Patents by Inventor Zhan Gao

Zhan Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Light waveguide cable for use in high-tension systems
    Patent number: 6434304
    Abstract: In order to prevent an optical cable which is used with a high-tension cable from being damaged by Corona discharge, the optical cable has a cable cladding, provided with a Corona-resistant skin layer.
    Type: Grant
    Filed: January 28, 2000
    Date of Patent: August 13, 2002
    Assignee: CCS Technology, Inc.
    Inventors: Zhan Gao, Ulrich Greiner, Rainer Kamps
  • Light waveguide cable for use in high-tension systems
    Publication number: 20010053269
    Abstract: In order to prevent an optical cable which is used with a high-tension cable from being damaged by Corona discharge, the optical cable has a cable cladding provided with a Corona-resistant skin layer.
    Type: Application
    Filed: January 28, 2000
    Publication date: December 20, 2001
    Inventors: Zhan Gao, Ulrich Greiner, Rainer Kamps
  • Phenyl-substituted 1,4-dihydropyridines
    Publication number: 20010034451
    Abstract: Novel phenyl-substituted 1,4-dihydropyridines, prepared by reacting halogenophenyl-aldehydes with &bgr;-ketoesters, if appropriate with isolation of the ylidene compounds and enamines. The substances can be employed as active compounds in medicaments, in particular in cerebrally active compositions.
    Type: Application
    Filed: February 12, 2001
    Publication date: October 25, 2001
    Inventors: Heinrich Meier, Wolfgang Hartwig, Bodo Junge, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • Phenyl-substituted 1,4-dihydropyridines
    Patent number: 6239155
    Abstract: Novel phenyl-substituted 1,4-dihydropyridines, prepared by reacting halogenophenyl-aldehydes with &bgr;-ketoesters, if appropriate with isolation of the ylidene compounds and enamines. The substances can be employed as active compounds in medicaments, in particular in cerebrally active compositions.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: May 29, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinrich Meier, Wolfgang Hartwig, Bodo Junge, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • 4-phenyl-3-substituted 1,4-dihydropyridine esters
    Patent number: 6066655
    Abstract: 4-Phenyl-3-substituted 1,4-dihydropyridine esters are prepared by reaction of benzaldehydes with ketoesters and enamines, if appropriate with isolation of the ylidene intermediate products, or by esterification of corresponding dihydropyridinecarboxylic acids with alcohols.The new 4-phenyl-3-substituted 1,4-dihydropyridine esters can be employed as active compounds in medicaments for the treatment of the central nervous system, in particular as cerebral therapeutics.
    Type: Grant
    Filed: December 10, 1997
    Date of Patent: May 23, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinrich Meier, Wolfgang Hartwig, Bodo Junge, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • Heterocyclyl substituted dihydropyridines
    Patent number: 6001857
    Abstract: 4-Heterocyclyl-substituted dihydropyridines are prepared by reacting appropriate aldehydes with .beta.-keto esters and aminocrotonic acid esters, or by esterifying 4-heterocyclyl-substituted dihydropyridinecarboxylic acids. The 4-heterocyclyl-substituted dihydropyridines can be employed in medicaments, in particular for the treatment of disorders of the central nervous system.
    Type: Grant
    Filed: July 30, 1997
    Date of Patent: December 14, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bodo Junge, Wolfgang Hartwig, Heinrich Meier, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • 4-phenyl-3-substituted 1,4-dihydropyridine esters
    Patent number: 5731333
    Abstract: 4-Phenyl-3-substituted 1,4-dihydropyridine esters are prepared by reaction of benzaldehydes with ketoesters and enamines, if appropriate with isolation of the ylidene intermediate products, or by esterification of corresponding dihydropyridinecarboxylic acids with alcohols.The new 4-phenyl-3-substituted 1,4-dihydropyridine esters can be employed as active compounds in medicaments for the treatment of the central nervous system, in particular as cerebral therapeutics.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: March 24, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinrich Meier, Wolfgang Hartwig, Bodo Junge, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • Isopropyl 2-methoxyethyl 4-(2-chloro-3-cyano-phenyl)-1, 4-dihydro-2,6-dimethyl-pyridine-3,5-dica rboxylate
    Patent number: 5665740
    Abstract: The present invention relates to the new compound rac-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyano-phenyl)1,4 -dihydro-2,6-dimethylpyridine-3,5-dicarboxylate and its pure enantiomers, processes for their preparation and their use as medicaments, in particular for the treatment of cerebral and neuronal disorders, and a new intermediate for their preparation.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: September 9, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinrich Meier, Wolfgang Hartwig, Bodo Junge, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • Aryl-substituted alkoxycarbonyl-1,4-dihydropyridine-5-carboxylic acid esters
    Patent number: 5658934
    Abstract: The invention relates to new aryl-substituted alkoxycarbonyl-1,4-dihydropyridine-5-carboxylic acid esters, processes for their preparation and their use in medicaments, in particular as agents having a cerebral action.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: August 19, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinrich Meier, Wolfgang Hartwig, Bodo Junge, Ulrich Niewohner, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • 4-heterocyclyl-substituted dihydropyridines
    Patent number: 5502064
    Abstract: 4-Heterocyclyl-substituted dihydropyridines are prepared by reacting appropriate aldehydes with .beta.-keto esters and aminocrotonic acid esters, or by esterifying 4-hetero-cyclyl-substituted dihydropyridinecarboxylic acids. The 4-heterocyclyl-substituted dihydropyridines can be employed in medicaments, in particular for the treatment of disorders of the central nervous system.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: March 26, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bodo Junge, Wolfgang Hartwig, Heinrich Meier, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • Substituted derivatives of deoxymyoinositol, process for their preparation and their use in medicaments
    Patent number: 5463087
    Abstract: A process for the preparation of a compound. That compound is converted to a novel compound of the formula ##STR1## in which R.sup.1, R.sup.2 and R.sup.5 each independently is alkyl of 3 to 14 carbon atoms, which is used to make novel anti-inflammatories.
    Type: Grant
    Filed: January 13, 1995
    Date of Patent: October 31, 1995
    Assignee: Bayer Pharma
    Inventors: Erwin Bischoff, Zhan Gao, Stefan Wohlfeil, Gabriele Hecker, Jeannine Cleophax, Didier Dubreuil, Stephane Gero, Alice Olesker, Catherine Verre-Sebrie, Mauro Vieira de Almeida, Georges Vass
  • Substituted derivatives of deoxymyoinositol, process for their preparation and their use in medicaments
    Patent number: 5407923
    Abstract: Substituted derivatives of deoxymyoinositol of general formula (I): ##STR1## in which R.sup.1, R.sup.2 and R.sup.5 are identical or different and represent a linear or branched alkyl group of 3 to 14 carbon atoms.R.sup.3 and R.sup.4 are identical or different and represent a hydrogen atom, a protecting group of the hydroxyl groups or the residue of formula --CO--(CH.sub.2).sub.n --CH.sub.3in whichn represents the number 12, 13, 14, 15, 16 or 17, and their salts, process for preparing them and their use in medicaments.
    Type: Grant
    Filed: August 12, 1993
    Date of Patent: April 18, 1995
    Assignee: Bayer Pharma
    Inventors: Erwin Bischoff, Zhan Gao, Stefan Wohlfeil, Gabriele Hecker, Jeannine Cleophax, Didier Dubreuil, Stephane Gero, Alice Olesker, Catherine Verre-Sebrie, Mauro V. de Almeida, Georges Vass
  • 4-heterocyclophenyl-substituted dihydropyridines
    Patent number: 5403849
    Abstract: 4-Heterocyclophenyl-substituted dihydropyridines ##STR1## are prepared either by reacting suitable aldehydes with amino esters and .beta.-keto esters, or preparing the heterocyclic substituents of the 4-phenyl by cyclization of corresponding amidines or hydrazides, or esterifying dihydropyridinecarboxylic acids, which are already substituted by heterocyclic radicals, with corresponding alcohols. The 4-heterocyclophenyl-substituted dihydropyridines can be employed in medicaments, in particular for treatment of diseases of the central nervous system.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: April 4, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rudolf Schohe-Loop, Wolfgang Hartwig, Bodo Junge, Heinrich Meier, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman