Abstract: The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Abstract: In general, the instant invention comprises compounds of Formulas I and II including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful for treating cancer and other protein kinase mediated diseases.

Abstract: The present invention is directed to intermediates that are useful for preparing pyrrolotriazines, and processes for preparing such intermediates.

Abstract: The invention is directed to pyridinone compounds useful for modulating Met kinase, having the following structure: and is further directed to pharmaceutical compositions comprising the compound; and methods for treating proliferative diseases, such as cancer by the administration of this compound.

Abstract: In general, the instant invention comprises compounds having Formulae I and II: including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful for treating cancer and other protein kinase mediated diseases.

Abstract: The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Abstract: The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Abstract: Embodiments of the present invention disclose a communication system for implementing online file storage based on an instant messaging (IM) platform and a method thereof, the method includes: an IM client transmits an online storage operation request of a file to an online file storage access server; the online file storage access server interacts with the online file storage server to implement the online storage operation according to the online storage operation request, and returns the result of operation to the IM client. By using the communication system and method, a user can implement various online storage operations such as file storing, deleting, sharing, copying and the like via the existed IM client, without downloading a special online file storage client. The operation is simple, and functions and storing and reading speeds the same as the ones provided by the online storage in the special client-based mode can be achieved.

Abstract: In general, the instant invention comprises compounds having Formulae I and II: including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful for treating cancer and other protein kinase mediated diseases.

Abstract: The invention is directed to compounds that are useful for the treatment of cancer having the following Formula:

Abstract: In general, the instant invention comprises compounds of Formulas I and II including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful for treating cancer and other protein kinase mediated diseases.

Abstract: The coaxial dipole antenna of the present invention has a ground tube made of metal and a coaxial cable. The ground tube has a hollow containing part that the coaxial cable passes through, and an end of the ground tube has a clamping part. The clamping part has a first clamping slice to clamp a jacket of the coaxial antenna and a second clamping slice to clamp a metallic mesh of the coaxial cable. Such coaxial dipole antenna can transmit energy with the coaxial cable. The elements of the coaxial dipole antenna are combined with each other by pressing. Therefore, the coaxial dipole antenna can be manufactured by automation, the product thereof can be increased, and the quality thereof can be controlled.

Abstract: The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Abstract: The coaxial dipole antenna of the present invention has a ground tube made of metal and a coaxial cable. The ground tube has a hollow containing part that the coaxial cable passes through, and an end of the ground tube has a clamping part. The clamping part has a first clamping slice to clamp a jacket of the coaxial antenna and a second clamping slice to clamp a metallic mesh of the coaxial cable. Such coaxial dipole antenna can transmit energy with the coaxial cable. The elements of the coaxial dipole antenna are combined with each other by pressing. Therefore, the coaxial dipole antenna can be manufactured by automation, the product thereof can be increased, and the quality thereof can be controlled.

Abstract: The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Abstract: The present invention is directed to intermediates that are useful for preparing pyrrolotriazines, and processes for preparing such intermediates.

Abstract: In general, the instant invention comprises compounds of Formulas I and II including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful for treating cancer and other protein kinase mediated diseases.

Abstract: The compounds of the instant invention can be used as anticancer agents.