Abstract: Antibody antigen binding domains which specifically binds human leptin comprises VH or VL CDR1, CDR2 and CDR3 sequences of an hLept antibody. The antibody antigen binding domains and antibodies thereof are useful to treat obesity and diabetes.

Abstract: A display substrate is provided, the display substrate has a plurality of sub-pixels arranged in an array, and includes a driving circuit substrate, a plurality of first electrodes, a pixel definition layer and a light-emitting material layer. The pixel definition layer is at least on a side of the plurality of first electrodes away from the driving circuit substrate, and includes a plurality of sub-pixel openings respectively exposing the plurality of first electrodes and at least one partition structure on the pixel definition layer. The light-emitting material layer is on a side of the pixel definition layer away from the driving circuit substrate and at least in the plurality of sub-pixel openings, the pixel definition layer includes a first pixel definition sub-layer and a second pixel definition sub-layer, and a width of the second pixel definition sub-layer is greater than a width of the first pixel defining sub-layer.

Abstract: A calibration assembly, including: a base; and a plurality of calibration wires dispersedly connected to the base. An absorption capacity of the calibration wire for X rays is greater than that of the base for X rays. Through a specific structure design of a plurality of calibration wires in the calibration assembly, the calibration wires are dispersedly connected to the base, and taking advantage of the characteristics that the absorption capacity of the calibration wire for X rays is greater than that of the base for X rays, the calibration wires are applied to the calibration phantom, and the calibration phantom is scanned in the scanning system. By continuously adjusting the geometric parameter values in the imaging method, the optimal geometric parameter values that are closest to the real scanning system structure may be obtained, thereby improving the imaging effect of the scanning system.

Abstract: An inspection system and method, the inspection system includes: a carrying device, at least one ray source and a detector assembly. The ray source and the detector assembly are lifted or lowered along a central axis of the carrying device relative to the carrying device. When viewed along the central axis, the ray source is translatable between scanning positions relative to the carrying device. When the ray source is at one of the scanning positions the ray source and the detector assembly are lifted or lowered relative to the carrying device along the central axis, and the ray source emits X-rays; and when the ray source and the detector assembly are lifted or lowered a predetermined distance the ray source translates to another scanning position. The inspection system further reconstructs a three-dimensional scanning image of the object to be inspected based on detection data of the detector assembly.

Abstract: A method for micro-ridge mixed-sowing cultivation of rice includes: S1: draining away water at the maturity stage of the preceding crop until reaching a state allowing a harvester to operate; S2: harvesting the preceding crop, leaving the stubble, smashing the stalks of the preceding crop, and then spreading the smashed stalks on the stubble to form a rhizosphere layer for rice growth; S3: trenching the field to form ecological trenches; S4: flattening the standing stubble and the smashed stalks on the seedbed surface to form an underlying surface, molding seed-fertilizer-soil compounds into a ridge shape and fall the seed-fertilizer-soil compounds on the underlying surface to form ecological ridges, wherein a plurality of ecological ridges are formed between adjacent ecological trenches, and the seed-fertilizer-soil compounds are obtained by thoroughly mixing rice seeds, chemical fertilizers and soil at a mass ratio of 6 to 14:50 to 70:6,000 to 10,000.

Abstract: A display module, including: a first substrate (1); a second substrate (2); a liquid crystal layer (3); the display module further includes a first polarizing film (4), a first one-half wave plate (51) and a first quarter wave plate (52); the first quarter wave plate (52), the first one-half wave plate (51) and the first polarizing film (4) are on a side of the first substrate (1) away from the liquid crystal layer (3) and are sequentially stacked in a direction away from the first substrate (1); an angle between an absorption axis of the first polarizing film (4) and a first direction is in a range of 85° to 105°; an angle between a slow axis of the first one-half wave plate (51) and the first direction is in a range of 105° to 125°.

Abstract: The present disclosure relates to a display panel and a terminal device. The display panel includes a display region. At least a part of the display region is a transparent region. The transparent region has a plurality of pixel rows distributed along a column direction, and each of the plurality of pixel rows includes pixels and transparent portions arranged in a row direction. The pixel rows include first pixel rows and second pixel rows, transparent portions each arranged between two adjacent pixels in each of the first pixel rows are first transparent portions, and transparent portions each arranged between two adjacent pixels in each of the second pixel rows are second transparent portions. A width of each of the first transparent portions in the row direction is greater than a width of each of the second transparent portions in the row direction.

Abstract: A trailer carriage includes two longitudinal beams and at least two cross beams between the two longitudinal beams. The longitudinal beam includes a side wall, an upper connecting wall and a lower connecting wall. The cross beam includes an upper connecting plate, a lower connecting plate below the upper connecting plate, and an end plate between the upper connecting plate and the lower connecting plate. The upper connecting plate abuts against a bottom of the upper connecting wall, the lower connecting plate abuts against a top of the lower connecting wall, the end plate abuts against an inner side of the side wall. The upper connecting plate is connected with the upper connecting wall via a first huck bolt, the lower connecting plate is connected with the lower connecting wall via a second huck bolt, the end plate is connected with the side wall via a third huck bolt.

Abstract: A touch-control panel and a touch-control displaying device, which relates to the technical field of touch control. In the present application, by providing the first carrier element, the first electrically conductive layer and the first shadow eliminating layer on the substrate, by blocking the first electrically conductive layer by using the first shadow eliminating layer, the reflectivity of the first electrically conductive layer is reduced, which reduces the pattern of the first electrically conductive layer being observed under intensive-light reflection.

Abstract: A display substrate and a display device relate to the technical field of displaying. The display substrate includes a plurality of display units spaced apart from each other and a plurality of connection units, the plurality of connection units being connected between two adjacent display units; the plurality of connection units include: two connection units arranged along a first direction, wherein the first direction is parallel to a stretching direction of the display substrate; wherein the two connection units arranged along the first direction are axisymmetric with respect to a first reference line, so that the plurality of connection units arranged along a second direction have a same deformation amount in a stretching state, the second direction is perpendicular to the stretching direction, and an extension direction of the first reference line is parallel to the second direction.

Abstract: A locking mechanism of a trailer carriage includes a transmission shaft, two bolts, an airbag, and a swing arm. The transmission shaft is pivoted to the carriage and extends in a length direction of the carriage; the two bolts are movably connected to two sides of the carriage in a penetrating manner, the bolt is movable in a width direction of the carriage between a first position where the bolt is accommodated in the carriage and a second position where the bolt protrudes from a side edge of the carriage; and one end of the swing arm is connected to the transmission shaft and a connecting seat is formed at the other end of the swing arm, and one end of the airbag is connected to the carriage and the other end of the airbag is connected to the connecting seat.

Abstract: The present disclosure provides an isolated monoclonal antibody or an antigen-binding fragment thereof that binds specifically to leukocyte immunoglobulin-like receptor 4 (LILRB4). In certain embodiments, the antibody or antigen-binding fragment, when bound to LILRB4, modulates the activation of LILRB4. In certain embodiments, the antibody or antigen-binding fragment, when bound to LILRB4, activates LILRB4. In certain embodiments, the antibody or antigen binding fragment, when bound to LILRB4, suppresses activation of LILRB4. In certain embodiments, the antibody or antigen-binding fragment, when bound to LILRB4, specifically blocks binding of ApoE to LILRB4. In another aspect, there is provided a method of treating or ameliorating the effects of a cancer in a subject, comprising administering to the subject a therapeutically effective amount of the antibody or an antigen-binding fragment thereof or an engineered cell as provided herein.

Abstract: An oscillation period detection circuit and method, and semiconductor memory are provided. The oscillation period detection circuit includes an oscillator module, a control module, and a counting module. The oscillator module includes a target oscillator, and is configured to receive an enable signal and control the target oscillator to output an oscillation clock signal according to the enable signal; the control module is configured to receive the enable signal and the oscillation clock signal, and perform valid time reforming processing according to the oscillation clock signal and the enable signal to determine a target time; the counting module is configured to receive the enable signal and the oscillation clock signal, and perform period counting processing according to the enable signal and the oscillation clock signal to determine a target period number. The oscillation period of the target oscillator is calculated according to the target time and the target period number.

Abstract: A positioning system and method for a maglev train, the positioning system comprising an onboard magnet mounted at the bottom of a train, two grating arrays laid on train tracks side by side in the traveling direction of the train, an optical pulse generation module and a data processing module. The data processing module performs first-stage train positioning according to drift conditions of the center wavelengths of the marking gratings, performs second-stage train positioning according to drift conditions of the center wavelengths of the first grating array, and performs third-stage train positioning according to drift conditions of the central wavelengths of the second grating array, so as to determine the track positions where the train arrives step by step.

Abstract: A chip of a LED, comprising: a current blocking layer including a first current blocking layer grown along an epitaxial layer and a plurality of second current blocking layers disposed at one end of the first current blocking layer at intervals, the first current blocking layer gradually widens along a direction away from the second current blocking layers; a transparent conductive layer including a first transparent conductive layer and a second transparent conductive layer grown on the epitaxial layer, the first transparent conductive layer is grown on the current blocking layer and at least partially overlapped with the second current blocking layers; a metal finger electrode having a width gradually narrowed from the first end to the second end thereof and smaller than the width of the first current blocking layer, and the second current blocking layers are distributed around the first end of the metal finger electrode.

Abstract: This application provides a palm contour extraction method performed by a computer device. The method includes: obtaining bone point information respectively corresponding to palm bone points in a target palm image, the bone point information including bone point positions and bone point types; matching the palm bone points based on the bone point positions and the bone point types, to obtain a plurality of palm bone point sets, each palm bone point set having a corresponding geometry processing type for a corresponding set of palm bone points in the target palm image; determining a plurality of palm contour points from the plurality of palm bone point sets based on their respective geometry processing type; and generating a palm contour corresponding to the target palm image based on the plurality of palm contour points.

Abstract: An impedance calibration circuit, an impedance calibration method, and a memory are provided. The impedance calibration circuit includes a parameter module, an initial value generation module, and a calibration module. The parameter module is configured to perform environment detection processing and output an environment parameter signal; the initial value generation module is configured to receive the environment parameter signal, and output an initial calibration value based on the environment parameter signal when the calibration instruction signal is received; and the calibration module is configured to receive the initial calibration value, and perform impedance calibration processing based on the initial calibration value when the calibration instruction signal is received.

Abstract: A flexible support includes a first mounting channel for mounting a flexible water pipe, a second mounting channel for mounting a flexible supporting and positioning mechanism, a first connecting end, a second connecting end, and a support body. The support body capable of being bent and deformed. The support body coupled between the first connecting end and the second connecting end. The second mounting channel is located on one side of the first mounting channel. The first mounting channel and the second mounting channel respectively penetrate through the first connecting end, the support body and the second connecting end in sequence.

Abstract: Updates to a payment card of the specific card user that will affect subsequent payments to the COF merchants has occurred are detected based on receiving a notification from an issuer processor. In response, payment credentials can be automatically updated with the COF merchants for the specific card user.