Patents by Inventor Zheng Gu

Zheng Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240025875
    Abstract: A compound serving as a thyroid hormone ? receptor agonist and uses of the compound, also provided is a pharmaceutical composition comprising the compound. The compound or the pharmaceutical composition is applicable in preparing a medicament for preventing, treating, or alleviating thyroid hormone ? receptor agonist-modulated diseases, and specifically applicable in preparing a medicament for treating nonalcoholic fatty liver disease.
    Type: Application
    Filed: September 16, 2021
    Publication date: January 25, 2024
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng GU, Jianhao LI, Jianchao DENG, Yongxiang LI, Haoxiong QIN, Daoqian CHEN, Xiaomin ZHENG, Jianghong YU, Huantian ZHAO
  • Publication number: 20230259038
    Abstract: Embodiments of the systems, methods, and software provided herein patterns substrates using digital lithography patterning controlled by field programmable gate arrays (FPGA). Stage position data is provided to the FPGA from the lithography environment and the data is loaded into a memory from the FPGA. The graphics processing unit, reads the data from the memory and calculates instructions based on the data. At least a portion of a substrate disposed on the stage is processed using instructions provided by the FPGA.
    Type: Application
    Filed: July 29, 2020
    Publication date: August 17, 2023
    Inventors: Zheng GU, Yujiao HUANG, Deepthy M. GEORGE
  • Publication number: 20230250121
    Abstract: A method for preparing glucopyranosyl derivatives as sodium dependent glucose cotransporter (SGLT) inhibitors, an intermediate thereof, and a method for preparing the intermediate.
    Type: Application
    Filed: July 7, 2021
    Publication date: August 10, 2023
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng GU, Tong QU, Wuyong WU, Weiming HUANG, Daoqian CHEN, Zongyuan ZHANG, Haoxiong QIN, Zheng LI, Weihui YUAN, Shijie NIU, Fei PENG, Tianyun WU
  • Publication number: 20230094364
    Abstract: Various embodiments are directed to safety device connector apparatuses for use with a wearable safety harness. A safety device connector apparatus may comprise a base portion operable to attach to a strap of the wearable safety harness, the base portion comprising a base attachment pin fixedly secured thereto; a connector element configured to be detachably coupled to the base portion via a connector element detachable base interface comprising a connector interface opening and configured to engage the base attachment pin, wherein engaging the base attachment pin comprises receiving the base attachment pin within the connector interface opening; wherein the connector interface opening comprises an angled notch configuration configured to facilitate a movement of the base attachment pin relative to the connector interface opening; and wherein the connector element is configured to detach from the base portion based at least in part on a load force acting on the connector element.
    Type: Application
    Filed: September 13, 2022
    Publication date: March 30, 2023
    Inventors: Wenbo WANG, Peng ZHOU, Ling LIN, Zheng GU, Xiaojuan ZHU, Lyndon LIU
  • Publication number: 20230086354
    Abstract: At present relates to a glucopyranosyl derivative and application thereof. In particular, relates to a glucopyranosyl derivative as a sodium-dependent glucose transporters1 (SGLT1) inhibitor, and a pharmaceutically acceptable salt or a stereoisomer thereof, and further relates to a pharmaceutical composition containing the derivative.
    Type: Application
    Filed: July 9, 2020
    Publication date: March 23, 2023
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng GU, Wuyong WU, Panpan KANG, Weihua WANG, Jianyu LIU, Xinshan DENG
  • Publication number: 20230022288
    Abstract: A relief apparatus and method of use for providing a flexible connection point between straps of a harness and mitigating suspension trauma for a user of the harness. In various embodiments, the relief apparatus comprises a base plate comprising one or more base strap slots and a central cavity defined by a cavity wall protruding out of a plane of the base plate, and an upper plate comprising one or more upper strap slots and an aperture configured to fit around the cavity wall of the base plate. The base plate and the upper plate are arrange concentrically along a central axis and may be configured to each rotate about the central axis. The relief apparatus further comprises a relief step comprised of a line and having a proximal end and a distal end, the distal end being secured to a deployment feature.
    Type: Application
    Filed: July 7, 2022
    Publication date: January 26, 2023
    Inventors: Xiaojuan ZHU, Peng ZHOU, Ling LIN, Zheng GU, Wenbo WANG, Lyndon LIU
  • Publication number: 20230026773
    Abstract: Various embodiments are directed to backplates comprising a base portion attached to a strap of the wearable safety harness; and a connector element secured relative to the base portion and comprising a first safety device interface configured to engage a first safety device so as to couple the first safety device to the backplate. In various embodiments, the connector element is selectably detachable from the base portion. In various embodiments, the connector element comprises a second safety device interface configured to engage a second safety device so as to couple the second safety device to the backplate. In various embodiments, the connector element operably secures both the first safety device and the second safety device relative to the base portion. In various embodiments, the connector element operably secures a first safety device comprising a personal fall limitor and a second safety device comprising a D-ring relative to the base portion.
    Type: Application
    Filed: August 31, 2021
    Publication date: January 26, 2023
    Inventors: Wenbo WANG, Ling LIN, Xiaojuan ZHU, Zheng GU, Lyndon LIU, Peng ZHOU
  • Publication number: 20230025031
    Abstract: Various embodiments are directed to relief apparatuses and methods of using the same. In various embodiments, a relief apparatus may comprise a housing comprising an interior housing portion configured to store a relief step device therein, and an activation assembly configured to facilitate an automated deployment of the relief step device from within the interior housing portion in response to a fall occurrence, wherein the automated deployment of the at least a portion of the relief step device is based at least in part on a load force acting on at least a portion of the activation assembly, wherein the load force is defined at least in part by a force generated as a result of the fall occurrence. In various embodiments, a relief apparatus may comprise an activation assembly that enables both an automated deployment and a manual deployment of a relief step device in a fall condition.
    Type: Application
    Filed: August 31, 2021
    Publication date: January 26, 2023
    Inventors: Wenbo WANG, Ling LIN, Xiaojuan ZHU, Zheng GU, Lyndon LIU, Zhou WEIMING, Peng ZHOU
  • Publication number: 20220411400
    Abstract: A chemical compound as a thyroid hormone Beta receptor agonist and a use thereof, further including a pharmaceutical composition containing the chemical compound. The chemical compound or pharmaceutical composition can be used in the preparation of drugs for preventing, treating or mitigation of diseases mediated by agonistic thyroid hormone ? receptor, particularly for the preparation of drugs for treating non-alcoholic fatty liver diseases.
    Type: Application
    Filed: September 23, 2020
    Publication date: December 29, 2022
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng GU, Jianhao LI, Xinshan DENG, Zheng LI, Daoqian CHEN, Jianchao DENG, Aizhen LV, Jianyu LIU
  • Publication number: 20220314043
    Abstract: Various embodiments illustrated herein disclose a full body harness that includes a connector. The connector includes a first plate and a second plate, where the first plate is identical to the second plate. The first plate and the second plate includes a plurality of slits to facilitate passage of a first harness and a second harness there through. The first plate is rotatably coupled to the second plate such that they are rotatable with respect to each other. Such a connector automatically enables easy adjustment of the harness based on an activity of a user who is wearing the harness.
    Type: Application
    Filed: May 14, 2021
    Publication date: October 6, 2022
    Inventors: Ling LIN, Lyndon LIU, Peng ZHOU, Pinghua JIANG, Wenbo WANG, Zheng GU, Xiaojuan ZHU
  • Publication number: 20220315536
    Abstract: An isoquinolinone compound acts as an inhibitor of semicarbazide-sensitive oxidase (SSAO) and/or vascular adhesion protein-1 (VAP-1), and the use thereof, and further relates to a pharmaceutical composition containing the compound. The compound or the pharmaceutical composition can be used to prepare a drug for preventing, treating or ameliorating inflammation and/or inflammation-related diseases, diabetes and/or diabetes-related diseases in patients, and especially can be used to prepare a drug for preventing, treating or ameliorating non-alcoholic fatty liver diseases in patients.
    Type: Application
    Filed: May 20, 2020
    Publication date: October 6, 2022
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng GU, Jianhao LI, Weihua WANG, Haoxiong QIN, Xinshan DENG
  • Publication number: 20220267346
    Abstract: Thienopyrimidine derivative having stereo configurations and use thereof in medicine. Also included are pharmaceutical compositions of the compounds. The compounds or pharmaceutical compositions may be used to inhibit acetyl-CoA carboxylase (ACC). A method for preparing the compounds and the pharmaceutical compositions, and use thereof in treatment or prevention of diseases associated with ACC regulation of mammals, in particular, humans.
    Type: Application
    Filed: July 2, 2019
    Publication date: August 25, 2022
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng GU, Wanjun TANG, Xinye YANG, Xuli WANG, Weihui YUAN, Yunzeng CUI, Wen YANG, Jianyu LIU, Yingjun ZHANG
  • Patent number: 11396495
    Abstract: An amine compound serving as a semicarbazide-sensitive amine oxidase (SSAO) and/or vascular adhesion protein-1 (VAP-1) inhibitor, a pharmaceutical composition, and an application thereof in medicines that can be used for treating inflammation and/or inflammation related diseases, diabetes and/or a disease related diabetes, psychiatric disorder, ischemic disease, vascular disease, fibrosis, or tissue transplant rejection.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: July 26, 2022
    Assignee: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng Gu, Jianhao Li, Zheng Li, Weihua Wang, Haoxiong Qin, Xuli Wang, Jianyu Liu, Yingjun Zhang
  • Publication number: 20220083011
    Abstract: A bipolar TDC apparatus with a phase detection and signal switching circuitry and a phase error measurement circuitry. The phase detection and signal switching circuitry include a multiplexer and phase detector, together referred to as PD_MUX. The PD_MUX is used to handle the order of the two input signal phases of a TDC, or in other words, to enable TDC the bipolarity detection of the phase error. The apparatus detects first the polarity of the phase error and then prepares the right phase order when they arrive at the TDC measurement elements of the phase error measurement circuitry to ensure that always the earlier one starts the TDC and the later one triggers the measurement event. As such, the phase measurement circuitry (or measurement block) provides the phase error magnitude information, while the PD_MUX provides the sign—polarity information.
    Type: Application
    Filed: September 15, 2020
    Publication date: March 17, 2022
    Applicant: Intel Corporation
    Inventor: Zheng Gu
  • Patent number: 11186602
    Abstract: A glucopyranosyl derivative is used as an inhibitor of sodium-dependent glucose transporters (SGLTs), particularly being used as an inhibitor of sodium-dependent glucose transporter-1 (SGLT1), and a pharmaceutically acceptable salt or stereoisomer thereof, further relating to a pharmaceutical composition containing the derivative. The compound and a pharmaceutical composition is used thereof in the preparation of a drug for treating diabetes and diabetes-related diseases.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: November 30, 2021
    Assignee: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng Gu, Wuyong Wu, Panpan Kang, Tong Qu, Zongyuan Zhang, Weiming Huang, Tianyun Wu, Yingjun Zhang
  • Patent number: 11084842
    Abstract: A glucopyranosyl derivative as a sodium-dependent glucose transporters inhibitor, especially as a SGLT1 inhibitor, a pharmaceutically acceptable salt or a stereoisomer thereof, a pharmaceutical composition thereof, and the uses of the compound and pharmaceutical composition thereof in the preparation of drugs for the treatment of diabetes and diabetes-related diseases.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: August 10, 2021
    Assignee: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng Gu, Wuyong Wu, Tong Qu, Panpan Kang, Zongyuan Zhang, Weiming Huang, Jianyu Liu, Yingjun Zhang
  • Patent number: 11067905
    Abstract: Embodiments of the systems and methods discussed herein autofocus an imaging apparatus by pre-processing image data received via channels of the imaging system that include laser beams and sensors configured to receive image data when laser beams are applied across a substrate in a pixel-wise application across a substrate. The substrate can include both a photoresist and metallic material, and the images as-received by the sensors include noise from the metallic material. During pre-processing of the image data, a percentage of noise to remove from the image data is determined, and the image data is filtered. A centroid of the substrate is calculated for each channel and a focus deviation for the exposure is determined. The centroids can be combined using one or more filtering mechanisms, and the imaging system can be autofocused in an exposure position by moving the stage and/or the exposure source in one or more directions.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: July 20, 2021
    Assignee: APPLIED MATERIALS, INC.
    Inventors: Diana Valverde-Paniagua, Zhongchuan Zhang, Rendong Lin, Zheng Gu, Meenaradchagan Vishnu, Glen Alan Gomes
  • Publication number: 20210216023
    Abstract: Embodiments of the systems and methods discussed herein autofocus an imaging apparatus by pre-processing image data received via channels of the imaging system that include laser beams and sensors configured to receive image data when laser beams are applied across a substrate in a pixel-wise application across a substrate. The substrate can comprise both a photoresist and metallic material, and the images as-received by the sensors include noise from the metallic material. During pre-processing of the image data, a percentage of noise to remove from the image data is determined, and the image data is filtered. A centroid of the substrate is calculated for each channel and a focus deviation for the exposure is determined. The centroids can be combined using one or more filtering mechanisms, and the imaging system can be autofocused in an exposure position by moving the stage and/or the exposure source in one or more directions.
    Type: Application
    Filed: April 9, 2019
    Publication date: July 15, 2021
    Inventors: Diana VALVERDE-PANIAGUA, Zhongchuan ZHANG, Rendong LIN, Zheng GU, Meenaradchagan VISHNU, Glen Alan GOMES
  • Patent number: D990787
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: June 27, 2023
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Zheng Gu, Peng Zhou, Wenbo Wang, Xiaojuan Zhu, Ling Lin, Lyndon Liu, Zhao Xia Jin, Tiecheng Qu, Weiming Zhou, Yolanda Wang
  • Patent number: D1005174
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: November 21, 2023
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Zheng Gu, Peng Zhou, Wenbo Wang, Xiaojuan Zhu, Ling Lin