Patents Issued in December 4, 2007
  • Patent number: 7304079
    Abstract: Disclosed are substituted indolealkanoic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.
    Type: Grant
    Filed: September 12, 2006
    Date of Patent: December 4, 2007
    Assignee: The Institute for Pharmaceutical Discovery, LLC
    Inventors: Michael Jones, David Gunn, John Jones, Michael Van Zandt
  • Patent number: 7304080
    Abstract: Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: December 4, 2007
    Assignee: PTC Therapeutics, Inc.
    Inventors: Gary Mitchell Karp, Seongwoo Hwang, Guangming Chen, Neil Gregory Almstead, Young-Choon Moon
  • Patent number: 7304081
    Abstract: The present invention relates to inhibitors of 11-? hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-? hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: December 4, 2007
    Assignee: Incyte Corporation
    Inventors: Wenqing Yao, Jincong Zhuo, Meizhong Xu, Brian W. Metcalf, Chunhong He, Ding-Quan Qian, Colin Zhang
  • Patent number: 7304082
    Abstract: Compounds of this invention are non-peptide, reversible inhibitors of type 2 methionine aminopeptidase, useful in treating conditions mediated by angiogenesis, such as cancer, haemangioma, proliferative retinopathy, rheumatoid arthritis, atherosclerotic neovascularization, psoriasis, ocular neovascularization and obesity.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: December 4, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Joseph P. Marino, Jr., Scott K. Thompson, Daniel Frank Veber
  • Patent number: 7304083
    Abstract: A 2-iminoimidazole derivative represented by the formula: {wherein R1, R2 and R3 represent hydrogen, optionally substituted C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10–R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.}or salt thereof.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: December 4, 2007
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musha, Motoji Kogushi, Tsutomu Kawata, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
  • Patent number: 7304084
    Abstract: 6-[(4,5-Dihydro-1H-imidazol-2-yl)amino-]-7-methyl-1H-benzimidazole-4-carbonitrile substantially free of 2,3,7-triamino-4,6-dimethyl-1,9-phenazinedicarbonitrile, and the anhydrous monoacetate salt thereof, are useful in the treatment of alpha-2 mediated disorders such as ocular hypertension.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: December 4, 2007
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Jared Lynn Randall, Richard Alan Gibbs, Gregory Kent Bosch, Michael David Curtis, Li Sun, Nicholas Nikolaides
  • Patent number: 7304085
    Abstract: Disclosed are compounds, compositions and methods for treating Flaviviridae family virus infections.
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: December 4, 2007
    Assignee: Genelabs Technologies, Inc.
    Inventors: Christopher D. Roberts, Dong-Fang Shi, Ronald C. Griffith
  • Patent number: 7304086
    Abstract: The present invention relates to novel inhibitors of glutaminyl cyclase and combinations thereof for the treatment of neuronal disorders, especially Alzheimer's disease, Down Syndrome, Parkinson disease, Chorea Huntington, pathogenic psychotic conditions, schizophrenia, impaired food intake, sleep-wakefulness, impaired homeostatic regulation of energy metabolism, impaired autonomic function, impaired hormonal balance, impaired regulation, body fluids, hypertension, fever, sleep dysregulation, anorexia, anxiety related disorders including depression, seizures including epilepsy, drug withdrawal and alcoholism, neurodegenerative disorders including cognitive dysfunction and dementia.
    Type: Grant
    Filed: February 4, 2005
    Date of Patent: December 4, 2007
    Assignee: Probiodrug AG
    Inventors: Stephan Schilling, Mirko Buchholz, Andre Johannes Niestroj, Ulrich Heiser, Hans-Ulrich Demuth
  • Patent number: 7304087
    Abstract: Anti-viral agents of Formula (I) wherein: A represents hydroxy; D represents aryl or heteroaryl; E represents hydrogen, C1-6alkyl, aryl, heteroaryl or heterocyclyl; G represents hydrogen or optionally substituted C1-6alkyl; J represents C1-6alkyl, heterocyclylalkyl, arylalkyl or heteroarylalkyl; and salts, solvates and esters thereof; provided that when A is esterified to form —OR where R is selected from straight or branched chain alkyl, aralkyl, aryloxyalkyl, or aryl, then R is other than tert-butyl; processes for their preparation, pharmaceutical compositions comprising them, and methods of using them in HCV treatment are provided.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: December 4, 2007
    Assignee: Glaxo Group Limited
    Inventors: David Haigh, Charles David Hartley, Peter David Howes, Deborah Lynette Jackson, Pritom Shah, Martin John Slater
  • Patent number: 7304088
    Abstract: This invention relates to treating an infection with a virus using protease inhibitors. Examples of the protease inhibitors include compounds of formula (I).
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: December 4, 2007
    Assignee: TaiGen Biotechnology
    Inventors: Syaulan Yang, Jen-Dar Wu, Feng-Yih Su, Chun-Wei Kuo, Wen-Chang Chen, Yibin Xiang, Ching-Cheng Wang, Shao-Ying Liao
  • Patent number: 7304089
    Abstract: Food, feed or drug preparations are described that contain conjugated trans/cis-octadecatrienoic acid, and processes are described for their production. Inventive preparations preferably comprise calendic acid. The invention also relates to the use of the preparations to reduce food intake in humans and animals and to improve food utilization.
    Type: Grant
    Filed: January 16, 2002
    Date of Patent: December 4, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Klaus Krämer, Oliver Hasselwander, Uwe Oberfrank
  • Patent number: 7304090
    Abstract: Fluorescein and derivatives have use in the treatment of a disease of a living animal body, including human, which disease is responsive to the inhibition of the cystic fibrosis transmembrane conductance regulator chloride channels, for instance polycystic kidney disease and secretory diarrhoea.
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: December 4, 2007
    Assignee: The University of Bristol
    Inventors: David Noel Sheppard, Zhiwei Cai
  • Patent number: 7304091
    Abstract: The present invention relates to compounds with structures resembling natural statins isolated from Penicillium sp.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: December 4, 2007
    Assignee: Myco TeO A/S
    Inventors: Jens Christian Frisvad, Lene Lange, Kirk Schnorr, Steen Stender, Thomas Ostenfeld Larsen
  • Patent number: 7304092
    Abstract: The present invention relates to novel compounds, pharmaceutical compositions and methods for treating tumors, cancer and hyperproliferative diseases including psoriasis, genital warts and hyperproliferative cell growth diseases, including hyperproliferative keratinocyte diseases such as hyperkeratosis, ichthyosis, keratoderma or lichen planus.
    Type: Grant
    Filed: November 11, 2003
    Date of Patent: December 4, 2007
    Assignee: Yale University
    Inventors: David J. Austin, Viet-Ahn A. Nguyen, Doris Pupowicz, Albert Deisseroth, Tao Wang, Enrica Lerma
  • Patent number: 7304093
    Abstract: The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising a ketone compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's Disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: December 4, 2007
    Assignee: Esperion Therapeutics, Inc.
    Inventors: Jean-Louis Dasseux, Daniela Carmen Oniciu
  • Patent number: 7304094
    Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: December 4, 2007
    Assignee: Merck Sharp + Dohme
    Inventors: Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Duncan Edward Shaw, Martin Richard Teall, Susannah Williams, Brian John Williams
  • Patent number: 7304095
    Abstract: A photocurable ink for ink-jet printing, including: a photopolymerizable compound; a pigment; and a dispersing agent, wherein the photopolymerizable compound is a radical polymerizable compound; an amine value of the pigment (AMp) is larger than an acid value of the pigment (ACp); and an acid value of the dispersing agent (ACd) is larger than an amine value of the dispersing agent (AMd).
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: December 4, 2007
    Assignee: Konica Minolta Medical & Graphic, Inc.
    Inventors: Satoshi Masumi, Daisuke Ishibashi
  • Patent number: 7304096
    Abstract: There is provided a highly functional one-step light-curing dental adhesive composition i) based on a multifunctional prepolymer mixture of 2,2-bis-[4-(2-hydroxy-3-methacryloyloxypropoxy)phenyl]propane (“Bis-GMA”) and a multifunctional prepolymer formed by substitiuting hydrogen atoms of hydroxyl groups present in Bis-GMA molecules with methacrylate groups, in which the Bis-GMA is used as a base prepolymer of conventional dental adhesive compositions; and ii) comprising and acidic monomer for removing a portion of smear layer, which is allowed to be bonded without separate treatment of acid etchant, an adhesive monomer having both hydrophobic and hydrophilic properties, a hydrophilic monomer which is allowed to be bonded in the present of moisture, an inorganic filler for improving mechanical properties, diluent, water for demineralization, a photoinitiation system and other additives.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: December 4, 2007
    Assignee: Korea Institute of Science and Technology and Dentkist, Inc.
    Inventors: Dong Keun Han, Kyu Hyun Baek, Min Sung Kim, Sang Soon Park, Hyun Chul Goo, Choong Ho Kim
  • Patent number: 7304097
    Abstract: The present invention provides an irradiated crosslinked polyethylene containing reduced free radicals, preferably containing substantially no residual free radical. Disclosed is a process of making irradiated crosslinked polyethylene by irradiating the polyethylene in contact with a sensitizing environment at an elevated temperature that is below the melting point, in order to reduce the concentration of residual free radicals to an undetectable level. A process of making irradiated crosslinked polyethylene composition having reduced free radical content, preferably containing substantially no residual free radicals, by mechanically deforming the polyethylene at a temperature that is below the melting point of the polyethylene, optionally in a sensitizing environment, is also disclosed herein.
    Type: Grant
    Filed: August 16, 2006
    Date of Patent: December 4, 2007
    Assignees: Massachusetts General Hospital, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg, Gareth H. McKinley
  • Patent number: 7304098
    Abstract: The present invention is a composition for forming seals. The composition includes a base material and a hydrogel. The base materials is preferably an elastomer or a thermoplastic. Seals formed with the composition are particularly suited for use in a wellbore environment. The inclusion of hydrogel in the seals allows the seals to be manipulated or altered through certain environmental factors. For instance, temperature, oil/water ratio, pH and the electronic field may all be used to alter the characteristics of the hydrogel. In this way, the seal may be caused to swell in response to a specific stimulus, thereby preventing or sealing a leak without requiring additional work or input from the operator.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: December 4, 2007
    Assignee: Schlumberger Technology Corporation
    Inventors: Yanmei Li, Jian Zhou
  • Patent number: 7304099
    Abstract: The invention relates to an improved system for inkjet printing which results in images with increased permanence as measured by transfer of color from the image when the image is subjected to mechanical and/or chemical abrasion. The invention provides a fusible material that may be combined with any or all of the color inks used to create the image, or it may be used as a colorless fluid applied pre- or post-printing. The permanence of images produced by the system are comparable to those produced by electrophotography. The invention also relates to a printing apparatus that contains a means for fusing the image using heat applied after the printed substrate is ejected from the printer.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: December 4, 2007
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventor: Makarand P Gore
  • Patent number: 7304100
    Abstract: The present invention provides a process for manufacturing a latex coating composition wherein the process comprises a) mixing water with a thickener in a high shear mixing zone to produce a gelled solution and b) mixing said gelled solution with a latex and glass bubbles to produce a latex coating composition. The latex coating compositions exhibit improved waterproofing characteristics and significantly reduce the temperature increase due to solar rays when applied to industrial or architectural surfaces.
    Type: Grant
    Filed: September 22, 2004
    Date of Patent: December 4, 2007
    Assignee: Hyperseal, Inc.
    Inventor: Ronald R. Savin
  • Patent number: 7304101
    Abstract: Anionic species are removed from aqueous dispersions of ionic fluoropolymers using anion exchange resins. In some embodiments, cationic species are also removed using cation exchange resins.
    Type: Grant
    Filed: July 19, 2004
    Date of Patent: December 4, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: Klaus Hintzer, Kai H. Lochhaas, Tanja Zeif, Steven J. Hamrock, Harold T. Freemyer
  • Patent number: 7304102
    Abstract: An encapsulant for use with opto-electronic devices and optical components incorporates a filler made from a glass that has been processed into particle form and heated to a predetermined temperature for a predetermined time, along with an epoxy having an index of refraction matched to that of the glass and heated to a predetermined temperature for a predetermined time, to prevent settling of the filler particles after mixing the filler particles with the epoxy, and thereby obtaining uniform dispersion of the particles within the epoxy. The encapsulant provides for high light transmittance, and its coefficient of thermal expansion can be varied by varying the amount of filler without substantially altering the optical properties of the encapsulant. The coefficient of thermal expansion variation within the encapsulant preferably is less than 30%, due to uniform dispersion of the filler particles within the epoxy.
    Type: Grant
    Filed: December 7, 2004
    Date of Patent: December 4, 2007
    Assignee: Yazaki Corporation
    Inventors: Yongan Yan, Douglas Evan Meyers, Mark Allen Morris, D. Laurence Meixner, Satyabrata Raychaudhuri
  • Patent number: 7304103
    Abstract: The present invention incorporates new processes for blending derivatized carbon nanotubes into polymer matrices to create new polymer/composite materials. When modified with suitable chemical groups using diazonium chemistry, the nanotubes can be made chemically compatible with a polymer matrix, allowing transfer of the properties of the nanotubes (such as mechanical strength) to the properties of the composite material as a whole. To achieve this, the derivatized (modified) carbon nanotubes are physically blended with the polymeric material, and/or, if desired, allowed to react at ambient or elevated temperature. These methods can be utilized to append functionalities to the nanotubes that will further covalently bond to the host polymer matrix, or directly between two tubes themselves.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: December 4, 2007
    Assignee: William Marsh Rice University
    Inventors: James M. Tour, Jeffrey L. Bahr, Jiping Yang
  • Patent number: 7304104
    Abstract: The cement admixture of the present invention can provide viscosity decreasing ability as well as a high dispersing ability and slump loss preventing ability even in a high water reducing ratio range. The above-mentioned cement admixture comprises three components of a copolymer (A) containing a constituent unit (I) derived from the unsaturated (poly)alkylene glycol ether monomer (a) and a constituent unit (II) derived from a maleic acid monomer (b), a specific unsaturated (poly)alkylene glycol ether monomer (a) and a non-polymerizable (poly)alkylene glycol (B) having no alkenyl group.
    Type: Grant
    Filed: March 4, 2004
    Date of Patent: December 4, 2007
    Assignee: Nippon Shokubai Co. Ltd.
    Inventors: Akihiko Yamashita, Hiromichi Tanaka, Toru Uno, Yoshiyuki Onda, Tsuyoshi Hirata
  • Patent number: 7304105
    Abstract: A composite material which comprises an elastomer or vulcanized rubber and particles of a high-density material, such as tungsten, evenly dispersed therein, wherein the contents of the elastomer or vulcanized rubber and the high-density particles are 35 to 50 vol. % and 50 to 65 vol. %, respectively, based on the whole composite material, and the high-density particles have a particle composition comprising 60 to 80 vol. % coarse particles having a particle diameter of 10 to 100 ?m, 10 to 20 vol. % medium particles having a particle diameter of 3 to 6 ?m, and 10 to 20 vol. % fine particles having a particle diameter of 1 to 2 ?m, the spaces among the coarse particles being filled with the medium particles and fine particles. The composite material is excellent in flexibility and processability and is suitable for use as a radiation-shielding sheet material, weight member, vibration-damping material, balancing member, radiating material, and shot material.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: December 4, 2007
    Assignee: Nippon Tungsten Co., Ltd.
    Inventors: Yasunao Kai, Masahiro Yamauchi, Kenji Okamura
  • Patent number: 7304106
    Abstract: A nanocomposite precursor comprises a plurality of nanoparticles homogeneously dispersed in an organic binder precursor. The nanocomposite precursor is useful for forming a nanocomposite, suitable for use as a protective coating, wherein the plurality of nanoparticles is homogeneously dispersed in an organic binder. The nanoparticles comprise Ti/Sb mixed oxide nanoparticles containing a rutile-like crystalline phase, wherein the ensemble average rutile-like crystalline phase content of the Ti/Sb mixed oxide nanoparticles is at least 20 weight percent, and wherein the weight ratio of antimony to titanium in the Ti/Sb mixed oxide nanoparticles is in a range of from at least 0.42 up to and including 2.93.
    Type: Grant
    Filed: August 10, 2004
    Date of Patent: December 4, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: John T. Brady, David S. Arney
  • Patent number: 7304107
    Abstract: Toughened poly(ethylene terephthalate) compositions which contain functionalized polymeric tougheners, and wherein the poly(ethylene terephthalate) contains little or no antimony, have superior heat stability and retain their toughness for longer periods at higher temperatures. The compositions are useful for molded and shaped parts, such as mechanical parts, automotive parts and electrical parts.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: December 4, 2007
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Gregory R. Alms, Toshikazu Kobayashi
  • Patent number: 7304108
    Abstract: A vinyl polymer having, at a molecular chain terminus, a structure represented by the general formula 1: (wherein R3 is a hydroxy, amino, epoxy, carboxylic acid, ester, ether, amide or silyl group, an alkenyl group having low polymerizability, an organic compound having 1 to 20 carbon atoms, X is a halogen atom, a nitroxide or sulfide group or a cobalt porphyrin complex).
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: December 4, 2007
    Assignee: Kaneka Corporation
    Inventors: Yoshiki Nakagawa, Kenichi Kitano, Masayuki Fujita, Nao Fujita
  • Patent number: 7304109
    Abstract: The present invention provides a rubber composition, in which abrasion resistance and gripping performance are improved in a balanced manner and bleeding of the components is inhibited, and a tire using the composition. Specifically, the present invention provides a rubber composition comprising (B) 10 to 200 parts by weight of a low molecular weight aromatic vinyl-conjugated diene copolymer having weight average molecular weight of 1.0×103 to 1.0×105 and aromatic vinyl content of 10 to 75% by weight, wherein the hydrogenation ratio of double bonds in the conjugated diene part is 20 to 60%, based on (A) 100 parts by weight of a rubber component containing at least 60% by weight of a styrene-butadiene copolymer having weight average molecular weight of 5.0×105 to 2.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: December 4, 2007
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Kazuyuki Nishioka, Takahiro Mabuchi, Katsumi Terakawa, Kiyoshige Muraoka
  • Patent number: 7304110
    Abstract: This invention provides a production method of a vinyl polymer having a functional group at a molecular chain terminus which comprises adding a compound (I) having a functional group and an internal alkenyl group or conjugated polyene compound (II) in the living radical polymerization of a radical-polymerizable vinyl monomer. The present invention relates to a vinyl polymer having a functional group at a molecular terminus, a production method of the same and a curable composition containing said polymer.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: December 4, 2007
    Assignee: Kaneka Corporation
    Inventors: Yoshiki Nakagawa, Kenichi Kitano, Nao Fujita
  • Patent number: 7304111
    Abstract: A problem of the invention is to provide a propylene copolymer which is excellent in adhesion to crystalline propylene-based polymers and which is excellent in solubility and compatibility with polar resins, a process for producing the same, and a composition containing the subject polypropylene copolymer. The invention is concerned with a polypropylene copolymer, which is characterized by having a polymer principal chain (A) derived from a propylene-based polymer having (1) a prescribed requirement as defined by the 13C-NMR spectral measurement and having (2) a melting point [Tm] by a differential scanning calorimeter of not higher than 100° C., or a crystal melting heat of less than 5 J/g; and a side chain containing a polymer chain (B) which is different from the principal chain, with a weight ratio of (A)/(B) being in the range of from 20/1 to 1/20, a composition containing the subject copolymer, and a process for producing the subject copolymer.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: December 4, 2007
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Masato Onoe, Kazuyuki Hata
  • Patent number: 7304112
    Abstract: A curable composition is described comprising a Michael donor component, a polyacryl component, and 1) an ethylenically unsaturated monomer having a reactive azlactone functional group, or 2) an ethylenically unsaturated monomer having a reactive ring-opened azlactone functional group. A telechelic polymer that is the reaction product of these components is also described.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: December 4, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: Kevin M. Lewandowski, Duane D. Fansler, Babu N. Gaddam
  • Patent number: 7304113
    Abstract: The invention relates to a method for partially and selectively hydrogenating a polymer made of at least a conjugated diene monomer having a vinyl content of from 20 to 65%, comprising a hydrogenation step on a solution of the polymer, characterized in that the hydrogenation step is performed in the presence of an iron-containing catalyst whereby a hydrogenated polymer is obtained wherein the vinyl content is reduced to 5% or less, whereas the content of 1,4-double bonds is maintained at a level of at least 30%.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: December 4, 2007
    Assignee: Kraton Polymers U.S. LLC
    Inventors: Henk van de Weg, Mark Hageman
  • Patent number: 7304114
    Abstract: Liquid rubbers that are ordinarily immiscible in liquid thermoset resins can be made miscible by the addition of at least one non-functional aromatic end-group to the polymer chains of such liquid rubber compositions. Such addition may be initiated by high-temperature peroxides in non-functional aromatic solvents. The liquid rubbers are found to improve the fracture toughness of cured thermoset resins while maintaining dimensional and heat resistance.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: December 4, 2007
    Assignee: Rohm and Haas Company
    Inventor: Edward Ewart LaFleur
  • Patent number: 7304115
    Abstract: Provided is a method of manufacturing a perhalogenated elastomer comprising using an onium compound to coagulate a latex comprising polymer particles, the polymer particles consisting essentially of interpolymerized units of one or more perhalogenated comonomer(s) and at least one cure site monomer, wherein the coagulation is performed essentially free of metal ions and metal salts. Also provided is an elastomeric composition comprising a curable perhalogenated elastomer comprising interpolymerized units derived from a nitrogen-containing cure site monomer and coagulated with an onium compound, wherein the elastomer is capable of curing without adding further components and wherein the composition is essentially free of metal ions and metal salts. Also provided are fluoropolymer articles and methods of making fluoropolymer compositions and articles.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: December 4, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: Guy Van Gool, Alain Verschuere, Werner M. A. Grootaert
  • Patent number: 7304116
    Abstract: A braided comb-shaped salt-resistant thickening agent for tertiary oil extraction from class I oil reservoir is disclosed. The agent is polymerized with monomer (A) and monomer (B), and monomer (A) is one or multiple water soluble non-saturated compound(s) with alkenyl chain, while monomer (B) is at least one compound with the following formula: Monomer (A) is preferably acrylamide, ethenyl pyrrolidone, 2-acrylamide-2 methylpropane sulfonic acid, and acrylic acid or the mixture of the above said compounds, and in the formula of monomer (B), A is COOH, OH, SO3H, R1 and R2 are H or C1-C12 alkyl, R3 and R4 represent C1-C12 alkyl, C1-C12 alkylaryl, C1-C12 alkyl ether or C1-C12 alkyl ester group. This thickening agent has fine water solubility and good property to thicken water medium. The polymer's molecules present a braided comb-shaped structure in water solution with fine salt-resistant performances.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: December 4, 2007
    Assignee: Petrochina Company Limited
    Inventors: Shiyi Yuan, Jianhui Luo, Ruoying Pu, Yuzhang Liu, Huaijiang Zhu, Pingmei Wang, Chunming Xiong, Ying Zhang, Fengluan Bai, Jingbo Yang
  • Patent number: 7304117
    Abstract: Novel azo-based reactive yellow dyes and a process for manufacturing and using ocular devices having blue light absorption properties. Intraocular lenses so produced block blue light from reaching the retina of an eye implanted with the IOL. By blocking blue light from reaching the retina, the IOL thereby prevents potential damage to the retina.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: December 4, 2007
    Assignee: Bausch & Lomb Incorporated
    Inventor: Yu-Chin Lai
  • Patent number: 7304118
    Abstract: An ethylene-based copolymer for non-crosslinked water supply pipe is provided. The ethylene-based copolymer is prepared using a supported hybrid metallocene catalyst and has a dimodal or broad molecular weight distribution. The ethylene-based copolymer has a high density molecular structure in a low molecular weight and has a low density molecular structure with high content of a comonomer in a high molecular weight. The ethylene-based copolymer has a molecular weight distribution of 5-30 and the distribution of copolymerization of ethylene and C3-20 ?-olefin is localized in high molecular weight chains. Accordingly, the ethylene-based copolymer has superior processability, internal pressure creep resistance at high temperatures and environmental stress crack resistance.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: December 4, 2007
    Assignee: LG Chem, Ltd.
    Inventors: Ki Soo Lee, Choong Hoon Lee, Sangwoo Lee, Eunjung Lee, Soojeong Lee, Seungwoo Choi
  • Patent number: 7304119
    Abstract: The invention relates to radically copolymerizable acetophenone or benzophenone derivatives, which may be obtained by reacting a) acrylic or methacrylic compounds, which contain at least one isocyanate-reactive group [compounds a)], with b) compounds, which contain at least two isocyanate groups [compounds b)] and c) acetophenone or benzophenone derivatives, which contain at least one isocyanate-reactive group [compounds c)]. Said invention also relates to copolymers, which contain said copolymerizable photoinitiators, as well as to the use of said copolymers in UV-crosslinkable substances, in particular hot-melt pressure-sensitive adhesives.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: December 4, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Wolf-Dieter Balzer, Ulrich Erhardt, Volker Ladenberger, Harald Meyer, Bernd Bruchmann, Karl-Heinz Schumacher
  • Patent number: 7304120
    Abstract: An epoxy compound, represented by a general formula (I) is obtained by reacting an anthrahydroquinone compound having a following general formula (II) with epihalohydrin. (wherein R1-R10 each represent hydrogen atom or alkyl group having 1-6 carbon atoms, and n represents an integer of 0 or more, and wherein A1, A2 each represent hydrogen atom or alkali metal atom, R1-R10 each represent hydrogen atom or alkyl group having 1-6 carbon atoms.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: December 4, 2007
    Assignee: Japan Epoxy Resins Co., Ltd.
    Inventors: Atsuhito Hayakawa, Akihiro Itou
  • Patent number: 7304121
    Abstract: The present invention provides a liquid-crystalline polyester obtainable by a method comprising the steps of: (1) preparing a prepolymer consisting of the repeating units represented by formulae (I), (II), (III) and (IV): wherein, p, q, r and s represent relative molar proportions (mol %) of the repeating units in the liquid-crystalline polyester resin and satisfy the following formulae: 60?p?80, 10?r?20, 10?q+s?20, 0.05?s/(q+s)?0.3, p+q+r+s=100; and (2) heating the prepolymer in substantially solid state at 250-350° C., provided that the liquid crystalline polyester has a deflection temperature under load of 280-340° C., and a melt viscosity of 10-60 Pa·s.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: December 4, 2007
    Assignee: Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo
    Inventors: Hiroyuki Kato, Motoki Asahara, Tetsuhide Sawada
  • Patent number: 7304122
    Abstract: The present invention provides elastomeric copolyester amides, elastomeric copolyester urethanes, and methods for making the same. The polymers that are based on ?-amino acids and possess suitable physical, chemical and biodegradation properties. The polymers are useful as carriers of drugs or other bioactive substances. The polymers can be linked, intermixed, or a combination thereof, to one or more drugs.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: December 4, 2007
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Chih-Chang Chu, Ramaz Katsarava
  • Patent number: 7304123
    Abstract: In one aspect, the invention relates to processes for producing substantially free-flowing shapes of macrocyclic oligoester, wherein the freshly-shaped macrocyclic oligoester is maintained at elevated temperature for a sufficient time. In certain embodiments, the shapes are heated in water, thereby avoiding agglomeration during the heating process itself. In another aspect, the invention relates to processes for removing solvent from a solution of macrocyclic oligoester using elevated temperature, reduced pressure, or both, thereby obviating the need for an anti-solvent to precipitate the macrocyclic oligoester from the solution. Other aspects of the invention related to shaping of macrocyclic oligoesters are presented as well.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: December 4, 2007
    Assignee: Cyclics Corporation
    Inventors: Timothy A. Thompson, Peter D. Phelps, Steven J. Winckler
  • Patent number: 7304124
    Abstract: A stripping process is provided which continuously strips volatile substances from a dispersion containing a polymer particles through stripping the volatile substances from a dispersion by blowing an inert gas into the dispersion to draw the volatile substances into the inert gas, removing the volatile substances from the gas mixture of the inert gas and the stripped volatile substances and circulating the purified inert gas obtained by removing the volatile substances from the gas mixture, and blowing the purified inert gas into the dispersion. Also provided is a production process for a toner which uses this stripping process.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: December 4, 2007
    Assignee: Zeon Corporation
    Inventors: Takeo Fujino, Kazuhiro Sato
  • Patent number: 7304125
    Abstract: A process for manufacturing a polymer having a molecular weight in excess of 5,000, and preferably in excess of 40,000, comprises, producing a polymerized reaction mass in which the polymer is dispersed, the reaction mass including solvent(s), unreacted monomer and other unwanted contaminants; feeding the reaction mass to a means for disentangling the polymer's molecules to produce a modified polymer in the reaction mass; feeding the modified polymer in the reaction mass to a polymer-recovering means; removing the unwanted volatiles and other byproducts; and, recovering a high molecular weight substantially pure modified polymer having substantially the same molecular weight as the polymer fed to the disentangling means and a viscosity at least 10% lower than that of the polymer fed to the disentangling means.
    Type: Grant
    Filed: February 12, 2005
    Date of Patent: December 4, 2007
    Assignee: Stratek Plastic Limited
    Inventor: Jean-Pierre Ibar
  • Patent number: 7304126
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: December 4, 2007
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • Patent number: 7304127
    Abstract: The present invention provides, among other things, a polypeptide that binds with the gp120 envelope protein of HIV, in particular HIV-1, under physiological conditions, a nucleic acid that encodes such a polypeptide and can be expressed in a cell, a composition comprising such a polypeptide or nucleic acid or an antibody and a carrier therefor, a composition comprising a solid support matrix to which is attached an above-described polypeptide or an anti-antibody to a specified polypeptide sequence, a method of making an antibody to gp120, and a method of removing HIV from a bodily fluid.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: December 4, 2007
    Assignee: United States of America as represented by the Secretary, Department of Health and Human Services
    Inventor: Carl Saxinger
  • Patent number: 7304128
    Abstract: Peptides have been generated that have binding affinity to carbon nanostructures and particularly carbon nanotubes. Peptides of or the invention are generally about twelve amino acids in length. Methods for generating carbon nanotube binding peptides are also disclosed.
    Type: Grant
    Filed: June 3, 2003
    Date of Patent: December 4, 2007
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Anand Jagota, Steven Raymond Lustig, Siqun Wang