Abstract: The invention relates to a method for preparing an anti-counterfeiting modal fiber, including: mixing a pulp stock solution with a cellulose catalyst, alkalizing, aging, sulfonating, and then dissolving the pulp stock solution in an alkaline solution to obtain a treatment solution; mixing the treatment solution with multiple amino acid-metal chelates, filtering, defoaming and ripening to obtain a spinning stock solution; and mixing the spinning stock solution with a spinning bath additive, and wet spinning, followed by drafting, defoaming, desulfurizing, water washing, and other post-treatments, to obtain an anti-counterfeiting modal fiber, wherein the amino acid metal-chelates account for 0.5%-1.5% by weight of the spinning stock solution. Amino acid-metal chelates are used to anti-counterfeit and encrypt the modal fibers, and the anti-counterfeiting and encrypting is involved in the spinning stock solution of modal fibers.

Abstract: Disclosed is a tumor-targeting fusion protein comprising at least (i) a IL-15 peptide or a variant or functional fragment thereof, (ii) a IL-15R? polypeptide or a variant or functional fragment thereof, (iii) a Fc domain or a variant or functional fragment thereof, and (iv) a RGD polypeptide or a variant thereof. The fusion protein is preferably configured as RGD polypeptide-Fc domain-IL-15 polypeptide-IL-15R? polypeptide. The tumor-targeting fusion proteins provided herein improves the anti-tumor effects of IL-15 and prolongs the half-life of IL-15, while targeting tumor sites and acting upon tumor cells. In addition, the fusion proteins are capable of being expressed at high efficiency and purified. The high efficiency of anti-tumor activity enables the fusion proteins to be an excellent candidate for tumor immunotherapy.

Abstract: A photovoltaic energy system and a method for detecting a ground insulation impedance, improve accuracy of detecting a ground insulation impedance after one or more conversion circuits are connected in parallel. The photovoltaic energy system includes one or more conversion circuits and a detection circuit. The detection circuit includes an alternating current signal source and a sampling resistor that are connected in series, a first sampling circuit, and a control circuit. The control circuit is configured to control the alternating current signal source to output harmonic signals of a first frequency and a second frequency. The first sampling circuit is configured to: when the alternating current signal source outputs the harmonic signal of the first frequency, collect a voltage at both terminals of the sampling resistor to obtain a first voltage.

Abstract: Provided herein are organ preservation solutions and methods of use thereof for preserving organs. In particular, provided herein are preservation solutions comprising a mineralocorticoid receptor antagonist, aldehyde dehydrogenase agonist, and/or histone deacetylase inhibitor, and methods of perfusing and storing an organ while awaiting transplantation or non-transplant surgery.

Abstract: The application relates to a sericin protein particle with an oxidative stress property, a method for preparing the same and use thereof. The particle is formed by sericin protein and a tellurium compound. In the method for preparing the sericin protein particle, bis(1-hydroxydodecyl) telluride is first prepared and then mixed with a solution of sericin protein, and a resulting solution is agitated continuously for some time to obtain telluride-modified sericin protein. Then, the solution of the sericin protein is added dropwise into absolute ethanol to obtain a precipitated product. An aqueous solution of the precipitated product and a solution of magnesium ions are mixed and agitated for a certain time to obtain the sericin protein particle with an oxidative stress property. The sericin protein particle disclosed is a hollow particle having a diameter in a range of 600-1250 nm, and is capable of loading biomacromolecule drugs or other components.

Abstract: Disclosed in some examples are memory devices which feature intelligent adjustments to SLC cache configurations that balances memory cell lifetime with performance. The size of the SLC cache can be adjusted during usage of the memory device based upon a write amplification (WA) metric of the memory device. In some examples, the size of the SLC cache can be adjusted during usage of the memory device based upon a write amplification (WA) metric of the memory device and a memory device logical saturation metric (percentage of valid user data written in the device of the total user size).

Abstract: The present invention relates to a scalable process for the making of elagolix, its salts and the process of intermediate compounds.

Abstract: A tri-block copolymer includes a first end block consisting of a hydrophobic, nano-fiber forming polymer, wherein the first end block is present in the tri-block copolymer at a weight percentage ranging from about 10% to about 89%; a middle block attached to the first end block, the middle block consisting of a hydrophilic polymer, wherein the middle block is present in the tri-block copolymer at a weight percentage ranging from about 1% to about 89%; and a second end block attached to the middle block, the second end block consisting of a temperature-responsive polymer, wherein the second end block is present in the tri-block copolymer at a weight percentage ranging from about 1% to about 89%.

Abstract: Devices and techniques for synchronizing NAND logical-to-physical table region tracking are described herein. Table region data structures for physical blocks are maintained. These structures include logical-to-physical (L2P) mapping table portions that point to the respective physical blocks. When garbage collection is performed on a block, table region structures for that block, and another (e.g., the next block to be garbage collected) are read to avoid loading L2P table regions that do not point to the block. If any of the read portions of the L2P table region fail to point to either the block or the other block, these L2P table portions are removed from the loaded table region data structures.

Abstract: A method that includes selectively positioning an ablation catheter system at a treatment site; and ablating tissue at the treatment site with the ablation catheter system using a power setting of approximately 90W applied to tissue for approximately four (4) second increments with a break period of approximately 4 seconds between applications.

Abstract: A probe-type online biomass detection apparatus capable of being subjected to high-temperature sterilization includes an optical fiber probe (1), a light source and light receiving sensor module (2), and a signal processing module (3). A portion, which is required to touch cytosol, of the apparatus adopts a detachable design scheme, to meet requirements for high-temperature sterilization of the probe (1). In the meantime, with regard to influence of bubbles in a fermentation tank on measurement values, a bubble filtering structure is provided, to reduce flow rate and number of the bubbles in the measurement area; and a measurement signal is filtered and optimized through a software algorithm, so that interference of the bubbles is eliminated finally.

Abstract: A semiconductor device includes a semiconductor substrate, a conductive pad over the semiconductor substrate, a conductive bump, a conductive cap over the conductive bump, and a passivation layer. The conductive pad is over the semiconductor substrate. The conductive bump is over the conductive pad, wherein the conductive bump has a stepped sidewall structure including a lower sidewall, an upper sidewall laterally offset from the lower sidewall, and an intermediary surface laterally extending from a bottom edge of the upper sidewall to a top edge of the lower sidewall. The conductive cap is over the conductive bump. The passivation layer is over the semiconductor substrate and laterally surrounds the conductive bump, wherein the passivation layer has a top surface higher than the intermediary surface of the stepped sidewall structure of the conductive bump and lower than a top surface of conductive cap.

Abstract: The present disclosure provides a gamma ray imaging device and an imaging method, where the imaging device includes a plurality of separate detectors. The plurality of separate detectors are provided at an appropriate spatial position, in an appropriate arrangement manner and are of an appropriate detector material, such that when rays emitted from different positions in an imaging area reach at least one of the plurality of separate detectors, at least one of the thicknesses of the detectors, the materials of the detectors, and the numbers of the detectors though which the rays pass are different, thereby achieving the effect of determining the directions of rays.

Abstract: Disclosed is a tumor-targeting fusion protein comprising at least (i) a IL-15 peptide or a variant or functional fragment thereof, (ii) a IL-15R? polypeptide or a variant or functional fragment thereof, (iii) a Fc domain or a variant or functional fragment thereof, and (iv) a RGD polypeptide or a variant thereof. The fusion protein is preferably configured as RGD polypeptide-Fc domain-IL-15 polypeptide-IL-15R? polypeptide. The tumor-targeting fusion proteins provided herein improves the anti-tumor effects of IL-15 and prolongs the half-life of IL-15, while targeting tumor sites and acting upon tumor cells. In addition, the fusion proteins are capable of being expressed at high efficiency and purified. The high efficiency of anti-tumor activity enables the fusion proteins to be an excellent candidate for tumor immunotherapy.

Abstract: The present invention relates to a multi-specific antibody conjugate (such as, a bispecific antibody conjugate), and a related composition, therapeutic method and use thereof. The antibody conjugate comprises a multispecific antibody, such as a bispecific antibody, conjugated to a nanomaterial. The antibody conjugate can be used to modulate an immune response, treat or prevent a disease or condition (e.g., a cancer, autoimmune disease, pathogen infection or inflammatory disease), etc.

Abstract: At least one aspect is directed to improving the performance of real-time verification of online identity. The issuer computing system can receive a request to generate a composite token, the composite token configured to authorize certain verifying parties to authenticate a first-party token comprising information about a client. The issuer can generate a composite token using cryptographic keys and distribute it to the client, who can distribute it to other content item networks. The verifying parties can receive the composite token from the content item networks, use a cryptographic key verify the authenticity of the token corresponding to the client device, and use the token to further process content item operations. The system can distribute the cryptographic keys prior to the generation and verification of the composite token, and as such allow the parties to verify the composite token in real-time without contacting outside verification parties.

Abstract: A semiconductor device comprises a semiconductor substrate, a conductive pad over the semiconductor substrate, a conductive bump over the conductive pad, a conductive cap over the conductive bump, and a passivation layer over the semiconductor substrate and surrounding the conductive bump. A combination of the conductive bump and the conductive cap has a stepped sidewall profile. The passivation layer has an inner sidewall at least partially facing and spaced apart from an outer sidewall of the conductive bump.

Abstract: A method that includes selectively positioning an ablation catheter system at a treatment site; and ablating tissue at the treatment site with the ablation catheter system using a power setting of approximately 90 W applied to tissue for approximately four (4) second increments with a break period of approximately 4 seconds between applications.