Abstract: A sealant delivery device includes a delivery tube, a bioadhesive container, and an adapter. The delivery tube includes proximal and distal ends. The bioadhesive container holds a sealant activator and a sealant precursor separated from each other. The adapter is interposed between the delivery tube and the bioadhesive container. The adapter includes a first channel member that couples a first lumen of the delivery tube to the sealant activator, and a second channel member that couples the first lumen to the sealant precursor. The adapter provides separation of the sealant activator and the sealant precursor until a position distal of the bioadhesive container.

Abstract: Wound closure devices, systems, and methods may be used to close an opening, such as a puncture wound or incision, formed in tissue, such as heart tissue. A wound closure device may be configured and adapted to be placed within the puncture wound or incision to close and/or seal the puncture wound or incision. A bioadhesive may be used to strengthen the closure and/or seal of the puncture wound after placement of the wound closure device relative to the puncture wound.

Abstract: A vascular closure device that includes an inflation tube, a flashback tube, a dual lumen tube, a bond portion, and an inflatable balloon. The inflation tube defines an inflation lumen. The flashback tube defines a flashback lumen. The dual lumen tube has first and second lumens and is positioned distal of the inflation tube and flashback tube. The inflation tube and flashback tube are integrally connected to the dual lumen tube at the bond portion with the inflation lumen in fluid communication with the first lumen and the flashback lumen in fluid communication with the second lumen. The inflatable balloon is mounted at a distal end of the dual lumen tube and is in fluid communication with the inflation lumen.

Abstract: A vascular closure assembly configured to seal a puncture in a vessel that is accessible through a tissue tract. The vascular closure assembly includes a vascular closure device comprising a handle assembly, an insertion shaft, an anchor assembly, and at least one suture member. The insertion shaft extends distally from the handle assembly and carries a plurality of needles. The needles are operable to position at least one suture across the vessel puncture. The anchor assembly is positioned distal of the insertion shaft. The at least one suture member is positioned distal of the insertion shaft. The insertion shaft extends into the tissue tract to position the anchor assembly through the puncture and into the vessel and includes a first depth indicator on an outer surface thereof that indicates a depth of the tissue tract.

Abstract: A vascular closure system includes a body portion, an anchor, a suture carrying portion, and a plurality of needles. The body portion has a distal end surface. The anchor is positionable through a vessel puncture in a vessel wall of a vessel. The anchor defines a vessel contact surface, wherein withdrawal of the anchor captures a portion of the vessel wall between the vessel contact surface and the distal end surface. The suture carrying portion is positionable through the vessel puncture and carries at least one suture member. The plurality of needles extend through the portion of the vessel wall adjacent to the vessel puncture and are configured to connect to the at least one suture member. Withdrawal of the plurality of needles through the portion of the vessel wall positions the at least one suture member through the portion of the vessel wall.

Abstract: A method and apparatus for sealing a puncture or incision formed percutaneously in a tissue. The apparatus including an anchor, a sealing plug, a filament secured to the sealing plug and the anchor, a compaction member assembly, a spool, a driving plate, and a follower. The compaction member assembly is disposed adjacent the sealing plug and structured and arranged to apply an axially directed compressive force to automatically compact the sealing plug toward the anchor. The spool has a portion of the filament wound thereon. The driving plate is connected to the spool and arranged to contact and apply a force to a proximal end of the compaction member assembly upon rotation of the driving plate to advance the compaction member assembly. The follower is operable between the spool and driving plate to releasably connect the spool and driving plate to provide a clutch action.

Abstract: A tissue puncture closure device includes an anchor, a sealing plug, a compaction member, a suture, and a suture cutting member. The compaction member is configured to compress the sealing plug toward the anchor. The suture is coupled to the sealing plug and anchor, and a portion of the suture extends through at least a portion of the compaction member. The suture cutting member extends through an aperture in a sidewall of the compaction member and is operable to cut the suture at a location within the compaction member.

Abstract: A vascular closure device that includes an inflation tube, a flashback tube, a dual lumen tube, a bond portion, and an inflatable balloon. The inflation tube defines an inflation lumen. The flashback tube defines a flashback lumen. The dual lumen tube has first and second lumens and is positioned distal of the inflation tube and flashback tube. The inflation tube and flashback tube are integrally connected to the dual lumen tube at the bond portion with the inflation lumen in fluid communication with the first lumen and the flashback lumen in fluid communication with the second lumen. The inflatable balloon is mounted at a distal end of the dual lumen tube and is in fluid communication with the inflation lumen.

Abstract: A vascular closure device (200) includes a carrier tube (202), an anchor (208), a sealing pad (210), and a suture (204). The carrier tube defines a first lumen (268) and comprises a distal portion (260) and a proximal portion (262). The carrier tube is insertable through an insertion sheath (216). The anchor is positioned outside of the carrier tube. The sealing pad is positioned inside the first lumen. The suture couples the sealing pad to the anchor. The distal portion of the carrier tube has a different material composition from the proximal portion.

Abstract: A method and apparatus for sealing a puncture or incision formed percutaneously in a tissue. The apparatus including an anchor, a sealing plug, a filament connected between the sealing plug and the anchor, a compaction member assembly, a spool and a driving plate. The compaction member assembly being disposed adjacent the sealing plug and structured and arranged to apply an axially directed compressive force to automatically compact the sealing plug toward the anchor. The spool has a portion of the filament wound thereon. The driving plate being connected to the spool and having a cam surface portion. The cam surface portion is arranged to contact a proximal end of the compaction member assembly upon rotation of the spool to advance a distal end of the compaction member assembly.

Abstract: A tissue puncture closure device includes an anchor, a sealing pad, a compaction member, a suture, and a suture cutting member. The compaction member is configured to compress the sealing pad toward the anchor. The compaction member includes a sidewall and a first aperture defined in the sidewall. The suture cutting member is positioned in the compaction member and includes a suture cutting member sidewall and a second aperture defined in the suture cutting member sidewall. The suture is coupled to the sealing pad and anchor, and a portion of the suture extends through the first and second apertures. Relative movement between the compaction member and the suture cutting member severs the suture.

Abstract: A catheter assembly and related methods directed to stent edge protection for an edge of a stent. One example stent edge protect member is positioned with a distal end portion of the stent edge protect member arranged proximal of and adjacent to a proximal end of the stent. The stent edge protect member defines an outer surface that transitions from an outer surface of the stent at the proximal end of the stent to an outer surface of the catheter branch on which the stent edge protect member is positioned. The stent edge protect member can be positioned on a single catheter branch or multiple catheter branches.

Abstract: A side catheter branch of a catheter assembly is oriented with respect to the main or side balloons of a catheter assembly. In some examples, the orientation is accomplished by connecting the side catheter branch to the main and/or side balloons or waste portions thereof. In other examples, the side catheter branch is positioned within the folds of the main or side balloons during assembly of the catheter assembly. In this manner, the side catheter branch remains in a known orientation with respect to the main and/or side balloons prior to and/or after deployment.

Abstract: A catheter shaft bond arrangement includes a first catheter shaft defining a first lumen, a second catheter shaft defining a second lumen, and a first bonding member. The first bonding member is configured to bond with the first and second catheter shafts to create a molded bond upon application of heat to the first bonding member. The molded bond provides a fixed axial and radial orientation of the first and second catheter shafts relative to each other. The molded bond can be generated in some arrangements without the use of the first bonding member. In other arrangements, two or more bonding members can be used to create the molded bond.