Patents by Inventor Zhi Hong

Zhi Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleoside analogs with carboxamidine modified monocyclic base
    Patent number: 7638496
    Abstract: Novel nucleoside analog compounds are disclosed. The novel compounds or pharmaceutically acceptable esters or salts thereof may be used in pharmaceutical compositions, and such compositions may be used to treat an infection, an infestation, a neoplasm, or an autoimmune disease. The novel compounds may also be used to modulate aspects of the immune system, including modulation of Type 1 and Type 2 activity.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: December 29, 2009
    Assignee: Valeant Pharmaceuticals North America
    Inventors: Robert Tam, Kandasamy Ramasamy, Zhi Hong, Johnson Lau
  • 4-CYANOPHENYLAMINO-SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INHIBITORS
    Publication number: 20090281124
    Abstract: This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.
    Type: Application
    Filed: July 16, 2009
    Publication date: November 12, 2009
    Applicant: Ardea Biosciences
    Inventors: Jean-Luc Girardet, Zhi Hong, Stephanie Shaw, Yung-hyo Koh
  • Use of vanillyl alcohol for the treatment of Parkinson's disease
    Publication number: 20090258951
    Abstract: A use of Vanillyl alcohol for treatment of Parkinson's disease is disclosed in accordance with the present invention. The Vanillyl alcohol's formula is 4-hydroxy-3-methoxy-benzyl alcohol and similitude with the human neurotransmitter dopamine. The Vanillyl alcohol has dopamine receptor stimulant and which is applied for pharmaceutical preparation of treating Parkinson's disease.
    Type: Application
    Filed: July 3, 2008
    Publication date: October 15, 2009
    Applicant: Red Pharma & Biotech Research Corporation
    Inventors: Lun-Chung Hsu, Zhi-Hong Wen, Kuan-Yu Lee
  • Substituted thieno[3,2-D]pyrimidines as HIV inhibitors
    Patent number: 7595324
    Abstract: This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.
    Type: Grant
    Filed: November 9, 2007
    Date of Patent: September 29, 2009
    Assignee: Ardea Biosciences, Inc.
    Inventors: Jean-Luc Girardet, Zhi Hong, Stephanie Shaw, Yung-hyo Koh
  • TIME SYNCHRONIZATION METHOD, TIME SYNCHRONIZATION EQUIPMENT AND NETWORK COMMUNICATION SYSTEM
    Publication number: 20090238214
    Abstract: A time synchronization method includes the following steps. First, network communication equipment receives time information sent by at least two time servers respectively, in which the time information includes time synchronization status information of each of the time servers. Then, it is determined whether time synchronization status of each of the time servers is normal or not according to the time synchronization status information. Finally, the network communication equipment selects to employ the time information provided by the time servers with the normal time synchronization status from the at least two time servers. Network communication equipment and a network communication system are also provided correspondingly.
    Type: Application
    Filed: May 21, 2009
    Publication date: September 24, 2009
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventor: Zhi HONG
  • Electrical connector having grounding bridge
    Publication number: 20090227129
    Abstract: An electrical connector includes an insulative housing (1) which comprise a pair of side walls (121) and a pair of end walls (122) linking with two ends of the side wall, a plurality of terminals (2) retained in the side wall and a pair of grounding bridges (3) received in the end wall. Each of the grounding bridge comprise a contacting part (31) engaging with a mating connector, a grounding part (32) and a conducting part (33) mechanically connecting with the contacting part and grounding part. And the conductive part (33) has a larger resistance compared with the contacting part and the grounding part. Therefore, the power current transmitting through the guiding bridge (3) can be lower.
    Type: Application
    Filed: March 5, 2009
    Publication date: September 10, 2009
    Inventors: Yu-Hua Mao, Zhi-Hong Fang, Xue-Qing Zhang
  • Electrical connector having power terminals
    Publication number: 20090186497
    Abstract: An electrical connector (100) includes an insulative housing (1) comprising an engaging portion (12) which comprises a pair of side walls (121) and a pair of end walls (122), a plurality of signal terminals (2) arranged along the pair of the side walls (121) and at least one power terminals (3) located at each end wall (122). The end wall (122) defines at least one groove (120) extending along a mating direction at an outside thereof to receive and retain the at least one power terminal (3).
    Type: Application
    Filed: January 20, 2009
    Publication date: July 23, 2009
    Inventors: Yu-Hua Mao, Zhi-Hong Fang, Xue-Qing Zhang
  • NUCLEOSIDE ANALOGS WITH CARBOXAMIDINE MODIFIED MONOCYCLIC BASE
    Publication number: 20090176721
    Abstract: Novel nucleoside analog compounds are disclosed. The novel compounds or pharmaceutically acceptable esters or salts thereof may be used in pharmaceutical compositions, and such compositions may be used to treat an infection, an infestation, a neoplasm, or an autoimmune disease. The novel compounds may also be used to modulate aspects of the immune system, including modulation of Type 1 and Type 2 activity.
    Type: Application
    Filed: March 9, 2009
    Publication date: July 9, 2009
    Applicant: Valeant Pharmaceuticals North America
    Inventors: Robert Tam, Kanda Ramasamy, Zhi Hong, Johnson Lau
  • Electrical connector assembly having contacts without soldering legs
    Publication number: 20090163050
    Abstract: An electrical connector (100) assembled to a printed circuit board (5) for connecting with a mating connector, includes a longitudinal insulative housing (1) and a plurality of contacts (2, 3) received in the housing. Each of the contacts (2, 3) defines a retaining section (20, 30), a contacting portion (21) extending forwards from the retaining section for contacting with the mating connector and a compressing portion (220, 320) extending rearwards from the retaining section for connecting to the printed circuit board. The compressing portions are arranged in two rows, and the compressing portions nip and elastic compress against the printed circuit board instead of being soldered thereto to connect the electrical connector to the printed circuit board steadily.
    Type: Application
    Filed: December 22, 2008
    Publication date: June 25, 2009
    Inventors: Zhi-Hong Fang, Yu-Hua Mao
  • SYSTEM AND METHOD FOR DOWNLOADING TEXT CONTENT AND IMAGES IN WEB PAGES
    Publication number: 20090157633
    Abstract: A computer-based method for downloading text content and images in web pages is provided. The method includes downloading a web page as a temporary extensible markup language (XML) file in an application server, and searching the temporary XML file for predetermined information in the temporary XML file. The method further includes searching the temporary XML file for text content in the temporary XML file. Furthermore, the method includes converting a relative path of the image uniform resource locator (URL) to an absolute path by joining the URL of the web page to the front of the relative path of the image URL, and generating a local path for each image in the temporary XML file and storing each image into an application server according to the local path.
    Type: Application
    Filed: December 9, 2008
    Publication date: June 18, 2009
    Applicant: HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: CHUNG-I LEE, CHIEN-FA YEH, DA-PENG LI, ZHI-HONG LI
  • Saponins derived from and method of purifying the same
    Patent number: 7544668
    Abstract: Two hitherto unreported novel triterpene saponins were isolated in substantially pure form from the root of Ilex pubescens. The chemical structures and some properties of the triterpene saponin fraction have been elucidated to possess anti-inflammatory and analgesic activity. These two novel triterpene saponins and the triterpene saponin fraction may be used as pharmaceutical compositions in humans and mammals in need of such treatment.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: June 9, 2009
    Assignee: Hong Kong Baptist University
    Inventors: Liang Liu, Jing Rong Wang, Hua Zhou, Zhi Hong Jiang
  • Electrical connector with improved positioning device
    Patent number: 7537465
    Abstract: An electrical connector (100) includes an insulating housing (1) defining a front end portion and a rear end portion. At least one row of terminals (2) are retained in the housing (1) with tail portions (22) extending out of the rear end portion of the housing. A positioning device includes a first member integrally defined from the rear end portion of the housing and a second member (3) separately from the housing (1). The tail portions (22) of the terminals (2) are firstly pre-positioned by the first member and then positioned by the second member (3) of the positioning device when the second member is assembled on the housing.
    Type: Grant
    Filed: January 23, 2008
    Date of Patent: May 26, 2009
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Zhi-Hong Fang, Yu-Hua Mao
  • Cytotoxic compounds and conjugates
    Patent number: 7517903
    Abstract: The present disclosure provides drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-cleavable substrate conjugates, and to methods of treatment using them.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: April 14, 2009
    Assignee: Medarex, Inc.
    Inventors: Liang Chen, Sanjeev Gangwar, Vincent Guerlavais, Zhi-Hong Li, Bilal Sufi
  • DERIVATIVES OF N-(ARYLAMINO) SULFONAMIDES AS INHIBITORS OF MEK
    Publication number: 20090082457
    Abstract: This invention concerns N-(2-arylamino)aryl sulfonamides, which are inhibitors of MEK and are useful in treatment of cancer and other hyperproliferative diseases.
    Type: Application
    Filed: November 25, 2008
    Publication date: March 26, 2009
    Applicant: Andrea Biosciences, Inc.
    Inventors: Andreas MADERNA, Jean-Michel VERNIER, Dinesh BARAWKAR, Varaprasad CHAMAKURA, Hassan EL ABDELLAOUI, Zhi HONG
  • Maneuverable Domestic Cleaning Appliance
    Publication number: 20090077764
    Abstract: An upright floor vacuum cleaner comprising (a) a base having a vacuum nozzle disposed for cleaning the floor; (b) an upright handle having one end thereof connected to the base for pivotal movement thereon about a generally horizontal axis; (c) a suction source operative, upon energization, to create a vacuum in said nozzle; and, (d) a plurality of freely rotatable wheels mounted on said base each fully castered about a vertical axis and operative to permit free omni directional movement in translation and rotation of the base on the floor.
    Type: Application
    Filed: September 20, 2007
    Publication date: March 26, 2009
    Inventors: David Charles Hazen, Suzanne Ponikvar, Matthew Joseph Doerfler, Jack W. Gee, II, David Matthew Collins, David Khahil, Yung Leong Hin, Andrew A. Amberik, Henry Zhi Hong Chen
  • Laser level
    Patent number: 7508587
    Abstract: An optical system for a laser level is described. The laser level includes at least two optical systems which are parallel to and oppositely adjoin to each other in a same plane. Each optical system includes a laser light source, a regular lens, a diffusion lens, a beam-splitting element, and an outer casing as well as the regular lens and the diffusion lens are located between the laser light source and the beam-splitting element. For the optical system of the laser level, the laser beam is sequentially regularized, diffused and split into a fan-shaped light beam with an angle greater than 180 degrees to ensure that the light beams from the optical systems are spread in the same plane. Thus, the laser level generates a disk-shaped light beam with 360 degrees to indicate a circular mark in the same plane.
    Type: Grant
    Filed: January 5, 2005
    Date of Patent: March 24, 2009
    Assignee: Asia Optical Co., Inc.
    Inventors: Fang Zhi Hong, Chen Ye, Chen Yue Ye, Liu Hua Tang
  • Peptidyl prodrugs and linkers and stabilizers useful therefor
    Patent number: 7507420
    Abstract: The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as other diagnostic and therapeutic moieties. The invention provides prodrugs and conjugates of the duocarmycin analogues with the linker arms of the invention.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: March 24, 2009
    Assignee: Medarex, Inc.
    Inventors: Howard P. Ng, Danny P. C. McGee, Guoxian Wu, Jimmie Moore, Zhi-Hong Li, Sanjeev Gangwar, Oliver L. Saunders, Irina Astafieva
  • Electrical connector
    Patent number: D591687
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: May 5, 2009
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Yu-Hua Mao, Hong-Liang Wang, Zhi-Hong Fang
  • Electrical connector
    Patent number: D595232
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: June 30, 2009
    Assignee: Hon Hai Precision Ind. Co., Ltd
    Inventors: Yu-Hua Mao, Zhi-Hong Fang
  • Electrical connector
    Patent number: D599295
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: September 1, 2009
    Assignee: Hon Hai Precision Ind. Co., Ltd.
    Inventors: Yu-Hua Mao, Zhi-Hong Fang