Patents by Inventor Ziyang Zhang

Ziyang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11008358
    Abstract: The present invention provides desosamine and mycaminose analogs and nitro sugars and methods for their preparation. The invention also provides methods of cyclizing a compound of Formula (A?) with glyoxal to give a nitro sugar of Formula (B). Methods for the preparation of compound of Formula (D?) are provided comprising cyclization of a nitro alcohol to give a nitro sugar and reduction and alkylation of the nitro sugar to give a desosamine, mycaminose, or an analog thereof.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: May 18, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Ziyang Zhang
  • Patent number: 11004893
    Abstract: A photonic integrated device is provided, includes a substrate, a two-dimensional material unit and semiconductor light-emitting units located at both sides thereof are disposed on the substrate; the two-dimensional material unit is provided with a luminescent two-dimensional material of which a luminous band is longer than that of the semiconductor light-emitting unit, and the semiconductor light-emitting unit provides a pump light source for the two-dimensional material unit to pump the luminescent two-dimensional material to emit light. The photonic integrated device in the present disclosure can obtain different luminous bands by changing the number of layers or kinds of the luminescent two-dimensional material.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: May 11, 2021
    Assignee: QINGDAO YICHENLEISHUO TECHNOLOGY CO., LTD
    Inventors: Ziyang Zhang, Hongmei Chen, Yuanqing Huang, Qinglu Liu
  • Publication number: 20210071917
    Abstract: A solid-state heat transporting device including a heat transporting element whose uniformity of contact with one or multiple surfaces is controllable so that various amounts of heat may be transported to and from the one or multiple surfaces. The heat transporting element uses the electrocaloric effect to absorb and release the heat and the uniformity of contact is controlled using an electrostatic effect which may change the shape of the heat transporting element. In one embodiment, the heat transporting element is an electrostatically actuated P(VDF-TrFE-CFE) polymer stack achieving a high specific cooling power of 2.8 W/g and a COP of 13 (the highest reported coefficient of performance to date) when used as a cooling device.
    Type: Application
    Filed: May 7, 2018
    Publication date: March 11, 2021
    Applicants: The Regents of the University of California, SIR International
    Inventors: Qibing Pei, Rujun Ma, Ziyang Zhang, Roy Kornbluh, David Huber
  • Patent number: 10913764
    Abstract: Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: February 9, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Ian Bass Seiple, Ziyang Zhang
  • Publication number: 20210025626
    Abstract: In an embodiment of the invention, the device comprises a bottom electrode on a substrate and a top electrode on a substrate separated by a fixed distance from each other. Semi-insulator layers with proper electrical conductivity are attached to the bottom and top electrodes. Disposed between the substrates is a flexible S-shaped polymer stack having electrode layers with one end of the stack attached to the top substrate and the other end in contact with the bottom substrate. When a voltage is applied between the stack and the electrode layer on the bottom substrate, the stack is induced by electrostatic force to deflect in a rolling wave-like motion.
    Type: Application
    Filed: March 25, 2019
    Publication date: January 28, 2021
    Applicant: The Regents of the University of California
    Inventors: Qibing Pei, Rujun Ma, Ziyang Zhang
  • Publication number: 20200377542
    Abstract: Provided herein are macrolide compounds of Formula (I) and (I-N) for the treatment of infectious diseases and inflammatory conditions. The 14-membered ketolides and 14-, 15-, and 16-membered azaketolides described herein comprise modified sugars which are desosamine or mycaminose analogs. Pharmaceutical compositions and methods of treating infection diseases and inflammatory conditions using the inventive macrolides are also provided. This disclosure additionally provides methods of preparing the macrolides by the coupling of an eastern and western half.
    Type: Application
    Filed: April 8, 2020
    Publication date: December 3, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Ian Bass Seiple, Ziyang Zhang
  • Publication number: 20200361980
    Abstract: Provided herein are methods of preparing new 14-membered ketolides via coupling of an eastern and western half moiety, followed by macrocyclization, and optional functionalization. Intermediates in the synthesis of these ketolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using these ketolides are also provided.
    Type: Application
    Filed: April 8, 2020
    Publication date: November 19, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Ian Bass Seiple, Ziyang Zhang
  • Publication number: 20200354900
    Abstract: A method for permeable pavement of dirt interception comprises laying a permeable structure layer with a toothed groove between the base layer and the transition surface of the cushion layer or directly setting the upper surface of the cushion layer as a toothed structure; in the base layer, laying at least one layer of dirt interception trough; providing a water-permeable coating or fine sand at the bottom of the sewage interception trough; the present invention traps the dirt between the base layer and the cushion layer that are most likely to cause void blocking in the base layer, close to the shallow part of the surface layer is used to remove dirt by high-pressure flushing operations.
    Type: Application
    Filed: March 4, 2020
    Publication date: November 12, 2020
    Applicant: Beijing University of Civil Engineering and Architecture
    Inventors: Haiyan LI, Zhichao YANG, Yan HUANG, Liyuan WU, Xiaoran ZHANG, Ziyang ZHANG, Jinxi LI
  • Publication number: 20200347087
    Abstract: The present invention provides desosamine and mycaminose analogs and nitro sugars and methods for their preparation. The invention also provides methods of cyclizing a compound of Formula (A?) with glyoxal to give a nitro sugar of Formula (B). Methods for the preparation of compound of Formula (D?) are provided comprising cyclization of a nitro alcohol to give a nitro sugar and reduction and alkylation of the nitro sugar to give a desosamine, mycaminose, or an analog thereof.
    Type: Application
    Filed: December 23, 2019
    Publication date: November 5, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Ziyang Zhang
  • Publication number: 20200181815
    Abstract: The present invention provides a method of manufacturing and an application of body smoothing knitted underwear capable of being used as an outerwear. The method includes the following steps: raw material preparation, knitting, dyeing, setting, cutting and sewing, bonding, ironing and finishing. The method can be realized by using the existing combined cylinder knitting device. Through the innovation of raw materials and processes, the underwear produced is soft, comfortable, breathable and warm, and has modest elasticity and the body smoothing function, which can tighten the skin. It is beautiful and elegant, and suitable for outside wearing as well.
    Type: Application
    Filed: February 2, 2019
    Publication date: June 11, 2020
    Inventor: Ziyang Zhang
  • Patent number: 10665749
    Abstract: The present disclosure discloses a manufacturing method of a quantum dot structure including: providing a quantum dot film layer on a substrate; providing a first protection film on the quantum dot film layer; providing a patterned array on the first protection film; providing a second protection film on the first protection film and the patterned array to obtain an intermediate body; and performing an annealing process on the intermediate body to obtain the quantum dot structure on the substrate.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: May 26, 2020
    Assignee: QINGDAO YICHENLEISHUO TECHNOLOGY CO., LTD
    Inventors: Ziyang Zhang, Rong Huang, Yuanqing Huang
  • Patent number: 10640528
    Abstract: Provided herein are macrolide compounds of Formula (I) and (I-N) for the treatment of infectious diseases and inflammatory conditions. The 14-membered ketolides and 14-, 15-, and 16-membered azaketolides described herein comprise modified sugars which are desosamine or mycaminose analogs. Pharmaceutical compositions and methods of treating infection diseases and inflammatory conditions using the inventive macrolides are also provided. This disclosure additionally provides methods of preparing the macrolides by the coupling of an eastern and western half.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: May 5, 2020
    Assignee: President and Fellows of Havard College
    Inventors: Andrew G. Myers, Ian Bass Seiple, Ziyang Zhang
  • Patent number: 10633407
    Abstract: Provided herein are methods of preparing new 14-membered ketolides via coupling of an eastern and western half moiety, followed by macro-cyclization, and optional functionalization. Intermediates in the synthesis of these ketolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using these ketolides are also provided.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: April 28, 2020
    Assignee: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Ian Bass Seiple, Ziyang Zhang
  • Publication number: 20200098820
    Abstract: A photonic integrated device is provided, includes a substrate, a two-dimensional material unit and semiconductor light-emitting units located at both sides thereof are disposed on the substrate; the two-dimensional material unit is provided with a luminescent two-dimensional material of which a luminous band is longer than that of the semiconductor light-emitting unit, and the semiconductor light-emitting unit provides a pump light source for the two-dimensional material unit to pump the luminescent two-dimensional material to emit light. The photonic integrated device in the present disclosure can obtain different luminous bands by changing the number of layers or kinds of the luminescent two-dimensional material.
    Type: Application
    Filed: December 29, 2016
    Publication date: March 26, 2020
    Applicant: QINGDAO YICHENLEISHUO TECHNOLOGY CO,.LTD
    Inventors: Ziyang ZHANG, Hongmei CHEN, Yuanqing HUANG, Qinglu LIU
  • Publication number: 20200059093
    Abstract: Disclosed are a dynamic lightning protection method and system. The method includes detecting lightning in real time and tracking a position of a thunderstorm; and performing dynamic lightning protection and control on an electrical grid according to an electrical grid control strategy before the thunderstorm reaches or affects the electrical grid. Further disclosed is a dynamic lightning protection system.
    Type: Application
    Filed: July 13, 2018
    Publication date: February 20, 2020
    Inventors: Chong TONG, Yunfeng CAI, Ziyang ZHANG, Qing WANG, Kang DAI, Wei YIN
  • Patent number: 10544182
    Abstract: The present invention provides desosamine and mycaminose analogs and nitro sugars and methods for their preparation. The invention also provides methods of cyclizing a compound of Formula (A?) with glyoxal to give a nitro sugar of Formula (B). Methods for the preparation of compound of Formula (D?) are provided comprising cyclization of a nitro alcohol to give a nitro sugar and reduction and alkylation of the nitro sugar to give a desosamine, mycaminose, or an analog thereof.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: January 28, 2020
    Assignee: Presidents and Fellow of Harvard College
    Inventors: Andrew G. Myers, Ziyang Zhang
  • Publication number: 20200028026
    Abstract: The present disclosure discloses a manufacturing method of a quantum dot structure including: providing a quantum dot film layer on a substrate; providing a first protection film on the quantum dot film layer; providing a patterned array on the first protection film; providing a second protection film on the first protection film and the patterned array to obtain an intermediate body; and performing an annealing process on the intermediate body to obtain the quantum dot structure on the substrate.
    Type: Application
    Filed: December 30, 2016
    Publication date: January 23, 2020
    Applicant: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO), CHINESE ACADEMY OF SCIENCES
    Inventors: Ziyang ZHANG, Rong HUANG, Yuanqing HUANG
  • Publication number: 20190271899
    Abstract: The present disclosure discloses a saturable absorber mirror of a composite structure, including: a substrate; a buffer layer on the substrate; a distributed Bragg reflective mirror on the buffer layer; a quantum dot or quantum well saturable absorber body on the distributed Bragg reflective mirror; a graphene saturable absorber body on the quantum dot or quantum well saturable absorber body. In the present disclosure, the graphene saturable absorber body is composited with the quantum dot saturable absorber body or the quantum well saturable absorber body to be used as the saturable absorber body in the saturable absorber mirror of the present disclosure. A thermal damage threshold and an optical property stability of the saturable absorber body are improved, and an ultrafast laser pulse with high power and short pulse mode locking, a stable output repetition cycle, a narrow pulse width, and a short response time is implemented.
    Type: Application
    Filed: December 27, 2016
    Publication date: September 5, 2019
    Applicant: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS(SINANO), CHINESE ACADEMY OF SCIENCES
    Inventors: Ziyang ZHANG, Qinglu LIU
  • Patent number: 10372956
    Abstract: Provided is a method for doing business, which comprises the steps of providing an indicia reader at a point of transaction (POT), capturing a digital image with the indicia reader at the POT and archiving the digital image.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: August 6, 2019
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Xiaoxun Zhu, Ziyang Zhang
  • Publication number: 20180298048
    Abstract: Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided.
    Type: Application
    Filed: April 5, 2018
    Publication date: October 18, 2018
    Applicant: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Ian Bass Seiple, Ziyang Zhang