Patents by Inventor Zhuhui Huang

Zhuhui Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant newcastle disease viruses useful as vaccines or vaccine vectors
    Patent number: 9476033
    Abstract: The present invention concerns an antigenomic RNA of Newcastle Disease virus (NDV) carrying one or more foreign genes inserted before NP gene, between P and M genes, and/or between HN and L genes. The invention is also directed toward a cDNA encoding a recombinant antigenomic RNA having one or more foreign genes inserted according to the invention, a cell containing the cDNA, a plasmid comprising the cDNA, a cell containing the plasmid, a cell containing the recombinant antigenomic RNA, and a recombinant NDV containing the recombinant antigenomic RNA of the invention, such as a recombinant NDV carrying one or more foreign genes recovered from transcription of the cDNA or the plasmid in a competent cell. The recombinant NDV carrying the one or more foreign genes can be used as a vaccine or vaccine vector.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: October 25, 2016
    Assignee: The University of Maryland, College Park
    Inventors: Siba K. Samal, Zhuhui Huang
  • RECOMBINANT NEWCASTLE DISEASE VIRUSES USEFUL AS VACCINES OR VACCINE VECTORS
    Publication number: 20120064112
    Abstract: The present invention concerns an antigenomic RNA of Newcastle Disease virus (NDV) carrying one or more foreign genes inserted before NP gene, between P and M genes, and/or between HN and L genes. The invention is also directed toward a cDNA encoding a recombinant antigenomic RNA having one or more foreign genes inserted according to the invention, a cell containing the cDNA, a plasmid comprising the cDNA, a cell containing the plasmid, a cell containing the recombinant antigenomic RNA, and a recombinant NDV containing the recombinant antigenomic RNA of the invention, such as a recombinant NDV carrying one or more foreign genes recovered from transcription of the cDNA or the plasmid in a competent cell. The recombinant NDV carrying the one or more foreign genes can be used as a vaccine or vaccine vector.
    Type: Application
    Filed: July 21, 2011
    Publication date: March 15, 2012
    Applicant: THE UNIVERSITY OF MARYLAND, COLLEGE PARK
    Inventors: SIBA K. SAMAL, ZHUHUI HUANG
  • Recombinant Newcastle disease viruses useful as vaccines or vaccine vectors
    Publication number: 20030224017
    Abstract: The present invention concerns an antigenomic RNA of Newcastle Disease virus (NDV) carrying one or more foreign genes inserted before NP gene, between P and M genes, and/or between HN and L genes. The invention is also directed toward a cDNA encoding a recombinant antigenomic RNA having one or more foreign genes inserted according to the invention, a cell containing the cDNA, a plasmid comprising the cDNA, a cell containing the plasmid, a cell containing the recombinant antigenomic RNA, and a recombinant NDV containing the recombinant antigenomic RNA of the invention, such as a recombinant NDV carrying one or more foreign genes recovered from transcription of the cDNA or the plasmid in a competent cell. The recombinant NDV carrying the one or more foreign genes can be used as a vaccine or vaccine vector.
    Type: Application
    Filed: May 19, 2003
    Publication date: December 4, 2003
    Inventors: Siba K. Samal, Zhuhui Huang