Abstract: This invention relates to a composition and a method for prediction of a response to Trastuzumab therapy in a breast cancer patient, and more specifically, a composition, a kit, a DNA chip, and a method for predicting a response to Trastuzumab therapy by using polynucleotides each comprising a nucleotide sequence represented by any of SEQ ID NOs: 1 to 9, 11 to 19, and 21 to 23 in the Sequence Listing or a nucleotide sequence derived therefrom by substitution of u with t, mutants thereof, derivatives thereof, or fragments thereof comprising at least 16 continuous nucleotides, or a polynucleotide comprising a complementary sequence thereof, and using an increase or decrease in Her2 protein expression level as an indicator.

Abstract: A production method of a magnetic recording medium of the present invention includes: a step of forming a magnetic layer (2) on a non-magnetic substrate (1); a step of forming a dissoluble layer (3) on the magnetic layer (2); a step of forming a mask layer (4) on the dissoluble layer (3); a step of patterning the dissoluble layer (3) and the mask layer (4) to a shape corresponding to a magnetic recording pattern (2a); a step of performing a partial modification or removal of the magnetic layer (2) by use of the patterned mask layer (4); and a step of dissolving the dissoluble layer (3) with a chemical agent so as to remove the dissoluble layer (3) together with the mask layer (4) formed thereon from the top of the magnetic layer (2), wherein the magnetic recording medium has the magnetically-separated magnetic recording pattern (2a).

Abstract: A method for producing a magnetic recording medium which includes: forming a magnetic layer on a non-magnetic substrate; forming a dissolution layer on the magnetic layer; forming a mask layer on the dissolution layer; patterning the dissolution layer and the mask layer so as to have a pattern corresponding to a magnetic recording pattern; partially modifying or removing a part of the magnetic layer and the mask layer not covered with the dissolution layer; and dissolving the dissolution layer and removing the dissolution layer together with the mask layer which is on the dissolution layer from the surface of the magnetic layer. The dissolution layer is formed by coating a solution containing an organic silicon compound dissolved in an organic solvent on the magnetic layer, and solidifying the coated chemical solution in the step in which the dissolution layer is formed on the magnetic layer.

Abstract: Disclosed are a flow-through washing method and a flow-through washing apparatus which efficiently remove dust adhering to the surface of a substrate and prevent dust from adhering to the surface of the substrate again after washing. The flow-through washing method runs washing liquid (L) inside a washing tank (2) in the lateral direction, and applies an ultrasonic vibration to the washing liquid (L) in a state in which an object (W) to be washed is immersed in this washing liquid (L), whilst washing this object (W). By regulating the flow rate of the washing liquid (L) flowing in any of the feed ports (3) and/or discharge ports (5) of a plurality of feed ports (3) which feed the washing liquid (L) to the washing tank (2) and plurality of discharge ports (5) which discharge washing liquid (L) from the washing tank (2), the washing liquid (L) inside the washing tank (2) can be set so as to run in a laminar flow state.