Patents by Inventor Zhigang Hao

Zhigang Hao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9993414
    Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: June 12, 2018
    Assignee: Colgate-Palmolive Company
    Inventors: Zhigang Hao, Ying Yang, Zhiqiang Liu, Katherine Hu, Guofeng Xu, Paul Joseph Vincenti
  • Patent number: 9901523
    Abstract: Described herein are oral care compositions comprising a mixture of zinc oxide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: February 27, 2018
    Assignee: Colgate-Palmolive Company
    Inventors: Guofeng Xu, Zhiqiang Liu, Long Pan, LaTonya Kilpatrick-Liverman, Ying Yang, Michael A. Stranick, Zhigang Hao
  • Patent number: 9861563
    Abstract: The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: January 9, 2018
    Assignee: Colgate-Palmolive Company
    Inventors: LaTonya Kilpatrick-Liverman, Zhiqiang Liu, Long Pan, Ying Yang, Guofeng Xu, Michael A. Stranick, Zhigang Hao
  • Patent number: 9823236
    Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: November 21, 2017
    Assignee: Colgate-Palmolive Company
    Inventors: Zhigang Hao, Deborah A. Peru, Joe Vazquez, Jessica Monk, Harsh M. Trivedi, Paul Joseph Vincenti, Osman Khalid, Ariel Haskel
  • Patent number: 9757320
    Abstract: Provided herein is an oral care composition comprising an orally-acceptable aqueous vehicle and an antimicrobial ingredient, wherein the antimicrobial ingredient comprises a zinc ascorbylphosphate and methods for treating or preventing a disease or disorder of the oral cavity using the oral care compositions disclosed herein.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: September 12, 2017
    Assignee: Colgate-Palmolive Company
    Inventors: Zhigang Hao, Ying Yang, Zhiqiang Liu, Xu Guofeng, Paul Joseph Vincenti
  • Publication number: 20170231879
    Abstract: Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na5P3O10), and oral care compositions comprising the complex and uses thereof.
    Type: Application
    Filed: December 29, 2016
    Publication date: August 17, 2017
    Inventors: Shiri NAWROCKI, Viktor DUBOVOY, Long PAN, Zhigang HAO, Nihal DOGU
  • Publication number: 20170035677
    Abstract: Aqueous and substantially non-aqueous oral compositions comprising a cationic steroidal compound are suitable for treating conditions of the oral cavity.
    Type: Application
    Filed: October 25, 2016
    Publication date: February 9, 2017
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventors: Joe Vazquez, Dandan Chen, Harsh M. Trivedi, Ammanuel Mehreteab, Laurence Du-thumm, Gregory Szewczyk, Zhigang Hao, Carl A. Genberg
  • Publication number: 20160271615
    Abstract: A roller mill includes a shell provided with a feed port and a discharge port; a main shaft inserted in the shell and rotatable in the shell; a drive device drivingly connected to the main shaft a holder mounted on the main shaft two or more than two grinding rollers, each of the grinding rollers mounted on the holder and rotatable around its own axis; and a grinding disk fixedly mounted in the shell at a position opposite to the multiple grinding rollers. The roller mill further includes an axial position adjustment device connected to the main shaft and configured to drive the main shaft to move axially to adjust a position of the main shaft.
    Type: Application
    Filed: November 4, 2014
    Publication date: September 22, 2016
    Inventor: Zhigang HAO
  • Patent number: 9345655
    Abstract: Aqueous oral compositions containing a cationic steroidal compound and a quaternary ammonium compound are suitable for treating conditions of the oral cavity.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: May 24, 2016
    Assignee: BRIGHAM YOUNG UNIVERSITY
    Inventors: Joe Vazquez, Dandan Chen, Harsh M. Trivedi, Ammanuel Mehreteab, Laurence Du-Thumm, Gregory Szewzyk, Zhigang Hao
  • Publication number: 20160121334
    Abstract: A hammer crusher includes a shell provided with a feed port, a main shaft rotatably arranged on the shell, a hammer bracket arranged on the main shaft, and a hammer shaft arranged on the hammer bracket, wherein at least one hammerhead is arranged on the hammer shaft, and the at least one hammerhead includes at least one material moving hammerhead configured to axially move materials. The material inside the crushing cavity can be compulsively moved axially by the at least one material moving hammerhead. Thus, the crushing time of the materials can be prolonged, and on the other hand the granule with small size can easily pass through, which leads to a larger yield and a lower power consumption.
    Type: Application
    Filed: May 27, 2014
    Publication date: May 5, 2016
    Inventor: Zhigang Hao
  • Publication number: 20160045421
    Abstract: Described herein are aqueous oral compositions comprising cationic steroidal compound and a quaternary ammonium compound; and methods for making and using the same.
    Type: Application
    Filed: October 29, 2015
    Publication date: February 18, 2016
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventors: Joe Vazquez, Dandan Chen, Harsh M. Trivedi, Ammanuel Mehreteab, Laurence Du-Thumm, Gregory Szewczyk, Zhigang Hao
  • Publication number: 20160008254
    Abstract: Provided herein is an oral care composition comprising an orally-acceptable aqueous vehicle and an antimicrobial ingredient, wherein the antimicrobial ingredient comprises a zinc ascorbylphosphate and methods for treating or preventing a disease or disorder of the oral cavity using the oral care compositions disclosed herein.
    Type: Application
    Filed: December 19, 2012
    Publication date: January 14, 2016
    Inventors: Zhigang Hao, Ying Yang, Zhiqiang Liu, Xu Guofeng, Paul Joseph Vincenti
  • Publication number: 20150328112
    Abstract: Described herein are oral care compositions comprising a mixture of zinc oxide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
    Type: Application
    Filed: December 19, 2012
    Publication date: November 19, 2015
    Applicant: Colgate-Palmolive Company
    Inventors: Guofeng Xu, Zhiqiang Liu, Long Pan, LaTonya Kilpatrick-Liverman, Ying Yang, Michael A. Stranick, Zhigang Hao
  • Publication number: 20150328096
    Abstract: The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
    Type: Application
    Filed: December 19, 2012
    Publication date: November 19, 2015
    Applicant: Colgate-Palmolive Company
    Inventors: LaTonya Kirkpatrick-Liverman, Zhiqiang Liu, Long Pan, Ying Yang, Guofeng Xu, Michael A. Stranick, Zhigang Hao
  • Publication number: 20150328120
    Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.
    Type: Application
    Filed: December 17, 2012
    Publication date: November 19, 2015
    Applicant: Colgate-Palmolive Company
    Inventors: Zhigang Hao, Ying Yang, Zhiqiang Liu, Katherine Hu, Guofeng Xu, Paul Joseph Vincenti
  • Publication number: 20150293075
    Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
    Type: Application
    Filed: December 21, 2012
    Publication date: October 15, 2015
    Applicant: Colgate-Palmolive Company
    Inventors: Zhigang Hao, Deborah A. Peru, Joe Vazquez, Jessica Monk, Harsh M. Trivedi, Paul Joseph Vincenti, Osman Khalid, Ariel Haskel
  • Publication number: 20150265183
    Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
    Type: Application
    Filed: December 21, 2012
    Publication date: September 24, 2015
    Inventors: Zhigang Hao, Deborah A. Peru, Joe Vazquez, Jessica Monk, Harsh M. Trivedi, Paul Joseph Vincenti, Osman Khalid
  • Publication number: 20140369941
    Abstract: Described herein are aqueous oral compositions comprising cationic steroidal compound and a quaternary ammonium compound; and methods for making and using the same.
    Type: Application
    Filed: December 21, 2011
    Publication date: December 18, 2014
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventors: Joe Vazquez, Dandan Chen, Harsh M. Trivedi, Ammanuel Mehreteab, Laurence Du-Thumm, Gregory Szewczyk, Zhigang Hao
  • Publication number: 20140363780
    Abstract: Described herein are aqueous and substantially non-aqueous oral compositions comprising a cationic steroidal compound and methods of making and using the same.
    Type: Application
    Filed: July 23, 2014
    Publication date: December 11, 2014
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventors: Joe Vazquez, Dandan Chen, Harsh M. Trivedi, Ammanuel Mehreteab, Laurence Du-Thumm, Gregory Szewczyk, Zhigang Hao
  • Patent number: 8157196
    Abstract: A grinding device of vertical grinder, comprising a driving device (1); a vertical grinding barrel (2) which is driven by the driving device; a grinding roller (3); and a pressure applying device (4) acting on the grinding roller (3); a running-in surface is composed of the roller surface of the grinding roller and the grinding surface (6) of the inner lining of the vertical grinding barrel, and the angular separation between the grinding surface (6) of the inner lining of the vertical grinding barrel and the vertical line is 40 degrees to ?5 degrees. The device is also provided with a material-shaving device (9).
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: April 17, 2012
    Inventor: Zhigang Hao