Abstract: These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

Abstract: A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.

Abstract: A dedicated distal protection guidewire having proximal and distal stops disposed about an elongated core wire is disclosed. A guidewire in accordance with the present invention includes an elongated core wire having a relatively stiff proximal section and a relatively flexible distal section, a distal stop disposed about a portion of the elongated core wire, and a proximal stop disposed about a portion of the elongated core wire proximal the distal stop. The distal stop may be formed from an enlarged outer diameter portion on the elongated core wire, or may be formed from an object disposed about and secured to a portion of the elongated core wire. The proximal stop may include an O-ring disposed within a recessed surface on the elongated core wire, or an annular ring having several circumferentially disposed notches.

Abstract: Device for the time-based analysis of the agitation of a bedridden patient includes elements (4) for acquiring the patient's shouts and elements (5) for acquiring the patient's movements, the acquisition elements being connected to storage elements (9) suitable for storing the acquired data accompanied by a time stamping of the latter, the storage elements being connected to analysis and presentation elements (10) suitable for providing care staff with a representation of the frequency and duration of the patient's shouts and movements which are representative of the patient's agitation over a determined time span, characterized in that the elements for acquiring shouts include a bandpass filter (6) suitable for isolating the shouts from speech and ambient noise.

Abstract: Multifunction equipment installed in a room is provided. The multifunction equipment has main body and movable device that moves to implement plural functions, thereby allowing the multifunction equipment to be used as plural functional devices. The movable device is connected to the main body. The multifunction equipment also has assisting device that assists a use of the multifunction equipment as a desired functional device when the movable device moves to allow the multifunction equipment to be used as the desired functional device.

Abstract: The present invention is a portable integrated sound, physioacoustic, and colored light apparatus. This is a self-contained electrically powered device designed to stimulate and facilitate the human body's innate self-healing mechanisms. The active components are housed in a portable pyramidal-shaped lower enclosure (100) with a single recessed panel (102) on one side of the unit containing a user interface for controlling the pitch and tonal quality of the generated sound and physioacoustic frequencies. The unit also contains specified colored light elements situated under a quartz crystal pyramid capstone (108) which react with the sound frequencies by increasing and decreasing in intensity. The user or therapist has the capability to access the electronically generated sound source to achieve a wide variety of tonal sound and vibrational components, as well as the ability to select the desired colored light therapy component.

Abstract: A compression wrap for application to body members having a top layer and a bottom layer with an inflatable bladder of smaller dimension positioned therebetween, an interiorly positioned pocket for insertion of a gel pack and a hand-bulb for increasing the pressure within the bladder and thereby applying pressure to the gel pack. To remove the compression wrap, the hand bulb is mounted in a reverse direction and pumped to deflate the bladder.

Abstract: An orthotic brace includes a proximal support section pivotally connected to a distal support section, and each having a medial frame and a lateral frame connected to width adjustment plates. At least one angle adjusting component provided in the lateral or medial frames allows angular adjustment of the brace. The width adjustment plates include lateral and medial slots through which fixing members pass to engage the respective frame portions. This permits the space between the lateral frame and the medial frame to be adjusted according to the size of the wearer's body part. Proximal and distal shells are adjustably positioned on the width adjustment plates via a series of positioning holes axially arranged along the shells which selectively engage a fixing member passing through a positioning slot on the width adjustment plates. This allows for the shells to be both axially adjusted and positioned along the width of the brace.

Abstract: A patella stabilization system having a unitary patella stabilizer sleeve extending at both ends into a plurality of straps for securing the patella stabilizer sleeve around a knee region and an upper inner strap extending from a first upper end of the patella stabilizer sleeve and an upper outer strap extending from a second upper end of the patella stabilizer sleeve, the upper outer strap comprising a fastener at a distal end of the upper outer strap. The system further includes a lower inner strap extending from a first lower end of the patella stabilizer sleeve and a lower outer strap extending from a second lower end of the patella stabilizer sleeve, the lower outer strap comprising a fastener at a distal end of the lower outer strap, a plurality of slots around a patella opening, and a buttress comprising a plurality of straps adapted to be adjustably positioned on an inside surface of the patella stabilizer band around a location on a circumferential edge of the patella opening.

Abstract: An elongate flexible strap is adapted to be wrapped about a wearer's leg and pelvic region. The strap applies a torque to the leg, rotating the leg into a desired degree of external rotation. In a leg having an improperly aligned patella, it is believed that the external rotation improves lower extremity mechanics by aligning the patella within the trochlear groove.

Abstract: A lightweight, flexible, aerating, compressive, thermal material. Perforations allow the treatment area to aerate. Thermal capacity of the invention allows for hot or cold treatment in a manner that compressively supports the object undergoing thermal treatment while maintaining maximum mobility. The material is made from an elastomer such as polyurethane with the addition of silicon and vegetable oil. Resin is used to color the product.

Abstract: A blood purification apparatus includes a blood circuit, a blood purifying device, a driving device, an air bubble detection device, and a connection condition evaluation device. The blood circuit is provided with arterial and venous blood circuits, to which needles are attached at ends thereof. The blood purifying device is connected between the arterial and venous circuits. In a blood purifying treatment after a priming operation, the driving device drives the blood in the arterial blood circuit in a forward direction, and drives the blood in the venous blood circuit in a reverse direction. The air bubble detection device detects air bubbles in a liquid flowing in the arterial and venous blood circuits. The connection condition evaluation device evaluates connection conditions of the needles to the ends of the arterial and venous blood circuits based on the detection by the air bubble detection device.

Abstract: Apparatuses, devices, systems and methods for detecting access disconnection are provided. In one embodiment, a medical fluid system includes (i) a medical fluid machine and (ii) a device operable with the medical fluid machine, the device configured to provide electrical contact with a medical fluid, the device including (a) a tube used during dialysis therapy through which the medical fluid can flow, and (b) a conductive element configured to self-sealingly pierce the tube, the conductive element having a first portion exposed to the medical fluid and a second portion external to the tube.

Abstract: A catheter assembly is provided with a flexible tubular body having two lumens. A solid slidable member with a sharp distal end is disposed within one of the lumens. The slidable member is capable of sliding within the lumen of the tubular body between an exposed position in which the sharp distal end of the slidable member protrudes from the distal end of the tubular body and a shielded position in which the distal end of the slidable member is within the tubular body. One advantage is that the sharp distal end of the slidable member may be withdrawn into the tubular body in order to shield a patient from unintentional cutting or irritation from the sharp distal end of the slidable member.

Abstract: An extracorporeal circuit, which makes it possible to efficiently collect priming solution by displacing the priming solution with blood after the priming solution is fed to the extracorporeal circuit to prime the extracorporeal circuit, includes a circuit body including first and second tubes, a feed bag that feeds the priming solution, a blood reservoir in which a liquid is temporarily stored, a third tube that branches out from the middle of the first tube, and a collection bag which communicates with the third tube and into which the priming solution is collected through the third tube. After the priming solution is fed from the feed bag to prime at least a housing, when the priming solution in the housing is displaced by blood, the priming solution in the housing is transferred and collected in the collection bag due to a height difference between the liquid level and the collection bag.

Abstract: An irrigation and aspiration system is disclosed. The system can be configured to aspirate and irrigate alone, sequentially or concurrently. The system can be configured to aspirate and irrigate the nasal cavity. The system can be manually controlled. The system can have removable and easily cleanable reservoirs for aspirant and irrigant.

Abstract: Some embodiments an infusion pump system can be used to determine a user's total insulin load (TIL) that provides an accurate indication of the insulin previously delivered to the user's body which has not yet acted. In particular embodiments, the TIL can account for both the bolus deliveries and the basal deliveries that have occurred over a period of time. Such information may be useful, for example, when the infusion pump is operated in conjunction with a continuous glucose monitoring device.

Abstract: The invention relates to a disposable injector with a housing, an injector-side, first cylinder-piston unit—at least intermittently fillable—arranged thereon and an upstream detachable container adapter, wherein the container adapter bears a likewise at least intermittently fillable second cylinder-piston unit. A solvent is stored in the first cylinder-piston unit. In the second cylinder-piston unit there is a freeze-dried active pharmaceutical ingredient. Immediately before use of the disposable injector the solvent is conveyed to the second cylinder-piston unit to the active pharmaceutical ingredient, where a solution forms. This solution is transfer-pumped into the first cylinder-piston unit to then be administered. The present invention develops a disposable injector which stores a liquid and an active ingredient in each case separately and sterilely and provides a space in which the active ingredient is dissolved for application in the liquid or mixed with the liquid.

Abstract: A container closure delivery system that is suitable for lyophilized pharmaceutical injectable powder products is disclosed. The system comprises storage stable powder formulations and a container closure assembly design wherein the formulation can be filled and lyophilized with a standard fill finish equipment, and the formulations and lyophilization processes are optimized to produce a powder that readily dissolves upon contact with a diluent, thereby facilitating the direct injection of the lyophilized product without the need for a separate reconstitution/mixing/priming step.

Abstract: An improved steerable catheter with in-plane deflection comprises a catheter body having proximal and distal ends and a lumen extending therethrough and a tip section at the distal end of the catheter body. The tip section comprises a flexible plastic tubing having a pair of diametrically-opposed lumens extending therethrough. The catheter also provides two puller wires manipulated through a control handle at the proximal end of the catheter body. Each puller wire extends through one of the pair of lumens in the tip section and through the lumen of the catheter body and is anchored to the control handle at its proximal end and anchored to the tip section at its distal end. The deflection mechanism is configured to generally define a plane along which deflection most readily occurs and an edge along which deflection is most readily avoided.

Abstract: Apparatus with a pneumatic or hydraulic or mechanical therapeutic catheter. The therapy energy required to treat internal vessels of the patient is transferred by the same fluid or the same elements from the proximal end section to the distal end section of the catheter that transfer information from the distal end section to the proximal end section of the catheter. The information provides understanding of the state of the vessel and how the therapy fluid of the therapy element of the catheter acts on the vessel.

Abstract: An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a blood vessel, includes providing an elongate member having proximal and distal ends, a lumen therebetween, the distal end having a braided sheath expandable between a reduced and expanded diameter, and a fluid-tight covering. The elongate member is advanced into a blood vessel that supplies blood to the heart. The braided sheath is expanded to engage the endoluminal surface of the blood vessel and stop antegrade flow.

Abstract: A suction regulator for controlling a level of negative pressure in a system in which compensatory clean airflow is used to isolate a control device for regulating suction delivered to a patient is disclosed. The regulator comprises an inlet; an outlet; a controller for controlling the suction delivered to the inlet; and a barrier for isolating the controller from the inlet.

Abstract: An angiographic injector system includes a manifold and valve which selectively connects either a syringe pump or a low pressure system to a catheter which is inserted into a patient. The valve is normally biased to a state which connects the low pressure system to the catheter for pressure monitoring, saline flushing, or aspirating functions. When an injection is to be made, the valve automatically switches so that the low pressure system is disconnected and not exposed to high pressure, while the syringe pump is connected through the manifold to the catheter.

Abstract: A system for the metering and delivery of small discrete volumes of liquid is comprised of a small or minimal number of inexpensive components. One such component is a movable member, such as a miniature precision reciprocating displacement pump head, which is driven by an actuator that comprises a shape memory alloy material. The operating mechanism of the system is of little or minimal complexity. The system facilitates the precise metering and delivery of the small discrete volumes of liquid. Potential applications for the system include subcutaneous, long-term, automated drug delivery, for example, the delivery of insulin to a person with diabetes. In such an application, the small, simple and inexpensive nature of the invention would allow for its use as both a portable and a disposable system.

Abstract: A fluid delivery device is provided for delivering fluid to a target site such as an intervertebral disc during discography. The fluid delivery device includes pressure and volume sensors to determine the pressure and the volume of the fluid delivered to the intervertebral disc. The fluid delivery device is hand-held during use and includes a syringe assembly having a plunger with threads that enables controlled discharge of the fluid from the fluid delivery device by rotating the plunger in a housing of the fluid delivery device. The fluid delivery device may also include a communication module to wirelessly transfer data to an external device outside of a sterile field, while the fluid delivery device is in the sterile field. The fluid delivery device may also include a physiological sensor to monitor involuntary pain responses based on changing physiological parameters such as increases in body temperature or blood pressure.

Abstract: A device suitable for removing material from a living being is provided, featuring an infusate pump, and an aspiration pump, both powered by a motor. The aspiration pump and infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature.

Abstract: The present invention is directed to metering devices, systems, and methods that mitigate differential thermal expansion/contraction for the efficient, accurate, and reproducible metered delivery of fluids. The present invention allows the net fluid volume and a plunger location within a fluid dispensing container to automatically adjust under the influence of differential thermal expansion/contraction between the fluid and the fluid dispensing container that the fluid is contained within. Further, the present invention allows the metering system drive to sense the adjusted plunger location and allows the metering system drive to re-zero itself to produce an accurate volumetric delivery of fluid from the fluid dispensing container. The metering system includes means for controlling the travel of the metering system drive, and hence the travel of the plunger into the fluid dispensing container, for delivering accurate/precise amounts of the fluid from the fluid dispensing container.

Abstract: An apparatus and method for insertion of medical devices is disclosed. One embodiment includes an access tube with a retention portion disposed at a distal end. The retention portion is reconfigurable between first and second configurations of reduced and increased lateral extent. A trocar can be movably disposed within the access tube, which can be movably disposed within an overtube. One method of the invention includes inserting the trocar and access tube through a patient's body wall where the retention portion is configured from a reduced to an increased lateral extent. An overtube can be inserted around the access tube through the body wall where the retention portion can be received through a slot defined by the overtube. The retention portion can be returned to reduced lateral extent. The access tube can be removed and the medical device can be inserted within the overtube.

Abstract: Disclosed is a urinary catheter immobilizer for immobilizing movement of a urinary catheter in a human body. The urinary catheter immobilizer comprises a funnel-shaped member and a body member configured to be received over the funnel-shaped member. The funnel-shaped member has a first end portion and a second end portion. The first end portion is capable of being received over a urinary meatus of the human body. The body member is configured to be received over the second end portion of the funnel-shaped member and capable of removably attaching to an external portion of the urinary catheter. The body member comprises a torus-shaped structure and at least one elongated tubular structure. The torus-shaped structure comprises at least one channel. The at least one channel is capable of receiving the at least one elongated tubular structure for looping around the torus-shaped structure for immobilizing the urinary catheter.

Abstract: Devices and methods for simultaneous injection or delivery of two or more substances from separate syringes. The syringes are loaded into a device that has a handle and a screw driven mechanism for simultaneously depressing the plungers of the syringes. The user grasps the handle and positions the device. Thereafter, the screw mechanism is used to simultaneously advance the plungers of the syringes thereby simultaneously expelling the substances from the syringes.

Abstract: An intravenous catheter introducer assembly having a safety feature to prevent accidental needle sticks. The introducer assembly includes a needle assembly having a groove disposed on its outer surface. The introducer includes a protector made of a hollow member having an open distal end and an inwardly disposed resilient flange or a clip disposed thereon. The protector is coaxially slidably disposed around the needle with the flange abutting the outer surface of the needle and adapted to engage the groove when a catheter assembly is removed from the needle.

Abstract: A pressure actuated flow control valve for an infusion catheter permits gravity flow of a liquid through the catheter and into a patient while resisting back flow of blood from the patient and into the catheter. The valve has a hemispherical body with an outstanding circumferential flange and a normally closed, diametric slit. The slit is longer on the convex outer surface than on the concave inner surface. Dome thickness diminishes in the area adjacent the slit, reducing total apical deflection upon collapse of the slit toward the concave surface. An inner orthogonal rib biases the slit closed. Upon application of a predetermined pressure, the slit opens toward the concave surface to permit forward fluid flow. At lower pressures, the slit closes to check fluid flow. Greater reverse pressure is required to collapse the slit toward the concave surface to permit reverse fluid flow.

Abstract: An access port for subcutaneous implantation is disclosed. Such an access port may comprise a body for capturing a septum for repeatedly inserting a needle therethrough into a cavity defined within the body. Further, the access port may include at least one feature structured and configured for identification of the access port subsequent to subcutaneous implantation. Methods of identifying a subcutaneously implanted access port are also disclosed. For example, a subcutaneously implanted access port may be provided and at least one feature of the subcutaneously implanted access port may be perceived. Further, the subcutaneously implanted access port may be identified in response to perceiving the at least one feature.

Abstract: Embodiments of the invention provide a stretchable sleeve having a medicinal section that can be loaded with a medicinal composition and a perforated section comprising a plurality of openings, wherein the medicinal section and the perforated section overlap, and wherein the sleeve is sized so that the interior surface of the medicinal section comfortably fits a body portion and the medicinal section contacts the body portion at the site of pain. Embodiments of the invention also provide methods for preparing a sleeve by applying a medicinal composition to the inner surface of the medicinal section through the openings at the perforated section. Embodiments of the invention also provide methods for relieving pain in a body portion by pulling the sleeve in an outside-out configuration straight up a body portion without having to roll and flip its exterior surface outside.

Abstract: The subject invention provides novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation. In one embodiment the subject invention provides a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.

Abstract: A pant-shaped garment includes an outer panty having a length direction and a transverse direction and having a rear portion, a front portion, and a crotch portion. The garment includes a waist opening with a waist edge extending in the transverse direction and two leg openings each being bordered by a leg edge having a front part of the leg edge being located generally on the front portion and a rear part of the leg edge being located generally on the rear portion and on the crotch portion. The rear and front portions are mutually connected in two side joins running in the length direction from the waist opening to each leg opening. The front and rear portions of the outer panty substantially comprise an elastically extensible material. The rear part of each leg edge is curve-shaped and exhibits a concave curved segment located mainly on the rear portion.

Abstract: Disposable hygiene pants with a front portion (2), a rear portion (3) and a crotch portion (4) provided with two leg openings (5, 6), the longitudinal edge portions (21, 22) of the front portion being connected by longitudinal weld seams (7, 8) to the longitudinal edge portions (31, 32) of the rear portion (3) in order to form a waist opening (9) and two leg openings (5, 6) in the crotch portion, which leg openings are outwardly delimited in the transverse direction by the inner end portions of the weld seams as seen in the longitudinal direction of the hygiene pants. The hygiene pants have an outer cover (10) and comprise an absorption unit (11). The cover is preferably made of an elastic laminate. The weld seams (7, 8) are each reinforced by at least one reinforcing strip (15, 16) containing thermoplastic fibers and have a tensile strength, in a direction transverse to the weld seam, in excess of 5 N/25.4 mm at least in the portions reinforced with said nonwoven strip (15, 16).

Abstract: The invention is directed to an absorbent article, which is preferably a sanitary napkin or a pantiliner, comprising: a body contacting layer; a garment contacting layer; and an absorbent core disposed between the body contacting layer and the garment contacting layer. The absorbent core has a core edge. The core edge defines a core region within the core edge and an outer region outside the core region. The body contacting layer and the garment contacting layer extend outward into the outer region and joined together in the outer region. In one aspect of the invention, the garment contacting layer has a graphic printed on the body facing surface at least in a portion of the outer region. In another aspect of the invention, the body contacting layer has a graphic printed on the garment facing surface at least in a portion of the outer region. The body contacting layer has a first light transmittance so that the graphic can be seen through the body contacting layer in the outer region.

Abstract: An array of disposable absorbent articles comprising a sequence of graphic designs corresponding to a wearer's stage of development. For a disposable diaper, the array of disposable absorbent article graphic designs may comprise a first absorbent article graphic design for newborns and infants, a second absorbent article graphic design for toddlers, and a third absorbent article graphic design for older wearers, and other absorbent article graphic designs.

Abstract: A sanitary napkin includes a liquid-permeable topsheet, a backsheet, and a liquid-absorbent layer disposed between the topsheet and the backsheet. The liquid-absorbent layer has a vagina-facing region on a longitudinal centerline of the sanitary napkin and side regions on both sides of the vagina-facing region. The liquid-absorbent layer has a greater thickness and a greater bending stiffness in the vagina-facing region than in the side regions to provide hinge lines along boundaries between the vagina-facing region and the side regions.

Abstract: A pain management system for the infusion of drug to a wound site includes a pump connected to medical tubing which is connected to an improved infusion catheter for providing uniform delivery of fluid throughout an anatomical region. One method by which the infusion catheter is advanced to the wound site includes a guide needle that is placed within an introducer tubing. The needle is pierced through the patient's skin, after which the guide needle is withdrawn and discarded, leaving the introducer tubing in place partially under the patient's skin. The infusion catheter is then threaded through the introducer tubing and advanced to the wound site. The introducer tubing is then withdrawn and the infusion catheter remains in place to provide drug to the wound site. The introducer tubing is preferably peeled off of the infusion catheter and discarded.

Abstract: The invention relates to a device (100) for treating wounds of the human or animal body using a vacuum and having a gas-tight wound-covering element (4), which, when placed in contact with the body of the patient, forms a wound space (10) between the respective wound and the wound-covering element, at least one connecting site (5.1; 5.2), which is in contact with the wound space (10), an absorption body (2), which is a layer, enclosed in an envelope, of a textile section, interspersed with super-absorbing particles, the envelope being permeable to liquids and having pores, the size of which does not exceed that of the super-absorbing particles.

Abstract: A cryosurgical system adapted for treatment of fibroadenomas within the breast of a patient. The system includes cryoprobes and a control system which operates the cryoprobes to accomplish freezing in two stages, including a high power freeze and a low power freeze.

Abstract: A method of applying ablation energy to achieve transmurality including applying ablation energy at a starting power to a tissue site and monitoring the impedance of the tissue site. The power applied to the tissue site can be increased in response to detection of a power plateau or application of a first power for a minimum time according to some embodiments. A power applied to the tissue site can be reduced in response to an increase in impedance according to some embodiments. Transmurality can be indicated in response to a transmurality plateau following a rise in impedance according to some embodiments.

Abstract: Apparatus for treating abnormal mucosa in an alimentary tract are provided. The apparatus include an ablation structure configured to be removably coupled to an endoscope and a deflection mechanism adapted to move the ablation structure with respect to the endoscope and toward a tissue surface.

Abstract: A tissue ablation device assembly ablates a region of tissue in a body of a patient. The tissue ablation device assembly comprises an elongated body having a proximal end portion and a distal end portion. A tubular porous membrane having a porous wall with an inner surface that defines an inner space is located along the distal end portion of the elongated body. An ablation element is disposed over the porous membrane, with the ablation element having a fixed position with respect to the porous membrane. A fluid passageway extending through the elongated body and communicates with the inner space. The fluid passageway is adapted to be fluidly coupled to a pressurizeable fluid source for delivering a volume of pressurized fluid from the fluid source to the inner space. The porous membrane allows at least a substantial portion of the volume of pressurized fluid to pass through the porous wall for enhancing ablative coupling between the electrode and the region of tissue.

Abstract: A medical probe assembly, tissue treatment system, and method are provided for ablating tissue. The probe assembly comprises an elongated member and electrode elements mechanically coupled to the distal end of the elongated member. The electrode elements are configurable as two bipolar electrode pairs with a common electrode element. At least one of the electrode elements comprises a plurality of electrodes (such as, e.g., needle electrodes) radially extendable from the elongated member. An ablation source, such as a radio frequency source, can be connected to the probe assembly in order to convey ablation energy to the electrode pairs, either simultaneously or sequentially.

Abstract: The present inventions provide assemblies, probes, and methods for creating circumferential lesions in tissue, e.g., the tissue within or around the ostium of a vessel. An ablation probe with an ablative structure can be placed in contact within or around the ostium of the vessel. A diagnostic probe can be introduced through a lumen within the ablation probe and inserted into the vessel. The energy can be provided to the ablative structure to create a circumferential lesion within or around the ostium of the vessel, and the diagnostic structure can be used to diagnose the tissue to determine whether the circumferential lesion can be properly created.

Abstract: A tissue ablation device includes an array of elongate electrodes configured to be deployed in tissue, wherein the deployed electrode array defines a tissue ablation region, an inflatable balloon configured to be deployed in tissue, and a coupler securing the balloon relative to the one or more elongate electrodes, wherein the balloon, when inflated, is configured to apply a force to tissue located in the tissue ablation region. An ablation device includes a first array of electrodes, a second array of electrodes, a first inflatable balloon, and a coupler securing the first balloon relative to the first and second electrode arrays. A method of ablating tissue includes positioning an array of elongate electrodes and an inflatable balloon proximate tissue to be ablated, inflating the balloon to compress a tissue region located between the balloon and the electrode array, and energizing the electrode array to ablate the tissue region.