Patents by Inventor Zhiyuan Zhang

Zhiyuan Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dipeptidyl peptidase inhibitors
    Patent number: 7781584
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C?NR9; and each L, X, R1, R2, and R3 are as defined herein.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: August 24, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Zhiyuan Zhang, Bruce J. Elder, Paul K. Isbester, Grant J. Palmer, Jonathon S. Salsbury, Luckner G. Ulysse
  • RENIN INHIBITORS
    Publication number: 20100137310
    Abstract: The invention provides compounds, pharmaceutical compositions, kits, method of preparing, and method of using the compounds which exhibit renin and other S9 proteases activities and consist of the formula:—wherein the variables are as defined herein.
    Type: Application
    Filed: March 11, 2008
    Publication date: June 3, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Stephen L. Gwaltney, Betty Lam, Zhiyuan Zhang
  • Dipeptidyl peptidase inhibitors
    Patent number: 7723344
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: May 25, 2010
    Assignee: Takeda San Diego, Inc.
    Inventors: Jun Feng, Stephen L. Gwaltney, II, Stephen W. Kaldor, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • Kinase inhibitors
    Patent number: 7713973
    Abstract: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: May 11, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Qing Dong, David J. Hosfield, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • RENIN INHIBITORS
    Publication number: 20100105665
    Abstract: Compounds, pharmaceutical compositions, kits, article of manufacture, methods of using, and method of preparing of compounds having the formula of: wherein the variables are as defined herein.
    Type: Application
    Filed: January 9, 2008
    Publication date: April 29, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Lily Kwok, Betty Lam, Zhe Li, Zhiyuan Zhang
  • Dipeptidyl peptidase inhibitors
    Patent number: 7687625
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 protease that comprise a compound comprising the formula: wherein Q is selected from the group of CO, SO, SO2, or C?NR9; and R1, R2, R3 and R4 are as defined herein.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: March 30, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jun Feng, Stephen L. Gwaltney, Stephen W. Kaldor, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • cMET INHIBITORS
    Publication number: 20100063054
    Abstract: Compounds of the following formula are provided for use with cMET: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: August 14, 2009
    Publication date: March 11, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Jerome C. Bressi, Shaosong Chu, Philip Erickson, Mallareddy Komandla, Lily Kwok, John D. Lawson, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang, Sanjib Das
  • Dipeptidyl peptidase inhibitors
    Patent number: 7638638
    Abstract: Pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound with the formula: where the labeled substituents are as described herein.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: December 29, 2009
    Assignee: Takeda San Diego, Inc.
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Michael B. Wallace, Xiao-Yi Xiao, Zhiyuan Zhang
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20090275750
    Abstract: Methods of making compounds of the formula (I) wherein the variables are as defined herein. Also, methods of making compounds that may be used to inhibit dipeptidyl peptidase.
    Type: Application
    Filed: September 15, 2006
    Publication date: November 5, 2009
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Zhiyuan Zhang, Paul R. Brodluahrer, Bruce Elder, Paul Isbester, Richard S. Fornicola, Philip B. Kisanga, Bingidimi I. Mobele, Grant J. Palmer, Maxwell M. Reeve, Jonathon S. Salsbury, Luckner Ulysse, Sripathy Venkatraman
  • METHOD, SYSTEM AND DEVICE FOR INCREASING MULTIMEDIA MESSAGING SERVICE SYSTEM CAPACITY
    Publication number: 20090233618
    Abstract: A method for increasing multimedia messaging service system capacity is provided, it comprises: a message distributing device determining a first multimedia messaging service center (MMSC) node for receiving multimedia message, and forwarding the multimedia message to a relay of the first MMSC node, after it having received multimedia message; the multimedia message being transmitted to a server of the first MMSC node by the relay of the first MMSC node, and stored in the server of the first MMSC node; the server of the first MMSC node corresponding to the relay of the first MMSC relay uniquely; the server of the first MMSC node sending the multimedia message to the receipt party via the relay of the first MMSC node and the message distributing device. A system and a device for increasing multimedia messaging service system capacity are provided, too. It can increase the capacity of multimedia messaging service system handling multimedia message service with the invention.
    Type: Application
    Filed: May 28, 2009
    Publication date: September 17, 2009
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Guangchang Bai, Dawei Li, Zhiyuan Zhang, Weiming Cheng, Yang Wang
  • Dipeptidyl peptidase inhibitors
    Patent number: 7550590
    Abstract: Compounds, pharmaceuticals, kits, and methods are provided for use with DPP-IV and other S9 protease that comprise a compound comprising the formula: wherein Q is selected from the group of CO, SO, SO2, or C?NR9; and R1, R2, R3 and R4 are as defined herein.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: June 23, 2009
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jun Feng, Stephen L. Gwaltney, Stephen W. Kaldor, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20090012059
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C?NR9; and each L, X, R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: October 30, 2007
    Publication date: January 8, 2009
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Zhiyuan Zhang, Bruce J. Elder, Paul K. Isbester, Grant J. Palmer, Jonathon S. Salsbury, Luckner G. Ulysse
  • Dipeptidyl peptidase inhibitors
    Patent number: 7470700
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: December 30, 2008
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jun Feng, Stephen L. Gwaltney, II, Stephen W. Kaldor, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20080188501
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C?NR9; and each L, X, R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 7, 2008
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Zhiyuan Zhang, Bruce J. Elder, Paul K. Isbester, Grant J. Palmer, Jonathon S. Salsbury, Luckner G. Ulysse
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20080177064
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C?NR9; and each L, X, R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 24, 2008
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Zhiyuan Zhang, Bruce J. Elder, Paul K. Isbester, Grant J. Palmer, Jonathon S. Salsbury, Luckner G. Ulysse
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20080161562
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C?NR9; and each L, X, R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 3, 2008
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Zhiyuan Zhang, Bruce J. Elder, Paul K. Isbester, Grant J. Palmer, Jonathon S. Salsbury, Luckner G. Ulysse
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20080108808
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C?NR9; and each L, X, R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 8, 2008
    Inventors: Jun Feng, Stephen Gwaltney, Jeffrey Stafford, Zhiyuan Zhang, Bruce Elder, Paul Isbester, Grant Palmer, Jonathon Salsbury, Luckner Ulysse
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20080108807
    Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising: wherein M is N or CR4; Q1 and Q2 are each independently selected from the group consisting of CO, SO, SO2, and C?NR9; and each L, X, R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 8, 2008
    Inventors: Jun Feng, Stephen Gwaltney, Jeffrey Stafford, Zhiyuan Zhang, Bruce Elder, Paul Isbester, Grant Palmer, Jonathon Salsbury, Luckner Ulysse
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20080003283
    Abstract: Compounds are provided for use with DPP-IV of the formula: Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: August 7, 2007
    Publication date: January 3, 2008
    Applicant: TAKEDA PHARMACEUTICAL COMPANY, INC.
    Inventors: Jun Feng, Stephen Gwaltney, Jeffrey Stafford, Zhiyuan Zhang, Bruce Elder, Paul Isbester, Grant Palmer, Jonathan Salsbury, Luckner Ulysse
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20070249611
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound of the formula: wherein the substituents are as defined herein.
    Type: Application
    Filed: March 27, 2007
    Publication date: October 25, 2007
    Inventors: Jun Feng, Stephen Gwaltney, Michael Wallace, Zhiyuan Zhang