Abstract: Disclosed is a compound of formula I, a pharmaceutically acceptable salt, or a tautomer thereof. formula I. R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen, methyl group, tert-butyl group, methoxy group, difluoromethyl, trifluoromethyl, trifluoromethoxy, nitro, halogen, phenyl and aromatic heterocyclic; R5 is a hydrogen or halogen; and R6 is hydrogen, C1-4 alkane or C1-4 cycloalkane.

Abstract: The present invention is to provide a MEMS wave gyroscope with improved sensitivity. The MEMS wave gyroscope includes a base; an anchor structure fixed to the base; and a volatility structure suspended above the base. The volatility structure includes N horizontal beams and M straight beams for being interlaced to form M nodes. The horizontal beam is divided into M?1 first beam units by the nodes. The straight beam is divided into N?1 second beam units by the nodes. A first in-surface transducer is formed by the second beam unit coupled with a mechanical field and an electric field of the second beam unit on two opposite sides along the second axis. A first out-surface transducer is formed by at least one of two opposite sides of the second beam coupled with the mechanical field and electric field of the second beam unit.

Abstract: Disclosed are a method and device for implementing an ad hoc network routing protocol in a multi-agent system. The device includes a trajectory information acquisition module, a data packet delivery module, a delivery confirmation module, a data packet forwarding module, a data transmission feedback module and a data storage module. The method includes: acquiring a separation and rendezvous timing table and an adjacency matrix of an ad hoc network composed of multiple agents at a given moment; if a source node has message sending requirement, performing data packet delivery and delivery confirmation based on the separation and rendezvous timing table and the adjacency matrix; and performing data packet forwarding and transmission status feedback by a non-source node.

Abstract: A fabrication method for stretchable/conformable electronic and optoelectronic circuits and the resulting circuits. The method may utilize a variety of electronic materials including, but not limited to Silicon, GaAs, InSb, Pb Se, CdTe, organic semiconductors, metal oxide semiconductors and related alloys or hybrid combinations of the aforementioned materials. While a wide range of fabricated electronic/optoelectronic devices, circuits, and systems could be manufactured using the embodied technology, a hemispherical image sensor is an exemplary advantageous optoelectronic device that is enabled by this technology. Other applications include but are not limited to wearable electronics, flexible devices for the internet-of-things, and advanced imaging systems.

Abstract: A method of preparing a Polygoni Milletii Rhizome tincture includes: preparing a first mixture; extracting the first mixture with 70-90% ethanol under reflux condition to obtain a first extract solution; preparing a second mixture; extracting the second mixture with 50-70% ethanol to obtain a second extract solution; and mixing the first extract solution with the second extract solution to obtain the polygoni milletii rhizome tincture. A method of preparing a Polygoni Milletii Rhizome poultice includes: reparing a Polygoni Milletii Rhizome mixture; mixing the Polygoni Milletii Rhizome mixture and a skin penetration enhancer in water; mixing a moisturizing agent and a binder in water; adding a thickener in water; mixing methylparaben and ethylparaben in 90% ethanol; mixing all solutions to form a mixture; and applying the mixture on a non-woven fabric cloth and drying to form the Polygoni Milletii Rhizome poultice.

Abstract: The present inventions provides drug-drug conjugates, drug-porphyrin conjugates, nanoparticles of the conjugates, as well as modified nanoparticles having PEGylated exteriors or encapsulated by red blood cell vesicles. The conjugates, nanoparticles and nanocarriers are useful for treating cancers and other diseases, as well as for imaging diseased tissue or organs.

Abstract: A compound of formula I or formula II, a pharmaceutically acceptable salt, or a tautomer thereof is disclosed. The Linker is or and n is 1-6.

Abstract: A compound of formula I or formula II, a pharmaceutically acceptable salt, or a tautomer thereof is disclosed. In formula I and II, n is 1-6.

Abstract: The present invention is to provide a MEMS wave gyroscope with improved sensitivity. The MEMS wave gyroscope includes a base; an anchor structure fixed to the base; and a volatility structure suspended above the base. The volatility structure includes N horizontal beams and M straight beams for being interlaced to form M nodes. The horizontal beam is divided into M-1 first beam units by the nodes. The straight beam is divided into N-1 second beam units by the nodes. A first in-surface transducer is formed by the second beam unit coupled with a mechanical field and an electric field of the second beam unit on two opposite sides along the second axis. A first out-surface transducer is formed by at least one of two opposite sides of the second beam coupled with the mechanical field and electric field of the second beam unit.

Abstract: Disclosed are a method and device for implementing an ad hoc network routing protocol in a multi-agent system. The device includes a trajectory information acquisition module, a data packet delivery module, a delivery confirmation module, a data packet forwarding module, a data transmission feedback module and a data storage module. The method includes: acquiring a separation and rendezvous timing table and an adjacency matrix of an ad hoc network composed of multiple agents at a given moment; if a source node has message sending requirement, performing data packet delivery and delivery confirmation based on the separation and rendezvous timing table and the adjacency matrix; and performing data packet forwarding and transmission status feedback by a non-source node.

Abstract: One of the objects of the present invention is to provide a three-axis micromachined gyroscope which improves the detection sensitivity for detecting angular velocity. Accordingly, the present invention provides a three-axis micromachined gyroscope, including: a base; a vibration part suspended by the base, including a vibration assembly for receiving Coriolis force and generating a position change; a drive electrode for driving the vibration part; a detection part connected with the vibration part for detecting position change of the weights after receiving Coriolis force, and converting the position change of the weight into an electrical signal for outputting; and a swing center of each weight being outside the corresponding weight. When the three-axis micromachined gyroscope receives an angular velocity, the swinging weight is subjected to Coriolis force and a corresponding position change occurs.

Abstract: A modular structure may comprise multiple mechanical linkages. The structure may undergo two-dimensional or three-dimensional shape transformations, such as bending, twisting, shearing, uniform scaling, and anisotropic scaling. These shape transformations may be actuated by applying force to one or more specific locations in the structure. Each of the linkages in the modular structure may comprise a four-bar linkage. The exact shape transformation that the structure undergoes may be determined by the type and location of the linkages in the structure.

Abstract: The present disclosure discloses a two-layered varied ball diameter packed bed heat storage apparatus and a method of manufacturing a heat storage ball. By arranging large-diameter heat storage balls at an upper layer of a packed bed heat storage apparatus and small-diameter heat storage balls at a lower layer thereof; the packed bed heat storage structure comprehensively considers two important evaluation indicators for a heat storage apparatus: heat storage rate and heat storage density, thereby implementing a design principle of maximizing the heat storage rate density of the packed bed heat storage apparatus; by achieving a best combination of heat storage ball diameters inside the packed bed through an optimized design, the heat storage apparatus is imparted with a best heat storage performance. The present disclosure further provides a method of manufacturing a heat storage ball.

Abstract: A fabrication method for stretchable/conformable electronic and optoelectronic circuits and the resulting circuits. The method may utilize a variety of electronic materials including, but not limited to Silicon, GaAs, InSb, Pb Se, CdTe, organic semiconductors, metal oxide semiconductors and related alloys or hybrid combinations of the aforementioned materials. While a wide range of fabricated electronic/optoelectronic devices, circuits, and systems could be manufactured using the embodied technology, a hemispherical image sensor is an exemplary advantageous optoelectronic device that is enabled by this technology. Other applications include but are not limited to wearable electronics, flexible devices for the internet-of-things, and advanced imaging systems.

Abstract: The present inventions provides drug-drug conjugates, drug-porphyrin conjugates, nanoparticles of the conjugates, as well as modified nanoparticles having PEGylated exteriors or encapsulated by red blood cell vesicles. The conjugates, nanoparticles and nanocarriers are useful for treating cancers and other diseases, as well as for imaging diseased tissue or organs.

Abstract: An example multiply accumulate (MACC) circuit includes: a multiply-accumulator having an accumulator output register; a quantizer, coupled to the multiply accumulator; and a control circuit coupled to the multiply-accumulator and the quantizer, the control circuit configured to provide control data to the quantizer, the control data indicative of a most-significant bit (MSB) to least significant bit (LSB) range for selecting bit indices from the accumulator output register.

Abstract: A fabrication method for stretchable/conformable electronic and optoelectronic circuits and the resulting circuits. The method may utilize a variety of electronic materials including, but not limited to Silicon, GaAs, InSb, PbSe, CdTe, organic semiconductors, metal oxide semiconductors and related alloys or hybrid combinations of the aforementioned materials. While a wide range of fabricated electronic/optoelectronic devices, circuits, and systems could be manufactured using the embodied technology, a hemispherical image sensor is an exemplary advantageous optoelectronic device that is enabled by this technology. Other applications include but are not limited to wearable electronics, flexible devices for the internet-of-things, and advanced imaging systems.

Abstract: A modular structure may comprise multiple mechanical linkages. The structure may undergo two-dimensional or three-dimensional shape transformations, such as bending, twisting, shearing, uniform scaling, and anisotropic scaling. These shape transformations may be actuated by applying force to one or more specific locations in the structure. Each of the linkages in the modular structure may comprise a four-bar linkage. The exact shape transformation that the structure undergoes may be determined by the type and location of the linkages in the structure.

Abstract: Methods and apparatus relating generally to synthesis are described. In such a method, a directed graph for a circuit design is generated. A cascaded chain is identified in the directed graph with a timing violation. A pipeline register stage of the cascaded chain is moved (or added) to remove the timing violation. The circuit design is transformed to provide a netlist including the pipeline register stage.

Abstract: The present disclosure discloses a two-layered varied ball diameter packed bed heat storage apparatus and a method of manufacturing a heat storage ball. By arranging large-diameter heat storage balls at an upper layer of a packed bed heat storage apparatus and small-diameter heat storage balls at a lower layer thereof; the packed bed heat storage structure comprehensively considers two important evaluation indicators for a heat storage apparatus: heat storage rate and heat storage density, thereby implementing a design principle of maximizing the heat storage rate density of the packed bed heat storage apparatus; by achieving a best combination of heat storage ball diameters inside the packed bed through an optimized design, the heat storage apparatus is imparted with a best heat storage performance. The present disclosure further provides a method of manufacturing a heat storage ball.