Abstract: The present disclosure relates to a wide-range perpendicular sensitive magnetic sensor and the method for manufacturing the same, the magnetic sensor includes a substrate, a plurality of magnetic tunnel junctions, a plurality of magnetic flux regulators, a first output port and a second output port.

Abstract: The present disclosure relates to a wide-range perpendicular sensitive magnetic sensor and the method for manufacturing the same, the magnetic sensor includes a substrate, a plurality of magnetic tunnel junctions, a plurality of magnetic flux regulators, a first output port and a second output port.

Abstract: A current sensor includes: four first uniaxial TMR chips and at least two second uniaxial TMR chips, each first uniaxial TMR chip and each second uniaxial TMR chip being located on the same virtual ring, wherein magnetic sensitive directions of the four first uniaxial TMR chips are perpendicular to a radius of the virtual ring, magnetic sensitive directions of two adjacent first uniaxial TMR chips are perpendicular to each other, magnetic sensitive directions of the two second uniaxial TMR chips are parallel to the radius of the virtual ring and opposite to each other, and the two second uniaxial TMR chips respectively have the same positions as two first uniaxial TMR chips; each first uniaxial TMR chip and each second uniaxial TMR chip are configured to collect a magnetic induction intensity, the magnetic induction intensity is configured to calculate a target current value of a to-be-measured wire.

Abstract: The present disclosure relates to an AC/DC closed-loop current sensor, including a magnetism gathering iron core, a TMR chip, a signal processing circuit, a signal generator, and a feedback coil. The TMR chip is arranged at an air gap of the magnetism gathering iron core and connected to the signal processing circuit. The signal processing circuit is connected to the signal generator. The feedback coil is wound around the magnetism gathering iron core and connected to the signal generator. The signal processing circuit is configured to select from the induced signal of the TMR chip and make an amplification to obtain a current signal component and send the current signal component to the signal generator. The signal generator is configured to adjust a current output to the feedback coil based on the current signal component, and output a measurement result of the selected current signal component.

Abstract: The present disclosure provides a Cellulosimicrobium cellulans strain and use thereof in straw field composting, belonging to the technical field of microorganisms. In the present disclosure, the Cellulosimicrobium cellulans strain is named Cellulosimicrobium cellulans MC29-GFP, and is deposited in the China General Microbiological Culture Collection Center (CGMCC), with a deposit number of CGMCC No. 25013. The Cellulosimicrobium cellulans MC29-GFP can promote the compost decomposition of straw in field. The experimental results show that the Cellulosimicrobium cellulans MC29-GFP significantly increases activities of cellulase and peroxidase in the straw during the decomposition compared with Bacillus amyloliquefaciens SQR9, thereby achieving rapid decomposition.

Abstract: The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.

Abstract: The present disclosure relates to novel lymphoid-specific tyrosine phosphatase (LYP, encoded by the PTPN22 gene) inhibitors, and to methods of making and using the novel LYP inhibitors. Thus, the compounds according to the disclosure may be used for treating diseases or disorders associated with PTPN22 genetic polymorphism, including type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosis, Graves' disease, Addison's disease, vitiligo, juvenile arthritis, Hashimoto thyroiditis, and other rarer diseases. Furthermore, these LYP inhibitors may be served for a novel class of cancer immunotherapy. The compounds can be injected or orally administered.

Abstract: An automated process for separating and recycling a broad mix of waste material including industrial and commercial streams. The process begins by collecting the broad mix of waste material. Optionally, the broad mix of waste material is sorted to remove contamination from the broad mix of waste material. Next, the broad mix of waste material is coarsely shredded. Plastic film is removed from the broad mix of waste material, creating a stream of plastic film and a separate stream of dirty cardboard. Residual plastic is separated from the cardboard stream and included either in the plastic stream or in an independent third stream. The process yields separate streams of a film-rich recycled plastic and a clean recycled cardboard having a purity of at least about 95%. Also provided are a related system and at least one computer-readable non-transitory storage medium embodying software for performing the process.

Abstract: The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.

Abstract: The present disclosure discloses a combustion chamber and a combustion apparatus. The combustion chamber includes: a first surrounding plate located on an outer side and a second surrounding plate located on an inner side. A combustion cavity is defined by the second surrounding plate. The first surrounding plate and the second surrounding plate are spaced apart from each other to define at least one air duct in communication with the combustion cavity. Each of the at least one air duct has an air inlet hole formed in the first surrounding plate, and an air outlet hole formed in the second surrounding plate.

Abstract: The present disclosure relates to novel N-aryl oxamic acid based inhibitors for Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB), and to the method of making and using the novel N-aryl oxamic acid based inhibitors. More specifically, compounds provided in this disclosure can be used to inhibit Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB) and to treat a patient having a Tuberculosis disease.

Abstract: The present disclosure relates to novel lymphoid-specific tyrosine phosphatase (LYP, encoded by the PTPN22 gene) inhibitors, and to methods of making and using the novel LYP inhibitors. Thus, the compounds according to the disclosure may be used for treating diseases or disorders associated with PTPN22 genetic polymorphism, including type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosis, Graves' disease, Addison's disease, vitiligo, juvenile arthritis, Hashimoto thyroiditis, and other rarer diseases. Furthermore, these LYP inhibitors may be served for a novel class of cancer immunotherapy. The compounds can be injected or orally administered.

Abstract: The present disclosure relates to novel N-aryl oxamic acid based inhibitors for Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB), and to the method of making and using the novel N-aryl oxamic acid based inhibitors. More specifically, compounds provided in this disclosure can be used to inhibit Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB) and to treat a patient having a Tuberculosis disease.

Abstract: The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging thugs for cancers.

Abstract: The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.

Abstract: Small molecule compounds derived from ?-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB, LMWPTP, and Laforin. Use of these compounds as pharmaceutical agents for treating diseases associated with abnormal protein tyrosine phosphatase activity is also provided.

Abstract: Small molecule compounds derived from ?-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB, LMWPTP, and Laforin. Use of these compounds as pharmaceutical agents for treating diseases associated with abnormal protein tyrosine phosphatase activity is also provided.

Abstract: Embodiments of the present disclosure disclose an interactive method, a client device, a mobile terminal and a server, which relate to an Internet technology field and provide a new way for interacting with a user. The interactive method provided by the present disclosure includes: sending a first request of obtaining first activity information to a server, such that the server obtains the first activity information in local according to the first request of obtaining first activity information, the first activity information comprising an activity entrance icon; receiving the first activity information returned by the server; displaying the activity entrance icon on a user interface of the client device according to the first activity information; receiving an activity participating instruction issued by a user through operating the activity entrance icon; popping up an activity participating result according to the activity participating instruction.

Abstract: Embodiments of the present disclosure disclose an interactive method, a client device, a mobile terminal and a server, which relate to an Internet technology field and provide a new way for interacting with a user. The interactive method provided by the present disclosure includes: sending a first request of obtaining first activity information to a server, such that the server obtains the first activity information in local according to the first request of obtaining first activity information, the first activity information comprising an activity entrance icon; receiving the first activity information returned by the server; displaying the activity entrance icon on a user interface of the client device according to the first activity information; receiving an activity participating instruction issued by a user through operating the activity entrance icon; popping up an activity participating result according to the activity participating instruction.

Abstract: Methods are disclosed herein for administering a oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitor for treating autoimmune and/or glomerulonephritis-associated diseases, and in particular, Systemic Lupus Erythematosus (SLE).