BIOSENSOR
Disclosed is a biosensor, including: a biochip to which a probe molecule is fixed on a wall thereof and into which a target molecule is injected; and a capacitive touch panel for detecting a reaction of the probe molecule in the biochip and the injected target molecule.
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This application is based on and claims priority from Korean Patent Application No. 10-2011-0051174, filed on May 30, 2011, with the Korean Intellectual Property Office, the present disclosure of which is incorporated herein in its entirety by reference.
TECHNICAL FIELDThe present disclosure relates to a biosensor, and more particularly, to a biosensor which detects a biomaterial on a biochip by using a touch panel of a mobile device driven in a capacitive manner.
BACKGROUNDMost biosensors for detecting a specific target molecule (for example, protein, enzyme, and DNA) contained in a liquid biosample have a probe molecule fixed on a surface of a sensing part, and such a probe molecule is particularly bonded only to a specific target molecule to allow selective detection of a biomaterial.
Sensors for quantitatively detecting a bond between a target molecule and a probe molecule may be classified into optical sensors and electrical sensors. An optical sensor marks a light emitting material such as a fluorescent material, a phosphorescent material, and a color material on a target molecule bonded to a probe molecule on a sensing part and then detects an optical signal generated from the light emitting material. An electrical sensor fixes a probe molecule on a channel surface of a field effect transistor, and detects a channel current change due to charges of the target molecule generated when a target molecule is coupled to the fixed probe molecule.
The technologies according to the related art require a separate analysis apparatus for detecting and measuring a converted signal in addition to a sensing part for converting a bond of a target molecule and a probe molecule to an optical or electrical signal. That is, an optical sensor requires a large-scale analysis device equipped with an expensive optical system such as an optical scanner to detect a signal of a light emitting marker, and an electrical sensor requires a measuring unit for measuring a minute current change of several nA to several tens of nA at a high signal to noise ratio.
That is, the biosensor according to the related art inevitably requires a separate reader including a signal detecting/processing unit and an external display in addition to a sensing part, and it is difficult to implement such a reader with a portable and inexpensive system, which causes problems in terms of convenience, usability by a user, prompt diagnosis, and costs.
Meanwhile, there have been attempts to process and display a signal sensed by an external signal detector through a mobile device to improve the convenience and approach of a user, in which case an external signal detector is necessary to send and receive data through a wired or wireless communication with the mobile device.
SUMMARYThe present disclosure has been made in an effort to provide a new biosensor which can detect a biomaterial on a biochip by using a touch panel of a mobile device driven in a capacitive manner without using a separate analysis apparatus anywhere and anytime.
An exemplary embodiment of the present disclosure provides a biosensor, including: a biochip to which a probe molecule is fixed on a wall thereof and into which a target molecule is injected; and a capacitive touch panel for detecting a reaction of the probe molecule in the biochip and the injected target molecule.
As described above, the present disclosure provides a biosensor which detects a biomaterial on a biochip by using a touch panel of a mobile device, allowing a user to confirm an analysis result promptly and conveniently anytime and anywhere and reducing costs for manufacturing and managing a separate reader.
The structure of the used biochip is also very simple, making it possible to produce a product at a low price, easily manufacture a product in a form of an array to allow easy expansion of the product, and make the product disposable.
The foregoing summary is illustrative only and is not intended to be in any way limiting. In addition to the illustrative aspects, embodiments, and features described above, further aspects, embodiments, and features will become apparent by reference to the drawings and the following detailed description.
In the following detailed description, reference is made to the accompanying drawing, which form a part hereof. The illustrative embodiments described in the detailed description, drawing, and claims are not meant to be limiting. Other embodiments may be utilized, and other changes may be made, without departing from the spirit or scope of the subject matter presented here.
Hereinafter, an exemplary embodiment of the present disclosure will be described in detail with reference to the accompanying drawings. In the description of the present disclosure, a detailed description of known configurations and functions may be omitted to avoid obscure understanding of the present disclosure.
A biosensor according to the present disclosure is an apparatus which, when a touch panel of a mobile device driven in a capacitive manner contacts a portion of a human body (for example, a hand), detects a change in an electrostatic capacity externally generated when a desired target molecule is bonded to a probe molecule by using a principle where an entire electrostatic capacity change due to an electrostatic capacity of the human body is recognized by the mobile device in order to easily detect a biomaterial only with a biochip itself without using a special attachable device.
As shown in
Meanwhile, as illustrated in
As illustrated in
Referring to
In the biosensor according to the present disclosure, as an equivalent capacitor of a human body capacitor 440 having a capacitance of a finger which is a contact portion of the human body is inserted into the biochip 430, a biomaterial can be analyzed even when the biochip 430 does not contact the finger.
The biochip 430 may be designed to cause a change in electrostatic capacity according to a degree of reaction. Then, a degree of reaction in the biochip 430 is quantified according to the charging time.
Referring to
Accordingly, the biosensor according to the present disclosure can easily detect a biomaterial by, after injecting a target molecule of, for example, blood, body fluid, and urine into a biochip to which inner wall a probe molecule is fixed and reacting the injected target molecule with the probe molecule, placing the biochip on a surface of a touch panel of a mobile device. A structure of the biochip is very simple and low-priced, making it easier to make the biochip disposable.
From the foregoing, it will be appreciated that various embodiments of the present disclosure have been described herein for purposes of illustration, and that various modifications may be made without departing from the scope and spirit of the present disclosure. Accordingly, the various embodiments disclosed herein are not intended to be limiting, with the true scope and spirit being indicated by the following claims.
Claims
1. A biosensor, comprising:
- a biochip to which a probe molecule is fixed on a wall thereof and into which a target molecule is injected; and
- a capacitive touch panel for detecting a reaction of the probe molecule in the biochip and the injected target molecule.
2. The biosensor of claim 1, wherein a resistance of the biochip is varied according to the reaction of the probe molecule and the injected target molecule.
3. The biosensor of claim 2, wherein the biochip represents a change in resistance according to the reaction of the probe molecule and the injected target molecule due to irradiated light.
4. The biosensor of claim 1, wherein an electrostatic capacity of the biochip changes according to the reaction of the probe molecule and the injected target molecule.
5. The biosensor of claim 4, wherein a degree of reaction of the biochip is quantified according to a charging time.
6. The biosensor of claim 1, further comprising:
- a switch located between the biochip and the touch panel.
7. The biosensor of claim 6, wherein the switch is switched by light generated by a liquid crystal display (LCD) of the touch panel.
Type: Application
Filed: May 18, 2012
Publication Date: Dec 6, 2012
Applicant: Electronics and Telecommunications Research Institute (Daejeon)
Inventor: Chang Geun AHN (Daejeon)
Application Number: 13/475,845
International Classification: G06F 3/044 (20060101); G09G 3/36 (20060101);