Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO844, PRO1131 or PRO5992 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.

Abstract: The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.

Abstract: The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.

Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO188, PRO235, PRO266, PRO337, PRO361, PRO539, PRO698, PRO717, PRO846, PRO874, PRO98346, PRO1082, PRO1097, PRO1192, PRO1268, PRO1278, PRO1303, PRO1308, PRO1338, PRO1378, PRO1415, PRO1867, PRO1890, PRO3438, PRO19835, PRO36915, PRO36029, PRO4999, PRO5778, PRO5997, PRO6079, PRO6090, PRO7178, PRO21184, PRO7434, PRO9822, PRO9833, PRO9836, PRO9854, PRO9862, PRO10284, PRO37510, PRO35444, PRO20473, PRO21054 or PRO35246 genes.

Abstract: A keypad assembly (15) applied to a portable electronic device and mounted in a shell of the portable electronic device is provided. The keypad assembly comprises a keypad cover (151) and a printed circuit board (152). The keypad cover is provided with at least one contact portion (1516) thereon. The printed circuit board provided with a plurality of signal-sensing portions (1522) thereon. The shell is provided with at least one guide hole (116) corresponding to the plurality of signal-sensing portions. The shell is configured between the keypad cover and the printed circuit board, and the keypad cover is rotatably mounted in the shell. The signal-sensing portion is pressed by the contact portion through the guide hole. A portable electronic device using the keypad assembly is also disclosed.

Abstract: A keypad assembly (10) for use in a portable electronic device (8), includes a housing (14) and a key (12). The housing is substantially a flat board, and defines a recess and a hole (143, 145) therein. The key is mounted in the recess and the hole and is defined as in an original state when it is not operated. The key is capable of moving in different directions relative to the housing when it is manually operated. The key is defined as in an operational state when it is manually moved.

Abstract: A keypad assembly (10) for use in a portable electronic device (8), includes a housing (14) and a key (12). The housing is substantially a flat board, and defines a recess and a hole (143, 145) therein. The key is mounted in the recess and the hole and is defined as in an original state when it is not operated. The key is capable of moving in different directions relative to the housing when it is manually operated. The key is defined as in an operational state when it is manually moved.

Abstract: A mounting apparatus for a storage device includes a bracket for receiving the storage device and a base for mounting the bracket therein. A fixing portion including two sidewalls is formed on the base. A hooking recess is defined in one of the sidewalls of the fixing portion. A sliding member is received in the fixing portion for fixing the bracket, and the sliding member includes a hook to engage in the hooking recess of the fixing portion. An elastic member is received in the fixing portion for restoring the sliding member.

Abstract: A side key assembly is mounted on a housing (60) which comprises a sidewall (610). A socket (62) is formed in the sidewall (610) of the housing. The side key assembly includes a button (70), two switches (80) and the socket. The button includes an operating portion (710), two touching blocks (740) and at least one elastic arm (750). The operating portion is slidingly received in the socket. One end of the at least one elastic arm connects with the operating portion while the other end is firmly fixed on the housing. Each switch includes a contact portion. Each contact portion is positioned adjacent to a corresponding touching block. Each switch is turned on when the corresponding touching block is moved to touch the contact portion thereof.

Abstract: A keypad assembly used in a portable electronic device (100) includes at least one key button (40) and at least one fixing member (30). Each key button is slidingly received in a receiving hole (26) defined in a cover (20) of the portable electronic device. The at least one fixing member is fixed on the cover. Each fixing member includes at least one latching portion (31) and a plurality of curved portions (32). Each latching portion connects with the curved/bias portions. Each latching portion firmly connects with at least one key button. The corresponding latching portion of the fixing member is configured for selectably pressing into a chosen switch (12) in the portable electronic device, so as to form/prompt an electronic signal when the key button is given an appropriate horizontal force to initiate such contact with a given switch.

Abstract: A portable electronic device (40) includes a housing (41), a display section (42) formed on the housing, and a stylus (20) connected to the housing. The display section has a screen. The stylus includes a writing portion (21), a sleeve (23), and a holder (25) formed on the sleeve. The writing portion is for moving on the screen of the display section. The sleeve has a first end (231) connecting with the writing portion, and an opposite second end being open.

Abstract: One aspect of the present invention relates to a slider having a slider body. The slider body includes a bearing surface defining a bearing surface plane, a leading edge, a trailing edge, first side edge, a second side edge and at least one corner. A corner feature is positioned proximate the at least one corner. The corner feature includes a first portion oriented in a first direction and a second portion oriented in a second direction that is different then the first direction. At least one of the first direction and the second direction is toward the trailing edge and is oblique to the bearing surface plane.

Abstract: A fixing mechanism includes a receptacle for receiving a component. A pair of spaced rails is formed in the receptacle and defining a slideway therebetween. A latch member is movable along the slideway. A resilient member is installed adjacent the slideway and engagable with the latch member to urge the latch member forward for fixing the component and to assist in urging the latch member backward when the latch member is operated to unfix the component.