Patents Issued in November 18, 2008
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Patent number: 7452823Abstract: An etching method, for selectively etching a silicon nitride film to a silicon oxide film by using a processing gas in a processing chamber including an electrode therein, includes the steps of mounting a target object having the silicon oxide film and the silicon nitride film onto the electrode and etching the silicon nitride film by introducing a gaseous mixture containing CF4 gas, H2 gas and N2 gas as a processing gas into the processing chamber and applying a high frequency power of 0.20 W/cm2 or less to the electrode while maintaining a pressure in the processing chamber to be equal to or smaller than 4 Pa.Type: GrantFiled: March 7, 2006Date of Patent: November 18, 2008Assignee: Tokyo Electron LimitedInventor: Manabu Sato
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Patent number: 7452824Abstract: The invention involves a method of characterizing a plasma reactor chamber through the behavior of many selected plasma parameters as functions of many selected chamber parameters. The plasma parameters may be selected from a group including ion density, wafer voltage, etch rate and wafer current or other plasma parameters. The chamber parameters are selected from a group including source power, bias power, chamber pressure, magnetic coil current in different magnetic coils, gas flow rates in different gas injection zones and species composition of the gas in different gas injection zones.Type: GrantFiled: December 11, 2006Date of Patent: November 18, 2008Assignee: Applied Materials, Inc.Inventors: Daniel J. Hoffman, Ezra Robert Gold
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Patent number: 7452825Abstract: In the method of forming a mask structure, a first mask is formed on a substrate where the first mask includes a first mask pattern having a plurality of mask pattern portions having openings therebetween and a second mask pattern having a corner portion of which an inner side wall that is curved. A sacrificial layer is formed on the first mask. A hard mask layer is formed on the sacrificial layer. After the hard mask layer is partially removed until the sacrificial layer adjacent to the corner portion is exposed, a second mask is formed from the hard mask layer remaining in the space after removing the sacrificial layer. A minute pattern having a fine structure may be easily formed on the substrate.Type: GrantFiled: October 30, 2006Date of Patent: November 18, 2008Assignee: Samsung Electronics Co., Ltd.Inventors: Doo-Youl Lee, Han-Ku Cho, Suk-Joo Lee, Gi-Sung Yeo, Cha-Won Koh, Sung-Gon Jung
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Patent number: 7452826Abstract: An oxidation method is capable of forming oxide films in an improved interfilm thickness uniformity. The oxidation method includes the steps of supplying an oxidizing gas and a reducing gas into a processing vessel 22 capable of being evacuated and holding a plurality of workpieces W arranged at predetermined pitches, and creating a process atmosphere containing active oxygen species and active hydroxyl species in the processing vessel 22 through the interaction of the oxidizing gas-and the reducing gas. At least either of the oxidizing gas and the reducing gas is jetted into an upstream region S1, a middle region S2 and a downstream region S3, with respect to the flowing direction of the gas, of a processing space S containing the workpieces W.Type: GrantFiled: August 11, 2006Date of Patent: November 18, 2008Assignee: Tokyo Electron LimitedInventors: Kazuhide Hasebe, Kota Umezawa, Yutaka Takahashi
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Patent number: 7452827Abstract: A method of processing a semiconductor workpiece. The method includes flowing a process gas to a semiconductor workpiece through a first plurality of orifices positioned in a gas distribution faceplate. The method also includes removing gas from over the semiconductor workpiece through a chamber exhaust port and a second plurality of orifices positioned in the gas distribution faceplate.Type: GrantFiled: June 13, 2006Date of Patent: November 18, 2008Assignee: Applied Materials, Inc.Inventors: Steven Gianoulakis, Karthik Janakiraman
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Patent number: 7452828Abstract: To provide a carbon nanotube device capable of efficiently exerting various electrical or physical characteristics of a carbon nanotube, the present invention provides: a carbon nanotube device, in which a carbon nanotube structure layer having a network structure in which plural carbon nanotubes mutually cross-link, is formed in an arbitrary pattern on a surface of a base body; and a method of manufacturing the carbon nanotube device with which the carbon nanotube can be suitably manufactured.Type: GrantFiled: October 27, 2003Date of Patent: November 18, 2008Assignee: Fuji Xerox Co., Ltd.Inventors: Masaki Hirakata, Takashi Isozaki, Kentaro Kishi, Taishi Shigematsu, Chikara Manabe, Kazunori Anazawa, Hiroyuki Watanabe, Masaaki Shimizu
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Patent number: 7452829Abstract: In a process of forming a silicon oxide film 116 that constitutes an interlayer insulating film with TEOS as a raw material through the plasma CVD method, the RF output is oscillated at 50 W, and the RF output is gradually increased from 50 W to 250 W (an output value at the time of forming a film) after discharging (after the generation of O2-plasma). A TEOS gas is supplied to start the film formation simultaneously when the RF output becomes 250 W, or while the timing is shifted. As a result, because the RF power supply is oscillated at a low output when starting discharging, a voltage between the RF electrodes can be prevented from changing transitionally and largely.Type: GrantFiled: June 29, 2006Date of Patent: November 18, 2008Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Shunpei Yamazaki, Masaaki Hiroki, Mitsunori Sakama
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Patent number: 7452830Abstract: Semiconductor devices and methods for manufacturing the same are disclosed. An example method includes loading a first substrate to be provided with an oxynitride layer along with a second substrate having a nitride layer in a boat, and forming the oxynitride layer on the first substrate by placing the boat into a furnace and thermally treating the boat under an oxygen atmosphere.Type: GrantFiled: July 27, 2005Date of Patent: November 18, 2008Assignee: Dongbu Electronics Co., Ltd.Inventors: Chul-Ho Shin, Tae-Hong Kim
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Patent number: 7452831Abstract: The filter fabric containing polyphenylene sulfide fibers, characterized in that the following (1) and/or (2) is satisfied is used to provide a filter fabric and a bag filter composed of the filter fabric excellent in dust-collecting efficiency and high in mechanical strength: (1) Containing at least two webs, one of which on the dust side contains 50 wt % or more of heat resistant fibers with a fiber, diameter of 15 ?m or less, while the other web on the clean side contains 50 wt % or more of heat resistant fibers with a fiber diameter of 20 ?m or more (2) Containing a web containing polyphenylene sulfide staple fibers with their fineness kept in a range from 1 to 3 dtex and fluorine-based staple fibers with their fineness kept in a range from 2 to 4 dtex.Type: GrantFiled: March 25, 2004Date of Patent: November 18, 2008Assignee: Toray Industries, Inc.Inventors: Kenko Yamada, Motoki Nagase
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Patent number: 7452832Abstract: A full-surface bonded multiple component nonwoven fabric is provided that has an improved combination of tear strength and tensile strength at lower thicknesses than known in the art. The full-surface bonded multiple component webs have a void percent between about 3% and 56% and a Frazier permeability of at least 0.155 m3/min-m2. The full-surface bonded multiple component nonwoven fabrics can be prepared in a smooth-calendering process.Type: GrantFiled: December 9, 2004Date of Patent: November 18, 2008Assignee: E.I. du Pont de Nemors and CompanyInventors: Vishal Bansal, Hyun Sung Lim, David Matthews Laura, Jr.
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Patent number: 7452833Abstract: A heat reflective garment interlining laminate is provided that includes a continuous filament layer and a metallized thermoplastic film. The laminate is characteristically low-cost and suitable for such apparel applications as sports clothing, military clothing, camping gear, hunting/fishing clothing, and the like.Type: GrantFiled: August 30, 2005Date of Patent: November 18, 2008Assignee: Polymer Group, Inc.Inventors: Robert Daniel Russell, Chris Haas
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Patent number: 7452834Abstract: A fibrous sheet containing cotton fibers and at least two kinds of synthetic fibers is disclosed. The synthetic fibers form a nonwoven fabric. The cotton fibers enter a fiber network of the nonwoven fabric and interlace with the fiber network thereby to form a cotton fiber layer on one side of the nonwoven fabric, with part of the cotton fiber layer entering the nonwoven fabric. The synthetic fibers contain a combination of heat fusible fiber (a) and heat fusible fiber (b) having a small thickness than the fiber (a) or a combination of the fiber (a) and a fiber (c) that is not thermally bonded with the fiber (a).Type: GrantFiled: April 6, 2004Date of Patent: November 18, 2008Assignee: Kao CorporationInventor: Shinsuke Nagahara
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Patent number: 7452835Abstract: A nonwoven blanket embodying the principles of the present invention includes at least two layers, wherein a first layer comprises a spunlace fabric that exhibits one or more raised regions within the fabric. The blanket of the present invention also includes a second durable and protective layer comprising one or more layers of spunmelt fabrics, typically referred to as spunbond and meltblown fabrics. The two layers are mechanically bonded via one or more methods known in the art so as to form at least one or more insulative air pockets within the blanket.Type: GrantFiled: January 19, 2006Date of Patent: November 18, 2008Assignee: PGI Polymer, Inc.Inventor: Cliff Bridges
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Patent number: 7452836Abstract: Lithium silicate materials are described which can be easily processed by machining to dental products without undue wear of the tools and which subsequently can be converted into lithium silicate products showing high strength.Type: GrantFiled: February 6, 2006Date of Patent: November 18, 2008Assignee: Ivoclar Vivadent AGInventors: Elke Apel, Wolfram Höland, Marcel Schweiger, Christian van t'Hoen, Harald Bürke, Volker M. Rheinberger
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Patent number: 7452837Abstract: A method for producing composite ceramic material is provided wherein a core ceramic structure is produced and simultaneously enveloped with a sleeve of similar material.Type: GrantFiled: January 22, 2001Date of Patent: November 18, 2008Assignee: UChicago Argonne, LLC.Inventors: Kenneth C. Goretta, Dileep Singh, Bryant J. Polzin, Terry Cruse, John J. Picciolo
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Patent number: 7452838Abstract: This invention relates to efficiently regenerating catalyst particles by minimizing the formation of localized “hot spots” and “cold spots” in a regeneration zone. In one embodiment, the invention includes mixing spent catalyst from a reactor and cold catalyst from a catalyst cooler in a mixing zone and directing the mixed catalyst to the regeneration zone in a fluidized manner with a fluidizing medium. In the regeneration zone, the mixed catalyst contacts an oxygen-containing regeneration medium under conditions effective to regenerate the spent catalyst contained therein.Type: GrantFiled: March 2, 2005Date of Patent: November 18, 2008Assignee: ExxonMobil Chemical Patents Inc.Inventors: Brian A. Cunningham, Todd R. Steffens, James H. Beech, Jr., Richard E. Walter
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Patent number: 7452839Abstract: The sulfur content of liquid cracking products, especially the cracked gasoline, of the catalytic cracking process is reduced by the use of a sulfur reduction catalyst composition comprising a porous molecular sieve which contains a metal in an oxidation state above zero within the interior of the pore structure of the sieve as well as a rare earth component which enhances the cracking activity of the cracking catalyst. The molecular sieve is normally a faujasite such as USY. The primary sulfur reduction component is normally a metal of Period 3 of the Periodic Table, preferably vanadium. The rare earth component preferably includes cerium which enhances the sulfur reduction activity of the catalyst. The sulfur reduction catalyst may be used in the form of a separate particle additive or as a component of an integrated cracking/sulfur reduction catalyst.Type: GrantFiled: December 16, 2004Date of Patent: November 18, 2008Assignee: W. R. Grace & Co.-Conn.Inventors: Wu-Cheng Cheng, Terry G. Roberie, Hye Kyung Cho Timken, Scott Kevin Purnell, Xinjin Zhao
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Patent number: 7452840Abstract: The present invention relates to agglomerated zeolitic adsorbents containing zeolite X and an inert binder, the inert binder containing at least 80% by weight of clay which has undergone zeolitization by the action of an alkaline solution, the zeolite X having with an Si/Al ratio such that 1.15<Si/Al?1.5, at least 90% of the exchangeable cationic sites of the zeolite X of which are occupied either by barium ions alone or by barium ions and potassium ions whose Dubinin volume is greater than or equal to 0.240 cm3/g. They are obtained by agglomerating zeolite powder with a binder, followed by the zeolitization of the binder, the exchange of the ions of the zeolite by barium ions (and potassium ions) and the activation of the adsorbents thus exchanged.Type: GrantFiled: March 28, 2005Date of Patent: November 18, 2008Assignee: Institut Francais du PetroleInventors: Dominique Plee, Alain Methivier
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Patent number: 7452841Abstract: Mixed ketones are prepared from a mixture of carboxylic acids in a process with high selectivity by using an improved catalyst. The catalyst contains zirconium dioxide or zirconium dioxide and titanium dioxide, and a Group 1 or 2 metal silicate or phosphate salt. The new catalyst is more selective toward the formation of the mixed ketone, as opposed to a symmetrical ketone.Type: GrantFiled: September 22, 2006Date of Patent: November 18, 2008Assignee: Eastman Chemical CompanyInventors: Alexey V. Ignatchenko, Michelle Manichanh King, Zhufang Liu, Calvin W. Whiddon
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Patent number: 7452842Abstract: A porous preform (carrier) is soaked in an impregnating solution, which contains both of a catalytic-activity constituent, e.g. Ni and/or Co, and a carrier-forming constituent, e.g. Mg, Al, Zr, Ti and/or Ca, so as to simultaneously infiltrate the catalytic-activity and carrier-forming constituents into the porous preform. The impregnated preform is dried, calcined at a temperature of 700° C. or higher and then activated at a temperature of 500° C. or higher, whereby fine catalytic-activity particles are distributed on a surface of the porous carrier with high dispersion. Due to finely-distributed catalytic-activity particles, the surface of the catalyst is prevented from deposition of carbonaceous matters during reformation of hydrocarbon and held in an active state over a long term.Type: GrantFiled: October 3, 2003Date of Patent: November 18, 2008Assignee: Japan Oil, Gas and Metals National CorporationInventors: Toshiya Wakatsuki, Kiyoshi Inaba, Hideyuki Nakajima, Eiichi Hosoya
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Patent number: 7452843Abstract: In one embodiment, an exhaust treatment device includes: a substrate, a shell disposed around the substrate, and a retention material disposed between the shell and the substrate. The substrate includes a catalyst that includes a precious metal and a solid solution comprising solid solution metals, wherein the solid solution metals include yttrium, zirconium, and titanium.Type: GrantFiled: December 29, 2003Date of Patent: November 18, 2008Assignee: Umicore AG & Co. KGInventors: William J. LaBarge, Joseph V. Bonadies, Joachim Kupe
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Patent number: 7452844Abstract: The Fischer-Tropsch catalyst of the present invention is a transition metal-based catalyst having a high surface area, a smooth, homogeneous surface morphology, an essentially uniform distribution of cobalt throughout the support, and a small metal crystallite size. In a first embodiment, the catalyst has a surface area of from about 100 m2/g to about 250 m2/g; an essentially smooth, homogeneous surface morphology; an essentially uniform distribution of metal throughout an essentially inert support; and a metal oxide crystallite size of from about 40 ? to about 200 ?. In a second embodiment, the Fischer-Tropsch catalyst is a cobalt-based catalyst with a first precious metal promoter and a second metal promoter on an aluminum oxide support, the catalyst having from about 5 wt % to about 60 wt % cobalt; from about 0.0001 wt % to about 1 wt % of the first promoter, and from about 0.01 wt % to about 5 wt % of the second promoter.Type: GrantFiled: May 8, 2001Date of Patent: November 18, 2008Assignee: Süd-Chemie IncInventors: X. D. Hu, Patrick J. Loi, Robert J. O'Brien
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Patent number: 7452845Abstract: The invention concerns a method for preparing organic-inorganic hybrid materials with controlled porosity and functionality comprising hydrolysis and condensation polymerization of a compound of formula (I): Z-R1—Si(OR)(OR?)(OR?), with an alkaline or alkaline-earth silicate in a mol ratio of (I)/(silicate)=1:9, in the presence of a non-ionic surfactant, to form a mesoporous silica represented by Z-R1—SiO1.5 9 SiO2, whereon is then anchored an organic compound, represented by (?)N—H, comprising a —NH— group capable of reacting with Z, to form a functionalized mesoporous silica represented by (?)N—R—SiO1.5 9 SiO2, which is optionally complexed with a metallic cation to form an organometallic complex. The invention also concerns the use of these materials to separate gases.Type: GrantFiled: March 21, 2002Date of Patent: November 18, 2008Assignee: Centre National de la Recherche ScientifiqueInventors: Robert Corriu, Ahmad Mehdi, Catherine Reye, Henry Ledon, Roger Guilard, Stéphane Brandes, Chloé Thieuleux
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Patent number: 7452846Abstract: A desulfurization system employing a system of fluidizable and circulatable solid particles to desulfurize a hydrocarbon-containing fluid in a fluidized bed reactor. The solid particulate system includes solid sorbent particles operable to remove sulfur from the hydrocarbon-containing fluid stream and solid catalyst particles operable to enhance the octane of the resulting desulfurized hydrocarbon-containing fluid stream. The solid particulate system can be circulated between a reactor, regenerator, and reducer, to thereby allow for substantially continuous desulfurization in the reactor.Type: GrantFiled: May 22, 2007Date of Patent: November 18, 2008Assignee: China Petroleum & Chemical CorporationInventors: Edward L. Sughure, II, Bobby G. Cockrell, Glenn W. Dodwell, Brent J. Bertus
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Patent number: 7452847Abstract: A reversible thermosensitive recording medium including a substrate, and a thermosensitive layer including an electron donating coloring compound, an electron accepting compound, and a phenol anti-oxidation agent containing one or more sulfur atoms having an alkyl group on one side. In addition, the thermosensitive layer reversibly changes its color tone depending on temperature to reversibly record and erase an image thereon.Type: GrantFiled: November 1, 2005Date of Patent: November 18, 2008Assignee: Ricoh Company, Ltd.Inventors: Hiroki Kuboyama, Satoshi Arai, Tadafumi Tatewaki, Satoru Sampei
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Patent number: 7452848Abstract: Certain substituted amines, alkylenediamines or polyamines, and derivatives of these, are suitable for use in preventing, inhibiting, or otherwise modifying crystalline gas hydrate formation. These inhibitors include compounds from any of the following groups. The substituents R1-R5 may be hydrocarbyl groups or, in some cases, polyhydroxyalkyl groups or (CH2)p—COO? in which p is either 1 or 2.Type: GrantFiled: April 26, 2005Date of Patent: November 18, 2008Assignee: Air Products and Chemicals, Inc.Inventors: Ingrid Kristine Meier, Richard Joseph Goddard, Michael Edward Ford
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Patent number: 7452849Abstract: A silicone MQ resin based composition provides the oil industry with Fluid Loss Control (FLC) additives for water based drilling muds which are non-damaging. The composition is capable of achieving zero fluid seepage through filter cake, and a short build time for the initial filter cake, while not reducing the return flow of oil from producing formations. The composition is stable in saturated salt at 120° C. and elevated pressures. The composition comprises solid particles of silicone resin with a glass transition temperature more than 70° C., and it contains solid particles of silicone resin with a particle size distribution in which ( ) at least 90 volume percent of solid particles of silicone resin have an average major axis diameter of 40 ?m or less than 40 ?m, and (ii) at least 10 volume percent of solid particles of silicone resin have an average major axis diameter of 2 ?m or less.Type: GrantFiled: July 31, 2003Date of Patent: November 18, 2008Assignee: Dow Corning CorporationInventors: Vicki Lynn Berry, Julie Lyn Cook, Susan J. Gelderbloom, Diane Marie Kosal, Donald Taylor Liles, Charles W. Olsen, Jr., Christian Francis C. Rome
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Patent number: 7452850Abstract: Disclosed are a lubricant composition obtained by adding a buffer particles having an average particle diameter D1 of 50 ?m<D1?300 ?m to a lubricant, a speed reduction gear filled with the lubricant composition, and an electric power steering apparatus having the speed reduction gear incorporated therein, and noise produced in the speed reduction gear can be made lower than ever before irrespective of the magnitude of backlash in a case where a worm and a worm wheel are combined with each other and without complicating the configuration of the speed reduction gear by the buffer action of the buffer particles added to the lubricant composition, thereby making it possible to reduce noise produced in an automobile caused by the electric power steering apparatus at low cost.Type: GrantFiled: September 25, 2003Date of Patent: November 18, 2008Assignee: Jtekt CorporationInventors: Kouji Kitahata, Fumiaki Kasahara, Naoki Uchida, Noritake Ookawa, Hiroaki Murakami
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Patent number: 7452851Abstract: Lubricant compositions having improved anticorrosion performance comprising an extreme pressure compound comprising a sulfur-containing compound, an antiwear compound comprising a phosphorous-containing compound, an alkylene amine friction modifying compound, a dispersant compound containing basic nitrogen, and a diluent or base oil as applicable, wherein any of compounds other than the diluent or base oil can be the same or different compounds. These lubricant compositions provide improved anticorrosion resistance and fatigue performance, which prolongs service lives of lubricated parts, especially those used in outdoor applications.Type: GrantFiled: October 24, 2003Date of Patent: November 18, 2008Assignee: Afton Chemical CorporationInventors: Mark T. Devlin, Helen T. Ryan
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Patent number: 7452852Abstract: Paint residues may be removed from spraying equipment and the like by flushing with aqueous compositions containing alkoxylated aromatic alcohols wherein the aromatic ring moieties of such alcohols do not bear any alkyl substituent containing more than 4 carbon atoms. Preferably, the aqueous compositions also contain an alkanolamine or other base. The alkoxylated aromatic alcohols contain an average of at least about 2 oxyalkylene moieties (preferably, oxyethylene moieties) per molecule.Type: GrantFiled: March 24, 2005Date of Patent: November 18, 2008Assignee: Henkel KGaAInventor: Neil R. Wilson
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Patent number: 7452853Abstract: A warewashing detergent composition is provided according to the invention. The warewashing detergent composition includes a cleaning agent, an alkaline source, and a corrosion inhibitor. The cleaning agent comprises a detersive amount of a surfactant. The alkaline source is provided in an amount effective to provide a use composition having a pH of at least about 8. The corrosion inhibitor includes a source of aluminum ion and a source of zinc ion. The relative amounts of the source of zinc ion and the source of aluminum ion can be controlled to reduce visible filming when the warewashing detergent composition is used in the presence of hard water. Methods for using and manufacturing a warewashing detergent composition are provided.Type: GrantFiled: August 7, 2006Date of Patent: November 18, 2008Assignee: Ecolab Inc.Inventors: Kim R. Smith, Keith E. Olson, Howie Kestell, Michael J. Bartelme, Steven E. Lentsch, Victor F. Man, Burton M. Baum, Terence P. Everson
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Patent number: 7452854Abstract: This invention relates to thickened aqueous formulations containing cross-linked cationic polymers, novel homo- and copolymers their production and their use as thickeners for household formulations.Type: GrantFiled: May 27, 2003Date of Patent: November 18, 2008Assignee: Ciba Specialty Chemicals CorporationInventors: Michael Green, David Normington, Keith Graham, Gerhard Merkle, Emmanuel Martin
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Patent number: 7452855Abstract: A fragrance dispenser is provided according to the invention. A fragrance dispenser is provided for use in a dryer for dispensing a fragrance onto fabric or laundry dried in the dryer. The fragrance dispenser includes a mixture of a carrier component and a fragrance component so that the fragrance dispenser is provided in a solid form. The carrier component and the fragrance component are selected so that, when the fragrance dispenser is placed in a dryer and contacts fabric being dried during a drying cycle at a temperature of up to about 170° F., the carrier component does not flow onto the fabric and the fragrance component dispenses in an amount sufficient to impart a residual fragrance to the fabric. A method for dispensing fragrance onto fabric in a dryer is provided.Type: GrantFiled: April 14, 2005Date of Patent: November 18, 2008Assignee: Ecolab Inc.Inventors: Stephan M. Hubig, Jaclyn Joy Steep
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Patent number: 7452856Abstract: The present invention provides a novel peptide based on CAP11 as well as provides an antibacterial agent, an LPS-cell-binding inhibitor, and a drug such as a bacterial-infection-treating agent or an endotoxin-shock suppressant, each containing the peptide as an active ingredient. The peptide has the following amino acid sequence (SEQ ID NO: 1): X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03 (wherein X01 represents a cationic amino acid residue or a polar uncharged amino acid residue, X02 represents a non-polar amino acid residue, X03 represents a cationic amino acid residue, X04 represents a non-polar amino acid residue or a cationic amino acid residue, and X05 represents a non-polar amino acid residue or a polar uncharged amino acid residue). Each of the antibacterial agent, lipopolysaccharide-cell-binding inhibitor, and drug (e.g., bacterial-infection-treating agent or endotoxin-shock suppressant) contains the peptide as an active ingredient.Type: GrantFiled: March 29, 2005Date of Patent: November 18, 2008Assignees: Seikagaku Corporation, Juntendo UniversityInventors: Isao Nagaoka, Daiju Okuda, Shin Yomogida, Hiroshi Tamura
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Patent number: 7452857Abstract: Disclosed is a method of diagnosing irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, or Crohn's disease, which involves detecting the presence of small intestinal bacterial overgrowth (SIBO) in a human subject having at least one symptom associated with a suspected diagnosis of any of those diagnostic categories. Also disclosed is a method of treating these disorders, and other disorders caused by SIBO, that involves at least partially eradicating a SIBO condition in the human subject. The method includes administration of anti-microbial or probiotic agents, or normalizing intestinal motility by employing a prokinetic agent. The method improves symptoms, including hyperalgesia related to SIBO and disorders caused by SIBO.Type: GrantFiled: September 23, 2005Date of Patent: November 18, 2008Assignee: Cedars-Sinai Medical CenterInventors: Henry C. Lin, Mark Pimentel
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Patent number: 7452858Abstract: Methods for treating gestational diabetes which comprise administration of an effective amount of an exendin or an exendin agonist, alone or in conjunction with other compounds or compositions that lower blood glucose levels.Type: GrantFiled: November 17, 2005Date of Patent: November 18, 2008Assignee: Amylin Pharmaceuticals, Inc.Inventors: Richard A. Hiles, Kathryn S. Prickett
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Patent number: 7452859Abstract: The instant invention provides for proteins, polypeptides, nucleic acid sequences, constructs, expression vectors, host cells, pharmaceutical compositions of, and methods for using human placental bikunin, serine protease inhibitor domains, and fragments thereof.Type: GrantFiled: March 27, 2006Date of Patent: November 18, 2008Assignee: Aerovance, Inc.Inventors: Paul P. Tamburini, Gary Davis, Katherine A. Delaria, Christopher W. Marlor, Daniel K. Muller
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Patent number: 7452860Abstract: The invention relates to a formulation comprising a polypeptide selected from at least one of insulin, an insulin metabolite, an insulin analog, and an insulin derivative; at least one surfactant; optionally at least one preservative; and optionally at least one of an isotonicizing agent, a buffer or an excipient, wherein the formulation is free from or low in zinc. The invention also relates to the production of such insulin preparations and their use as pharmaceutical formulations.Type: GrantFiled: March 8, 2007Date of Patent: November 18, 2008Assignee: Sanofi-Aventis Deutschland GmbHInventor: Peter Boderke
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Patent number: 7452861Abstract: This invention is directed to methods of administering an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent having a substituent comprising at least about 8 carbon atoms. The invention is also directed to methods of using an echinocandin antifungal agent in combination with a specified glycopeptide antibacterial agent to treat fungal infections; and to compositions, kits and systems comprising an echinocandin antifungal agent and a specified glycopeptide antibacterial agent.Type: GrantFiled: July 21, 2004Date of Patent: November 18, 2008Assignee: Theravance, Inc.Inventor: Koné Kaniga
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Patent number: 7452862Abstract: Novel spatially-defined macrocyclic compounds containing specific conformational control elements are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target. In particular, compounds according to the invention are disclosed as agonists or antagonists of a mammalian motilin receptor and a mammalian ghrelin receptor.Type: GrantFiled: August 2, 2004Date of Patent: November 18, 2008Assignee: Tranzyme Pharma, Inc.Inventors: Pierre Deslongchamps, Yves Dory, Mark Peterson, Kamel Benakli, Eric Marsault, Luc Ouellet, Mahesh Ramaseshan, Martin Vézina, Daniel Fortin, Ruoxi Lan, Shigui Li, Gérald Villeneuve, Hamid Hoveyda, Sylvie Beaubien, Graeme L Fraser
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Patent number: 7452863Abstract: NGF variants which have trkC-binding activity and trkC-signal inducing activity are provided. The variants optionally have trkA or trkB binding and signal induction activity. The NGF variants of the present invention are useful in the treatment of neuronal disorders. Nucleic acids and expression vectors encoding the NGF variant neurotrophins are also provided.Type: GrantFiled: April 24, 1998Date of Patent: November 18, 2008Assignee: Genentech, Inc.Inventors: Leonard G. Presta, Roman Urfer, John W. Winslow
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Patent number: 7452864Abstract: Use of the antimicrobial cathelicidin peptide ll-37, N-terminal fragments of LL-37 or extended sequences of LL-37 having 1-3 amino acids in the C-terminal end, for stimulating proliferation of epithalial and stromal cells and thereby healing of wounds, such as chronic ulcers. The cytotoxic effect of LL-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising LL-37.Type: GrantFiled: January 28, 2004Date of Patent: November 18, 2008Assignee: Lipopeptide ABInventors: Mona Ståhle-Bäckdahl, Johan Heilborn, Anders Carlsson, Conny Bogentoft
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Patent number: 7452865Abstract: There is provided a novel series of synthetic antagonistic analogs of hGH-RH(1-29)NH2. These analogs inhibit the activity of endogenous hGH-RH on the pituitary GH-RH receptors, and therefore prevent the release of growth hormone. The analogs also inhibit the proliferation of human cancers through a direct effect on the cancer cells. The higher inhibitory potencies of the new analogs, as compared to previously described ones, results from replacement of various amino acids.Type: GrantFiled: July 26, 2004Date of Patent: November 18, 2008Assignees: The Administrare's of the Tulane Educational Fund, United States of America by Dept of Veterans AffairsInventors: Andrew V. Schally, Jozsef Varga, Marta Zarandi, Ren Zhi Cai
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Patent number: 7452866Abstract: The present invention relates to methods of inhibiting angiogenesis associated with a disease or disorder with peptides homologous to amino acid residues 130-137 or 132-139 of human troponin subunit I.Type: GrantFiled: January 5, 2006Date of Patent: November 18, 2008Assignees: Children's Medical Center Corporation, Alseres Pharmaceuticals, Inc.Inventors: Richard M. Thorn, Mark A. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
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Patent number: 7452867Abstract: This invention relates to the use of ADNF polypeptides in the treatment of neurotoxicity induced by chemical agents or by disease processes. The ADNF polypeptides include ADNF I and ADNF III (also referred to as ADNP) polypeptides, analogs, subsequences such as NAP and SAL, and D-amino acid versions (either wholly D-amino acid peptides or mixed D- and L-amino acid peptides), and combinations thereof which contain their respective active core sites.Type: GrantFiled: March 23, 2006Date of Patent: November 18, 2008Assignee: Ramot at Tel-Aviv University, Ltd.Inventors: Illana Gozes, James Miller
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Patent number: 7452868Abstract: A formulation of octreotide or pharmaceutically acceptable salts thereof, which provides controlled release of a therapeutically effective amount of octreotide for a period of at least about two months. Methods of treating acromegaly, decreasing growth hormone, decreasing IGF-1, and treating conditions associated with carcinoid tumors and VIPomas by administering a controlled release formulation of octreotide are provided herein.Type: GrantFiled: March 10, 2006Date of Patent: November 18, 2008Assignee: Indevus Pharmaceuticals, Inc.Inventors: Petr Kuzma, Stephanie Decker
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Patent number: 7452869Abstract: Methods and compositions for modulating necrosis and for treating neurological and cardiovascular diseases are described. The inventors have shown that BNIP3 is involved in cell necrosis and cell death involved in cardiovascular and neurological diseases.Type: GrantFiled: November 8, 2002Date of Patent: November 18, 2008Assignee: University of ManitobaInventors: Faye Hellner, legal representative, Jonathan D. Geiger, Lorrie A. Kirshenbaum, Arnold H. Greenberg
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Patent number: 7452870Abstract: The present invention provides a P2Y12 receptor antagonist compound-eluting stent, wherein the stent is coated with one or more P2Y12 receptor antagonist compounds or a pharmaceutically acceptable salt, solvate, or hydrate thereof. When the stent is placed in a narrowed or damaged arterial vessel, a therapeutically effective amount of the P2Y12 receptor antagonist compound is eluted continuously from the stent to the local environment of the stent. The P2Y12 receptor antagonist compound-eluting stents are useful in preventing thrombosis and restenosis, and are effective in inhibiting the contraction of vascular smooth muscle cells, inhibiting cell proliferation, and reducing inflammation.Type: GrantFiled: November 4, 2005Date of Patent: November 18, 2008Assignee: Inspire Pharmaceuticals, Inc.Inventors: José L. Boyer, James G. Douglass, III, Sammy R. Shaver
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Patent number: 7452871Abstract: A modified alginate and/or modified pectin composition and method for preventing and/or treating diseases and/or conditions caused by circulating agents such as poisonous heavy metals, environmental toxins, calcium and cholesterol, is provided. The composition includes a modified alginate having a molecular weight of no more than 40,000 daltons and/or a modified pectin having a molecular weight of no more than 40,000 daltons. The method involves orally or intravenously administering the modified alginate and/or modified pectin composition, alone or with excipient.Type: GrantFiled: November 28, 2005Date of Patent: November 18, 2008Assignee: EcoNugenics, Inc.Inventor: Isaac Eliaz
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Patent number: 7452872Abstract: A method of increasing the bioavailability of balsalazide by administration of an oral dosage form with food is provided, as well as an article of manufacture comprising an oral dosage form of balsalazide in a suitable container and associated with printed labeling which describes the increased bioavailability of the medication in the container when taken with food.Type: GrantFiled: August 8, 2007Date of Patent: November 18, 2008Assignee: Salix Pharmaceuticals, Inc.Inventor: Lorin Johnson