Abstract: Systems, methods, and analytical approaches for short read sequence assembly and for the detection of insertions and deletions (indels) in a reference genome. A method suitable for software implementation is presented in which indels may be readily identified in a computationally efficient manner.

Abstract: Analyzing and detecting soft hang program errors may lead to suggestions for either curing the programming errors at runtime or refactoring the source code. For instance, responsive function invocation patterns and blocking function invocation patterns may be used to detect soft hang program errors in a source code file. Deductive database rules may be compiled from the responsive and blocking function invocation patterns to find matching function invocations in a call graph.

Abstract: A computing device includes a touch screen displaying a graphical user interface (GUI) and a processing unit programmed to recognize gestures made on the touch screen and execute, in response thereto, a process associated with the gestures.

Abstract: The present invention provides the multifunctional biological and biochemical sensor technology based on the integration of ZnO nanotips with bulk acoustic wave (BAW) devices, particularly, quartz crystal microbalance (QCM) and thin film bulk acoustic wave resonator (TFBAR). ZnO nanotips provide giant effective surface area and strong bonding sites. Furthermore, the controllable wettability of ZnO nanostructured surface dramatically reduces the liquid consumption and enhances the sensitivity of the biosensor device.

Abstract: A hinge mechanism includes two pivot shafts substantially parallel to each other, two main gears non-rotatably respectively sleeved on the pivot shafts, a transmission assembly positioned between the two pivot shafts to transmit a torque of one of the two main gears to the other in a reverse direction, and a connecting member defining two shaft holes. The pivot shafts are respectively rotatably received in the shaft holes. Two contact assemblies are respectively mounted on the pivot shafts abutting the connecting member. One of the connecting member and each main gear forms at least one detent, and the other defines at least one recess correspondingly. The at least one detent is received in the at least one recess.

Abstract: Predicate checking in conjunction with distributed systems can enable an investigating user to check predicates in the context of instance states and/or distributed states of a distributed system. In an example embodiment, a method entails accepting distributed system simulation data and performing a simulation of a distributed system using the distributed system simulation data to create distributed system simulated states. At least a portion of the distributed system simulated states are exposed. The exposed portion of the distributed system simulated states is retrieved and stored as exposed states for the distributed system. The exposed states for the distributed system are compared to predicate states for the distributed system. If an inconsistency is detected between the exposed states and the predicate states based on the comparing, at least one alarm is issued.

Abstract: Collection-based object replication for a system that includes a client computing device (client) connected to a server and multiple data storage nodes. In certain cases, a data storage node generates a replica of multiple replicas of a collection. The collection is a unit of data placement, access, replication, and repair. Other data storage nodes are also configured with a respective replica of the multiple replicas. The data storage node verifies whether an object received directly from the client for storage in the collection has been fully replicated by the other data storage nodes in respective replicas.

Abstract: A hinge assembly includes a first pivot shaft, a second pivot shaft, a third pivot shaft, a first bracket, a second bracket, a first meshing wheel, a second meshing wheel, a third meshing wheel, and a transmission belt member sleeved on both the first meshing wheel and the third meshing wheel. The first pivot shaft, the second pivot shaft, and the third pivot shaft are substantially parallel. The first and second brackets are non-rotatably sleeved on the first and second pivot shafts, respectively. The third meshing wheel is disposed between the first meshing wheel and the second meshing wheel, and meshes with the second meshing wheel and the transmission belt member. An electronic device using the hinge assembly is also provided.

Abstract: Techniques and systems for providing optimization of traffic routing for data centers are disclosed herein. In some embodiments, a method may include identifying a plurality of available source sites and paths or routes between an online service provider (OSP) and a destination prefix. A traffic manager may measure a cost for each of the plurality of available paths. In some instances, the traffic manager may also measure a performance value for each of the available paths. The traffic manager may then select one of the available source sites and paths as a preferred source site and path that has a minimized cost for an instance of the performance value when compared to other paths of the plurality of available source sites and paths. In further embodiments, the traffic manager may rewrite a routing table and DNS mapping to implement the preferred source site and path as the default source site and path between the OSP and the destination prefix.

Abstract: A computer-implemented method for classifying alignments of paired nucleic acid sequence reads is disclosed. A plurality of paired nucleic acid sequence reads is received, wherein each read is comprised of a first tag and a second tag separated by an insert region. Potential alignments for the first and second tags of each read to a reference sequence is determined, wherein the potential alignments satisfies a minimum threshold mismatch constraint. Potential paired alignments of the first and second tags of each read are identified, wherein a distance between the first and second tags of each potential paired alignment is within an estimated insert size range. An alignment score is calculated for each potential paired alignment based on a distance between the first and second tags and a total number of mismatches for each tag.

Abstract: A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm2 in a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37° C. in 70 ?g/mL fibrinogen derived from human plasma containing 1.4 ?g/mL I-125 radiolabeled fibrinogen.

Abstract: The present invention discloses hydrocarbylidene nitrohydrozinecarboximidamides and the use thereof as well as a method for making the same. The structural general formula of the compounds are shown in formula I, wherein, R1 is C1-C10 saturated and/or unsaturated aliphatic hydrocarbonyl, benzyl, substituted benzyl, halogenated picolyl, halogenated thiazolyl methyl, tetrahydrofuryl methyl or oxazolyl methyl; R2 is hydrogen, C1-C5 saturated and/or unsaturated aliphatic hydrocarbonyl, phenyl, substituted phenyl, pyridyl or substituted pyridyl; R3 is hydrogen, C1-C10 saturated and/or unsaturated aliphatic hydrocarbonyl, furyl, phenyl, substituted phenyl, benzyl or substituted benzyl. The tests of insecticidal activity show that the hydrocarbylidene nitrohydrozinecarboximidamides shown by formula (I) have high preventive efficiency against insect pests of plants, such as aphid, plant hopper, cotton bollworm, asparagus caterpillar, and the like, and can be used as plant insecticides.

Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve coating the substrate to conceal or reduce flaws on or in the surface of the medical device or other article substrate, and thereafter forming a grafted polymer layer on the treated substrate surface.

Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface.

Abstract: The present invention generally relates to articles of manufacture, such as medical devices, having a non-fouling surface comprising a grafted polymer material. The surface resists the adhesion of biological material.

Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface.

Abstract: A post-crosslinked adsorbent comprises: monomer units of (a) at least 55 wt % at least one polyvinylaromatic monomer and (b) up to 45 wt % at least one monovinylaromatic monomer; and 0.5-2.5 mmol/g pendent vinyl groups; wherein the dry adsorbent has BET specific surface area in the range of about 650-1000 m2/g, BET average pore diameter 7.2-10 nm, BET porosity 1.29-2.45 mL/g, BJH adsorption micropore volume was less than 20% of total BJH adsorption pore volume, and HK micropore volume was less than 21% of total BJH adsorption pore volume. The invention is also directed to a preparation method for the polymeric adsorbent.

Abstract: A hinge mechanism includes a first rotation assembly, a second rotation assembly substantially parallel to the first rotation assembly, a first connection member, and a second connection member. The first and second rotation assemblies include a first and second pivoting shafts and a first and second brackets sleeved on the first and second pivoting shafts, respectively, and both the first and second brackets includes an engaging portion eccentrically formed on one end respectively thereof. The first connection member includes two pivotal portions. The pivotal portions are rotatably connected to the engaging portions of the first bracket and the second bracket, respectively. The second connection member is sleeved on the first pivoting shaft and the second pivoting shaft.

Abstract: Super-low fouling sulfobetaine and carboxybetaine materials, super-low fouling surfaces and methods of making the surfaces coated with sulfobetaine and carboxybetaine materials, and devices having the super-low fouling surfaces.

Abstract: A hinge mechanism includes two pivoting shafts substantially parallel to each other, two main gears non-rotatably sleeved on the pivoting shafts, respectively. The hinge mechanism further includes two transmission gears positioned between the main gears, and two brackets sleeved on the pivoting shafts, respectively. Each transmission gear meshes with the other transmission gear and one main gear. Each pivoting shaft includes a flange which defines two locking portions, and each bracket forms two latching portions engaging with the locking portions of each pivoting shaft. The locking portions and the latching portions are selected from the structures of groove and hook.