Abstract: Disclosed are compounds compound of Formula (I): Each variable is defined herein. Also included are pharmaceutical compositions containing such a compound and a method of treating an inflammatory condition.

Abstract: Disclosed herein is a pharmaceutical composition comprising a pharmaceutically effective amount of a neuroactive steroid that is a positive modulator of ? aminobutyric acid type A (GABAA) receptors. Also disclosed are methods of treating diseases using the pharmaceutical composition and processes of producing the pharmaceutical composition.

Abstract: The present invention is directed to methods for treating macular degeneration, atherosclerosis, fatty liver, obesity, and cognitive ability, and more specifically to methods for treating macular degeneration, atherosclerosis, fatty liver, obesity, and cognitive ability using very long chain polyunsaturated fatty acids having 24 to 40 carbon atoms.

Abstract: The disclosure provides a virtual prop control method and apparatus, a storage medium, and an electronic device. The method includes displaying a target virtual throw prop controlled by a first virtual operation object in a target game application. The method also includes controlling the throwing of the target virtual throw prop based on a target throw operation. The method also includes setting a target region at which the virtual throw prop is thrown as a damage detection region, with the damage detection region configured to reduce hit points of at least one target virtual operation object located in the damage detection region. Based on a second virtual operation object being included in the at least one target virtual operation object and entering the target region, the method also includes reducing hit points of the second virtual operation object.

Abstract: A proactive switchover process in a distributed database system evaluates available resources for a plurality of database instances based on database performance metrics of the database instances and resource metrics for physical hosts of the database instances. Periodic collection and storing of the metrics dataset provide for estimating a switching time length required for switching a primary database instance candidate with the current primary database instance. Further estimating based on historic values informs the proactive switchover determination.

Abstract: Provided herein are methods for administering a hepatitis B virus surface antigen (HBsAg) to subjects with chronic hepatitis B to distinguish between responder subjects who respond to the HBsAg administration with an increase in an HBV antibody levels and non-responder subjects, and treating chronic hepatitis B in the responder subjects with an HBV therapy. Methods of excluding non-responder subjects from a clinical study are also provided.

Abstract: An optical lens module includes an adjustable aperture assembly including rotatable blades, a driving part and an attractive force mechanism. The rotatable blades surround an optical axis of a lens element and form a light pass aperture. The driving part includes a rotatable component, a fixed component, a driving magnet and a coil. The rotatable component rotates the rotatable blades for adjusting an aperture size of the light pass aperture. The driving magnet is disposed on the rotatable component. The coil corresponds to the driving magnet to rotate the rotatable component. The attractive force mechanism provides an attractive force between the rotatable component and the fixed component and provides a driving force exerted on the rotatable blades for maintaining the light pass aperture in an enlarged state. The attractive force includes a magnetic force exerted by the rotatable component on a first magnetic element fixed on the fixed component.

Abstract: The present disclosure is directed to methods of treating or preventing RNA virus infections and retroviral diseases, such as HIV and AIDS, comprising administering to a subject in need an effective amount of (a) a capsid inhibitor and (b) an adenosine derivative disclosed herein. Compositions comprising an effective amount of an adenosine derivative and an effective amount of a capsid (CA) inhibitor are also provided.

Abstract: An X-ray device including a sensing panel and a scintillator layer is provided. The sensing panel includes a substrate and a first pixel. The first pixel is disposed on the substrate and includes a first light sensing component and a first switch component. The first switch component is disposed on the first light sensing component. The scintillator layer is disposed on the sensing panel, and the first switch component is disposed between the scintillator layer and the first light sensing component.

Abstract: A container for receiving a semiconductor device is provided. In one embodiment, the wafer holder assembly includes a first wafer holder with a plurality of first fingers arranged in a first common horizontal plane and a second wafer holder with a plurality of second fingers arranged in a second common horizontal plane. The first wafer holder and the second holder are configured to move relative to each other in a vertical direction, and the first wafer holder and the second holder are configured to rotate relative to each other around a vertical axis.

Abstract: A method for controlling a virtual object and a related apparatus are provided. The method includes displaying a user interface (UI) having a virtual environment image and an interactive panel region. The virtual environment image is an image in which a virtual environment is observed. The method also includes receiving a preset operation in a target region in the UI, with the target region being a region associated with the virtual environment image but not with the interactive panel region; and controlling the virtual object according to the preset operation to perform a corresponding motion in the virtual environment.

Abstract: An adjustable aperture module includes a blade assembly, a fixed component connected to the blade assembly, a movable component connected to the blade assembly, and a driving mechanism. The blade assembly includes light-blocking blades overlapping one another in a circumferential direction surrounding a central axis and together forming a light pass aperture. The movable component is disposed corresponding to the fixed component. The driving mechanism is configured to rotate the movable component in the circumferential direction relative to the fixed component. The driving mechanism includes at least one coil assembly and at least one magnet arranged along the circumferential direction. The coil assembly includes at least two coils. The magnet is disposed on the movable component and includes at least one magnetic pole. The magnetic pole is disposed corresponding to the coil assembly and facing at least two coils of the coil assembly.

Abstract: A lighting device (10) comprises an elongate arrangement of LEDs (14) with outer rows (r1, r2) of LEDs extending along the length direction, and at least one inner row (r3) of LEDs between the outer rows (r1, r2) of LEDs. The pitch (p1) of the LEDs of the inner row (r3) is greater than the pitch (p2) of the LEDs along the first and second outer rows (r1, r2). Thus, the spottiness of the outer rows (r1, r2) is reduced by having a smaller pitch.

Abstract: A method and an apparatus includes prompting that a virtual object is attacked. The method includes: displaying a user interface (UI) including a target virtual object located in a virtual environment. A being-attacked direction of the target virtual object is obtained. A display position of the being-attacked direction prompt information is obtained according to the being-attacked direction. The being-attacked direction prompt information is used for indicating the being-attacked direction. The being-attacked direction prompt information is displayed in the UI according to the display position. The being-attacked direction is prompted, and content of the being-attacked prompt is diversified.

Abstract: A virtual object control method includes displaying a user interface (UI) that includes a first fire button being an operation control configured to trigger to aim down sights (ADS) and fire. When a trigger signal corresponding to the first fire button is received, a virtual firearm enters an ADS state. When a fire condition is satisfied and the virtual firearm is in the ADS state, the virtual firearm can shoot. A one-tap ADS and fire capability is implemented which improves operation efficiency.

Abstract: An apparatus and method are described for graphics virtualization with late synchronization. For example, a virtualized graphics execution environment is implemented on a host, including a hypervisor to virtualize graphics processing resources for one or more virtual machines (VMs). A plurality of graphics commands are received responsive to execution of a graphics application in one of the VMs. The graphics commands are persisted until a frame triggering event is detected. Upon detection of a frame triggering event, the persisted graphics commands are submitted to the host.

Abstract: A wiring substrate includes a first insulating layer with a first opening, a second insulating layer with a second opening, a high-frequency wiring layer, a first wiring layer, a second wiring layer, and a plurality of conductive pillars. The high-frequency wiring layer including a high-frequency trace is sandwiched between the first insulating layer and the second insulating layer. The first opening and the second opening expose two sides of the high-frequency trace respectively. The high-frequency trace has a smooth surface which is not covered by the first insulating layer and the second insulating layer and has the roughness ranging between 0.1 and 2 ?m. The first insulating layer and the second insulating layer are all located between the first wiring layer and the second wiring layer. The conductive pillars are disposed in the second insulating layer and connected to the high-frequency trace.

Abstract: The invention provides a lighting device (1200) comprising (i) a light generating device (100), (ii) an air ionizer device (500), (iii) an airflow device (600), and a front part (750), wherein: (A) the lighting device (1200) comprises one or more first openings (710) and one or more second openings (720); wherein the front part (750) comprises the one or more second openings (720); (B) wherein the light generating device (100) is configured to generate device light (101); wherein the front part (750) comprises a first optical diffusor element (1151), wherein the light generating device (100) is configured upstream of the first optical diffusor element (1151), and wherein the first optical diffusor element (1151) is configured to transmit at least part of the device light (101); (C) the air ionizer device (500) is configured to generate in an operational mode charged particles at an electrode (1510); and (D) the airflow device (600) is configured to generate in the operational mode an airflow (1610) entraining

Abstract: Disclosed are compounds compound of Formula (I): Each variable is defined herein. Also included are pharmaceutical compositions containing such a compound and a method of treating an inflammatory condition.

Abstract: The invention provides a device (1200) comprising (i) a light generating device (100), (ii) an air ionizer device (500), and (iii) an airflow device (600), wherein: (A) the device (1200) comprises one or more first openings (710) and a front part (750) comprising one or more second openings (720); (B) the air ionizer device (500) is configured to generate in an operational mode positively charged particles at a first electrode (510) and negatively charged particles at a second electrode (520); (C) the airflow device (600) is configured to generate in the operational mode a first airflow (610) entraining the positively charged particles and a second airflow (620) entraining the negatively charged particles; wherein the one or more first openings (710) are configured upstream of the airflow device (600) and the electrodes (510,520); wherein a first part (721) of the one or more second openings (720) is configured downstream of the airflow device (600) and the first electrode (510), and a second part (722) of th