Patents Issued in April 1, 2004
  • Publication number: 20040064840
    Abstract: A broadcasting method using a PDA as a signal relay device has the steps of (a) modulating a sound file intended to be broadcast, wherein the sound file stored in a PDA is modulated in the form of a radio wave at a set frequency, (b) transmitting the modulated radio wave, (c) demodulating and (d) playing the radio wave to obtain the sound file by any radio device. A broadcasting apparatus utilizes a modulating module that is integrated into a charging base of the PDA to modulate sound files stored in the PDA. the modulated sound files can be transmitted in the form of a radio wave and then be demodulated and played by any radio receiving device.
    Type: Application
    Filed: September 30, 2002
    Publication date: April 1, 2004
    Inventor: Huo-Pei Liu
  • Publication number: 20040064841
    Abstract: The present invention relates to animals that express exogenous growth factors in their milk, and in particular to pigs that express exogenous IGF-I in their milk. The present invention also relates to methods for increasing piglet weight gain and intestinal lactase activity. The present invention thus provides a method of facilitating piglet development and decreasing piglet mortality.
    Type: Application
    Filed: September 30, 2003
    Publication date: April 1, 2004
    Applicant: Board of Trustees of the University of Illinois
    Inventors: Matthew B. Wheeler, Sharon M. Donovan, Gregory T. Bleck, Marcia Monaco-Seigel
  • Publication number: 20040064842
    Abstract: The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilises recombinant DNA technology to post-transcriptionally modify or modulate the expression of a target gene in a cell tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided.
    Type: Application
    Filed: August 22, 2003
    Publication date: April 1, 2004
    Inventors: Michael Wayne Graham, Robert Norman Rice
  • Publication number: 20040064843
    Abstract: A method is disclosed for improving the reliability of physical measurements obtained from array hybridization studies performed on an array having a large number of genomic samples including a replicate subset containing a small number of replicates insufficient for making precise and valid statistical inferences. An error in measurement of a sample is estimated by combining estimates obtained with individual samples in the replicate subset, and utilizing the estimated sample error as a standard for accepting or rejecting the measurement of a sample under test.
    Type: Application
    Filed: July 24, 2003
    Publication date: April 1, 2004
    Inventors: Edward Susko, Robert Nadon
  • Publication number: 20040064844
    Abstract: The present invention relates to in vitro and in vivo assays for the identification of agents that are useful in the treatment of neurodegenerative diseases that are associated with defects in protein folding. The present further relates to in vitro and in vivo assays for the identification of agents that contribute to the neurodegenerative processes which occur in these diseases. The present invention also relates to in vitro and in vivo models of neurodegenerative diseases. These assays and models will be useful in further understanding the pathogenesis of various neurodegenerative diseases in which defects in protein folding have been implicated, in identifying additional endogenous or environmental factors that contribute to the etiologies of these diseases, and in developing effective therapies for the prevention and/or treatment of these diseases.
    Type: Application
    Filed: September 26, 2002
    Publication date: April 1, 2004
    Inventors: Thomas C. Sudhof, Bernd Stahl, Soenke Tobaben
  • Publication number: 20040064845
    Abstract: The present invention relates to cloning method of animals. The invention includes cell lines, reconstructed embryos and cloned or transgenic animals. In particular, the invention provides method of cloning animals by combining genome of donor cells at specific stages of the cell cycle without uses of chemical products, with activated enucleated oocyte to thereby obtain reconstructed embryos. The invention further relates to methods of culturing animal cells until confluence in normal conditions avoiding negative genetic mutations induced by chemicals. Also, the invention relates to a method of preparing recipient oocytes before nuclear transfer, and to a culture medium improving the in vitro as well as in vivo development of reconstructed embryos.
    Type: Application
    Filed: October 22, 2003
    Publication date: April 1, 2004
    Inventors: Lawrence Charles Smith, Vilceu Bordignon, Jose Henrique Fortes Pontes
  • Publication number: 20040064846
    Abstract: This invention provides a method of conferring osmoprotection to plants. Plant plastid genomes, particularly the chloroplast genome, is transformed to express an osmoprotectant. The transgenic plants and their progeny display drought resistance. More importantly, such transgenic plants display no negative pleiotropic effects such as sterility or stunted growth.
    Type: Application
    Filed: February 11, 2002
    Publication date: April 1, 2004
    Inventors: Henry Daniell, Seung-Bum Lee, Myung Ok Byun
  • Publication number: 20040064847
    Abstract: Transgenic plants that express antimicrobial CEMA and/or CEMA-related peptides are disclosed. In certain embodiments, these plants have enhanced, broad-spectrum pathogen resistance and are useful as agricultural or horticultural crops. In other embodiments, the plants are used to produce large quantities of the CEMA and/or CEMA-related peptides.
    Type: Application
    Filed: April 21, 2003
    Publication date: April 1, 2004
    Applicant: University of Victoria Innovation and Development Corporation
    Inventors: Santosh Misra, William W. Kay, Milan Osusky
  • Publication number: 20040064848
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a chorismate biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the chorismate biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the chorismate biosynthetic enzyme in a transformed host cell.
    Type: Application
    Filed: September 11, 2003
    Publication date: April 1, 2004
    Inventors: Rebecca E. Cahoon, Saverio Carl Falco, Layo O. Famodu, William D. Hitz, Alan R. Rendina
  • Publication number: 20040064849
    Abstract: The invention relates to the field of secondary metabolite production in plants and plant cell cultures. More specifically, the invention relates to the use of transporters and more particularly ABC-transporters to enhance the production and/or secretion of secondary metabolites in plants and plant cell cultures.
    Type: Application
    Filed: September 18, 2003
    Publication date: April 1, 2004
    Applicant: Vlaams Interuniversitair Instituut Voor Biotechnologie VZW
    Inventors: Alain Goossens, Dirk Gustaaf Inze
  • Publication number: 20040064850
    Abstract: An antifungal polypeptide, AlyAFP, that controls fungal damage to plants is provided. DNA encoding this polypeptide can be cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptide can be formulated into compositions that can be used to control undesired fingi on plants and elsewhere.
    Type: Application
    Filed: October 9, 2003
    Publication date: April 1, 2004
    Inventors: Jihong Liang, Dilip Maganlal Shah, Yonnie Shun Wu, Cindy Annette Rosenberger
  • Publication number: 20040064851
    Abstract: The present invention concerns a transgenic plant which can produce isomaltulose, a transgenic plant which can produce 6-O-&agr;-D-glucopyranosyl-D-sorbitol, a transgenic plant which can produce 1-O-&agr;-D-glucopyranosyl-D-mannitol, a transgenic plant which can produce a mixture of 1,6-GPs and 1,1-GPM, propagation and harvest material from these plants, and a process for producing these transgenic plants.
    Type: Application
    Filed: August 18, 2003
    Publication date: April 1, 2004
    Inventors: Markwart Kunz, Ralf Mattes, Mohammed Munir, Manfred Vogel
  • Publication number: 20040064852
    Abstract: The present invention is in the field of fructan producing plants. Furthermore the present invention is directed to the production of at least 3 degree of polymermization. Additionally, the present invention is more specifically directed to non fructan producing plant which are transformed or crossed to contain at least two genes of the three fructosyltransferase.
    Type: Application
    Filed: September 22, 2003
    Publication date: April 1, 2004
    Inventors: Guy Weyens, Jean Lathouwers, Cornelius (Kees) Van Dun
  • Publication number: 20040064853
    Abstract: The invention relates to tissue specific promoters which can be used in plants for one or more of the following purposes: a. altering carbohydrate metabolism b. preventing memory substance loss c. expression of an invertase inhibitor d. expression of a fructosyl transferase e. expression of a levan sucrase f. expression of genes coding for transported proteins for N-compounds g. expression of characteristics which increase resistance/tolerance with respect to pathogens.
    Type: Application
    Filed: September 15, 2003
    Publication date: April 1, 2004
    Inventors: Reinhard Hehl, Dorothee Kloos, Dietmar Jurgen Stahl
  • Publication number: 20040064854
    Abstract: Plant promoters that exhibit seed-associated expression are described, including bi-directional promoters capable of directing seed-associated expression in either orientation.
    Type: Application
    Filed: August 1, 2003
    Publication date: April 1, 2004
    Inventors: Stephanie K. Clendennen, Jonathan Lightner, Debra K. Schuster
  • Publication number: 20040064855
    Abstract: The invention relates to the production of enzymatically active recombinant human and animal lysosomal enzymes involving construction and expression of recombinant expression constructs comprising coding sequences of human or animal lysosomal enzymes in a plant expression system. The plant expression system provides for post-translational modification and processing to produce a recombinant gene product exhibiting enzymatic activity. The invention is demonstrated by working examples in which transgenic tobacco plants express recombinant expression constructs comprising human glucocerebrosidase nucleotide sequences. The invention is also demonstrated by working examples in which transfected tobacco plants express recombinant viral expression constructs comprising human &agr; galactosidase nucleotide sequences.
    Type: Application
    Filed: October 9, 2003
    Publication date: April 1, 2004
    Applicant: LARGE SCALE BIOLOGY CORPORATION
    Inventors: Gregory P. Pogue, Thomas H. Turpen, Monto H. Kumagai, Robert L. Erwin, Laurence K. Grill
  • Publication number: 20040064856
    Abstract: The invention provides compositions and methods for regulating expression of heterologous nucleotide sequences in a plant. Compositions are nucleotide sequences for tissue-independent or constitutive promoters for genes encoding actin-2, enolase, Gos-2 and L41. A method for expressing a heterologous nucleotide sequence in a plant using the promoter sequences disclosed herein is provided. The method comprises transforming a plant cell with a nucleotide sequence operably linked to one of the promoters of the present invention and regenerating a stably transformed plant from the transformed plant cell.
    Type: Application
    Filed: October 21, 2003
    Publication date: April 1, 2004
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Eric Barbour, Terry EuClaire Meyer, Mohamed Eid Saad
  • Publication number: 20040064857
    Abstract: The present invention is directed to the production of male sterile plants by providing them with a recombinant DNA capable of specific expression in the male reproductive system of a plant of the enzyme trehalose phosphate phosphatase (TPP). Restoration of the fertility can be established either by providing said male sterile plants with a recombinant DNA capable of expression of trehalose phosphate synthase (TPS) under control of an inducible promoter or with a recombinant DNA capable of expression of a suppressor protein which suppresses expression of TPP under control of an inducible promoter. This inducible restoration possibilities enable the maintenance site-specific recombination system is provided, by inserting two site-specific recombination sites flanking the recombinant DNA coding for TPP and crossing the male sterile lines with lines expressing the corresponding recombinase. By crossing the recombinase will excise the gene coding for TPP and fertile hybrids are produced.
    Type: Application
    Filed: May 28, 2003
    Publication date: April 1, 2004
    Inventors: Cornelis Maria Petrus Van Dun, Oscar Johannes Maria Goddijn
  • Publication number: 20040064858
    Abstract: This invention concerns the construction of transgenic soybean lines wherein the expression of genes encoding seed storage proteins are modulated to effect a change in seed storage protein profile of transgenic plants. Modification of the seed storage protein profile can result in the production of novel soy protein products with unique and valuable functional characteristics.
    Type: Application
    Filed: October 14, 2003
    Publication date: April 1, 2004
    Inventors: Anthony John Kinney, Gary Michael Fader
  • Publication number: 20040064859
    Abstract: A novel soybean cultivar, designated 926877, is disclosed. The invention relates to the seeds of soybean cultivar 926877, to the plants of soybean 926877 and to methods for producing a soybean plant produced by crossing the cultivar 926877 with itself or another soybean variety. The invention further relates to hybrid soybean seeds and plants produced by crossing the cultivar 926877 with another soybean cultivar.
    Type: Application
    Filed: September 27, 2002
    Publication date: April 1, 2004
    Applicants: Stine Seed Farm, Inc., Asgrow Seed Company LLC
    Inventors: William H. Eby, Beth A. Holmes
  • Publication number: 20040064860
    Abstract: An inbred corn line, designated N16028, is disclosed. The invention relates to the seeds of inbred corn line N16028, to the plants of inbred corn line N16028 and to methods for producing a corn plant, either inbred or hybrid, by crossing the inbred line N16028 with itself or another corn line. The invention further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred corn lines derived from the inbred N16028.
    Type: Application
    Filed: September 27, 2002
    Publication date: April 1, 2004
    Inventor: Duane Wolf
  • Publication number: 20040064861
    Abstract: An inbred corn line, designated N10018, is disclosed. The invention relates to the seeds of inbred corn line N10018, to the plants of inbred corn line N10018 and to methods for producing a corn plant, either inbred or hybrid, by crossing the inbred line N10018 with itself or another corn line. The invention further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred corn lines derived from the inbred N10018.
    Type: Application
    Filed: September 27, 2002
    Publication date: April 1, 2004
    Inventor: Duane Wolf
  • Publication number: 20040064862
    Abstract: An inbred corn line, designated E24018, is disclosed. The invention relates to the seeds of inbred corn line E24018, to the plants of inbred corn line E24018 and to methods for producing a corn plant, either inbred or hybrid, by crossing the inbred line E24018 with itself or another corn line. The invention further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred corn lines derived from the inbred E24018.
    Type: Application
    Filed: September 27, 2002
    Publication date: April 1, 2004
    Inventor: Duane Grensteiner
  • Publication number: 20040064863
    Abstract: The most distinctive feature of the rabbiteye blueberry, ‘Alapaha’, is its combination of early ripening and late flowering. This combination results in reduction of frost damage during flowering, with subsequent significant increases in productivity of high quality fruit over the current early varieties for Georgia.
    Type: Application
    Filed: September 26, 2002
    Publication date: April 1, 2004
    Inventors: D. Scott NeSmith, Arlen D. Draper
  • Publication number: 20040064864
    Abstract: Hydrangea macrophylla ‘Lady in Red’ is a lacecap with the sterile florets of the inflorescences maturing from pale pink to burgundy rose. It has lustrous reddish-purple leaf venation, petiole and stem color, and the foliage develops a red-purple fall color. The plant has high mildew resistance.
    Type: Application
    Filed: October 1, 2002
    Publication date: April 1, 2004
    Inventor: Michael A. Dirr