Apparatus for patterning cells
Latest MedTrain Technologies, LLC Patents:
- Thermally induced gelation of collagen hydrogel and method of thermally inducing gelling a collagen hydrogel
- Thermally induced gelation of collagen hydrogel and method of thermally inducing gelling a collagen hydrogel
- Thermally induced gelation of collagen hydrogel and method of thermally inducing gelling a collagen hydrogel
- Thermally Induced Gelation Of Collagen Hydrogel And Method Of Thermally Inducing Gelling A Collagen Hydrogel
- Apparatus for patterning cells
The broken lines in
Claims
The ornamental design for an apparatus for patterning cells, as shown and described.
2521475 | September 1950 | Nickolas |
D239548 | April 1976 | Schiff et al. |
4087327 | May 2, 1978 | Feder et al. |
4228243 | October 14, 1980 | Iizuka |
4623355 | November 18, 1986 | Sawruk |
4642220 | February 10, 1987 | Bjorkman |
4695547 | September 22, 1987 | Hilliard et al. |
4789601 | December 6, 1988 | Banes |
4822741 | April 18, 1989 | Banes |
4831869 | May 23, 1989 | Fowler et al. |
4839280 | June 13, 1989 | Banes |
4839292 | June 13, 1989 | Cremonese |
4851354 | July 25, 1989 | Winston et al. |
4908319 | March 13, 1990 | Smyczek et al. |
4940853 | July 10, 1990 | Vandenburgh |
4974952 | December 4, 1990 | Focht |
5153136 | October 6, 1992 | Vandenburgh |
5240854 | August 31, 1993 | Berry et al. |
5273905 | December 28, 1993 | Muller et al. |
5348879 | September 20, 1994 | Shapiro et al. |
5414556 | May 9, 1995 | Focht |
5460945 | October 24, 1995 | Springer et al. |
5496697 | March 5, 1996 | Parce et al. |
5518909 | May 21, 1996 | Banes |
5686303 | November 11, 1997 | Korman |
5843766 | December 1, 1998 | Applegate et al. |
D411308 | June 22, 1999 | Pandey et al. |
5958760 | September 28, 1999 | Freeman |
6015590 | January 18, 2000 | Suntola et al. |
6037141 | March 14, 2000 | Banes |
6048723 | April 11, 2000 | Banes |
6207451 | March 27, 2001 | Dennis et al. |
6218178 | April 17, 2001 | Banes |
6472202 | October 29, 2002 | Banes |
6586235 | July 1, 2003 | Banes |
6645759 | November 11, 2003 | Banes |
D500426 | January 4, 2005 | Newman |
6998265 | February 14, 2006 | Banes |
D522145 | May 30, 2006 | Best et al. |
7186548 | March 6, 2007 | Li |
7738682 | June 15, 2010 | Banes et al. |
D632386 | February 8, 2011 | Chang |
D650295 | December 13, 2011 | Schmitz |
D651524 | January 3, 2012 | Kerr |
D688570 | August 27, 2013 | Logue |
D697073 | January 7, 2014 | Andersson et al. |
D708760 | July 8, 2014 | Smeja |
8777013 | July 15, 2014 | Jalindre |
D720844 | January 6, 2015 | Wells |
D736403 | August 11, 2015 | Hudson et al. |
D754840 | April 26, 2016 | Waldman et al. |
D767163 | September 20, 2016 | Schimmel et al. |
D793258 | August 1, 2017 | Buber |
D828122 | September 11, 2018 | Levine |
D873660 | January 28, 2020 | Akana |
20040142411 | July 22, 2004 | Kirk et al. |
20050153273 | July 14, 2005 | Wikswo et al. |
20060270023 | November 30, 2006 | LeDuc et al. |
20070077653 | April 5, 2007 | Banes et al. |
20130337565 | December 19, 2013 | Banes et al. |
2155948 | October 1985 | GB |
- Andarawis-Puri et al., “Rotator cuff tendon strain correlates with tear propagation”, Journal of Biomechanics, 2009, pp. 158-163, vol. 42, No. 2.
- Banes et al., “Mechanical forces and signaling in connective tissue cells: cellular mechanisms of detection, transduction, and responses to mechanical deformation”, Current Opinion in Orthopaedics, 2001, pp. 389-396, vol. 12, No. 5.
- Clark et al., “Integrins and Signal Transduction Pathways: The Road Taken”, Science, 1995, pp. 233-239, vol. 268, No. 5208.
- Di Carlo et al., “Single-Cell Enzyme Concentrations, Kinetics, and Inhibition Analysis Using High-Density Hydrodynamic Cell Isolation Arrays”, Analytical Chemistry, 2006, pp. 4925-4930, vol. 78, No. 14.
- Discher et al., “Tissue Cells Feel and Respond to the Stiffness of Their Substrate”, Science, 2005, pp. 1139-1143, vol. 310, No. 5751.
- Duncan et al., “Mechanotransduction and the Functional Response of Bone to Mechanical Strain”, Calcified Tissue International, 1995, pp. 344-358, vol. 57.
- Howard et al., “Mechanoelectrical Transduction by Hair Cells”, Annual Reviews of Biophysics and Biophysical Chemistry, 1988, pp. 99-124, vol. 17.
- Hellmich et al., “Single cell manipulation, analytics and label-free protein detection in microfluidic devices for systems nanobiology”, Electrophoresis, 2005, pp. 3689-3696, vol. 26, No. 19.
- Irimia et al., “Single-Cell Chemical Lysis in Picoliter-Scale Closed Volumes Using a Microfabricated Device”, Analytical Chemistry, 2004, pp. 6137-6143, vol. 76, No. 20.
- Irimia et al., “Cell Handling using microstructured membranes”, Lab on a Chip, 2006, pp. 345-352, vol. 6, No. 3.
- Li et al., “Biology on a chip: Microfabrication for Studying the Behavior of Cultured Cells”, Critical Reviews in Biomedical Engineering, 2003, pp. 423-488, vol. 31, Nos. 5 & 6.
- Long et al., “Low magnitude of tensile strain inhibits IL-1beta-dependent induction of pro-inflammatory cytokines and induces synthesis of IL-10 in human periodontal ligament cells in vitro”, Journal of Dental Research, 2001, pp. 1416-1420, vol. 80, No. 5.
- Long et al., “Tumor Necrosis Factor alpha-dependent Proinflammatory Gene Induction Is Inhibited by Cyclic Tensile Strain in Articular Chondrocytes In Vitro”, Arthritis & Rheumatism, 2001, pp. 2311-2319, vol. 44, No. 10.
- Martini et al., “Systems Nanobiology: From Quantitative Single Molecule Biophysics to Microfluidic-based Single Cell Analysis”, Sub-cellular Biochemistry, 2007, Chapter 14, pp. 301-321.
- McClain et al., “Microfluidic Devices for the High-Throughput Chemical Analysis of Cells”, Analytical Chemistry, 2003, pp. 5646-5655, vol. 75, No. 21.
- Mijatovic et al., “Technologies for nanofluidic systems: top-down vs. bottom-up—a review”, Lab on a Chip, 2005, pp. 492-500, vol. 5, No. 5.
- Munce et al., “Microfabricated System for Parallel Single-Cell Capillary Electrophoresis”, Analytical Chemistry, 2004, pp. 4983-4989, vol. 76, No. 17.
- Muñoz-Pinedo et al., “Confocal restricted-height imaging of suspension cells (CRISC) in a PDMS microdevice during apoptosis”, Lab on a Chip, 2005, pp. 628-633, vol. 5, No. 6.
- Nevill et al., “Integrated microfluidic cell culture and lysis on a chip”, Lab on a Chip, 2007, pp. 1689-1695, vol. 7, No. 12.
- Ostuni et al., “Patterning Mammalian Cells Using Elastomeric Membranes”, Langmuir, 2000, pp. 7811-7819, vol. 16.
- Quake et al., “From Micro- to Nanofabrication with Soft Materials”, Science, 2000, pp. 1536-1540, vol. 290, No. 5496.
- Reyes et al., “Micro Total Analysis Systems. 1. Introduction, Theory, and Technology”, Analytical Chemistry, 2002, pp. 2623-2636, vol. 74, No. 12.
- Riveline et al., “Focal Contacts as Mechanosensors: Externally Applied Local Mechanical Force Induces Growth of Focal Contacts by an mDia1-dependent and ROCK-independent Mechanism”, Journal of Cell Biology, 2001, pp. 1175-1185, vol. 153, No. 6.
- Ros et al., “Bioanalysis in structured microfluidic systems”, Electrophoresis, 2006, pp. 2651-2658, vol. 27, No. 13.
- Sims et al., “Analysis of single mammalian cells on-chip”, Lab on a Chip, 2007, pp. 423-440, vol. 7 No. 4.
- Svahn et al., “Single cells or large populations?”, Lab on a Chip, 2007, 544-546, vol. 7, No. 5.
- Tourovskaia et al., “Differentiation-on-a-chip: A microfluidic platform for long-term cell culture studies”, Lab on a Chip, 2005, pp. 14-19, vol. 5, No. 1.
- Unger et al., “Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography”, Science, 2000, pp. 113-116, vol. 288, No. 5463.
- Voleti et al., “Tendon healing: repair and regeneration”, Annual Review of Biomedical Engineering, 2012, pp. 47-71, vol. 14.
- Wall et al., “Comparison of cellular strain with applied substrate strain in vitro”, Journal of Biomechanics, 2007, pp. 173-181, vol. 40, No. 1.
- Wheeler et al., “Microfluidic Device for Single-Cell Analysis”, Analytical Chemistry, 2003, pp. 3581-3586, vol. 75, No. 14.
- Whitesides et al., “Soft Lithography in Biology and Biochemistry”, Annual Review of Biomedical Engineering, 2001, pp. 335-373, vol. 3.
- Yang et al., “Hydrodynamic simulation of cell docking in microfluidic channels with different dam structures”, Lab on a Chip, 2004, pp. 53-59, vol. 4, No. 1.
- Yang et al., “Cell Docking and On-Chip Monitoring of Cellular Reactions with a Controlled Concentration Gradient on a Microfluidic Device”, Analytical Chemistry, 2002, pp. 3991-4001, vol. 74, No. 16.
Type: Grant
Filed: Mar 11, 2020
Date of Patent: May 4, 2021
Assignee: MedTrain Technologies, LLC (Burlington, NC)
Inventors: Albert J. Banes (Hillsborough, NC), Colin Patrick Frazier (Raleigh, NC), Christopher James Wimmer (Raleigh, NC)
Primary Examiner: Vy N Koenig
Application Number: 29/727,514