Patents Issued in August 28, 2014
  • METHODS
    Publication number: 20140242097
    Abstract: A method for promoting entry of an agent (introduced agent) into a cell, the method comprising the step of complexing the introduced agent in the presence of an entry-promoting agent and then exposing to cells, wherein the entry-promoting agent comprises a linear and/or branched or cyclic polymonoguanide/polyguanidine, polybiguanide, analogue or derivative thereof according to the following Formula 1a & b. The method also provides a means for formation of nanoparticles formed between the entry promoting agent and the introduced agent.
    Type: Application
    Filed: October 11, 2012
    Publication date: August 28, 2014
    Applicant: THE ROYAL VETERINARY COLLEGE
    Inventors: Liam Good, Kantaraja Chindera, Valentina Gburcik
  • DRUG DISPENSING AND DOSING METHOD AND DEVICE
    Publication number: 20140242098
    Abstract: Flexible film or strip dosing device and method for various therapeutic applications are disclosed. The device includes at least one film or strip and a packaging container for the film or strip. The film or strip normally include a polymer base with or without a therapeutic agent admixed with the polymer base. The film or strip is printed with doses, marks or calibrated lines to indicate different length of the film and therefore the different doses of the therapeutic agents. The packaging container or dispenser can have marks or calibrated lines similar to a ruler which measures the length of film and therefore the different doses of therapeutic agents. The packaging container may have a built-in cutter to conveniently cut the film or strips as needed for flexible dosing of therapeutic agents.
    Type: Application
    Filed: February 24, 2014
    Publication date: August 28, 2014
    Applicant: MONMOUTH UNIVERSITY
    Inventor: Xudong Yuan
  • COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES
    Publication number: 20140242099
    Abstract: The invention relates to certain compounds or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
    Type: Application
    Filed: October 26, 2012
    Publication date: August 28, 2014
    Inventors: Shoujun Chen, Junyi Zhang, Jun Jiang, Teresa Kowalczyk-Przewloka, Zhiqiang Xia, Shijie Zhang
  • METHODS AND COMPOSITIONS FOR THE GENERATION AND USE OF CONFORMATION-SPECIFIC ANTIBODIES
    Publication number: 20140242100
    Abstract: The present invention features methods and compositions for the generation of conformation-specific antibodies.
    Type: Application
    Filed: April 27, 2012
    Publication date: August 28, 2014
    Applicant: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Kun Ping Lu, Xiao Zhen Zhou
  • PD-L1 BASED IMMUNOTHERAPY
    Publication number: 20140242101
    Abstract: The present invention relates to the field of prophylaxis and therapy of clinical conditions including cancer, autoimmune diseases and infectious diseases. In particular there is provided vaccine compositions comprising PD-L1 or peptide fragments thereof that are capable of eliciting immune responses useful in treatment of cancer, autoimmune diseases or infectious diseases.
    Type: Application
    Filed: October 17, 2012
    Publication date: August 28, 2014
    Applicant: HERLEV HOSPITAL
    Inventor: Mads Hald Andersen
  • INFLUENZA HEMAGGLUTININ AND NEURAMINIDASE VARIANTS
    Publication number: 20140242102
    Abstract: Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin and neuraminidase variants are provided.
    Type: Application
    Filed: January 15, 2014
    Publication date: August 28, 2014
    Applicant: MEDIMMUNE, LLC
    Inventors: Chin-Fen YANG, George KEMBLE, Chongguang LIU
  • COMPOSITION
    Publication number: 20140242103
    Abstract: The present invention provides a modified influenza virus wherein the RNA of the haemagglutinin gene has been modified such that the haemagglutinin signal sequence is not expressed and the virus produces a haemagglutinin protein that lacks a functional signal sequence. The invention further provides composition comprising the modified virus and uses of the modified virus.
    Type: Application
    Filed: September 21, 2012
    Publication date: August 28, 2014
    Applicant: ISIS INNOVATION, LTD.
    Inventor: Alain Townsend
  • SELF-ASSEMBLING PEPTIDE NANOPARTICLES AS VACCINES AGAINST INFECTION WITH NOROVIRUS
    Publication number: 20140242104
    Abstract: Self-assembling peptide nanoparticles (SAPN) incorporating T-cell epitopes and displaying the P domain of the norovirus protein VP1 are described. The nanoparticles of the invention consist of aggregates of a continuous peptide chain comprising two coiled coil oligomerization domains connected by a linker segment wherein one or both oligomerization domains incorporate T-cell epitopes within their peptide sequence. These nanoparticles are useful as vaccines and adjuvants for the prevention and treatment of norovirus infections.
    Type: Application
    Filed: October 5, 2012
    Publication date: August 28, 2014
    Applicant: ALPHA-O PEPTIDES AG
    Inventors: Peter Burkhard, Caroline Kulangara
  • VACCINES FOR CHLAMYDIA
    Publication number: 20140242105
    Abstract: The present invention relates to means and methods to protect against disease caused by bacteria belonging to the genus Chlamydia. In particular, the present invention relates to isolated B- and T-cell epitopes derived from the major outer membrane protein of Chlamydia psittaci which can be used against an infection with a species of the genus Chlamydia. More in particular, the invention provides a vaccine which can be used against chlamydiosis caused by Chlamydia psittaci in birds and man. In addition, the invention relates to a diagnostic method to diagnose the latter infections.
    Type: Application
    Filed: June 15, 2012
    Publication date: August 28, 2014
    Applicant: UNIVERSITEIT GENT
    Inventor: Daisy Vanrompay
  • STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS
    Publication number: 20140242106
    Abstract: The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
    Type: Application
    Filed: April 28, 2014
    Publication date: August 28, 2014
    Applicant: NOVARTIS AG
    Inventors: Vega MASIGNANI, Mariarosa MORA, Maria SCARSELLI
  • Direct Protein Delivery with Engineered Microvesicles
    Publication number: 20140242107
    Abstract: The present invention relates to direct protein delivery with engineered micro vesicles.
    Type: Application
    Filed: February 25, 2014
    Publication date: August 28, 2014
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Philippe Mangeot, Vincent Lotteau
  • Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists
    Publication number: 20140242108
    Abstract: A conjugated compound of Formula I: Q-Z—R4 wherein Q is a TLR7 and/or TLR8 agonist and Z—R4 is a TLR2 agonist, the conjugated compound being chosen among compounds of Formula II:
    Type: Application
    Filed: February 22, 2013
    Publication date: August 28, 2014
    Applicant: CAYLA
    Inventors: Thierry LIOUX, Daniel DROCOURT, Fabienne VERNEJOUL, Gerard TIRABY, Eric PEROUZEL
  • METHOD FOR CULTIVATING ALGA AND METHOD FOR PRODUCING ALGINIC ACID-CONTAINING COMPOSITION
    Publication number: 20140242109
    Abstract: The objective of the present invention is to provide a method for cultivating an alga having ability to produce alginic acid industrially and effectively and a method for producing an alginic acid-containing composition industrially advantageously. The method for cultivating an alga according to the present invention is characterized in comprising the step of cultivating the alga heterotrophically, wherein the alga belongs to the genus Parachlorella and has ability to produce alginic acid.
    Type: Application
    Filed: September 6, 2012
    Publication date: August 28, 2014
    Applicant: KANEKA CORPORATION
    Inventors: Noriyuki Kizaki, Takeshi Furuta, Taku Mouri, Naoaki Taoka
  • Dose, localization, and formulation of botulinum toxins in skin and muscle
    Publication number: 20140242110
    Abstract: Formulations of and dosing protocols for the administration of botulinum toxin that maximize efficacy and specificity while minimizing the likelihood of overdosing and undesirable side effects of treatment. The formulations include positively charged carriers, such as cationic peptides, which otherwise have no inherent botulinum-toxin-like activity. The dosing regimen is based on the pattern, quantity, and location of neuromuscular junctions in the target tissue. Because the number of neuromuscular junctions in a target tissue remains generally stable throughout life and because the pharmacological effect of botulinum toxin is localized at the neuromuscular junction, dosing efficacy is unaffected by muscle mass, age of the patient, or body weight.
    Type: Application
    Filed: February 28, 2013
    Publication date: August 28, 2014
    Inventor: L. Andrew Koman
  • Engineered Bacteria for Oral Delivery of Glucoregulatory Proteins
    Publication number: 20140242111
    Abstract: Disclosed is an oral delivery system that overcomes major barriers encountered in the gastrointestinal tract, particularly rapid proteolytic degradation and low intestinal permeability. Provided is a method for oral delivery of an engineered microorganism to a mammal where the microorganism produces a macromolecule having a desired bioavailability outcome.
    Type: Application
    Filed: March 8, 2012
    Publication date: August 28, 2014
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Casim Ali Sarkar, Ting Wun Ng
  • NOVEL VACCINE
    Publication number: 20140242112
    Abstract: The present invention provides an immunogenic composition comprising one or more antigens and a Toll-like receptor (TLR) 7 agonist in an orally (e.g. sublingually) administered composition.
    Type: Application
    Filed: April 25, 2014
    Publication date: August 28, 2014
    Applicant: GlaxoSmithKline Biologicals S.A.
    Inventors: Nadia Ouaked, Martin Plante, Daniel Larocque, Corey Patrick Mallett
  • LIQUID VACCINE PREPARATIONS
    Publication number: 20140242113
    Abstract: This document provides methods and materials involved in making and using liquid vaccine preparations for oral administration. For example, methods and materials for making and using liquid vaccine preparations for oral administration that include a lyophilized or dried vaccine component (e.g., a lyophilized pathogenic agent such as a lyophilized rotavirus preparation) and a liquid edible oil composition (e.g., a liquid edible oil composition containing one or more medium chain triglycerides) are provided. In some cases, liquid vaccine preparations that include a buffer component (e.g., CaCO3) are provided.
    Type: Application
    Filed: April 27, 2012
    Publication date: August 28, 2014
    Inventor: Leonard P. Ruiz, JR.
  • cDNA CONSTRUCT OF SALMONIDAE ALPHAVIRUS
    Publication number: 20140242114
    Abstract: The invention concerns recombinant DNA's comprising cDNA of genomic RNA of a Salmonidae alphavirus preceded by a spacer sequence, under the control of a suitable promoter. Said recombinant DNAs are useful for obtaining expression vectors, producing recombinant Salmonidae alphavirus, and for obtaining vaccines.
    Type: Application
    Filed: October 18, 2013
    Publication date: August 28, 2014
    Inventors: Monique Leberre, Coralie Moriette, Michel Bremont
  • INACTIVATING PATHOGENS WITH OXIDIZING AGENTS FOR VACCINE PRODUCTION
    Publication number: 20140242115
    Abstract: The present disclosure provides methods for producing a vaccine composition containing a pathogen that is rendered noninfectious by exposure to hydrogen peroxide. The methods disclosed herein are suitable for the preparation of vaccines for a wide variety of pathogens, including viruses, bacteria and parasites. The disclosure also provides vaccine compositions (medicaments) containing a pathogen inactivated by exposure to hydrogen peroxide. Methods for eliciting an immune response in a subject by administering vaccine compositions containing a hydrogen peroxide inactivated pathogen are also provided.
    Type: Application
    Filed: May 5, 2014
    Publication date: August 28, 2014
    Applicant: Oregon Health and Science University
    Inventors: Mark K. Slifka, Shirley Villadiego, Erika Hammarlund, Paul Yoshihara
  • Spray Dried Compositions and Methods of Use
    Publication number: 20140242116
    Abstract: Provided herein are insoluble particles that include polypeptides. The polypeptides may have immunogenicity that is greater than the immunogenicity of the same polypeptides when they are not present in the particle. The polypeptides may be soluble before incorporation into the particles and insoluble after incorporation into the particles. The particles may include lipopolysaccharide, wherein the lipopolysaccharide is insoluble. The particles may include a carrier. In one embodiment, a carrier is present at no greater than 0.001 mg carrier/mg particles. In one embodiment, a carrier is present at a ratio of carrier to polypeptide (weight:weight) of no greater than 0.05:1. In one embodiment, a carrier is not detectable in the particles.
    Type: Application
    Filed: May 6, 2014
    Publication date: August 28, 2014
    Applicant: Life-Science Innovations, LLC
    Inventors: Bobby Gene Poe, III, Jared Randall Huisinga
  • Vaccine Composition Capable of Inducing Memory Antibody Response from Single Point Immunization
    Publication number: 20140242117
    Abstract: The present investigation relates to entrapment of carbohydrate antigen such as Vi polysaccharide of Salmonella typhi in poly (DL) lactide (PDLLA) and polylactide-co-glycolide (PLGA) polymer particles. The formulated product not only elicits primary antibody titers from single dose application but also evokes memory antibody titer against the T independent antigen.
    Type: Application
    Filed: May 29, 2012
    Publication date: August 28, 2014
    Applicant: National Institute of Immunology
    Inventors: Anish Chakkumkal, Amulya Kumar Panda
  • Tumor Vaccination in Combination with Hematopoietic Cell Transplantation for Cancer Therapy
    Publication number: 20140242118
    Abstract: In one aspect, the present invention provides a method for treating cancer comprising tumor cell vaccination in combination with hematopoietic and immune cell transplantation. In some embodiments, the method involves autologous tumor cell vaccination prior to autologous hematopoietic and immune cell transplantation. In another aspect, the present invention provides a method of purifying tumor cells from a subject in preparation for vaccination.
    Type: Application
    Filed: July 3, 2013
    Publication date: August 28, 2014
    Inventors: Samuel Strober, Alexander Filatenkov
  • AMINO ALCOHOL DERIVATIVES FOR THE TREATMENT OF DEMYELINATING PERIPHERAL NEUROPATHIES
    Publication number: 20140242119
    Abstract: The invention provides the use of compound of formula V or formula VI in the treatment of a demyelinating peripheral neuropathy: wherein X, R1, R2, R3, R4, R5, n, R1a, R2a, R3a, R4a, R5a, R6a, R7a, Xa and na are defined herein; or the N-oxide derivatives thereof or prodrugs thereof, or a pharmaceutically acceptable salt, solvate or hydrate thereof. The invention further provides combinations of a compound of Formula V or VI with one or more therapeutic agents and pharmaceutical composition thereof.
    Type: Application
    Filed: April 18, 2014
    Publication date: August 28, 2014
    Applicant: NOVARTIS AG
    Inventors: David LEPPERT, Erik WALLSTROEM, Barbara NUESSLEIN-HILDESHEIM
  • SUBSTITUTED AROMATIC COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES
    Publication number: 20140242120
    Abstract: The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein Y, L, A, W1, W2, and R?1 are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
    Type: Application
    Filed: May 8, 2014
    Publication date: August 28, 2014
    Applicant: Synta Pharmaceuticals Corp.
    Inventors: Shoujun Chen, Lijun Sun, Yu Xie
  • NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS
    Publication number: 20140242121
    Abstract: The present invention relates to a compound of Formula I: or an enantiomer, diastereomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Application
    Filed: October 3, 2012
    Publication date: August 28, 2014
    Applicant: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • Crystalline Glycopyrrolate Tosylate
    Publication number: 20140242122
    Abstract: Salts of glycopyrrolate, including solid forms thereof are herein disclosed. Methods of making glycopyrrolate salts and methods of treating hyperhidrosis with salts of glycopyrrolate are disclosed.
    Type: Application
    Filed: September 11, 2013
    Publication date: August 28, 2014
    Applicant: Dermira, Inc.
    Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER
  • SACCHARIDE-PEPTIDE HYDROGELS
    Publication number: 20140242123
    Abstract: The disclosure provides for saccharide-peptide based hydrogels, the functionalization of the saccharide-peptide based hydrogels with one or more biological agents, and the encapsulation of one or more biological materials and/or pharmaceutical agents in the hydrogels. The disclosure further provides for the use of the saccharide-peptide based hydrogels in treating a disease or disorder in a subject.
    Type: Application
    Filed: February 21, 2014
    Publication date: August 28, 2014
    Inventors: Zhibin Guan, Yoko Mullen, Sophia W. Liao
  • Agonists of Guanylate Cyclase and Their Uses
    Publication number: 20140242124
    Abstract: This invention provides a method of colonic cleansing.
    Type: Application
    Filed: February 25, 2014
    Publication date: August 28, 2014
    Inventors: Dennis Riff, Gary S. Jacob, Kunwar Shailubhai, Patrick H. Griffin
  • MUSCLE TISSUE REGENERATION USING MUSCLE FIBER FRAGMENTS
    Publication number: 20140242125
    Abstract: The invention is directed to methods and compositions for obtaining uniform sized muscle fiber fragments for transplantation. These muscle fiber fragments are able to reconstitute into long fibers that are oriented along native muscle. The implanted muscle cells integrate with native vascular and neural network, as confirmed by histology and immunohistochemistry. This invention is particularly advantageous because autologous muscle can be harvested from a donor site, processed and injected into target sites in the operating room. The fragmented muscle fibers can be readily integrated within the host.
    Type: Application
    Filed: August 15, 2012
    Publication date: August 28, 2014
    Applicant: WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: Anthony Atala, James Yoo, In Kap Ko
  • Dendritic Macroporous Hydrogels Prepared By Crystal Templating
    Publication number: 20140242126
    Abstract: The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.
    Type: Application
    Filed: May 14, 2014
    Publication date: August 28, 2014
    Inventors: Scott Zawko, Christine Schmidt
  • Compositions With Thermally-Regulating Material
    Publication number: 20140242127
    Abstract: Cosmetic compositions for topical application to the skin comprising at least one phase change material (PCM) in combination with a cosmetically compatible carrier, and methods for maintaining the skin of a wearer of a cosmetic product at a comfortable temperature, are provided.
    Type: Application
    Filed: February 24, 2014
    Publication date: August 28, 2014
    Applicant: ELC Management LLC
    Inventors: Akira Yokozeki, John R. Castro, Scott Miselnicky
  • COMPOSITE POWDER AND METHOD FOR PRODUCING SAME
    Publication number: 20140242128
    Abstract: An object of the present invention is to provide a composite powder that is stable even if it is present in water for a long time. A composite powder, comprising: an inorganic powder; a first coating layer containing a water-repellent organic compound on the surface of the inorganic powder; and a second coating layer which contains at least one compound selected from the group consisting of silicon oxide, silicon oxide hydrate, aluminum oxide, and aluminum hydroxide, and which is formed on the first coating layer.
    Type: Application
    Filed: August 1, 2012
    Publication date: August 28, 2014
    Applicant: Sakai Chemical Industry Co., Ltd.
    Inventors: Takuro Ashida, Nanae Gouda
  • PHOTOPROTECTIVE PERSONAL CARE COMPOSITION
    Publication number: 20140242129
    Abstract: A photoprotective personal care composition. The invention to a photoprotective personal care composition. The invention more particularly relates to a sunscreen composition that not only provides high sun protection but does that with minimal or no amount of traditionally used organic sunscreens. It is thus objects of the present invention to obviate the drawbacks of the prior art and provide high SPF photo-protective sunscreen compositions. Another object of the present invention is to achieve the above object using negligible amounts or no amount of organic sunscreen agents, which are sometimes unstable with the added advantage that inclusion of low or no organic sunscreens enables low formulation cost.
    Type: Application
    Filed: August 21, 2012
    Publication date: August 28, 2014
    Inventors: Kumar Gaurav, Praveen Kumar, Bharath Palanisamy
  • SEAWEED-DERIVED COSMETIC COMPOSITIONS
    Publication number: 20140242130
    Abstract: A cosmetic composition is disclosed for applying to skin. The composition includes a liquid and dispersed in the liquid: any amount or form of fucoidan, any amount or form of beta glucan; and any amount of a marine extract. When the cosmetic composition is applied to the skin, the appearance of the skin is improved.
    Type: Application
    Filed: May 2, 2014
    Publication date: August 28, 2014
    Inventor: Gina Athwal
  • Composition Containing a Cellulose Derived Capsule With a Sunscreen
    Publication number: 20140242131
    Abstract: A sunscreen composition comprised of one or more sunscreen active agents encapsulated in a cellulose derived capsule wherein the composition can contain one or more additional agents. A sunscreen composition can be mixed with a bodywash, shampoo, conditioner, lotion, gel, soap, cream, hand sanitizer, spray or mousse and can be used by an individual during their normal hygiene processes, such as during a shower or bath or while applying a body product to their skin or hair.
    Type: Application
    Filed: May 3, 2014
    Publication date: August 28, 2014
    Applicant: COLABS INTERNATIONAL CORPORATION
    Inventor: Laura E. Cohen
  • Composition Containing a Cellulose Derived Capsule With a Sunscreen
    Publication number: 20140242132
    Abstract: A sunscreen composition comprised of one or more sunscreen active agents encapsulated in a cellulose derived capsule wherein the composition can contain one or more additional agents. A sunscreen composition can be mixed with a bodywash, shampoo, conditioner, lotion, gel, soap, cream, hand sanitizer, spray or mousse and can be used by an individual during their normal hygiene processes, such as during a shower or bath or while applying a body product to their skin or hair.
    Type: Application
    Filed: May 3, 2014
    Publication date: August 28, 2014
    Applicant: CoLabs International Corporation
    Inventor: Laura E. Cohen
  • ENCAPSULATED LOW VISCOSITY HYDROPHOBIC LIQUID ACTIVES
    Publication number: 20140242133
    Abstract: The present invention provides personal care compositions, as well as methods for protecting low viscosity hydrophobic liquid actives.
    Type: Application
    Filed: May 8, 2014
    Publication date: August 28, 2014
    Inventors: David L. Malotky, Xiaodong Zhang
  • COSMETIC COMPOSITION
    Publication number: 20140242134
    Abstract: The invention relates to cosmetic compositions comprising a water-in-oil emulsion comprising hydrophobically modified particles, amino functionalized silicone and water; the cosmetic composition further comprising a viscosity modifying agent and optical light modifying agent. The invention further relates to a method of modifying the optical appearance of skin comprising the step of applying to the skin the cosmetic composition of the invention.
    Type: Application
    Filed: October 16, 2012
    Publication date: August 28, 2014
    Applicant: CONOPCO, INC. D/B/A UNILEVER
    Inventors: Ezat Khoshdel, Su Yuan, Qiqing Zhang
  • COMPOSITIONS FOR INHIBITION OF INSECT SENSING
    Publication number: 20140242135
    Abstract: In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitos. Method of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: April 25, 2012
    Publication date: August 28, 2014
    Applicant: Vanderbilt University
    Inventors: Laurence Zwiebel, Gregory M. Pask, David C. Rinker, Ian M. Romaine, Gary A. Sulikowski, Paul R. Reid, Alex G. Waterson, Kwangho Kim, Patrick L. Jones, Robert W. Taylor
  • SPRAY APPARATUSES, USES OF DIATOMACEOUS EARTH, AND METHODS OF CONTROLLING INSECT POPULATIONS
    Publication number: 20140242136
    Abstract: There is disclosed a spray apparatus for holding contents comprising diatomaceous earth and a compressed propellant for propelling the diatomaceous earth. There is also disclosed use of diatomaceous earth to control a population of bedbugs, wherein the diatomaceous earth comprises remains of pennate diatoms. There is also disclosed a method of controlling a population of insects, the method comprising causing a compressed propellant to propel diatomaceous earth on a surface. Method of manufacturing a spray apparatus and methods of preparing diatomaceous earth for use in controlling a population of insects are also disclosed.
    Type: Application
    Filed: March 21, 2014
    Publication date: August 28, 2014
    Inventor: Roderick William Phillips
  • Glycolate Formulation for Preserving Wood and Like Materials
    Publication number: 20140242137
    Abstract: Compositions and methods for use in treating, in particular, lignocellulosic substrates such as lumber, are provided; wherein said compositions comprise a preservative or biocidal species, other than boron, in the form of a glycolate. The methods may be used for the purpose of, for example, preventing the growth of pest organisms, or for providing other specific properties to the substrate.
    Type: Application
    Filed: July 27, 2012
    Publication date: August 28, 2014
    Applicant: Matterworks One Limited
    Inventor: Nigel Paul Maynard
  • Applications Of Microencapsulated Essential Oils
    Publication number: 20140242138
    Abstract: Method for the preparation of microencapsulated essential oils or a formulation thereof for various non-agricultural applications.
    Type: Application
    Filed: May 7, 2014
    Publication date: August 28, 2014
    Applicant: BOTANOCAP LTD.
    Inventors: Amnon Kritzman, Arie Markus, Pnina Strongin, Charles Linder
  • CONTROLLED DRUG DELIVERY
    Publication number: 20140242139
    Abstract: A medical device for placement in a body of a mammal is provided. The medical device comprises (1) a polymeric matrix forming the device and defining a lumen through the device, the matrix comprising polymer macromolecules and defining spaces between the polymer macromolecules; (2) a drug contained within at least some of the spaces of the matrix; and (3) a material contained within at least some of the spaces of the matrix to affect diffusion of the drug out of the polymeric matrix when the medical device is placed in the body of the mammal.
    Type: Application
    Filed: February 26, 2014
    Publication date: August 28, 2014
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Jianmin Li, Weenna Bucay-Couto
  • FABRICATION METHOD FOR STRATIFIED AND LAYERED TISSUE TO REPAIR OSTEOCHONDRAL DEFECTS
    Publication number: 20140242140
    Abstract: Fabrication method for stratified and layered tissue to repair osteochondral defects. In a method of the present disclosure, the method comprises the step of applying a first direction magnetic field to a first quantity of a first collagen solution to align collagen within the first collagen solution in a first direction relative to the first direction magnetic field, forming a first layer of collagen. In a method of generating an aligned collagen layer of the present disclosure, the method comprises applying a first magnetic field at or greater than 0.1 Tesla to a layer of a first collagen solution defining a horizontal plane, within a temperature at or between 2° C. and 45° C., to generate an aligned collagen layer.
    Type: Application
    Filed: February 28, 2014
    Publication date: August 28, 2014
    Applicant: Purdue Research Foundation
    Inventors: Corey P. Neu, Tyler A. Novak, Garrett Shannon
  • Polymeric/Inorganic Composite Materials for Use in Medical Devices
    Publication number: 20140242141
    Abstract: In one aspect, the present invention provides composite coatings for implantable or insertable medical devices. These composite coatings comprise (a) an inorganic portion and (b) a polymeric portion that comprises a poly(vinyl pyrrolidone) (PVP) block.
    Type: Application
    Filed: May 7, 2014
    Publication date: August 28, 2014
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Liliana Atanasoska, Jan Weber, Robert W. Warner
  • CELL SECRETED PROTEINS FOR THE TREATMENT OF MYOCARDIAL INFARCTION
    Publication number: 20140242142
    Abstract: The present invention relates to the use of secreted proteins from mesenchymal stem cells and other cells for the treatment of myocardial infarction. In particular, the invention provides compositions and methods based on secreted proteins from mesenchymal stem cells and the genes encoding them.
    Type: Application
    Filed: June 25, 2012
    Publication date: August 28, 2014
    Applicant: National University of Ireland, Galway
    Inventors: Timothy O'Brien, Frank Barry, Claire Kavanagh
  • ADIPOSE STROMAL VASCULAR FRACTION CELL CONSTRUCTS
    Publication number: 20140242143
    Abstract: Three-dimensional tissue constructs are described, which may be created by isolating adipose-derived stromal vascular fraction (SVF) cells, plating the cells onto a polymer scaffold, and culturing the plated scaffold in a culture of DMEM with approximately 10% FBS.
    Type: Application
    Filed: October 1, 2012
    Publication date: August 28, 2014
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Amanda J. LeBlanc, James B. Hoying, Stuart K. Williams
  • DRUG ELUTING SCAFFOLD FOR KIDNEY-RELATED DISEASE
    Publication number: 20140242144
    Abstract: Methods of treating renal cancers and other kidney-related inflammatory disorders with a bioabsorbable polymer scaffold (such as a stent) are described. The treatments are provided as alternative to complete or partial surgical removal of a diseased kidney.
    Type: Application
    Filed: April 30, 2014
    Publication date: August 28, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Krishanankutty Sudhir, Joanne M. Ferguson
  • CHITOSAN NANOFIBER FOR ANIONIC PROTEIN DRUG DELIVERY, METHOD OF PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION FOR TRANSMUCOSAL ADMINISTRATION COMPRISING THE CHITOSAN NANOFIBER
    Publication number: 20140242145
    Abstract: A chitosan nanofiber for delivering an anionic protein drug, a method of preparing the same, and a pharmaceutical preparation for transmucosal administration including the chitosan nanofiber are provided. The chitosan nanofiber including an anionic protein drug in a core and chitosan in a shell is prepared by coaxial electrospinning an aqueous solution of the anionic protein drug through an inner nozzle and a solution of the chitosan or a chitosan derivative through an outer nozzle.
    Type: Application
    Filed: January 2, 2014
    Publication date: August 28, 2014
    Applicant: KNU-INDUSTRY COOPERATION FOUNDATION
    Inventors: Hyuk Sang YOO, Ji Suk CHOI, Younghee KIM, Jihyun KANG
  • FILAMENT BASED ON HYALURONIC ACID IN THE FORM OF FREE ACID AND METHOD FOR OBTAINING IT
    Publication number: 20140242146
    Abstract: The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following steps: a) preparing a spinnable aqueous solution of hyaluronic acid or of a hyaluronic acid salt, preferably a sodium hyaluronate solution; b) extruding said solution to an extrusion die; c) forming the filament by passing the extruded solution into a bath of acetic acid, concentrated to more than 80%, drawing and drying. The invention also relates to a filament based on hyaluronic acid in free acid form, said filament having swelling properties in water and physiological liquids and moreover being solubilizable in water under certain conditions.
    Type: Application
    Filed: May 5, 2014
    Publication date: August 28, 2014
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON I
    Inventors: Alain DOMARD, Laurent DAVID, Florence DUPASQUIER