Abstract: The invention provides methods of treating male reproductive senescence comprising administering to a male in need thereof a necroptosis inhibitor, including inhibitors of RIP1, RIP3 or MLKL. The invention also provides pharmaceutical compositions comprising a necroptosis inhibitor and a second different drug for treating male senescence.

Abstract: The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.

Abstract: The invention provides compounds that inhibit human MLKL, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition.

Abstract: Embodiments of the present disclosure provide devices, techniques, and configurations for network interface controllers (NICs) that log write packets received from a network in non-volatile random access memory (NVRAM). In one embodiment, a NIC includes a network interface to couple a host of the NIC to a network, a NVRAM, and a controller coupled with the network interface and the NVRAM, where the controller is to log write packets received at the network interface from the network in the NVRAM. Other embodiments may be described and/or claimed.

Abstract: Provided is an apparatus directing to a speculative read mechanism for a distributed storage system. The apparatus includes a remote direct memory access (RDMA) network interface card (RNIC) (100) for a server (250), wherein the RNIC (100) includes an onboard memory (105), a trigger control (120) and a port for connection of the RNIC (100) to a client (200). The onboard memory (105) is operable to provide a buffer (110) for storage of data from a distributed storage system for a read request from the client (200). The trigger control (120) includes a programmable trigger condition. The RNIC (100) is operable to support a speculative read of data in response to a read request snoop of a write of data to the onboard memory (105), and upon detecting the trigger condition, to provide the data in the buffer to the client (200).

Abstract: A system for managing communication with a movable object includes one or more processors configured to receive a request for movable object data from a requester in a movable object environment, determine whether movable object data corresponding to the request is available in a cache associated with a movable object manager, and, in response to determining that the movable object data is available in the cache, provide the movable object data in the cache to the requester.

Abstract: A front-end unit that operates within a C-RAN architecture to perform the functions of cellular signal processing and resource selection between an RRU and the BBU pool network is described. The front-end unit supports flexible load migration and CoMP (coordinated multipoint) in the CRAN BBU while also reducing data transmission within the BBU pool network or between the BBU pool network and the RRU.

Abstract: The invention provides compounds that are inhibitors or covalent modifiers of succinate dehydrogenase subunit B (SDHB) and/or inhibitors of apoptosis, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition.

Abstract: A remote synchronization method includes associating a listening environment with a listen object including status information of a first device, adding a listener to the listening environment that is configured to listen in the listen object, and notifying a second device in response to the listener detecting that the listen object has changed.

Abstract: Described is a system and method for enabling visual search for information. With each selection of an object included in an image, additional images that include visually similar objects are determined and presented to the user.

Abstract: Disclosed is a 2-morpholin-4,6-disubstituted pyrimidine derivative as shown in formula (1) below, and a pharmaceutically acceptable salt, solvate, stereoisomer or prodrug thereof, and a pharmaceutical composition thereof and a use thereof, wherein the definition of each group is as shown in the description. The compound has a PI3K kinase inhibition activity, and has a relatively high inhibitive ability and a low cytotoxicity against PIK3CA mutant breast cancer cell strains T47D and MCF-7.

Abstract: A method includes receiving state information of a virtual movable object in a simulated movement from a movement simulator associated with a movable object and determining movement information for the simulated movement by associating the state information with context information. The state information includes information identifying a location of the virtual movable object in a virtual space. The context information includes information identifying a location of the user terminal, which is at a different location than the movable object in a real space. The method further includes displaying the simulated movement on a display associated with the user terminal based on the movement information, and receiving control data to control the simulated movement in the virtual space using the user terminal when the movable object is in simulation and to control movement of the movable object in the real space when the movable object is in real operation.

Abstract: A method and apparatus for selecting an integrated circuit device neural network modeling sample; for an input variable having the largest mean impact value, by means of continually and equally dividing an interval of the input variable, until relative errors of all divided intervals are equal to or less than a preset error precision, only at which point the equal division action stops, and the length of the divided interval having the smallest length being taken as a step length of the output variable; the step lengths of other input variables then being respectively calculated, according to the step length of the input variable; and finally, for each input variable, points being extracted according to a change interval and the step length thereof, thereby obtaining a sample point set of each input variable.

Abstract: The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.

Abstract: A method for providing flight information related to an unmanned aerial vehicle (UAV) includes receiving, at a remote terminal, UAV state information comprising at least attitude information of the UAV when the UAV is airborne; determining, based on sensing data from one or more sensors of the remote terminal, remote terminal state information; processing the received UAV state information and the remote terminal state information to determine a spatial relationship between the UAV and the remote terminal; and simultaneously displaying, in a same display area on a display of the remote terminal, the determined spatial relationship between the UAV and the remote terminal, and a non-numeric, graphical attitude indicator that indicates the attitude information of the UAV.

Abstract: Method and apparatus of prompting a position of an aerial vehicle are provided. The method may include: obtaining first position information of the aerial vehicle and second position information of a ground end; and presenting a relative position relationship between the aerial vehicle and the ground end on a preset map according to the first position information and the second position information. Flight status including flight position and other suitable information of an aerial vehicle may therefore be directly provided.

Abstract: System and method can support a simulated movement of a movable object, such as a simulated flight of an unmanned aircraft vehicle (UAV). A process, which can be on a user terminal, can receive state information about the simulated flight from a flight simulator that is associated with the UAV. Then, the process can determine flight information for the simulated flight by associating the received state information with context information obtained by the process on the user terminal, and provides the determined flight information to a display that is associated with the user terminal.

Abstract: In the disclosure, a Bluetooth device networking method and system comprises the following steps: the terminal initialization preset all Bluetooth devices within the region, and record all Bluetooth devices corresponding to the identification information of the preset range. When the terminal needs to control the Bluetooth device in the preset area, only the control command information is broadcasted. The Bluetooth device receives the control command information equipment, judgment unit of the Bluetooth device will determine whether the identification information control command information contained in equipment for self-identification information corresponding, if executing the equipment control command information, otherwise it will continue to broadcast the control command information. When Bluetooth device executes the control command information, it broadcasts the response information to the outside, and is finally received by the terminal after being transmitted by Bluetooth network.

Abstract: The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.