Abstract: The invention provides 3D-knitted spacer fabrics of high breathability and moisture management and methods of making the 3D-knitted spacer fabrics. The middle layer of the fabric is made of hydrophilic material, comprising two yarns, a blended thermo-fuse wicking yarn comprising hydrophilic fiber and thermo-fuse fiber, and a non-supportive hydrophilic functional wicking yarn. The top layer of the fabric comprises a hydrophilic yarn, and the third layer of the fabric comprises a hydrophobic yarn. The 3D-knitted spacer fabrics are useful in clothing and equipment for wear in high temperature environments.

Abstract: A pea-derived peptide with a muscle-building effect and a preparation method thereof, and a drug and use, are disclosed. A pea protein is subjected to enzymatic hydrolysis, and five polypeptides with muscle-building effect are obtained by separation as separate peptide fragments. In an in vitro aging skeletal muscle cell assay, changes are analyzed in a gene expression level of regulatory pathways related to skeletal muscle cell proliferation and differentiation, apoptosis and autophagy, and protein synthesis and degradation. In addition, animal experiments are conducted to study the muscle-building effect and a corresponding mechanism of the pea-derived peptide. This shows that the five polypeptide sequences have a significant muscle-building effect, usable as a polypeptide drug for the treatment of sarcopenia.

Abstract: The embodiment of the present disclosure discloses a method, an electronic device, and a storage medium for a ship route optimization. The method for the ship route optimization considers a dynamic feature of a multi-functional emergency rescue ship and an interference effect caused by an airflow, uses a movement model with kinematics non-holonomic constraints, such as a ship total cost assessment function to simulate the movement of the ship, and based on a sparrow search algorithm, learns how to apply the algorithm to a route plan of the emergency rescue ship. The method can improve the ship route optimization algorithm, improve an accuracy and practical applicability of a calculated plan. The method can effectively and accurately locate obstacles and hidden reefs, and consider effects of an airflow and a non-holonomic constraint effect, so as to make the route planning of the ship more efficient and intelligent.

Abstract: The invention discloses a method and a device for treating cyanobacteria in a water area based on the principle of biological competition, the method comprising: finding an area where cyanobacteria most easily accumulate, i.e. a concave bank of a water area, and setting up an algae interception net around the area; quickly and largely clearing the cyanobacteria in the area by means of manual or mechanical catching; planting emerged plants on the shoreline of the water area to fundamentally improve water quality; and additionally, densely arranging treatment tanks in a larger water area to kill the cyanobacteria gradually, and collecting dead cyanobacteria to prevent them from polluting the water area subsequently; and collecting and treating the tanks regularly for recycling.

Abstract: The invention provides triple crosslinked cooling hydrogel compositions of high tensile strength, high compressibility, high elasticity, and long cooling period and methods of making the compositions. The compositions are useful in clothing and equipment for wear in high solar radiation environments and high temperature environments.

Abstract: A compound serving as a thyroid hormone ? receptor agonist and uses of the compound, also provided is a pharmaceutical composition comprising the compound. The compound or the pharmaceutical composition is applicable in preparing a medicament for preventing, treating, or alleviating thyroid hormone ? receptor agonist-modulated diseases, and specifically applicable in preparing a medicament for treating nonalcoholic fatty liver disease.

Abstract: Embodiments of the systems, methods, and software provided herein patterns substrates using digital lithography patterning controlled by field programmable gate arrays (FPGA). Stage position data is provided to the FPGA from the lithography environment and the data is loaded into a memory from the FPGA. The graphics processing unit, reads the data from the memory and calculates instructions based on the data. At least a portion of a substrate disposed on the stage is processed using instructions provided by the FPGA.

Abstract: A method for preparing glucopyranosyl derivatives as sodium dependent glucose cotransporter (SGLT) inhibitors, an intermediate thereof, and a method for preparing the intermediate.

Abstract: Various embodiments are directed to safety device connector apparatuses for use with a wearable safety harness. A safety device connector apparatus may comprise a base portion operable to attach to a strap of the wearable safety harness, the base portion comprising a base attachment pin fixedly secured thereto; a connector element configured to be detachably coupled to the base portion via a connector element detachable base interface comprising a connector interface opening and configured to engage the base attachment pin, wherein engaging the base attachment pin comprises receiving the base attachment pin within the connector interface opening; wherein the connector interface opening comprises an angled notch configuration configured to facilitate a movement of the base attachment pin relative to the connector interface opening; and wherein the connector element is configured to detach from the base portion based at least in part on a load force acting on the connector element.

Abstract: At present relates to a glucopyranosyl derivative and application thereof. In particular, relates to a glucopyranosyl derivative as a sodium-dependent glucose transporters1 (SGLT1) inhibitor, and a pharmaceutically acceptable salt or a stereoisomer thereof, and further relates to a pharmaceutical composition containing the derivative.

Abstract: A relief apparatus and method of use for providing a flexible connection point between straps of a harness and mitigating suspension trauma for a user of the harness. In various embodiments, the relief apparatus comprises a base plate comprising one or more base strap slots and a central cavity defined by a cavity wall protruding out of a plane of the base plate, and an upper plate comprising one or more upper strap slots and an aperture configured to fit around the cavity wall of the base plate. The base plate and the upper plate are arrange concentrically along a central axis and may be configured to each rotate about the central axis. The relief apparatus further comprises a relief step comprised of a line and having a proximal end and a distal end, the distal end being secured to a deployment feature.

Abstract: Various embodiments are directed to relief apparatuses and methods of using the same. In various embodiments, a relief apparatus may comprise a housing comprising an interior housing portion configured to store a relief step device therein, and an activation assembly configured to facilitate an automated deployment of the relief step device from within the interior housing portion in response to a fall occurrence, wherein the automated deployment of the at least a portion of the relief step device is based at least in part on a load force acting on at least a portion of the activation assembly, wherein the load force is defined at least in part by a force generated as a result of the fall occurrence. In various embodiments, a relief apparatus may comprise an activation assembly that enables both an automated deployment and a manual deployment of a relief step device in a fall condition.

Abstract: Various embodiments are directed to backplates comprising a base portion attached to a strap of the wearable safety harness; and a connector element secured relative to the base portion and comprising a first safety device interface configured to engage a first safety device so as to couple the first safety device to the backplate. In various embodiments, the connector element is selectably detachable from the base portion. In various embodiments, the connector element comprises a second safety device interface configured to engage a second safety device so as to couple the second safety device to the backplate. In various embodiments, the connector element operably secures both the first safety device and the second safety device relative to the base portion. In various embodiments, the connector element operably secures a first safety device comprising a personal fall limitor and a second safety device comprising a D-ring relative to the base portion.

Abstract: A chemical compound as a thyroid hormone Beta receptor agonist and a use thereof, further including a pharmaceutical composition containing the chemical compound. The chemical compound or pharmaceutical composition can be used in the preparation of drugs for preventing, treating or mitigation of diseases mediated by agonistic thyroid hormone ? receptor, particularly for the preparation of drugs for treating non-alcoholic fatty liver diseases.

Abstract: Various embodiments illustrated herein disclose a full body harness that includes a connector. The connector includes a first plate and a second plate, where the first plate is identical to the second plate. The first plate and the second plate includes a plurality of slits to facilitate passage of a first harness and a second harness there through. The first plate is rotatably coupled to the second plate such that they are rotatable with respect to each other. Such a connector automatically enables easy adjustment of the harness based on an activity of a user who is wearing the harness.