Abstract: Anchor deployment systems, anchor deployment devices, and methods of treatment are described herein. An embodiment of an anchor deployment system comprises a deployment device, a retention mechanism, an anchor, and a connector. The deployment device has a handle, an elongate member, a stylet, a spring, and an actuator. The deployment device has a first configuration in which the connector is releasably attached to the handle and a second configuration in which the connector is free of attachment to the handle.

Abstract: A suture anchor including a first portion and a second portion. The first portion defining a first suture bore and having an angled distal surface that extends in a plane oblique to a longitudinal axis of the suture anchor. The second portion defining a second suture bore and having an angled proximal surface that is complementary to the angled distal surface. The angled proximate surface extends in a plane oblique to the longitudinal axis. In a first configuration, the first portion and the second portion are aligned along the longitudinal axis, and the first suture bore is aligned with the second suture bore. In a second configuration, the first portion and the second portion are offset with respect to the longitudinal axis, and the first suture bore is offset from the second suture bore to retain a suture within the first suture bore and the second suture bore.

Abstract: A soft tissue repair device. The device includes an inserter having a distal portion, a first anchor carried externally onto the distal portion, a second anchor carried externally onto the distal portion, and a flexible strand coupling the first and second anchors and forming an adjustable knotless loop.

Abstract: A medical tube is disclosed, which includes a tubular main body curved in a circular arc shape. The main body has a flat shape as a cross-sectional shape at a central portion in the longitudinal direction thereof. The main body has a flat shape including a minor axis and a major axis as a cross-sectional shape at the central portion in the longitudinal direction thereof. The angle formed between the minor axis and a plane containing both a center point of the circular arc in the central portion and a center point of the cross-sectional shape with respect to the longitudinal direction of the main body is an acute angle. The angle is preferably 20° to 60°. The medical tube thus configured is for use in treatment of a disorder in a pelvic organ, by indwelling an implant between a urethral lumen and a vaginal cavity.

Abstract: A member of a rigid flexible elastic material, the member including a body portion and an aperture portion with the member adapted for delivery through an axial longitudinal channel of a percutaneous delivery subsystem, the aperture portion including an expanded mode having a lateral dimension greater than an inner diameter of the channel when the aperture portion extends outside the channel and a collapsed mode wherein the lateral dimension is not greater than the inner diameter of the channel when the aperture portion is within the channel, the channel including a first axial opening and a second axial opening with the aperture portion transitioning from the expanded mode to the collapsed mode when inserted into the openings and the aperture transitioning from the collapsed mode to the expanded mode when exiting from the openings.

Abstract: The problem that a metal wire joined integrally to a hole formed in a proximal end face of a medical suture needle is susceptible to bending damage is reduced. A suture needle A has a blind hole 5 which is formed in a proximal end face 3, inserts the end of a wire 10 thereinto, and joins the wire 10 thereto by caulking, and a counterbore 6 which is formed on the proximal end face 3 side of the blind hole 5 and has a dimension D at least in the proximal end face 3 larger than a dimension d of the blind hole 5 and a depth L smaller than a depth of a caulked portion with respect to the blind hole 5. A suture needle with wire inserts the end of the wire 10 into the blind hole 5 to caulk the outer circumference of the suture needle corresponding to the blind hole 5, thereby integrally joins the wire 10 thereto.

Abstract: A medical tube is disclosed, which can include a main body in which a distal portion of a tubular proximal separable piece is detachably connected to a proximal portion of a tubular distal separable piece; and a state maintaining mechanism for maintaining a connected state of the distal separable piece and the proximal separable piece. In addition, the main body is inserted into a body starting from the distal separable piece side, and is disposed inside the body in a state in which a distal end and a proximal end thereof are exposed outside of the body. In addition, the state maintaining mechanism can include a string which is disposed inside the main body and interlocks the distal separable piece and the proximal separable piece, and the connected state can be released by cutting the string.

Abstract: The invention concerns delivering paired magnetic anastomosis devices to either side of tissues to be joined. The magnetic anastomosis devices are coupled to a guide element that facilitates delivery and manipulation of the devices when using minimally-invasive techniques such as endoscopy and laparoscopy. Elongated manipulators and guide tubes are also disclosed that improve a user's dexterity with the devices during placement.

Abstract: A circular stapling instrument including a stapling forming assembly that is actuated independently from actuation of the cutting assembly is provided. The instrument includes a handle assembly, an elongate body extending from the handle assembly, a cartridge assembly mounted on a distal end of the elongate body. The cartridge assembly includes a pusher assembly and a knife assembly. The knife assembly is selectively fixed relative to the pusher assembly.

Abstract: A stapling apparatus includes a body portion, a staple cartridge disposed within the body portion, and a buttress removably attached to the staple cartridge. The staple cartridge includes a plurality of staple receiving slots defined in a tissue contacting surface of the staple cartridge, with each staple receiving slot of the plurality of staple receiving slots including a staple disposed therein. The buttress includes a plurality of tabs at an outer edge of the buttress. The buttress is releasably retained on the staple cartridge by at least one tab of the plurality of tabs extending into a staple receiving slot of the plurality of staple receiving slots defined in the staple cartridge.

Abstract: A device for performing a remote ischemic conditioning treatment. The device includes an inflatable cuff and a cartridge which is a source of gas for inflating the cuff. A first valve controls the flow of gas from the cartridge to the cuff so as to maintain a predetermined pressure in the cuff during an ischemic period. A second valve allows gas to escape from the cuff during a reperfusion period of the remote ischemic conditioning treatment. A controller which may be battery-powered is used to control the opening and closing of the valves. The cartridge may contain a gas, or materials which, under certain conditions, react to produce a gas. The chemical reaction may be initiated by an electrical pulse or signal from the controller.

Abstract: In some aspects, the present disclosure is directed to vaso-occlusive devices comprise a device portion and one or more expandable components which comprise a shape memory material and which expand laterally outward from the device portion upon being subjected to an activating stimulus. Other aspects of the disclosure pertain to systems containing such devices and methods of forming vascular occlusions using such devices.

Abstract: Inventive subject matter disclosed herein includes a coil assembly for treating a vascular malformation, comprising: a flat wire coil comprising Palladium, having an optimum packing density, that is coiled and that is detachable attachable to the flat wire coil.

Abstract: An expandable device can be delivered to a luminal structure in a patient using a delivery system. The delivery system can include an elongate carrier member and an engagement component that can releasably engage the expandable device. The elongate carrier member can have a distal portion, a central axis, and a first notch in the distal portion. The engagement component can be positioned within the first notch. Further, the expandable frame can be coupled to the distal portion of the carrier member and have a first terminal end section. When coupled to the carrier member, the first terminal and section can (i) pass from a first end of the first notch through a space between the central axis and the engagement component and (ii) terminate outside of the first notch, beyond a second end of the first notch.

Abstract: Devices, systems, and methods are disclosed for inverting and closing a left atrial appendage. Certain methods include the steps of inverting a distal portion of a left atrial appendage and constraining the inverted portion using at least a snare device configured to be fit around the inverted portion of the left atrial appendage and closed, so that the inverted portion is securely circumscribed and closed. Devices and systems related to such methods are also described and include a catheter system comprising a vacuum tube and a snare slidably disposed within a catheter.

Abstract: An occlusion system (5) provides a trimmable continuous embolic coil (10) that is “cut to length” at the end of its deployment into the target occlusion site. A delivery device (15) provides the “cut to length” feature for the continuous embolic coil.

Abstract: An embolic implant for treating aneurysms or other vascular disorders may include a cover component of unitary construction that is disposed about the exterior of a microcoil such that it does not extend into a lumen formed by the coil. The cover can enhance packing volume and density per unit length of coil, and can prevent blood flow and cause blood clotting while not risking rupture of the vascular disorder. The cover may also provide a platform for the application of multiple treatments and/or therapies including, for example, functionalized and/or bioactive coatings, drug coatings, gene therapy, thrombogenicity control coatings, and surface modifications, while preserving key coil performance attributes.

Abstract: A device is provided that aids in the medical compression process. One example of such a device is a medical compression device that can be added to medical machinery, such as the Hologic® Multicare Prone Biopsy table or a Hologic® upright biopsy table/system. The device can be configured to be placed into and partially through an “operating window” of a compression paddle component used in the biopsy table. The device advantageously does not require modification of the biopsy table or modification of the compression paddle/guide for use.

Abstract: A disposable tourniquet and its method of use is disclosed. The tourniquet is in the form of a band formed of a thin flexible, non-stretchable material and is arranged to be wrapped around the patient's limb, tightened and locked in place to reduce circulation. The tourniquet includes a removable portion which includes indicia bearing information, e.g., instructions for use, promotional materials, etc. The removable portion may be in the form of an envelope or pouch for holding some item therein. The removable portion may form a tearable portion of the band or may comprise a panel or patch adhesively secured to the band. The tourniquet also may include at least one usage-evidencing seal.

Abstract: Methods for resecting a portion of a knee joint are described herein. While the described methods can comprise any suitable step, in some implementations, the methods include cutting a cylindrically-shaped hole in a portion of the knee joint selected from at least one of a distal portion of a femur and a proximal portion of a tibia in the knee joint; and using a depth of the cylindrically-shaped hole as a reference point to resect bone around the cylindrically-shaped hole to a depth substantially matching the depth of the cylindrically-shaped hole. Other implementations are described.

Abstract: Embodiments of apparatuses and methods for microfracture (e.g., forming a plurality of microfractures in a bone to encourage cartilage regeneration).

Abstract: Embodiments of apparatuses and methods for microfracture (e.g., forming a plurality of microfractures in a bone to encourage cartilage regeneration).

Abstract: A medical drill is disclosed, which is made of amorphous alloy, the amorphous alloy is a Ti-based amorphous alloy which comprises titanium in 40 at % or above, wherein the tensile strength of the medical drill is 1600-2600 MPa, and the Vicker's hardness of the medical drill is 600-800.

Abstract: Handles configured to be removably coupled to IO devices that are also configured to be coupled to powered drivers. Kits including IO devices and the present handles. Methods of using the present handles and IO devices.

Abstract: Method and devices for cutting and removing a portion of a tissue composition which includes cancellous bone which is directly or indirectly impinging on a neural structure of the spine by creating channels through the tissue structure and then removing the detached tissue.

Abstract: One embodiment disclosed provides a guide instrument for controlling the depth and trajectory of a surgical access device into a bone.

Abstract: A guide apparatus having a body having a central axis defined therethrough and a first channel and a second channel formed therethrough, a handle coupled to the body, the handle having a locking mechanism configured to prevent movement of the body relative to the handle in a first direction along the central axis of the body, and an arm coupled to the handle, the arm configured to engage at least a portion of a bone.

Abstract: Templating software can determine and visually depict the location and size of cuts in a trochanteric osteotomy, including an extended trochanteric osteotomy. The software can also calculate the size and area of fixation for a newly implanted prosthesis, based upon which the new prosthesis that will be implanted in a particular patient can be selected. Additionally, an adjustable cut guide can stabilize and guide the cuts during the procedure.

Abstract: Temporary, radiographically opaque, bone markers having first and second penetration members that are concentric with one another and are configured to pierce bone are provided herein. Bone markers can non-exclusively be used to help verify the correct surgical site along the vertebrae, locate the vertical midline, and as a fixed point for aligning surgical instruments. Insertion and extraction devices for use with the bone markers are also provided herein.

Abstract: Devices, systems, and methods are generally provided for guiding surgical devices into a desired location and orientation in a bone. In general, the devices can include an elongate guide, a sleeve having an inner lumen therethrough for seating the guide, and a locking mechanism configured to lock a position of the guide with respect to the sleeve. The guide can have a distal, bone-engaging portion that can be laterally offset from an intermediate portion of the guide by a predetermined distance and that can extend distally beyond the sleeve to contact a bony structure. The guide can thus orient and stabilize the sleeve at the predetermined distance from the bony structure to provide for the delivery of one or more surgical devices through the sleeve and into the bone at a desired location and orientation, without requiring a surgeon to actually view the surgical site.

Abstract: A method for removing a stone from a patient comprising the steps of: providing a suction evacuation assembly which includes a sheath and one or more side arms; inserting and positioning a distal end of the sheath into a lumen or cavity of a patient's body containing a stones; connecting a tube to one of the side arms and to a collection bottle; connecting another tube to the collection bottle and a negative pressure system; visualizing the stone or foreign body using a scope inserted through the assembly; activating the negative pressure system in order to remove the stone from the cavity if the diameter of the stone is narrower than an inside diameter of the sheath and the side arm, or performing a lithotripsy on the stone to create fragments with a decreased diameter which allow the passage through the assembly; and collecting the stone in the collection bottle.

Abstract: The present invention relates generally to devices and methods for retrieving or manipulating objects within a lumen. More specifically, embodiments of the invention relate to devices and methods for retrieving or manipulating medical devices from a body lumen. One embodiment of the present invention provides a novel and improved retrieval snare and method of fabricating and using the same. The snare includes a snare wire, having a distal end and a proximal end, for use in the human anatomy, such as but not limited to blood vessels, pulmonary airways, reproductive anatomy, gastrointestinal anatomy, and organs such as the kidneys or lungs. The device enables a user to capture a foreign object located within the human anatomy, grasp said object in a controlled manner, and retrieve and remove said object from the human anatomy.

Abstract: The present invention relates generally to devices and methods for retrieving or manipulating objects within a lumen. More specifically, embodiments of the invention relate to devices and methods for retrieving or manipulating medical devices from a body lumen. One embodiment of the present invention provides a novel and improved retrieval snare and method of fabricating and using the same. The snare includes a snare wire, having a distal end and a proximal end, for use in the human anatomy, such as but not limited to blood vessels, pulmonary airways, reproductive anatomy, gastrointestinal anatomy, and organs such as the kidneys or lungs. The device enables a user to capture a foreign object located within the human anatomy, grasp said object in a controlled manner, and retrieve and remove said object from the human anatomy.

Abstract: The present invention relates generally to devices and methods for retrieving or manipulating objects within a lumen. More specifically, embodiments of the invention relate to devices and methods for retrieving or manipulating medical devices from a body lumen. One embodiment of the present invention provides a retrieval device having a retrieval snare and an ultrasound transducer to assist in the intravascular navigation of the device. The device enables a user to capture a foreign object located within the human anatomy, grasp said object in a controlled manner, and retrieve and remove said object from the human anatomy.

Abstract: A vessel-occluding medical device for the use in diagnosis and/or treatment of cardiovascular disease in the human body includes an outer tube, an inner tube slidably housed within the outer tube, and a tubular sleeve comprising a generally U-shaped, direction reversing region, which moves along the length of the tubular sleeve, to assume radially contracted and radially expanded state as the inner and outer tubes move between the first and second positions. When the tubular sleeve is in the radially expanded state, the inner portion of the tubular sleeve has a funnel-shaped surface and a longitudinally-extending opening to permit material to pass therethrough for receipt of material into the inner tube.

Abstract: An intracorporeal pressure shock wave device to provide treatment within blood vessels artificial vessels and grafts that includes a frontal pressure shock wave reflector positioned at the distal end of an intracorporeal catheter to direct shock waves toward a treatment target, such as an occlusion and clot.

Abstract: Electrohydraulic lithotripters comprising a plurality of electrohydraulic probes are disclosed. Each probe of the plurality of probes comprise a first electrode and a second electrode positioned at a distal end of the probe such that when the probe is discharged, an electric arc between the first electrode and the second electrode produces a shockwave that radiates from the distal end of the probe. A first probe and a second probe of the plurality of probes may be configured to discharge simultaneously or sequentially.

Abstract: A clot retrieval system comprises a clot retrieval device, a catheter 51, and a tubular shield element 61. The clot retrieval device comprises an elongate member 53 having a proximal end and a distal end, and a clot engaging element 54 at the distal end of the elongate member 53 the clot engaging element 54 having a collapsed delivery configuration and an expanded deployed configuration. The catheter is adapted for placement at a location at which a distal end of the catheter is proximal of the clot engaging element and the tubular shield element 61 extends over the elongate member 53 and is adapted for location between the distal end of the catheter and the proximal end of the clot engaging element 54. The tubular shield element 61 is movable relative to the elongate member 54 when the clot engaging element is in the expanded configuration in that the force that is applied on retraction of the elongate member is spread over the outer surface of the tubular shield element.

Abstract: A medical apparatus may include an inflatable tubular component that can be inflated into a U-shaped structure, a plurality of connecting portions formed on a main body. In one embodiment, the connecting portion can be used for inflating an inflatable cylindrical component formed in the U-shaped structure. The medical apparatus treatment may further include a plurality of control filaments disposed on an inner surface of the U-shaped structure to control the size thereof, so the inner surface of the U-shaped structure can tightly press against an outer surface of the inflatable cylindrical component when it is inflated, and a chamber is formed in the U-shaped structure next to the inflated cylindrical component. When in use, the stones can be trapped into the chamber and chemical reagents can be introduced to either dissolve or disrupt the stones.

Abstract: A surgical device comprises an elongate shaft having an outer tube and an inner rod positioned in the outer tube. The outer tube and inner rod each comprise a distal end and a proximal end. An actuator is operably connected to the proximal ends of the outer tube and the inner rod. An end effector is adapted for in vivo attachment to and detachment from the elongate shaft. The end effector comprises an outer casing comprising a first detent mating feature adapted to engage the distal end of the outer tube; an inner shuttle axially moveable relative the outer casing, the shuttle comprising a second detent mating feature adapted to engage the distal end of the inner rod; and a pair of surgical jaws having an opened position and closed position dependant on the relative axial position of the shuttle and casing. A tubular loader is sized to receive the end effector, the tubular loader comprising third detent mating feature adapted engage end effector.

Abstract: A switch mechanism for a medical manipulator, the switch mechanism including a moveable switching operation part, moving-side contacts provided to the switching operation part, and fixed-side contacts capable of contacting the moving-side contacts. At least the electrical-contact sections of the moving-side contacts and of the fixed-side contacts are formed from a corrosion-resistant material.

Abstract: The present invention provides a cell eradication method and a cell eradication principle for necrotizing a cell by agitating a cell using a physical turning force from the impression of an AC magnetic field, after preparing a magnetic nanowire having a dipole and introducing the magnetic nanowire into a cell. Therefore, the composition for inducing cell eradication of the present invention, when applied to a cell that is requested to be removed such as a cancer cell, can eradicate the cell by applying a physical impact through the rotation of the nanowire introduced inside the cell. Additionally, the heat generated from induced current from the magnetic field impression can add an effect of thennotherapy, and also, attaching a drug to the surface of the nanowire enhances the treatment effects.

Abstract: A surgical cutting instrument comprises an outer tubular member having a proximal section, an intermediate section and a central lumen. An inner tubular member is rotatably received within the central lumen and includes a distal end forming a cutting member extending distally beyond, and exposed relative to, the distal section of the outer tubular member. A bearing assembly is coupled to the outer tubular member and the inner tubular member.

Abstract: According to one aspect, a device for assisting in removing an implanted lead is provided. The device comprises a body portion having a center adapted to accommodate the lead, a cutting component coupled to the body portion to assist in separating tissue from the lead, and at least one anchoring component disposed at least partially within the body portion, the at least one anchoring component capable of providing pressure on the lead that resists movement of at least part of the body portion along the lead at least in part by applying fluid pressure.

Abstract: Methods and systems for removing an object, such as a lead, from formed tissue are provided. Specifically, a lead removal sleeve is configured to engage patient formed tissue at a dilation engagement point. The lead removal sleeve is configured to dilate the formed tissue around a lead, while providing an inner lumen with clearance for the lead to move within the sleeve. It is an object of the lead removal sleeve to support the formed tissue, and even forces of the formed tissue, with a structure of the sleeve as the lead is removed from a patient. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures.

Abstract: A laparoscopy tool includes a sheath and a control wire slideably disposed within a lumen of the sheath. The sheath has a diameter of less than 1.6 mm and is introduced through an abdominal incision. A handle axially displaces the control wire within the lumen and operates a conventional tip with wire-controlled opposing jaws that is introduced through the umbilicus and has a bore formed in its trailing end. A first set of blades in the bore engage grooves formed in the leading end of the control wire and a second set of blades engages the sheath to prevent sheath retraction. A cam displaces the second set of blades away from the sheath for sheath introduction and removal, and toward the sheath to prevent sheath retraction. The tip is removed through the umbilicus and the tool is removed through the abdominal incision when the surgery is completed.

Abstract: An ultrasonic instrument comprises an ultrasonic transducer, an acoustic waveguide, and an ultrasonic blade. The acoustic waveguide comprises a bore extending through the waveguide, an anchor pin, and an acoustic isolator. The anchor pin is insertable through the bore and is operable to longitudinally anchor the acoustic waveguide relative to the ultrasonic instrument. The acoustic isolator is radially disposed about the acoustic waveguide and is operable to acoustically isolate the acoustic waveguide from the ultrasonic instrument. The acoustic isolator comprises an opening extending through the isolator. The opening is configured to receive the anchor pin. The ultrasonic blade is in acoustic communication with the acoustic waveguide such that the ultrasonic transducer is operable to drive the ultrasonic blade to vibrate ultrasonically via the acoustic waveguide.

Abstract: An apparatus includes a monolithically-constructed transmission member that defines a lumen along a longitudinal axis. The transmission member includes a first portion, a second portion, and a third portion. The first portion is configured to be coupled to an ultrasonic energy source. The second portion is configured to contact a bodily tissue to transfer ultrasonic energy from a first portion into the bodily tissue. The third portion is disposed between the first portion and the second portion and defines a cross-sectional moment of inertia that is less than at least one of a cross-sectional area moment of inertia of the first portion or a cross-sectional moment of inertia of the second portion.

Abstract: A rotational atherectomy device including a drive shaft rotatably extending through an outer tubular member to rotate a cutting member positioned at a distal end thereof. The rotational atherectomy device further includes an elongate penetrator extendable distal of the cutting member a predetermined maximum distance and configured to stabilize the cutting member as the cutting member engages an occlusion to control the trajectory and advancement of the cutting member through the occlusion.

Abstract: Provided is an apparatus, a system and method for use in image guided medical instrument manipulation. Embodiments describe various apparatuses having a mount operable to receive an imaging probe, a body guide and a medical instrument guide. There are also described methods and a systems for using the various apparatuses to position the apparatus and collect data relating to the position of the medical instrument relative to a target within a patient's body. Further methods include using the apparatus and system in epidural anaesthetic procedure or lumbar puncture. The apparatus may include a hand-held ultrasound probe, configured to acquire a volumetric dataset representing a 3-D depiction of a volume, which may include information about a medical instrument's position relative to the target in three dimensions.