Abstract: An ophthalmologic imaging apparatus includes: a first optical system that applies an accommodation stimulus to a subject's eye; a tomographic image forming unit that includes a second optical system that splits light from a light source into signal light and reference light, and detects interference light between the signal light having travelled via the subject's eye and the reference light, and creates a tomographic image of the subject's eye based on a detection result of the interference light; and an analyzer that compares a first tomographic image with a second tomographic image to acquire change information indicating a change in a tissue of the subject's eye due to an accommodation stimulus change. The first and second tomographic images are respectively created by the tomographic image forming unit for the subject's eye, to which first and second accommodation stimuli are respectively applied by the first and second optical systems.

Abstract: An ophthalmologic apparatus comprises a light source 12, an optical measurement system 13 that radiates first light from the light source to inside an eye to be examined and guides first reflected light from the eye, an optical reference system (24, 22) that radiates second light from the light source to a reference surface and guides second reflected light from the reference surface, a photo detector 26 that detects interfering light between the first reflected light from the optical measurement system and the second reflected light from the optical reference system, and a processor that determines a position of a measuring portion of the inside of the eye based on the detected interfering light. The optical measurement system comprises an incident angle changing member 46 that changes an incident angle of the first light radiated to the eye within a predetermined angular range relative to an axis of vision of the eye.

Abstract: In one embodiment, a wavefront sensor is combined with a slit lamp eye examination device so that real time aberration values of an eye being examined can be viewed during a slit lamp eye examination session.

Abstract: A method, apparatus and computer program product are provided for iris recognition using natural light. A method is provided for receiving, at a user device, a plurality of iris images. The iris images are captured using natural light. The method also includes generating a composite iris ring based on the plurality of iris images, receiving an iris pattern, comparing the composite iris ring to the iris pattern, and determining a match probability based on the comparison of the composite iris ring to the iris pattern.

Abstract: An accessory frame for selectively coupling components to an optical microscope for imaging of a subject is provided. The optical microscope has a body including an undercarriage. The accessory frame includes a mounting plate that attaches to the undercarriage of the microscope. The mounting plate includes a first attachment port and a second attachment port. The first attachment port is configured to couple a first optical assembly in an optical path of the microscope between an objective lens of the microscope and the subject. The second attachment port is configured to couple a second optical assembly to the microscope body with at least a portion of the optical path of the second optical assembly being outside of the optical path of the microscope.

Abstract: The present invention essentially consists of an integrated system that allows acquisition and quantitative analysis of high-resolution images of the retina. The integrated system includes an optical device and a software app. The optical device is a smartphone-adapted lens for acquisition of high-resolution images of the retina. The software app is a smartphone app for quantitative analysis of the retinal images acquired through the hardware component of the device. The computation is carried out by means of cloud-based technologies. Quantitative indices of retinal damage are obtained. These indices are proven for being relevant for both clinical and research purposes.

Abstract: The invention relates to a medical device in combination with an optical reading device comprising at least one sensor, a meter display for displaying a matrix of pixels and a meter control unit adapted for controlling the meter display so that at least one measurement value measured by the sensor and/or a value derived thereof is encoded in an optical machine-readable signal, wherein the optical reading device is adapted to read the optical machine-readable signal from the medical device, to decode the optical machine-readable signal and to generate a message corresponding to the decoded optical machine-readable signal.

Abstract: Method and apparatus for providing a data stream generator that generates a data stream associated with a monitored analyte level, and a radio frequency logic portion operatively coupled to the data stream generator, the radio frequency logic portion configured to generate a radio frequency data stream based on the data stream generated from the data stream generator, the radio frequency logic portion further including one or more finite state machines and a plurality of discrete digital logic circuits, the one or more finite state machines configured to control the plurality of digital logic circuits to generate the radio frequency data stream for wireless communication are provided. Systems and kits incorporating the same are also provided.

Abstract: A multispectral nevoscope that uses specific wavelengths in the visible and infrared spectrum of electromagnetic radiation to transilluminate a skin-lesion or a biological tissue or specimen for imaging and maps multispectral 2-dimensional images into 3-dimensional virtual space for providing 3-D distributions of pre-defined parameters representing the characteristic properties (such as melanin, hemoglobin and deoxyhemoglobin, etc.) of a skin lesion. Methods are disclosed for analyzing and using the characteristic distributions of specific parameters for detection and management of skin-cancers, or characterization of a biological tissue or specimen.

Abstract: An imaging apparatus for diagnosis and a control method of an imaging apparatus for diagnosis are disclosed, which acquire line data represented by multiple luminance values in a radial direction from a rotation center position of an imaging core, which are derived by a rotation position and movement of the imaging core. Then, based on the acquired line data, an image of a two-dimensional space in which ? representing a rotation angle and z representing a position in a movement direction are set to two axes is generated and displayed.

Abstract: Provided is an optical imaging probe that is able to obtain a stable observation image by a dynamic pressure bearing. An optical imaging probe for guiding rearward a light entering a front end includes: a rotation driving source (10) adapted to drive and rotate a rotor (11); a tubular rotation shaft (20) inserted and fixed over an axial direction in a rotation center side of the rotor (11); an optical fiber (30) inserted in the tubular rotation shaft (20), the front end of which a light is able to enter; and a bearing member (41, 42) supporting the tubular rotation shaft (20) in a rotatable manner, and the bearing member (41, 42) configures a dynamic pressure bearing adapted to generate a high lubricating oil film pressure locally at multiple positions in a circumference direction.

Abstract: A rectal near infrared (NIR) scanning polarization imaging system uses NIR Photonic Prostatoscopy Analyzer (NIRPPA) for prostate cancer detection using light. The NIRPPA consists of a portable rectal NIR scanning polarization imaging unit and an optical fiber-based rectal probe capable of recording sets of 2D images of a prostate through rectum at different wavelengths and depths and obtaining a three dimensional (3D) image of the prostate and 3D locations of abnormal tissue inside the prostate. Diode lasers/light emission diodes (LEDs) with selected emitting wavelengths are used in the NIR spectral range from 650 nm to 2,400 nm corresponding to the four tissue optical windows (#I, 650 nm-950 nm; #II, 1,100 nm-1,350 nm; #III, 1,600 nm-1,870 nm; and #IV, 2,100 nm-2,300 nm). The fingerprint absorptions of water (H2O), Oxyhemoglobin (HbO2) and deoxyhemoglobin (Hb) in the prostate are used as native biomarkers for prostate cancer detection.

Abstract: During an intraoral scan session, a processing device receives a first intraoral image of a dental site and identifies a candidate intraoral area of interest from the first intraoral image. The processing device receives a second intraoral image of the dental site and verifies the first candidate intraoral area of interest as an intraoral area of interest based on comparison of the second intraoral image to the first intraoral image. The processing device then provides an indication of the intraoral area of interest during the intraoral scan session.

Abstract: An object is inserted through a first opening of a bed, and a probe is disposed which includes a breast support member supporting a plurality of first acoustic wave detection elements, which receive an acoustic wave propagated from the object and output a first reception signal so that the first acoustic wave detection elements are oriented to a predetermined area. The probe is separated from the object inserted through the first opening of the bed in the normal direction of the opening surface of the first opening. The bed holds a plurality of second acoustic wave detection elements that receive the acoustic wave propagated from the object and output the second reception signal, and orient the second acoustic wave detection elements to the predetermined area.

Abstract: A method of radiometric image generation is provided using a series of isochronous revolutions of a multi-beam antenna with a dispersion characteristic. The antenna is combined with a multi-channel receiver with frequency channel separation to form an imaging unit. The method comprising cyclically executing the following phases: two separate calibration phase; using first and second standards; external radiation reception phase; data processing phase and data transformation phase.

Abstract: A sensor, sensor pad and sensor array for detecting infrasonic signals in a living organism is provided. The sensor, sensor pad and/or array can be utilized for detecting, determining and/or diagnosing level of stenosis, occlusion, or aneurysm in arteries, or other similar diagnosis. The sensor can include unique circuitry in the form of a piezoelectric plate or element sandwiched between two conductive O-rings.

Abstract: A method of providing a medical image by using a medical imaging apparatus includes: acquiring blood vessel information indicating information about a blood vessel, the blood vessel being included in a medical image; and displaying the medical image. The blood vessel information includes at least one of a first diameter of the blood vessel, a first angle of the blood vessel, and a presence of at least one of bifurcation and crossover, in a first region of interest (ROI) with respect to a first position in the medical image. The acquiring of the blood vessel information includes acquiring blood vessel information corresponding to a second ROI with respect to a second position, based on the blood vessel information corresponding to the first ROI.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating a physiological condition of the vessel are disclosed. One embodiment includes obtaining, at a first time, a first image of the vessel, the image being in a first medical modality, and obtaining, at a second time subsequent to the first time, a second image of the vessel, the image being in the first medical modality. The method also includes spatially co-registering the first and second images and outputting a visual representation of the co-registered first and second images on a display. Further, the method includes determining a physiological difference between the vessel at the first time and the vessel at the second time based on the co-registered first and second images, and evaluating the physiological condition of the vessel of the patient based on the determined physiological difference.

Abstract: A coverlet, or overlay, that contains sensors, electronics and communications systems that measures a subject's physiological condition, accommodates multiple additional add-on sensors, and transmits the data and information from the coverlet to a receiving device, which further transmits information, via wireless infrastructure, or otherwise, to data aggregators, including the Internet and Cloud.

Abstract: An exemplary embodiment of a hemodynamics measurement apparatus can include a PWTT measuring device configured to measure a pulse wave transit time, a body posture measuring device configured to measure a body posture of a living body, and a data calculation device configured to calculate data for measuring a hemodynamics value from the measured pulse wave transit time and body posture of the living body. Also, a hemodynamics measurement method can include measuring a pulse wave transit time and a body posture of a living body, and calculating data for measuring a hemodynamics value from the measured pulse wave transit time and body posture of the living body.

Abstract: Described herein are methods, systems, and software for monitoring blood pressure. In some embodiments, a using a mobile device is used. The blood pressure monitoring system utilizes heart rate measurements at two separate locations on the body to calculate a differential pulse arrival time which is used to estimate blood pressure. The heart rate measurements can be taken simultaneously, or they can be taken sequentially while simultaneously taking ECG measurement. If taken sequentially, the heart rate measurements are aligned with the ECG to determine the differential. Accurate, inexpensive, and discreet blood pressure monitoring is thus provided.

Abstract: A nerve monitoring system facilitates monitoring an integrity of a nerve.

Abstract: Electrical sensing/stimulation apparatuses for positioning at least one electrode within body tissue are provided. An electrical sensing/stimulation apparatus may comprise an elongate lead body having at least one internal lumen, at least one sensing/stimulation electrode, a deployable/retractable displacement member that moves or biases at least one electrode towards a prescribed direction by the user, a tissue attachment mechanism for affixing the distal segment of the device to body tissue, and an atraumatic distal lead body termination. In a retracted configuration, the attachment mechanism is positioned substantially within the distal segment of the lead body, and in the deployed configuration, the attachment mechanism extends from the axis of the lead body to engage body tissue.

Abstract: A computer implemented method for processing measurement data from electrocardiogram, ECG, electrodes on a subject. The method includes obtaining a 3D anatomical model of the torso of the subject, and obtaining a 3D image of the torso of the subject. The three dimensional image is aligned with the three-dimensional model. A position of each electrode in the three-dimensional model is determined from the three dimensional image. The positions of the electrodes in the three dimensional model are used for estimating the distribution, fluctuation and/or movement of electrical activity through heart tissue.

Abstract: Disclosed are a system and a method for potentiating effective brainwaves by controlling volume of sound.

Abstract: For the continuous, non-invasive measurement of temperatures in a tissue, a current is supplied to the tissue by means of at least one feed electrode. A voltage (U) caused by the current (I) is measured by means of at least one measuring electrode and from this the resistance or the magnitude of the impedance of the tissue through which the current flows is determined. The temperature in the tissue is determined directly from the resistance and/or the magnitude of the impedance.

Abstract: An exemplary system, method and computer-accessible medium can be provided for alerting a patient of a condition(s) during an MRI scan procedure(s), which can include, for example receiving information related to the condition(s), and controlling an intensity of a light source(s) located near or on an MRI scanner based on the condition(s). The light source(s) can include a light-emitting diode, which can be a white LED and/or a rainbow LED. The color of the rainbow LED can be changed based on the condition(s). The light source(s) can be located inside or outside a bore of the MRI scanner.

Abstract: A system and method for MR imaging is disclosed. The method causes an RF coil assembly and plurality of gradient coils to apply a fast spin echo (FSE) pulse sequence comprising a preparation segment and a plurality of refocusing segments. The FSE pulse sequence generates a pair of echoes is generated in each of the plurality of refocusing segments that comprises a first echo generated by magnetization pathways having an even number of phase inversions and a second echo generated by magnetization pathways having an even number of phase inversions. MR signals are acquired from the first echo and the second echo and an image of at least a portion of a subject of interest is reconstructed from the acquired MR signals.

Abstract: A pulsed ultra-wideband sensor comprises a control unit designed for forming a time delay of a synchronizing pulse, a probing signal forming path, a transmitting antenna, a receiving antenna, a path of a probing signal transmitter, with an output of said path being connected to the transmitting antenna, a path of a return signal receiver, with an input of the path being connected to the receiving antenna, and a first electronic switch. The input of the first electronic switch is connected to the output of the path for forming a probing signal, and its outputs—to the input of the path of the probing signal transmitter and to the path of a return signal receiver. The outputs of the channels for processing a return signal, which are parts of the path of the return signal receiver, are connected to the path for calculating a respiratory rate and a heart rate.

Abstract: Systems and methods for monitoring nutritional uptake of an individual are disclosed. The method can include monitoring microflora intestinal gas concentration levels associated with a patient and adjusting the volume of nutrient provided by the patient with an artificial feeding device based at least in part on the microflora intestinal gas levels associated with the patient. A microflora intestinal gas sensor can be used to monitor the microflora intestinal gas associated with the patient. The microflora intestinal gas sensor can monitor the microflora intestinal gas in a patient's exhaled breath or in the patient's digestive tract. The microflora intestinal gas sensor be included as part of an enteral feeding system at the distal end or outside end of an enteral feeding tube. Systems and methods for monitoring nutritional uptake of an infant based on microflora intestinal gas levels associated with the infant are also disclosed.

Abstract: Systems and methods for monitoring pulmonary edema and/or pulmonary congestion are based on changes in impedance parameters that are indicative of lung impedance of a patient. Early detection of changes in the status of a patient pertaining to pulmonary edema and/or pulmonary congestion may be especially beneficial for heart failure patients. Quantification is based on differentials, e.g. within a span of 24 hours, of one or more lung impedance parameters.

Abstract: Systems, devices and methods for analyzing the movement, orientation, and location of patients and other users within a hospital, nursing home, or other setting where patient monitoring is desired. One or more sensors or markers are positioned on the body of the user, and a plurality of readers or transceivers in known relative location within the patient care environment detect or communicate with the sensors or markers to identify user location. Location sensing techniques include multi-angulation, multi-lateration, scene analysis (such as visual image analysis), or proximity. Analysis techniques used include time-of-flight analysis, signal strength analysis, image, and video analysis.

Abstract: A method for preventing a viral related infection includes obtaining a sample from a person, assaying the sample to determine whether the person has been previously infected with a virus, and if the person has not been previously infected, providing the person with at least one sensor positioned to detect when a person's hand approaches a predetermined position related to the ground or their own body. By warning the person of undesired hand-to- face contacts, the person is able to reduce the incidence of viral related infections.

Abstract: An apparatus and process for measuring the motion of internal joint structures during and for measuring the function of muscles involved with the motion of a joint of a subject are disclosed. The apparatus can be configured in three forms: a horizontal, vertical, or butterfly motion control device. Each configuration comprises a static member and a moving member, in which the moving member operates to move or be moved by the subject being studied. Also disclosed are processes for using each apparatus to measure of the relative motion of skeletal structures in a subject, in which the subject is positioned in the apparatus and commanded to move while diagnostic medical images are taken or captured. Additionally, processes for using each apparatus to specifically measure and collect data on the function of the subject's muscles are disclosed.

Abstract: A magnetic resonance device includes a radiofrequency unit that includes a radiofrequency antenna, at least one radiofrequency line and at least one radiofrequency injection point. Radiofrequency signals are transferred to the radiofrequency antenna by the at least one radiofrequency line and are coupled into the radiofrequency antenna at the at least one radiofrequency injection point. The magnetic resonance device also includes a patient receiving zone that is at least partially enclosed by the radiofrequency antenna, and a motion detection unit for detecting a movement of a patient that may be positioned within the patient receiving zone. At least one radiofrequency line includes at least one injection element by which at least one motion detection signal of the motion detection unit is coupled into the radiofrequency line.

Abstract: A motion information processing apparatus according to an embodiment includes obtaining circuitry, detecting circuitry, and calculating circuitry. The obtaining circuitry obtains depth image information containing coordinate information and depth information of a subject present in a three-dimensional space. The detecting circuitry detects a part of the subject from the depth image information on the basis of the depth information. The calculating circuitry calculates angle information indicating motion in the rotating direction of the part detected from the depth image information by using the coordinate information of the part.

Abstract: A system and method are provided for capturing hearing characteristics from self-administered hearing tests, including loudness tolerance levels at different sound frequencies, as an individualized shaped auditory profile for automatically enhancing audio to complement and address as closely as possible an individual's hearing deficits experienced via a particular signal pathway, the signal pathway including the audio device used to administer the test, the sound environment, and the user's hearing capabilities. The user may self-administer a hearing test on a convenient personal apparatus, such as a smartphone. The shaped auditory profile may then be used to produce enhanced sound subsequently transmitted to the individual via the same signal pathway. In certain of its aspects, the invention is useful for any individual seeking an enhanced hearing experience, whether having hearing within normal range or hearing that is impaired.

Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.

Abstract: The application concerns a handheld medical instrument for analyzing a body fluid, comprising a housing having a cassette compartment for receiving an exchangeable tape cassette, a transport mechanism comprising a manual drive which can be actuated by a user for rotating a tape spool of the tape cassette, such that a test tape of the tape cassette is wound forwards and functional elements stored thereon are provided for successive use, a stop device acting on the transport mechanism for a targeted stop of the test tape in a functional position of a functional element.

Abstract: Specially designed collection strips and their processing. By using specially designed collection strips, having a backer and one or more absorbent pads, in conjunction with a unique processing method, the processes of analyzing biological samples such as blood, or the like, may be done efficiency with the elimination of cross contamination risk. Identification of the sample stays with the sample throughout the process as it resides on the collection strip. The strip absorbs a known volume. The sample with identification is placed directly in an elution solution, without mechanically separating the sample from its identification information. Elimination of the need for mechanical separation tends to reduce cross contamination, as well as reducing sample processing time.

Abstract: A micro-fluidic device is defined including a channel for conveying blood fluid. A container is defined within the channel for capturing debris generated from the puncture of skin.

Abstract: In some embodiments, the present invention generally relates to the separation of blood within a device to form plasma or serum. In some embodiments, the present invention generally relates to the removal of fluids, such as blood, contained within a device. In one aspect, the present invention is generally directed to systems and methods for receiving blood from a subject and processing the blood to form plasma or serum. For example, a device may be applied to the skin of a subject to receive blood from the subject and pass the blood through a separation membrane, which separates the blood into plasma and a portion concentrated in blood cells. As another example, blood or plasma may be allowed to clot within the device and serum (the unclotted portion of the blood) may be withdrawn from the device. The device may contain, in some cases, a vacuum source such as a pre-packaged vacuum to facilitate receiving of blood and/or passage of the blood through the separation membrane to produce plasma or serum.

Abstract: In order to evaluate a motor-function disorder accompanying a brain disease by a non-conventional new method, a brain function evaluation system 1 is provided with: a display device 11 for displaying a mark indicated by a subject X; an indicated position identification unit 14 for identifying an indicated position on the display device 11 indicated by the subject X; and a divergence quantity calculation unit 16 for calculating a divergence quantity between a display position of the mark and the indicated position indicated by the subject X.

Abstract: In conjunction with the so-called “wagon wheel effect”, based on the Shannon-Nyquist signal processing theory, which our apparatus produces and measures under specific conditions, observed with one (left, right) or two eyes, when a disk reaches a speed , at which normal brain processes perceive as a rotation speed inversion, we create complex sounds or sound variations, which can be heard from one (left, right) or two ears, which we use to test in various scenarios individual's responses (potentially illustrating aspects of brain lateralization function) to support the establishment of a normative theory and measure specific populations (aging population, individuals suffering from mental illness such as Alzheimer, possibly in their early stage of development) against this norm.

Abstract: A system to prevent the creation of pressure-wounds in a subject is provided, comprising at least one pressure detection mat comprising at least one layer of an insulating material sandwiched between first and second layers of conducting and a second layer of conducting strips overlapping at a plurality of intersections forming sensors, a driving unit configured to supply electrical potential selectively to the first layer' conducting strips, a control unit wired to the second layer's conducting strips and configured to control the driving unit and to receive data from the sensors, a processor configured to monitor electrical potential on the second layer's conductive strips to calculate impedance values and determine accumulated pressure applied thereto by calculating a summation of pressure measured by the sensor at predetermined intervals, and at least one display configured to present indications of pressure distribution and accumulated pressure.

Abstract: An apparatus (100, 100?) is configured such that passage of a fluid (30) through an open port (136, 2604) of a distal probe tip (112, 112?) enables detection of a substance (116) that may be present on a surface (31, 33), e.g., a surface of a tooth, based on measurement of a signal correlating to a substance at least partially obstructing the passage of fluid (30) through the open port (136, 2604). The apparatus (100, 100?) includes a proximal pump portion (124) and at least one distal probe portion (110) configured to be immersed in another fluid (11), e.g., water in toothpaste foam. A corresponding system (3000) includes one or two such apparatuses (3100, 3200). A method of detecting the presence of a substance on a surface includes probing an interaction zone (17) for at least partial obstruction of flow of the fluid (30) through the distal probe tip (112, 112?). The distal probe tip (112, 112?) may have a structural configuration for preventing blocking of the open port (136, 2604).

Abstract: Systems and methods described herein relate to a sleep diagnostic system including a mattress assembly, a plurality of sensors, data acquisition circuitry, an input device, a sleep processor, and a display device. The mattress assembly may have a sleeping surface, and the plurality of sensors may be disposed within the mattress assembly below the sleeping surface. The sensors are configured to measure at least one sleep condition and output data signals indicative of the sleep condition. The sleep processor receives signals from both the sensors and one or more other input devices, and determines a sleep characteristic based upon these received signals. The display device, which includes circuitry and a graphical user interface, receives the sleep characteristic from the sleep processor and displays it to the user.

Abstract: The present disclosure provides devices for decreasing the incidence of Cesarean childbirth by managing the labor process. In one aspect, a tactile feedback device is positioned adjacent the perianal tissues. A perianal support device includes a perianal support member having a pressure surface configured for engagement with tissue adjacent an anal orifice and a pressure detecting system associated with the perianal support member to detect pressure indicative of pressure on the perianal tissue of a patient.

Abstract: A compression treatment device includes a pressure sensor system. The pressure sensor system includes at least one sensor cluster positioned relative to a body part, wherein each sensor cluster includes a plurality of pressure sensor elements. Further, each sensor cluster includes at least one pressure sensor element or group of pressure sensor elements connected in parallel with another pressure sensor element or group of pressure sensor elements, and at least one pressure sensor element or group of pressure sensor elements connected in series with another pressure sensor element or group of pressure sensor elements.

Abstract: A method for assessing fluid flow in a conduit includes sensing the fluid flow with a sensor and generating data from the sensor that relates to the sensed fluid flow. The data is output from the sensor and filtered so that it may be interpreted to characterize the fluid flow. The conduit may be a prosthesis such as stent, a stent-graft or a prosthetic vascular graft and the flow may be any body fluid such as blood, bile, or cerebrospinal fluid.