symmetrically about the first bridge.

Abstract: A high-efficiency yield-increasing exploitation method for natural gas hydrates includes steps of drilling of natural gas hydrate reservoirs along horizontal wells, seepage increasing by fracturing for fracture forming and stability improvement by grouting in the natural gas hydrate reservoirs, and yield improvement by combined exploitation of depressurization of the horizontal wells and heat injection; according to the present invention, drilling time is shortened by rapid drilling along the horizontal wells, the permeability of the reservoirs can be effectively improved by fracturing for fracture forming, the stability of the reservoirs can be improved by injecting foam cement slurry into the reservoirs, and the yield of the natural gas hydrates can be improved by the combined exploitation method of depressurization of the horizontal wells and heat injection.

Abstract: A high-efficiency yield-increasing exploitation method for natural gas hydrates includes steps of drilling of natural gas hydrate reservoirs along horizontal wells, seepage increasing by fracturing for fracture forming and stability improvement by grouting in the natural gas hydrate reservoirs, and yield improvement by combined exploitation of depressurization of the horizontal wells and heat injection; according to the present invention, drilling time is shortened by rapid drilling along the horizontal wells, the permeability of the reservoirs can be effectively improved by fracturing for fracture forming, the stability of the reservoirs can be improved by injecting by the combined exploitation method of depressurization of the horizontal wells and heat injection.

Abstract: A preparation method for a piezoelectric fiber is provided including a piezoelectric functional layer and an insulating layer coated on the piezoelectric functional layer. The piezoelectric functional layer includes a piezoelectric composite layer of a spiral winding structure, and the piezoelectric composite layer includes a first piezoelectric layer, a conductive layer and a second piezoelectric layer that are sequentially stacked. The preparation method includes taking one end of the piezoelectric composite layer as a winding axis, winding the piezoelectric composite layer in a direction perpendicular to the winding axis to form the piezoelectric functional layer, wherein turns of winding the piezoelectric composite layer are greater than 5, coating the piezoelectric functional layer with the insulating layer, and vacuum heating to consolidate, to prepare a preform rod.

Abstract: The present invention discloses a method for detecting the mutation and methylation of tumor-specific genes in ctDNA, and this method can simultaneously detect the mutation (including point mutation, insertion-deletion mutation, HBV integration and other mutation forms) and/or methylation of tumor-specific genes in ctDNA in one sample. Not only the sample size requirement is low, but the MC library prepared by this method can support 10-20 subsequent detections. The results of each test can represent the mutation status of all the original ctDNA specimens and the methylation modification status of the region covered by the restriction sites, without reducing the sensitivity and specificity. The present invention has important clinical significance for early tumor screening, disease tracking, efficacy evaluation, prognosis prediction and the like, and has great application value.

Abstract: The present disclosure provides a functional candy with a special effect on gastrointestinal regulation and an industrialized production method thereof. The method includes: step 1, preparing a yacon polysaccharide-peptide-zinc chelate with a high activity; step 2, mixing 1 part to 5 parts of the yacon polysaccharide-peptide-zinc chelate with 10 parts to 20 parts of a chicory extract powder, 10 parts to 20 parts of a Hericium erinaceus extract powder, 5 parts to 15 parts of xylooligosaccharide, 5 parts to 15 parts of fructooligosaccharide, and 10 parts to 20 parts of water well to prepare a main agent; and step 3, adding an auxiliary agent including other ingredients to the main agent to prepare the functional candy. The present disclosure further provides a functional candy with a special effect on gastrointestinal regulation prepared by the method.

Abstract: A preparation method tor a piezoelectric fiber is provided including a piezoelectric functional layer and an insulating layer coated on the piezoelectric functional layer. The piezoelectric functional layer includes a piezoelectric composite layer of a spiral winding structure, and the piezoelectric composite layer includes a first piezoelectric layer, a conductive layer and a second piezoelectric layer that are sequentially stacked. The preparation method piezoelectric composite layer in a direction perpendicular to the winding axis to form the piezoelectric functional layer, wherein turns of winding the piezoelectric composite layer are greater than 5, coating the piezoelectric functional layer with the insulating layer, and vacuum heating to consolidate, to prepare a preform rod.

Abstract: Provided are innovative compositions for tethering blocking an inactivating of airborne respiratory infectious viruses. The compositions comprise bispecific proteins with two different antigen binding regions (ABR), which are typically configured as immunoglobulin “single variable domains” (ISV). A first ISV binds to a surface protein found on an airborne infectious virus. A second ISV binds to a mucin protein, e.g. a mucin protein present on ocular, nasopharyngeal, tracheal and/or oral surfaces of a mammal. The two ISV are joined by a polypeptide linker.

Abstract: An anti-propylene mask and method for preparation thereof is provided; the anti-propylene mask includes a fiber cloth contact layer, an antistatic non-woven fabric layer and a fullerene/nano titanium dioxide spunbond layer which are arranged in sequence; the fullerene/nano titanium dioxide spunbond layer is made by spun-bonding the modified resin material into a fiber web; the raw materials of modified resin materials include matrix resin, carboxylated fullerene derivatives, nano titanium dioxide, a lubricant, and a coupling agent; the modified resin material is prepared by following method: the carboxylated fullerene derivative is mixed and reacted with the nano titanium dioxide to prepare the carboxylated fullerene derivative-modified nano titanium dioxide, which is then blended and extruded with the remaining components in the raw material, and thus prepared. The mask can prevent propylene from entering the human body through the human respiratory organs and has a good anti-propylene effect.

Abstract: A semiconductor package includes a semiconductor subassembly disposed on a package substrate and including: a first layer including first dies, and an encapsulation material encapsulating the first dies; a second layer adjacent the first layer and including a substrate; a solid component disposed on the first layer; and an interface layer disposed between and mechanically bonding the solid component and the first layer. The interface layer provides a direct dielectric-to-dielectric bond including a first dielectric sublayer directly adjacent the first layer, and a second dielectric sublayer directly adjacent the first dielectric sublayer and including an amorphous material. Second dies may be disposed on the package substrate adjacent the semiconductor subassembly.

Abstract: There is provided a cobalt-based alloy product comprising: in mass %, 0.08-0.25% C; 0.1% or less B; 10-30% Cr; 5% or less Fe and 30% or less Ni, the total amount of Fe and Ni being 30% or less; W and/or Mo, the total amount of W and Mo being 5-12%; at least one of Ti, Zr, Hf, V, Nb and Ta, the total amount of Ti, Zr, Hf, V, Nb and Ta being 0.5-2%; 0.5% or less Si; 0.5% or less Mn; 0.003-0.04% N; and the balance being Co and impurities. The product is a polycrystalline body of matrix phase crystal grains. In the matrix phase crystal grains, post-segregation cells with an average size of 0.13-2 ?m are formed, wherein components constituting an MC type carbide phase comprising Ti, Zr, Hf, V, Nb and/or Ta are segregated along boundary regions of the post-segregation cells.

Abstract: Microelectronic assemblies, related devices and methods, are disclosed herein. In some embodiments, a microelectronic assembly may include a first die, having a first surface and an opposing second surface, in a first layer; a redistribution layer (RDL) on the first layer, wherein the RDL is electrically coupled to the second surface of the first die by solder interconnects, and a second die in a second layer on the RDL, wherein the second die is electrically coupled to the RDL by non-solder interconnects.

Abstract: A metal-powder producing apparatus includes a spray chamber, and a plurality of spray nozzles that liquid-spray a melted metal into the spray chamber. Each of the plurality of spray nozzles includes: a liquid nozzle that allows the melted metal to flow down into the spray chamber; and a gas-jet nozzle that has a plurality of gas-jet holes arranged around the liquid nozzle and causing a gas fluid to collide with the melted metal having flowed down from the liquid nozzle.

Abstract: In various embodiments, a layer of organic encapsulant is provided over a surface of an ultraviolet (UV) light-emitting semiconductor die, and at least a portion of the encapsulant is exposed to UV light to convert at least some of said portion of the encapsulant into non-stoichiometric silica material. The non-stoichiometric silica material includes silicon, oxygen, and carbon, and a carbon content of the non-stoichiometric silica material is greater than 1 ppm and less than 40 atomic percent.

Abstract: There is provided a cobalt-based alloy product comprising: in mass %, 0.08-0.25% C; 0.1% or less B; 10-30% Cr; 5% or less Fe and 30% or less Ni, the total amount of Fe and Ni being 30% or less; W and/or Mo, the total amount of W and Mo being 5-12%; 0.5% or less Si; 0.5% or less Mn; 0.003-0.04% N; 0.5 to 2 mass % of an M component being a transition metal other than W and Mo and having an atomic radius of more than 130 pm; and the balance being Co and impurities. The impurities include 0.5% or less Al and 0.04% or less O. The product is a polycrystalline body of matrix phase crystal grains. In the matrix phase crystal grains, segregation cells with an average size of 0.13-2 ?m are formed, in which the M component is segregated in boundary regions of the segregation cells.

Abstract: A Co-based alloy heat exchanger comprises: in mass %, 0.08-0.25% C; 0.1% or less B; 10-30% Cr; 5% or less Fe and 30% or less Ni, the total amount of Fe and Ni being 30% or less; W and/or Mo, the total amount of W and Mo being 5-12%; Ti, Zr, Nb and Ta, the total amount of Ti, Zr, Nb and Ta being 0.5-2%; 0.5% or less Si; 0.5% or less Mn; 0.003-0.04% N; and the balance being Co and impurities. The impurities include 0.5% or less Al, and 0.04% or less O. The heat exchanger is a polycrystalline body of matrix crystal grains with an average size of 5-100 ?m. In the matrix crystal grains, segregation cells with an average size of 0.13-2 ?m are formed, wherein components constituting an MC type carbide comprising Ti, Zr, Nb and/or Ta are segregated in boundary regions of the segregation cells.