Patents by Inventor Zhigang Guo
Zhigang Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12127376Abstract: A heat sink includes a heat sink fin (HSF), a first heat sink plate (HSP), and a second HSP that is opposite to the first HSP. The HSF is located on the first HSP. The second HSP is flexible. Further, an elastic component is disposed between the first HSP and the second HSP. The second HSP is in contact with a heat source component (HSC). Thus, when the heat sink is placed on the HSC, the second HSP contacts the HSC, the second HSP is deformed because the heat sink and the HSC are pressed against each other, and the elastic component between the first HSP and the second HSP is compressed such that heat generated by the HSC is transferred to the heat sink.Type: GrantFiled: August 9, 2022Date of Patent: October 22, 2024Assignee: HUAWEI TECHNOLOGIES CO., LTD.Inventor: Zhigang Guo
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Publication number: 20240129600Abstract: This application provides a video splitting method and an electronic device. When the method is performed by a server, the server processes a long video into a plurality of short videos, and then a terminal obtains the short video from the server and plays the short video; or when the method is performed by a terminal, the terminal obtains a long video from a server, and then the long video is processed into a plurality of short videos, and the plurality of short videos are played.Type: ApplicationFiled: December 21, 2023Publication date: April 18, 2024Applicant: Petal Cloud Technology Co., Ltd.Inventors: Wenbo WEI, Zhigang GUO, Youjun WANG
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Publication number: 20240095366Abstract: This application provides a secure boot apparatus and method. A control circuit in the secure boot apparatus can obtain boot code in a nonvolatile memory by using a non-programmable circuit, and verify the boot code by using a root of trust. In this way, even if the root of trust is not built in a processor, the verification on the boot code can be implemented by using the control circuit. This effectively reduces dependency of a secure boot process on processor performance. In addition, because the non-programmable circuit can be respectively coupled to the control circuit and the nonvolatile memory through two interfaces of different types, a requirement for the secure boot process on an interface protocol type of the control circuit is reduced, and application flexibility of a secure boot solution is improved.Type: ApplicationFiled: November 13, 2023Publication date: March 21, 2024Applicant: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Jilong Ye, Lizhong Qiao, Weicheng Gou, Tian Tang, Zhigang Guo
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Patent number: 11902636Abstract: This application provides a video splitting method and an electronic device. When the method is performed by a server, the server processes a long video into a plurality of short videos, and then a terminal obtains the short video from the server and plays the short video; or when the method is performed by a terminal, the terminal obtains a long video from a server, then processes the long video into a plurality of short videos, and plays the plurality of short videos.Type: GrantFiled: November 28, 2019Date of Patent: February 13, 2024Assignee: Petal Cloud Technology Co., Ltd.Inventors: Wenbo Wei, Zhigang Guo, Youjun Wang
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Publication number: 20230273050Abstract: A method for measuring a distance between connectors of different line cards is described. A first measurement component configured on a first line card sends a measurement signal to a second connector configured on a second line card using a first connector configured on a first line card, and determines a distance between the first connector and the second connector based on the measurement signal. The second connector receives the measurement signal and sends a response result of the measurement signal back to the first measurement component, to enable the first measurement component to determine the distance between the second connector and the first connector. The distance between the first connector and the second connector being determined based on the measurement signal enhances flexibility, universality, and accuracy.Type: ApplicationFiled: February 23, 2023Publication date: August 31, 2023Inventors: Zhigang GUO, Mingsong SHAO, Yufeng ZHENG, Houming ZHAI, Qiulai GUO
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Publication number: 20230172657Abstract: An electrode assembly for endoscopic surgery, including an electrode core wire (1), a telescopic control member (2) and an insulating outer sleeve (3). The electrode core wire (1) includes an electrode tip (101), a coaxial cable (102) and an electrode insulating tube (103). The electrode tip (101) is electrically coupled to an output end of an external host through the coaxial cable (102). The electrode insulating tube (103) sleeves on the electrode tip (101). The insulating outer sleeve (3) movably sleeves on the outside of the electrode core wire (1), and one end of the insulating outer sleeve (3) where the electrode tip (101) is located is a preset distance longer than the electrode insulating tube (103). The telescopic control member (2) is configured to control the movement of the insulating outer sleeve (3) so that the electrode tip 101 extends out of the insulating outer sleeve (3) or retracts into the insulating outer sleeve (3).Type: ApplicationFiled: June 12, 2020Publication date: June 8, 2023Inventors: Isamu NAKAHIRA, Zhigang GUO, Jianjiang QIAO, Yuchuan LU
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Publication number: 20230095984Abstract: A portable access box and a communications system are disclosed. The portable access box includes a housing, a power supply component, an interface component, and a transceiver component. The power supply component, the interface component, and the transceiver component are all located in the housing. The power supply component is separately electrically connected to the interface component and the transceiver component. The interface component is electrically connected to the transceiver component. The interface component is configured to establish a communication connection to a to-be-commissioned communications device. The transceiver component is configured to establish a communication connection to a remote device.Type: ApplicationFiled: September 23, 2022Publication date: March 30, 2023Inventors: Kai XU, Houming ZHAI, Zhigang GUO, Zhanwei ZHAO
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Publication number: 20230009150Abstract: This application relates to a circuit board assembly. The circuit board assembly includes: a first circuit board. The first circuit board is connected to a connector; and a second circuit board. A first connecting portion is disposed on the second circuit board. The first connecting portion is electrically connected to the connector. The second circuit board includes a top surface and a side surface. The top surface intersects and is perpendicular to the side surface. The first connecting portion is disposed on the top surface, and extends towards the side surface. In this disclosure, the top surface intersects and is perpendicular to the side surface, to improve stability of connection between the connector and the first connecting portion, and improve working stability of the second circuit board, so as to improve working performance of the circuit board assembly and improve user experience.Type: ApplicationFiled: July 6, 2022Publication date: January 12, 2023Inventors: Gang CHEN, Yufeng ZHENG, Zhe LI, Zhigang GUO, Xiaoliu ZHANG
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Publication number: 20220394875Abstract: A heat sink includes a heat sink fin (HSF), a first heat sink plate (HSP), and a second HSP that is opposite to the first HSP. The HSF is located on the first HSP. The second HSP is flexible. Further, an elastic component is disposed between the first HSP and the second HSP. The second HSP is in contact with a heat source component (HSC). Thus, when the heat sink is placed on the HSC, the second HSP contacts the HSC, the second HSP is deformed because the heat sink and the HSC are pressed against each other, and the elastic component between the first HSP and the second HSP is compressed such that heat generated by the HSC is transferred to the heat sink.Type: ApplicationFiled: August 9, 2022Publication date: December 8, 2022Inventor: Zhigang Guo
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Publication number: 20220347217Abstract: Provided are a CAR-T cell specifically recognizing CD70, and a preparation method therefor. The method comprises expressing a SCFV(Anti CD70)-CD8-4-1BB-CD3? molecule in a T cell. The CAR-T cell has tumor killing activity and may be used for preparing a medication in the treatment of a tumor with the high expression level of CD70 molecules.Type: ApplicationFiled: May 26, 2020Publication date: November 3, 2022Inventors: Zhigang GUO, Feng JI, Rui LIU, Ting WU, Enjie LI, Lulu LI, Menghan LI, Zhigang HU
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Patent number: 11286309Abstract: The invention discloses a brand-new PCSK9 antibody. The PCSK9 antibody is sieved through a phage display technology, then a full-length gene sequence is obtained through a gene engineering technology, and applied to preparation of the antibody, and the prepared antibody is high in yield and short in period and is a humanized antibody. The invention further discloses an anti-tumor effect of the antihuman PCSK9 antibody, which expands the way of thinking for research on occurrence and development of tumors in the future, and lays foundations for preparing the antihuman PCSK9 antibody into monoclonal antibody medicines used for treating tumors in the later period.Type: GrantFiled: January 2, 2020Date of Patent: March 29, 2022Assignee: ZHEJIANG BLUE SHIELD PHARMACEUTICAL CO., LTD.Inventors: Zhigang Guo, Li Jing, Ali Wajid
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Publication number: 20220021950Abstract: This application provides a video splitting method and an electronic device. When the method is performed by a server, the server processes a long video into a plurality of short videos, and then a terminal obtains the short video from the server and plays the short video; or when the method is performed by a terminal, the terminal obtains a long video from a server, then processes the long video into a plurality of short videos, and plays the plurality of short videos.Type: ApplicationFiled: November 28, 2019Publication date: January 20, 2022Inventors: Wenbo WEI, Zhigang GUO, Youjun WANG
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Publication number: 20210317217Abstract: The present invention belongs to the field of antibody drugs, and relates to a humanized anti-VEGFR2 single-chain antibody and use thereof. The single-chain antibody comprises a heavy chain variable region set forth in SEQ ID No. 1 and a light chain variable region set forth in SEQ ID No. 2, wherein the heavy chain variable region and the light chain variable region are connected via a flexible peptide with an amino acid sequence set forth in SEQ ID No. 3. The present invention also discloses use of the antibody in preparing a product for inhibiting tumor growth. The antibody disclosed herein can be used as a medicament for clinical use in indications caused by neovascularization.Type: ApplicationFiled: April 29, 2019Publication date: October 14, 2021Inventors: Zhigang GUO, Binghui SHEN, Laosheng WU
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Patent number: 10945391Abstract: Methods for introgressing an allele of interest of a locus associated with a yield trait into Zea mays germplasm are provided. In some embodiments, the methods include providing a Zea mays plant that contains an allele of interest of a locus associated with a yield trait, wherein the locus associated with the yield trait is identifiable by PCR amplification of a Zea mays nucleic acid with a pair of oligonucleotides primers as disclosed herein, and introgressing the allele of interest into Zea mays germplasm that lacks the allele. Also provided are methods for identifying Zea mays plants that contain at least one allele associated with improved yield, improved maize plants, elite Zea mays plants, biomass produced from improved Zea mays plants, isolated and purified genetic markers, and compositions that include an amplification primer pair capable of amplifying a Zea mays nucleic acid to generate a Zea mays marker amplicon.Type: GrantFiled: October 24, 2019Date of Patent: March 16, 2021Assignee: Syngenta Participations AGInventors: Venkata Krishna Kishore, Libardo Andres Gutierrez-Rojas, Zhigang Guo, Joseph Richard Byrum
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Publication number: 20200223943Abstract: The invention discloses a brand-new PCSK9 antibody. The PCSK9 antibody is sieved through a phage display technology, then a full-length gene sequence is obtained through a gene engineering technology, and applied to preparation of the antibody, and the prepared antibody is high in yield and short in period and is a humanized antibody. The invention further discloses an anti-tumor effect of the antihuman PCSK9 antibody, which expands the way of thinking for research on occurrence and development of tumors in the future, and lays foundations for preparing the antihuman PCSK9 antibody into monoclonal antibody medicines used for treating tumors in the later period.Type: ApplicationFiled: January 2, 2020Publication date: July 16, 2020Inventors: Zhigang Guo, Li Jing, Ali Wajid
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Publication number: 20200037527Abstract: Methods for introgressing an allele of interest of a locus associated with a yield trait into Zea mays germplasm are provided. In some embodiments, the methods include providing a Zea mays plant that contains an allele of interest of a locus associated with a yield trait, wherein the locus associated with the yield trait is identifiable by PCR amplification of a Zea mays nucleic acid with a pair of oligonucleotides primers as disclosed herein, and introgressing the allele of interest into Zea mays germplasm that lacks the allele. Also provided are methods for identifying Zea mays plants that contain at least one allele associated with improved yield, improved maize plants, elite Zea mays plants, biomass produced from improved Zea mays plants, isolated and purified genetic markers, and compositions that include an amplification primer pair capable of amplifying a Zea mays nucleic acid to generate a Zea mays marker amplicon.Type: ApplicationFiled: October 24, 2019Publication date: February 6, 2020Applicant: SYNGENTA PARTICIPATIONS AGInventors: Venkata Krishna Kishore, Libardo Andres Gutierrez-Rojas, Zhigang Guo, Joseph Richard Byrum
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Patent number: 10492393Abstract: Methods for introgressing an allele of interest of a locus associated with a yield trait into Zea mays germplasm are provided. In some embodiments, the methods include providing a Zea mays plant that contains an allele of interest of a locus associated with a yield trait, wherein the locus associated with the yield trait is identifiable by PCR amplification of a Zea mays nucleic acid with a pair of oligonucleotides primers as disclosed herein, and introgressing the allele of interest into Zea mays germplasm that lacks the allele. Also provided are methods for identifying Zea mays plants that contain at least one allele associated with improved yield, improved maize plants, elite Zea mays plants, biomass produced from improved Zea mays plants, isolated and purified genetic markers, and compositions that include an amplification primer pair capable of amplifying a Zea mays nucleic acid to generate a Zea mays marker amplicon.Type: GrantFiled: June 22, 2018Date of Patent: December 3, 2019Assignee: Syngenta Participations AGInventors: Venkata Krishna Kishore, Libardo Andres Gutierrez-Rojas, Zhigang Guo, Joseph Byrum
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Patent number: 10160762Abstract: The present invention is directed to 6-alkyl dihydropyrazolopyrimidinone compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis, Parkinson's disease, Parkinson's disease dementia (PDD), or Huntington's disease, and those associated with striatal hypo-function or basal ganglia dysfunction.Type: GrantFiled: May 24, 2016Date of Patent: December 25, 2018Assignee: Merck Sharp & Dohme Corp.Inventors: Dong-Ming Shen, Michael P. Dwyer, Christopher J. Sinz, Deping Wang, Shawn J. Stachel, Daniel V. Paone, Ashley Forster, Richard Berger, Yili Chen, Yimin Qian, Shimin Xu, Chunmei Hu, William D. Shipe, Jianmin Fu, Zhigang Guo, Haitang Li, Yingjian Bo
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Patent number: 10129183Abstract: A method for managing a connection apparatus and a connection apparatus are disclosed. In an embodiment the connection apparatus includes a first connector configured to be connected to a service processing unit, a second connector configured to be connected to a first switching unit, a third connector configured to be connected to a second switching unit, wherein the third connector is further configured to be disconnected from the second switching unit and connected to the first switching unit. The apparatus further comprises a first transmission medium, a second transmission medium, one end of the first transmission medium being directly connected to the first connector, one end of the second transmission medium being directly connected to the first connector, another end of the first transmission medium being directly connected to the second connector, and another end of the second transmission medium being directly connected to the third connector.Type: GrantFiled: May 22, 2015Date of Patent: November 13, 2018Assignee: Huawei Technologies Co., LtdInventors: Chongyang Wang, Zhigang Guo
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Publication number: 20180288955Abstract: Methods for introgressing an allele of interest of a locus associated with a yield trait into Zea mays germplasm are provided. In some embodiments, the methods include providing a Zea mays plant that contains an allele of interest of a locus associated with a yield trait, wherein the locus associated with the yield trait is identifiable by PCR amplification of a Zea mays nucleic acid with a pair of oligonucleotides primers as disclosed herein, and introgressing the allele of interest into Zea mays germplasm that lacks the allele. Also provided are methods for identifying Zea mays plants that contain at least one allele associated with improved yield, improved maize plants, elite Zea mays plants, biomass produced from improved Zea mays plants, isolated and purified genetic markers, and compositions that include an amplification primer pair capable of amplifying a Zea mays nucleic acid to generate a Zea mays marker amplicon.Type: ApplicationFiled: June 22, 2018Publication date: October 11, 2018Applicant: Syngenta Participations AGInventors: Venkata Krishna Kishore, Andres Gutierrez-Rojas, Zhigang Guo, Joseph