Patents Issued in December 7, 2004
  • Patent number: 6827906
    Abstract: A continuous form microstructure array device is constructed as a flexible elongate film laminate containing a plurality of microstructures or arrays of microstructures arranged serially lengthwise along the laminate. The laminate can be continuously drawn from a supply roll or stack, advanced within an analytic device and, when analysis is complete, taken up in a storage roll or stack. The device provides for high throughput microfluidic processing.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: December 7, 2004
    Assignee: Aclara Biosciences, Inc.
    Inventors: Torleif Ove Björnson, Laurence R. Shea
  • Patent number: 6827907
    Abstract: A compound handling system handles a multiplicity of chemical or biological compounds or samples, and is especially adapted for high throughput screening of compounds that are stored and handled in aliquotted form. Aliquots are contained in individual containers and the containers are arranged in racks having holding spaces open at opposite ends. Insertion and removal of the containers is effected in either direction of movement, and each container may be sealed with foil to protect its integrity.
    Type: Grant
    Filed: December 20, 2000
    Date of Patent: December 7, 2004
    Assignee: Hoffmann-LA Roche Inc.
    Inventors: Christof Fattinger, Hansjörg Tschirky
  • Patent number: 6827908
    Abstract: In a fluid catalytic cracking (FCC) unit, a regenerator, a stripper or a withdrawal well connecting to either of the vessels, includes a standpipe for circulating catalyst from one vessel to another, the standpipe having an inlet design which reduces gas entrainment during catalyst transport by partial de-fluidization in the standpipe inlet region. The standpipe inlet design could include multiple inlet openings through the top of the standpipe or from the side wall by slots, or both, and a horizontal disk surrounding the standpipe below the slots for blocking the upward flow of bubbles, the combination thereby forming a dense fluidization zone above the disk and surrounding the inlet, including the slots. Additionally, the disk may include a downwardly-projecting lip or edge forming an inverted void space around the standpipe and the downwardly-projecting edge may further include vent holes around its circumference which allow bubbles trapped under the disk to be vented outside the standpipe inlet region.
    Type: Grant
    Filed: July 12, 2000
    Date of Patent: December 7, 2004
    Assignee: Shell Oil Company
    Inventor: Ye-Mon Chen
  • Patent number: 6827909
    Abstract: A catalytic converter for cleaning exhaust gas from an internal combustion engine, in particular a diesel engine or a lean-burn engine, includes at least one honeycomb body coated with catalytically active material and having passages through which the exhaust gas can flow, walls separating the passages from each other, and first and second zones disposed in succession in a flow direction. The first zone has a lower thermal capacity per unit of volume of the honeycomb body than the second zone and the second zone has a thermal capacity of at least 800 joules per liter and Kelvin [J/lK], preferably at least 900. Sheet metal layers in the first zone preferably have an average uncoated thickness of less than 0.06 mm, preferably less than 0.04 mm. Sheet metal layers in the second zone preferably have an average uncoated thickness of more than 0.06 mm, preferably more than 0.08 mm and in particular 0.11 mm.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: December 7, 2004
    Assignee: Emitec Gesellschaft fuer Emissionstechnologie mbH
    Inventors: Rolf Brück, Jörg-Roman Konieczny
  • Patent number: 6827910
    Abstract: An electric ozone toothbrush mainly has a guide tube installed in an interior portion of a handle and a brush head of a regular electric toothbrush connecting with a bristle end of the brush head; the other end of the guide tube joins with a coil tube of an ozone generator; an air pump disposed inside the ozone generator guides the ozone into the bristle end of the brush head such that the released ozone sterilizes, deodorizes, whitens the teeth, disinfects and detoxifies during the brushing application of the electric toothbrush.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: December 7, 2004
    Inventor: Ching-Fu Chen
  • Patent number: 6827911
    Abstract: A system for the continuous use and recapture of a catalyst in liquid, comprising: a generally vertical reactor having a reaction zone with generally downwardly flowing liquid, and a catalyst recovery chamber adjacent the reaction zone containing a catalyst consisting of buoyant particles. The liquid in the reaction zone flows downward at a rate which exceeds the speed of upward buoyant migration of catalyst particles in the liquid, whereby catalyst particles introduced into the liquid in the reaction zone are drawn downward with the liquid. A slow flow velocity flotation chamber disposed below the reaction zone is configured to recapture the catalyst particles and allow them to float back into the catalyst recovery chamber for recycling into the reaction zone, rather than being swept downstream. A novel 3-dimensionally adjustable solar reflector directs light into the reaction zone to induce desired photocatalytic reactions within the liquid in the reaction zone.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: December 7, 2004
    Assignee: Bechtel BWXT Idaho, LLC
    Inventor: Kevin L. Gering
  • Patent number: 6827912
    Abstract: The invention relates to a reactor vessel and method for the gasification of carbon-containing fuel, residual and waste materials using an oxygen-containing oxidizing agent and in a reaction chamber which is designed as an entrained-bed reactor, at pressures between ambient pressure and 80 bar, preferably between ambient pressure and 30 bar, the contour of the reaction chamber being delimited by a cooling system, and the pressure in the cooling system always being held at a higher level than the pressure in the reaction chamber, and the cooling system withstanding the maximum possible pressure difference with respect to the reaction chamber, which has been depressurized to atmospheric pressure, which reactor vessel is distinguished by the fact that cooling channels are formed by webs which are in contact both with a refractory protective layer and with the pressure shell.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: December 7, 2004
    Assignee: Noell-KRC Energie-und Umwelttechnik GmbH
    Inventors: Manfred Schingnitz, Christian Reuther, Dietmar Degenkolb
  • Patent number: 6827913
    Abstract: A sterilization tray system which comprises an outer box-like case having holes in the case bottom wall through which steam or other sterilant may circulate through the case. Pairs of brackets are affixed vertically to opposite the case side and/or end walls. A plurality of spaced holes is provided in each bracket. The holes serve as anchoring points for shelf brackets or fixtures for supporting trays at selected positions in the case.
    Type: Grant
    Filed: February 1, 2002
    Date of Patent: December 7, 2004
    Assignee: Symmetry Medical, Inc.
    Inventor: Timothy E. Wood
  • Patent number: 6827914
    Abstract: A chemical process for the purification of CaSO4 utilizes the ability of an aqueous solution of a chelating agent to selectively dissolve CaSO4 in that the initial extraction can be carried out at certain pH and CaSO4 can be recovered by titration to a different pH (usually a a lower pH) following a mechanical treatment, such as centrifugation or filtration, to separate the aqueous chelate solution from insoluble material. Also claimed are an apparatus and the use of chelating agents therefor.
    Type: Grant
    Filed: October 29, 2001
    Date of Patent: December 7, 2004
    Inventor: Christopher Oldfield
  • Patent number: 6827915
    Abstract: Rare earth metal containing compounds of the general formula Sr2RESbO6, wherein RE is a rare earth metal, have been prepared with high critical temperature thin film superconductor strucutures, and can be used in other ferroelectrics, pyroelectrics, piezoelectrics, and hybrid device structures.
    Type: Grant
    Filed: April 26, 2001
    Date of Patent: December 7, 2004
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Arthur Tauber, Robert D. Finnegan, William D. Wilber, Steven C. Tidrow, Donald W. Eckart, William C. Drach
  • Patent number: 6827916
    Abstract: A preparation method of silica, especially superfine silica, with water glass and carbon dioxide as major raw materials in a carbonization reaction conducted under a high gravity field, typically in a Higee reactor.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: December 7, 2004
    Assignee: Beijing University of Chemical Technology
    Inventors: Kai Guo, Jianfeng Chen, Fen Guo, Hong Jia
  • Patent number: 6827917
    Abstract: A catalyst for oxidation reactions, particularly the oxidation of ammonia comprises oxides of (a) at least one element A selected from rare earths and yttrium, and (b) cobalt and element A being in such proportions that the element A to cobalt atomic ratio is in the range 0.8 to 1.2, at least some of said cobalt and element A oxides being present as a mixed oxide phase with less than 25% of the cobalt (by atoms) being present as free cobalt oxides, is disclosed. The catalyst may be supported on a secondary support in the form of an alkali-free alumina or lanthana wash coat on a primary support in the form of a mesh, gauze, pad, or monolith formed from a high temperature iron/aluminum alloy or a mesh, gauze, pad, monolith, or foam of a ceramic material.
    Type: Grant
    Filed: June 17, 1999
    Date of Patent: December 7, 2004
    Assignee: Johnson Matthey PLC
    Inventors: Andrew Mark Ward, Brett Albert Wolfindale, Frank King, Bernard John Crewdson
  • Patent number: 6827918
    Abstract: This invention is directed to making chemical derivatives of carbon nanotubes and to uses for the derivatized nanotubes, including making arrays as a basis for synthesis of carbon fibers. In one embodiment, this invention also provides a method for preparing single wall carbon nanotubes having substituents attached to the side wall of the nanotube by reacting single wall carbon nanotubes with fluorine gas and recovering fluorine derivatized carbon nanotubes, then reacting fluorine derivatized carbon nanotubes with a nucleophile. Some of the fluorine substituents are replaced by nucleophilic substitution. If desired, the remaining fluorine can be completely or partially eliminated to produce single wall carbon nanotubes having substituents attached to the side wall of the nanotube. The substituents will, of course, be dependent on the nucleophile, and preferred nucleophiles include alkyl lithium species such as methyl lithium.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: December 7, 2004
    Assignee: William Marsh Rice University
    Inventors: John L. Margrave, Edward T. Mickelson, Robert Hauge, Peter Boul, Chad Huffman, Jie Liu, Richard E. Smalley, Ken Smith, Daniel T. Colbert
  • Patent number: 6827919
    Abstract: A process for producing hollow, single-walled carbon nanotubes by catalytic decomposition of one or more gaseous carbon compounds by first forming a gas phase mixture carbon feed stock gas comprising one or more gaseous carbon compounds, each having one to six carbon atoms and only H, O, N, S or Cl as hetero atoms, optionally admixed with hydrogen, and a gas phase metal containing compound which is unstable under reaction conditions for said decomposition, and which forms a metal containing catalyst which acts as a decomposition catalyst under reaction conditions; and then conducting said decomposition reaction under decomposition reaction conditions, thereby producing said nanotubes.
    Type: Grant
    Filed: June 29, 2000
    Date of Patent: December 7, 2004
    Assignee: Hyperion Catalysis International, Inc.
    Inventors: David Moy, Asif Chishti
  • Patent number: 6827920
    Abstract: A method for preparing barium fluorohalide-based crystal, which includes at least a step in which a halide aqueous solution (B) and aqueous solutions of a fluoride and a barium salt are mixed into a halide aqueous solution (A). The halide aqueous solution (B) contains the same halogen as that contained in the halide aqueous solution (A). In this method, halide ions are used efficiently rather than remaining to form a waste residue.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: December 7, 2004
    Assignee: Fuji Photo Film Co., Ltd.
    Inventor: Masaharu Nakatsu
  • Patent number: 6827921
    Abstract: Ultrafine powders of Li4Ti5O12 with particles in the size range of 25-500 nm. The average size of particles is about 500 nm of less, preferably about 300 nm or less. The particles are composed of nanocrystallites, which have an average size about 30 nm. This invention also includes the method of producing these ultrafine Li4Ti5O12 particles. The process utilizes (i) nanoparticles of TiO2, (ii) a lithium salt, and (iii) an organic solvent with a boiling point in the range of 70-230° C. The process is carried out at pressures in the range of 0.5 to 10 atmospheres. The inorganic salt of Li is mixed with TiO2 nanoparticles (˜20-25 nm) in the organic solvent. The solution is heated to a temperature and at a pressure to facilitate the diffusion of Li ions in to nanoparticles. After completion of the reaction, the powder is heat treated in O2 or an inert gas to form the desired phase.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: December 7, 2004
    Assignee: Nanopowder Enterprises Inc.
    Inventors: Amit Singhal, Ganesh Skandan
  • Patent number: 6827922
    Abstract: A process for producing a titanium oxide is provided which comprises (i) a step of calcining a titanium compound in the presence of ammonia gas or (ii) steps of treating a titanium compound with heat in the presence of ammonia gas and calcining the heat-treated titanium compound. The titanium oxide obtained in the present invention exhibits a sufficiently high photocatalytic activity by irradiation of visible light.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: December 7, 2004
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Yoshinari Sawabe, Yoshiaki Sakatani, Hironobu Koike
  • Patent number: 6827923
    Abstract: Aluminium hydroxide of high whiteness is produced by (i) heating aluminium hydroxide obtained from the Bayer process to a temperature of 300 to 700° C. (ii) dissolving the soluble fraction of the thus obtained activated product at 85 to 275° C. in aqueous sodium hydroxide to form a sodium aluminate liquor containing an undissolved residue of very fine boehmite, (iii) filtering said sodium aluminate liquor to obtain a clear solution of sodium aluminate supersaturated with respect to dissolved alumina, (iv) cooling said clear solution to 50 to 80° C. and seeding with crystallized aluminium hydroxide to induce further crystallization, and (v) separating, washing and drying the produced aluminium hydroxide crystals.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: December 7, 2004
    Assignee: Albemarle Corporation
    Inventor: Neil Brown
  • Patent number: 6827924
    Abstract: The present invention relates to the preparation of nanocrystalline zeolite beta by a modified aerogel protocol comprising four steps, namely, hydrolysis, nucleation, crystallization and supercritcal drying.
    Type: Grant
    Filed: November 29, 2002
    Date of Patent: December 7, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Kottapalli Koteswara Rao, Bhavnari Puma Chandra Rao, Boyapati Manoranjan Choudary, Lakshmi Kantam Mannepalli, Vijaya Raghavan Kondapuram
  • Patent number: 6827925
    Abstract: Specific binding members, based on the third CDR of the antibody NHS76 (SEQ ID NO: 2) are provided, together with their use in methods of treatment and diagnosis.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: December 7, 2004
    Assignee: Cambridge Antibody Technology Limited
    Inventors: Andrew James Williams, Philip Ronald Tempest, Thor Las Holtet, Helen Jackson
  • Patent number: 6827926
    Abstract: Metallotetrapyrrolic compounds having photherapeutic properties useful in photodetection and phototherapy of target issues, particularly porphyrins and azaporphyrins that including gallium in the central pyrrolic core. Also disclosed are methods of using metallotetrapyrrolic compounds for the treatment or detection of cardiovascular disease.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: December 7, 2004
    Assignee: Miravant Pharmaceuticals, Inc.
    Inventors: Byron C. Robinson, Ian M. Leitch, Stephanie Greene, Steve Rychnovsky
  • Patent number: 6827927
    Abstract: The invention concerns a racemic compound of the pair of enantiomers of formula (III) wherein R represents an alkyl group or a phenyl group optionally substituted.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: December 7, 2004
    Assignee: Guerbet
    Inventors: Olivier Rousseaux, Christian Simonot
  • Patent number: 6827928
    Abstract: The subject-matter of the present invention is a transfer-free composition comprising (a) at least one of a di-block, tri-block, multi-block and/or radial block copolymer and optionally (b) a film former or a mixture of film formers. The composition may comprise any one of a di-block, tri-block, multi-block or radial block copolymer or any mixture or blend of co-polymers. Cosmetic and pharmaceutical compositions of the invention result in a film with very good retention, good transfer resistant properties, and which does not migrate over time. The compositions have cosmetic properties which are improved in relation to those of the “transfer free” products of the prior art.
    Type: Grant
    Filed: January 23, 2002
    Date of Patent: December 7, 2004
    Assignee: L'Oreal S.A.
    Inventors: Carolyn Caes, Gary G. Graves, Mohamed G. Kanji, Margarita Montes De Oca, Greg Norman, Carl Orr, Paul Thau
  • Patent number: 6827929
    Abstract: A composition comprising 1-25 wt. % of a silicone gum, 1-40 wt. % of a silicone fluid having a viscosity of 10 to 60,000 mm2/sec, 1-35 wt. % of a silicone wax and 20-90 wt. % of a volatile silicone fluid having a viscosity up to and including 5 mm2/s at 25° C. can be used for the treatment of scars resulting from injury or surgery.
    Type: Grant
    Filed: July 2, 2002
    Date of Patent: December 7, 2004
    Assignee: Dow Corning France S.A.
    Inventors: Gary Lord, Marie Therese Valencia, Xavier Thomas
  • Patent number: 6827930
    Abstract: A sport fishing system having: a rod and reel, including fishing line; at least one fishing lure or natural bait; and a controlled released fish attractant for applying to the fishing lure or natural bait. The system may further include an applicator for applying the controlled released fish attractant to the fishing lure or natural bait. In the preferred embodiment, the controlled release fish attractant includes: an attractant and a substantially hydrophobic, film forming release agent.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: December 7, 2004
    Assignee: Carolina Lunker Sauce, L.L.C.
    Inventors: Stephen Russell Cobb, Michael D. Jacobson, Joseph A. Lupia
  • Patent number: 6827931
    Abstract: Methods for treating endocrine disorders and for inhibiting gametogenesis by intracranial administration to a human patient of a therapeutically effective amount of a neurotoxin, such as a botulinum toxin type A.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: December 7, 2004
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Patent number: 6827932
    Abstract: The invention provides a composition which is effective in the prevention or delay of the onset of side effects associated with alcohol consumption or the reduction or alleviation of those effects. The composition of the invention includes activated charcoal and limestone, optionally activated limestone. Optionally, the composition of the invention also includes vitamin B1 and/or other agents such as fatigue relieving agents. Preferably, the composition of the invention is provided in the form of tablets or powder encapsulated in a gelatin capsule. The composition of the invention is provided in pre-dosed quantities varying from between about 100 and 500 milligrams per dose. The invention also provides a method of reducing or alleviating the deleterious effects associated with alcohol consumption.
    Type: Grant
    Filed: January 11, 2002
    Date of Patent: December 7, 2004
    Inventors: Raymond Crippen, Manoj Bhargava, Thomas F. Morse
  • Patent number: 6827933
    Abstract: A purified human papillomavirus gene selected from the group consisting of E1, E6-E7, L1, and L2, wherein said human papillomavirus is selected from the group consisting of HPV-2d, HPV-10b, HPV-14a, HPV-14b, HPV-15, HPV-17a, HPV-17b, HPV-19, HPV-20, HPV-21, HPV-22, HPV-23, HPV-24, HPV-28, HPV-29, HPV-31, HPV-32, HPV-IP2 and HPV-IP4. Polypeptides encoded by these genes. The polypeptides can be used in immunogenic compositions.
    Type: Grant
    Filed: November 15, 2001
    Date of Patent: December 7, 2004
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Gerard Orth, Sylvie Beaudenon, Michel Favre, Dina Kremsdorf, Odile Croissant, Gerard Pehau-Arnaudet
  • Patent number: 6827934
    Abstract: The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: December 7, 2004
    Assignee: Genetics Institute, LLC
    Inventors: Man Sung Co, Maximiliano Vasquez, Beatriz Carreno, Abbie Cheryl Celniker, Mary Collins, Samuel Goldman, Andrea Knight, Denise O'Hara, Bonita Rup, Geertruida M. Veldman, Gary S. Gray
  • Patent number: 6827935
    Abstract: A method of inhibiting, moderating or diagnosing Pseudomonas aeruginosa infection is disclosed. In one embodiment, this method comprises inoculating a patient with an effective amount of PcrV antigen.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: December 7, 2004
    Assignees: MCW Research Foundation, Regents of the University of California
    Inventors: Dara W. Frank, Jeannine Wiener-Kronish, Timothy L. Yahr, Teiji Sawa, Robert B. Fritz
  • Patent number: 6827936
    Abstract: Vaccine compositions and immunogenic compositions are described which are glucosyltransferase subunit vaccines for dental caries and which contain at least one peptide which corresponds to a sequence of glucosyltransferase containing aspartate 413, an equivalent of aspartate 413, aspartate 451, an equivalent of aspartate 451, aspartate 562, and equivalent of aspartate 562, aspartate 567, an equivalent of aspartate 567, histidine 561, an equivalent of histidine 561, tryptophan 491, an equivalent of tryptophan 491, glutamate 489, an equivalent of glutamate 489, arginine 449, an equivalent of arginine 449, or combinations thereof. These subunit vaccines elicit antibodies which protect an immunized mammal from dental caries. Methods of provoking an immune response to intact glucosyltransferase are also described.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: December 7, 2004
    Assignee: Forsyth Dental Infirmary for Children
    Inventors: Daniel J. Smith, Martin A. Taubman
  • Patent number: 6827937
    Abstract: This invention relates to hepatitis B virus (“HBV”) core antigen particles that are characterized by multiple immunogen specificities. More particularly, the invention relates to HBV core antigen particles comprising immunogens, epitopes, or other related structures, crosslinked thereto by ligands which are HBV capsid-binding peptides that selectively bind to HBV core protein. Such particles may be used as delivery systems for a diverse range of immunogenic epitopes, including the HBV capsid-binding peptides, which advantageously also inhibit and interfere with HBV viral assembly by blocking the interaction between HBV core protein and HBV surface proteins. Mixtures of different immunogens and/or capsid-binding peptide ligands may be crosslinked to the same HBV core particle. Such resulting multicomponent or multivalent HBV core particles may be advantageously used in therapeutic and prophylactic vaccines and compositions, as well as in diagnostic compositions and methods using them.
    Type: Grant
    Filed: May 29, 2003
    Date of Patent: December 7, 2004
    Assignee: Biogen Idec MA Inc.
    Inventor: Kenneth Murray
  • Patent number: 6827938
    Abstract: Materials and methods for improving kidney function or enhancing proliferation or survival of kidney tubule epithelial cells or epithelial cell precursors in a mammal are disclosed. The methods comprise administering to the mammal a composition comprising a therapeutically effective amount of a zvegf4 protein or a zvegf4 protein-encoding polynucleotide in combination with a pharmaceutically acceptable delivery vehicle. Zvegf4 proteins include, for example, disulfide-bonded dimers of two polypeptide chains, each comprising residues 258-370 of SEQ ID NO:2.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: December 7, 2004
    Assignee: ZymoGenetics, Inc.
    Inventors: Charles E. Hart, Stavros Topouzis
  • Patent number: 6827939
    Abstract: The peptide in this invention is a peptide having affinity to gp120 represented by H-A1-A2-A3-A4-A5-R (SEQ ID No. 1)  Formula (1) (in the formula, H means hydrogen, A1 is aspartic acid, lysine, valine, glutamic acid, glycine, asparagine, or tyrosine residue, A2 is valine, aspartic acid, tryptophan, lysine, phenylalanine, isoleucine, leucine, or tyrosine residue, A3 is lysine, valine, aspartic acid, arginine, alanine, or tryptophan residue, A4 is alanine, tryptophan, or glycine residue, A5 is glycine, alanine, valine, leucine, isoleucine, serine, threonine, methionine, asparagine, glutamine, histidine, lysine, arginine, phenylalanine, tryptophan, proline, or tyrosine residue, R is OH derived from carboxyl group or NH2 derived from acid amide group).
    Type: Grant
    Filed: January 11, 2001
    Date of Patent: December 7, 2004
    Assignee: MedRx Co., Ltd.
    Inventors: Takeru Fujii, Hideakira Yokoyama, Hidetoshi Hamamoto
  • Patent number: 6827940
    Abstract: A method of obtaining a pharmacologically active extract of the cell walls of Gram-positive bacteria is disclosed. The method involves the treatment of the bacteria with acid such that the immune-stimulating properties are enhanced. The extracts have immune stimulating and anti-tumor activities with no toxicity at effective doses. The final products are stable, water-soluble powders.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: December 7, 2004
    Assignee: Aidan Products, LLC
    Inventors: Neil H. Riordan, XiaoLong Meng, Hugh D. Riordan
  • Patent number: 6827941
    Abstract: Carotenoid aggregates are useful as colorants for foods and for cosmetic and pharmaceutical preparations.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: December 7, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Erik Lüddecke, Helmut Auweter, Loni Schweikert
  • Patent number: 6827942
    Abstract: A liquid composition comprising an alcohol or mixture thereof in sufficient quantity to grow hair in an area of canine or feline skin wherein alopecia has occurred.
    Type: Grant
    Filed: December 4, 2000
    Date of Patent: December 7, 2004
    Assignee: Colgate-Palmolive Co.
    Inventors: Shiguang Yu, Karen Wedekind
  • Patent number: 6827943
    Abstract: Described are dermatological compositions for treating, protecting and re-epitheliazing cutaneous wounds and damaged skin, such compositions including about 21 to about 40% urea and trace amounts of zinc, copper and manganese in the form of their respective pharmaceutically acceptable salts.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: December 7, 2004
    Assignee: Bradley Pharmaceuticals, Inc.
    Inventors: Bradley P. Glassman, Dileep Bhagwat, Daniel Glassman
  • Patent number: 6827944
    Abstract: Provided is a composition for percutaneous administration containing a mixture of polymers forming a surface-segregated film, and (B) an active ingredient. The composition provides excellent percutaneous absorption efficacy of the active ingredient, particularly, a water-soluble active ingredient, has excellent feeling and is convenient to use.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: December 7, 2004
    Assignee: Kao Corporation
    Inventors: Masaru Hosokawa, Kumiko Shimizu, Toshio Uesaka, Ichiro Sugai, Shinobu Mori
  • Patent number: 6827945
    Abstract: A nutritional supplement for providing, and for promoting the health of salivary glands and/or supporting normal or healthy swallowing includes ingredients obtainable from turmeric, ginger, and horseradish. The nutritional supplement may also be used to treat symptoms such as symptoms of a common cold, sore throat, congestion, mucositis, laryngitis, mucous membrane inflammation and sialorrhea, as well as inflammation and viral infectin, or to inhibit or exterminate a virus. This nutritional supplement can be orally administered a person. The nutritional supplement may further include optional ingredients such as ingredients obtainable from slippery elm bark powder and green tea, as well as other optional ingredients. This nutritional supplement may further include a pharmaceutically acceptable carrier for oral administration.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: December 7, 2004
    Assignee: The Quigley Corporation
    Inventor: Richard A. Rosenbloom
  • Patent number: 6827946
    Abstract: Compositions comprising both a sedative and a non-sedative antihistamine are disclosed as well as methods of inhibiting the release of histamines by administration of the compositions to a mammalian subject.
    Type: Grant
    Filed: December 5, 2001
    Date of Patent: December 7, 2004
    Assignee: Collegium Pharmaceutical, Inc.
    Inventor: Mark Hirsh
  • Patent number: 6827947
    Abstract: A film coating composition suitable for use in coating pharmaceutical formulations to provide modified release comprising a dispersion which includes: a) an acrylic polymer, b) a vinyl acetate polymer, and c) a water-containing liquid. The film coat is useful for the achievement of modified release from pharmaceutical formulations such as tablets, pellets, etc.
    Type: Grant
    Filed: June 16, 2003
    Date of Patent: December 7, 2004
    Assignee: AstraZeneca AB
    Inventors: Jan-Erik Löfroth, Staffan Schantz, Anders Welin, Lars Johan Pontus de Verdier Hjartstam
  • Patent number: 6827948
    Abstract: The present invention provides a method and compositions for processing poultry feathers. In one embodiment, the method for processing poultry feathers comprises contacting a plurality of poultry feathers having an average particle size with a detergent capable of imparting a static charge to the plurality of poultry feathers; reducing the average particle size of the plurality of poultry feathers; increasing entanglement of the plurality of poultry feathers; adding an anionic polymeric adduct to the plurality of poultry feathers; adding a cationic species to the plurality of poultry feathers; and dewatering the plurality of poultry feathers. In another embodiment, a composition for processing poultry feathers, comprises a detergent capable removing at least a portion of fats and oils from a poultry feather and imparting a static charge to the poultry feather; an antimicrobial compound; an anionic polymeric adduct; and a cationic species.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: December 7, 2004
    Assignee: Steen Research LLC
    Inventor: Michael J. Stoltz
  • Patent number: 6827949
    Abstract: A wood preservative that comprises as an active ingredient a Piper methysticum, plant or a processed product thereof or a compound represented by Formula (I): wherein R1, R2, R3, R4 and R16 are same or different and each denotes a hydrogen atom, hydroxy or a C1-4 alkoxy, or R1 and R2 are taken together to form a group represented by —O—(CH2)n—O— wherein n is an integer of 1 to 3, R5 is a C1-4 alkoxy and X is —CH═CH—, —CH2—CH2— or epoxyethylene, and the bond: denotes a single bond or a double bond can prevent the attacking wood by an insect harmful to the wood and also prevents the appearance and the growth of a wood-rotting fungus or a wood- staining fungus while being highly safe to humans and animals without exerting no adverse effect on the environment.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: December 7, 2004
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Shinji Yoshida, Munekazu Iinuma
  • Patent number: 6827950
    Abstract: The present invention relates to Aralia extracts and a therapeutic agent comprising Aralia extracts as an active ingredient. The composition and therapeutic agent according to the present invention are effective in preventing cataract, delaying the development of cataract, and treating cataract. According to the present invention, extracts of Aralia are obtained by extraction with alcohol. Addition of myo-inositol or taurine to the extracts will result in a synergistic effect in the treatment of cataract. In addition, oral administration of beverages, galenicals, and nutraceuticals, which comprise Aralia extracts as an active ingredient, will be effective in prevention, delay and treatment of cataract caused by complications of diabetes. Aralia extracts will have the same effect in the case where they are used as an ophthalmic agent. They can also be used as an eye drop or an eye ointment.
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: December 7, 2004
    Assignee: Medvill Co., Ltd.
    Inventors: Eun-Kyung Hong, Young-Shin Chung, Yeong-Bok Han, Yun Hui Choi, Seong-Jin Kim, Hae-Ri Kim, Bu-Hyeon Kang
  • Patent number: 6827951
    Abstract: A method is provided for effecting smoke detoxification in a human by using a composition that is made of effective amounts of supercritical extract and hydroalcoholic extract of turmeric.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: December 7, 2004
    Assignee: New Chapter, Inc.
    Inventors: Thomas Newmark, Paul Schulick
  • Patent number: 6827952
    Abstract: Lactobacillus sanfranciscencis strains according to the present invention having a property for producing a non-organic acid antibacterial agent which exhibits at least mold-proofing activity. A fermented seasoning liquid of Lactobacillus according to the present invention may contain a Lactobacillus strain having a property for producing an antibacterial agent that inhibits the growth of mold. A method for producing bread according to the present invention may involve the use of a fermented seasoning liquid of a Lactobacillus strain having a property for producing an antibacterial agent which inhibits the growth of mold to make bread.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: December 7, 2004
    Assignee: Oriental Yeast Co., Ltd.
    Inventors: Masayasu Ando, Yoshiaki Shinomiya, Natsuko Nakamura
  • Patent number: 6827953
    Abstract: The present invention provides a composition comprising an untreated or treated culture of a mixed microorganism and a functional food comprising said composition. A composition comprising an untreated or treated culture of a mixed microorganism comprising at least three lactic acid bacteria selected from the group consisting of Lactobacillus delbrueckii, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus fermentum, Lactobacillus casei, Lactobacillus rhamnosus, Lactococcus lactis and Streptococcus thermophilus, mixed with Saccharomyces cerevisiae, and a functional food comprising said composition.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: December 7, 2004
    Assignees: Riken, A.L.A. Corporation
    Inventors: Takeo Mizutani, Ryouichi Shin, Momoyo Suzuki, Kazushi Miura
  • Patent number: 6827954
    Abstract: The present invention relates to tasty, ready-to-eat, nutritional foods that offer an alternative to appealing but unhealthy foods. More particularly, tasty, ready-to-eat, nutritional foods that provide a balanced mix of amino acids, fat, and carbohydrates are disclosed. Processes for making, and methods of using said tasty, ready-to-eat, nutritional foods are also disclosed. The nutritious foods of the present invention are formulated and processed such that they resolve the dilemma that consumers have always been faced with—healthy eating or enjoying what they eat.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: December 7, 2004
    Assignee: Mid-America Commercialization Corporation
    Inventors: Robert Lawrence Prosise, Christopher Randall Beharry, Joseph James Elsen, Ralph Lawrence Helmers, Jr., Tamara Jocelyn Kearney, Jeffrey John Kester, Brenda Kay Murphy, Raymond Louis Niehoff, Kathleen Hack Noble, Richard Nicholas Reinhart, Jr., Robert Joseph Sarama, Charles Henry Taylor, Li-Hsin Tsai, Susana Rosa Waimin Siu, Thomas Joseph Wehmeier, Vince York-Leung Wong
  • Patent number: 6827955
    Abstract: The present invention is a high-protein foodstuff that contains at least two layers wherein at least one of the layers contains at least 25% of protein and wherein the high-protein foodstuff may further contains of a high protein coating. The present invention is also directed to methods for making the high protein foodstuff, optionally with a high protein coating.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: December 7, 2004
    Inventor: David J. McCabe