Patents Issued in February 11, 2016
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Publication number: 20160039703Abstract: A glass lens blank for polishing in which a thickness of a defect-containing layer is suppressed to a minimum and thus it is possible to shorten the processing time required for grinding and polishing the glass lens blank for polishing after press-molding, a method of manufacturing the same, and a method of manufacturing an optical lens. A glass lens blank for polishing of which at least a main surface is a press-molding surface, wherein a defect-containing layer formed on the main surface has a thickness of 50 ?m or less.Type: ApplicationFiled: February 25, 2014Publication date: February 11, 2016Applicant: HOYA CORPORATIONInventors: Mikio IKENISHI, Akihiro SHOJI, Yoshitake TANNO, Isao TANAKA
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Publication number: 20160039704Abstract: A cartridge assembly includes a hub portion having a first end and a second end, a first retaining ring portion including a first snap ring and a first retaining ring member, and a second retaining ring portion including a second snap ring and a second retaining ring member. The cartridge assembly further includes a plurality of disc elements positioned between the first retaining ring portion and the second retaining ring portion, where the plurality of disc elements has an outer diameter that is greater than an outer diameter of the first retaining ring portion and the second retaining ring portion, and a plurality of fastening members positioned at the first end and the second end of the hub portion, the plurality of fastening members extending radially inward from the hub portion.Type: ApplicationFiled: August 7, 2014Publication date: February 11, 2016Inventors: Ralph Alfred Langensiepen, Brandon Thomas Sternquist, Lewis Kirk Klingensmith, Eric Joseph Teator, Izhar Zahoor Ahmed, Do-Hun Lee
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Publication number: 20160039705Abstract: With conventional bent glass plates and fabricating method thereof, it has been difficult to fabricate bent glass plates with high productivity while achieving both high shape precision and high surface smoothness. According to the present invention directed to a glass plate with 2 mm or less thickness, a bent glass plate for optical use with a shape precision PV value of 50 um or less and a surface roughness Ra value of 5 nm or less was achieved by appropriately controlling the temperature of the glass plate, the temperatures of upper and lower press dies, and the press pressure; and quickly and uniformly cooling the glass plate to a predetermined temperature.Type: ApplicationFiled: August 6, 2015Publication date: February 11, 2016Inventors: Satoshi KATO, Koji SEGI, Nobuhiro MAEDA
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Publication number: 20160039706Abstract: A method for supporting a heated glass sheet in connection with a glass processing operation may include adjusting a support structure so that multiple spaced apart support members of the support structure cooperate to define a shape that corresponds to a desired end shape of the glass sheet. The method may further include contacting the glass sheet with the support members until the glass sheet has been sufficiently cooled. Furthermore, the support structure may include a frame and a support assembly associated with the frame, the support assembly including the support members and a support connected to the support members such that at least a portion of each support member is adjustable with respect to the support. The support may further be connected to the frame at two locations on the frame such that the support spans an open area between the two locations on the frame.Type: ApplicationFiled: October 21, 2015Publication date: February 11, 2016Inventors: Dean M. Nitschke, Ashoka G. Jinka, Thomas J. Zalesak, James P. Schnabel, JR., Scott Charles Morrow
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Publication number: 20160039707Abstract: Rotary spinner apparatuses, systems and methods for producing fibers from molten materials are disclosed. Certain exemplary embodiments include rotary spinners including a hub, a slinger, an annular member, a retaining member, and a plurality of fasteners. In certain embodiments the hub, the retaining member, and the plurality of fasteners are structured to limit axial movement of the annular member relative to the hub member and to allow radial expansion and contraction of the annular member relative to the hub member. In certain embodiments the annular member is structured to contact the hub at a plurality of contact areas and is spaced apart from the hub at a plurality of gap areas. In certain embodiments the slinger is structured to contact the hub at a plurality of contact areas and is spaced apart from the hub at a plurality of gap areas.Type: ApplicationFiled: August 7, 2014Publication date: February 11, 2016Inventors: Robert W. Zembrodt, Walter A. Johnson, Paul Wlodarczyk
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Publication number: 20160039708Abstract: Described herein are alkali-free, boroalumino silicate glasses exhibiting desirable physical and chemical properties for use as substrates in flat panel display devices, such as, active matrix liquid crystal displays (AMLCDs) and active matrix organic light emitting diode displays (AMOLEDs). In accordance with certain of its aspects, the glasses possess good dimensional stability as a function of temperature.Type: ApplicationFiled: October 16, 2015Publication date: February 11, 2016Inventors: Adam James Ellison, Timothy James Kiczenski, Shawn Rachelle Markham, John Christopher Mauro
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Publication number: 20160039709Abstract: In glass or chemically tempered glass containing a coloring component, when chromaticity of a major surface is measured on the glass in a state of a glass plate with a 0.8 mm thickness, at least one of an absolute value of a difference (?a*(D65?F2)) and is an absolute value of a difference (?a*(A?F2)) is 2.10 or more, where the difference (?a*(D65?F2)) is a difference between a chromaticity a* value of reflected light by a D65 light source and a chromaticity a* value of reflected light by an F2 light source in an L*a*b* color system and the difference (?a*(A?F2)) is a difference between a chromaticity a* value of reflected light by an A light source and the chromaticity a* value of the reflected light by the F2 light source in the L*a*b* color system.Type: ApplicationFiled: October 16, 2015Publication date: February 11, 2016Applicant: ASAHI GLASS COMPANY, LIMITEDInventors: Hiroyuki YAMAMOTO, Kazuhide KUNO, Makoto SHIRATORI
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Publication number: 20160039710Abstract: The present invention relates to an alkali-free glass substrate, having a strain point of 680° C. or higher, a Young's modulus of 78 GPa or greater, an UV transmittance at a wavelength of 300 nm of from 40% to 85% in terms of 0.5 mm thickness, an in-plane distribution of the UV transmittance at a wavelength of 300 nm in a G6-sized substrate of 1% or less in terms of 0.5 mm thickness, an average cooling rate around the glass transition point obtained according to a rate cooling method of 400° C./min or lower, and an in-plane distribution of the average cooling rate of 40° C./min or less.Type: ApplicationFiled: October 22, 2015Publication date: February 11, 2016Applicant: ASAHI GLASS COMPANY, LIMITEDInventors: Hlrofumi TOKUNAGA, Akio KOIKE, Masaya KUNIGITA
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Publication number: 20160039711Abstract: A conductive paste for forming external electrodes for a multilayer ceramic electronic component. The paste contains a glass composition containing (a) BaO, (b) at least one of SrO and CaO, (c) ZnO, (d) B2O3, and (e) at least one selected from the group consisting of SiO2, Al2O3, and TiO2, in which the total content percentage of BaO, SrO, and CaO is 30 mol % or more, the molar ratio represented by B2O3/(SiO2+Al2O3+TiO2) is 0.7 to 1.5, and the content percentage of ZnO is 0 to 5 mol %.Type: ApplicationFiled: October 19, 2015Publication date: February 11, 2016Inventor: Tomochika Miyazaki
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Publication number: 20160039712Abstract: An electrically conductive glass seal for providing a hermetic bond between an electrically conductive component and an insulator of a corona igniter is provided. The glass seal is formed by mixing glass frits, binder, expansion agent, and electrically conductive metal particles. The glass frits can include silica (SiO2), boron oxide (B2O3), aluminum oxide (Al2O3), bismuth oxide (Bi2O3), and zinc oxide (ZnO); the binder can include sodium bentonite or magnesium aluminum silicate, polyethylene glycol (PEG), and dextrin; the expansion agent can include lithium carbonate; and the electrically conductive particles can include copper. The finished glass seal includes the glass in a total amount of 50.0 to 85.0 weight (wt. %), and electrically conductive metal particles in an amount of 15.0 to 50.0 wt. %, based on the total weight of the glass seal.Type: ApplicationFiled: August 10, 2015Publication date: February 11, 2016Inventors: KEITH FIRSTENBERG, WILLIAM J. WALKER, JR., PATRICK J. DURHAM, JAMES D. LYKOWSKI
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Publication number: 20160039713Abstract: Certain example embodiments of this invention relate to articles including anticondensation and/or low-E coatings that are exposed to an external environment, and/or methods of making the same. In certain example embodiments, the anticondensation and/or low-E coatings may be survivable in an outside environment. The coatings also may have a sufficiently low sheet resistance and hemispherical emissivity such that the glass surface is more likely to retain heat from the interior area, thereby reducing (and sometimes completely eliminating) the presence condensation thereon. The articles of certain example embodiments may be, for example, skylights, vehicle windows or windshields, IG units, VIG units, refrigerator/freezer doors, and/or the like.Type: ApplicationFiled: October 23, 2015Publication date: February 11, 2016Inventors: Jean-Marc LEMMER, Nestor P. MURPHY, David D. McLEAN, Richard BLACKER, Herbert LAGE, Jose FERREIRA, Pierre PALLOTTA
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Publication number: 20160039714Abstract: A method for operating a plant for producing cement clinker from raw meal having, as viewed in the materials flow direction, at least one calciner for deacidifying the raw meal, and at least one rotary kiln for sintering the deacidified raw meal to form cement clinker. The deacidified raw meal, after passing through the calciner, flows via a cyclone preheating stage into the rotary kiln. Exhaust gases are guided from the rotary kiln into a reactor, arranged between the rotary kiln and the calciner, with fuel being fed into the reactor superstoichiometrically in relation to the dwell time of the exhaust gases in the reactor, so that carbon dioxide in the exhaust gases is reduced to form carbon monoxide. The carbon monoxide is used as a reducing agent for nitrogen oxides, which are chemically reduced in the reactor independently of the short dwell time in the calciner.Type: ApplicationFiled: April 4, 2014Publication date: February 11, 2016Applicant: KHD Humboldt Wedag GmbHInventors: Norbert Streit, Marc Feiss
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Publication number: 20160039715Abstract: A process for forming a carbonaceous article for use among particles in a carbonaceous bed of a thermal reactor, includes forming bricks having a material composition including carbon containing particles other than coke, and at least one of Portland cement, potassium silicate cement, and aluminum silicate cement, in an approximate weight % other than water of: 40 to 95 parts of the carbon containing particles, 0 to 20 parts of the Portland cement, 0 to 20 parts of the potassium silicate cement, and 0 to 20 parts of the aluminum silicate cement.Type: ApplicationFiled: October 15, 2015Publication date: February 11, 2016Inventors: James Santoianni, Michael Erskine Heier, Aleksandr Gorodetsky, Stephanie Reese, Kent O. Hicks
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Publication number: 20160039716Abstract: There is provided a Ultra-high performance glass concrete (UHPGC) including between 300 and 1000 kg/m3 of cement, between 0 and 1400 kg/m3 of glass sand (GS), between 0 and 300 kg/m3 of reactive pozzolanic material, between 150 and 900 kg/m3 of glass powder (GP), between 0 and 600 kg/m3 of fine glass powder (FGP), between 5 and 60 kg/m3 of superplasticizer, between 50 and 300 kg/m3 of fiber; and, between 130 and 275 kg/m3 of water, wherein the content of GP is of at least 3 wt % of the UHPGC, and/or the content of GS is of at least 19 wt % of the UHPGC and/or the content of FGP is of at least 0.5 wt % of the UHPGC.Type: ApplicationFiled: March 28, 2014Publication date: February 11, 2016Inventors: Arezki TAGNIT-HAMOU, Nancy SOLIMAN
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Publication number: 20160039717Abstract: A polycrystalline transparent ceramics laminate includes a polycrystalline ceramics laminate made of polycrystalline transparent ceramics. The polycrystalline transparent ceramics contains aluminum oxide. The polycrystalline ceramics laminate may have flat, curved, or spherical surfaces. The polycrystalline ceramics laminate has a top and a bottom opposite to the top. The polycrystalline transparent ceramics laminate has a density greater than 3.5 g/cm3, a surface roughness smaller than or equal to 1 ?m, a transparency at a thickness of 1 mm greater than or equal to 60%, and a refractive index between 1.5 and 2.5.Type: ApplicationFiled: August 11, 2014Publication date: February 11, 2016Inventor: Rong-Fu WU
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Publication number: 20160039718Abstract: A ceramic precursor batch composition comprising inorganic ceramic-forming ingredients, a hydrophobically modified cellulose ether binder having a molecular weight less than or equal to about 300,000 g/mole and an aqueous solvent is provided. The ceramic precursor batch composition has a ratio of binder to aqueous solvent of less than about 0.32. The ceramic precursor batch composition may be used to increase the rate of extrusion of the composition. A method for increasing a rate of extrusion of a ceramic precursor batch composition is also disclosed.Type: ApplicationFiled: October 19, 2015Publication date: February 11, 2016Applicant: Corning IncorporatedInventors: Michael Edward DeRosa, Lung-Ming Wu
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Publication number: 20160039719Abstract: A coating composition for applications at temperatures higher than 1200 degrees C. comprises (a) between 80.0 and 99.9 wt. % of unstabilized zirconia; and (b) between 0.1 and 5.0 wt. % of a liquid phase former which is solid at ambient temperature and either melts or reacts, or decomposes to form a liquid phase above a temperature not lower than 1000 degrees C.; wherein the wt. % are expressed in terms of total solid weight of the coating composition at room temperature. A refractory element that may be made of a carbon bonded refractory comprises a coated surface comprising a first coating of the coating composition as defined above.Type: ApplicationFiled: March 12, 2014Publication date: February 11, 2016Applicant: VESUVIUS CRUCIBLE COMPANYInventor: James Ovenstone
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Publication number: 20160039720Abstract: A method of treating a preceramic material includes providing a preceramic polycarbosilane or polycarbosiloxane material that includes a moiety Si—O—M, where Si is silicon, O is oxygen and M is at least one metal that includes at least one transition metal, and thermally converting the preceramic polycarbosilane or polycarbosiloxane that includes the moiety Si—O—M material into a ceramic material.Type: ApplicationFiled: September 24, 2015Publication date: February 11, 2016Inventor: Wayde R. Schmidt
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Publication number: 20160039721Abstract: A titanium compound-containing core-shell powder includes a plurality of core-shell particles, each of which includes a core body and a shell layer encapsulating said core body. The core body is electrically conductive. The shell layer includes a crystal that is selected from titanate oxides having a perovskite structure and titanate oxides having a spinel structure. The core body and the shell layer are chemically bonded to each other.Type: ApplicationFiled: August 29, 2014Publication date: February 11, 2016Inventor: Masayuki Fujimoto
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Publication number: 20160039722Abstract: Mass production of industrial explosives with one-tenth of the cost of the current production method—Nitric acid 98% removal of the chemical reaction producing explosive materials—Increasing the production safety—Producing ammonium sulfate, a chemical fertilizer, as a byproduct—Supporting the production of different explosives such as TNT, nitroglycerine and etc.—decreasing the acid concentration in the product.Type: ApplicationFiled: August 5, 2014Publication date: February 11, 2016Inventor: Iman Sheikh
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Publication number: 20160039723Abstract: The present invention relates to multifunctional chemosensors that can measure the concentration, enandomeric excess (ee), and absolute configuration of chiral compounds. The chemosensors described herein may contain a backbone moiety that is bonded to a fluorescent moiety and a moiety for bonding a chiral compound. Backbone moieties may include aromatic groups, for example, naphthyl. The chemosensors described herein are useful for measuring concentration, enandomeric excess, and absolute configuration of organic molecules in areas such as high throughput screening.Type: ApplicationFiled: March 14, 2014Publication date: February 11, 2016Applicant: GEORGETOWN UNIVERSITYInventors: Christian Wolf, Keith W. Bentley
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Publication number: 20160039724Abstract: Systems, methods, and devices for producing hydrogen and capturing CO2 from emissions combine both H2 production and CO2 capture processes in forms of thermochemical cycles to produce useful products from captured CO2. The thermochemical cycles are copper-chlorine (Cu—Cl) and magnesium-chlorine-sodium/potassium cycles (Mg—CI—Na/K—CO2). One system comprises a Cu—Cl cycle, a CO2 capture loop, and a hydrogenation cycle. Another system comprises an Mg—CI—Na/K—CO2 cycle and a hydrogenation cycle. Devices for hydrogen production, CO2 capture, hydrogenation, and process and equipment integration include a two-stage fluidized/packed bed, hybrid two-stage spray-fluidized/packed bed reactor, a two-stage wet-mode absorber, a hybrid two-stage absorber, and a catalyst packed/fluidized bed reactor.Type: ApplicationFiled: November 12, 2013Publication date: February 11, 2016Inventors: Greg NATERER, Zhaolin WANG
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Publication number: 20160039725Abstract: Disclosed is a process for starting up fluidized reaction apparatus which are used for producing lower olefins from methanol or/and dimethyl ether. Said process includes after heating the catalyst bed of circulating fluidized catalytic reaction apparatus to above 200° C. or 300° C. by using a starting-up auxiliary heat source, feeding methanol or dimethyl ether raw materials to a reactor, whereby heat released by the reaction makes the temperature of the reaction system apparatus increase quickly to a designed temperature, consequently making the system reach the normal operation state rapidly. Said process is suitable for starting up an exothermic fluidized catalytic reaction apparatus and can simplify the apparatus and operation, accordingly lowering the cost.Type: ApplicationFiled: October 19, 2015Publication date: February 11, 2016Inventors: Zhongmin Liu, Zhihui Lv, Changqing He, Yu Liu, Yue Qi, Xiaojian Min, Gongwei Wang, Xiangao Wang, Jinling Zhang
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Publication number: 20160039726Abstract: Boroaluminosilicate molecular sieve catalysts are provided and are useful for hydrocarbon conversion reactions including isomerization of xylenes in C8 aromatics feedstocks to produce p-xylene. Advantageously, it has been found that the boroaluminosilicate molecular sieve catalysts of the invention are more selective than conventional commercial xylene isomerization catalysts, resulting in reduced formation of transmethylation byproducts (C7 and C9 aromatics) while simultaneously providing a high degree of xylene isomerization.Type: ApplicationFiled: March 12, 2014Publication date: February 11, 2016Applicant: BP Corporation North America Inc.Inventor: Jeffrey Allen AMELSE
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Publication number: 20160039727Abstract: The invention concerns a xylenes isomerization process for the production of equilibrium or near-equilibrium xylenes from a feedstream comprising phenol and/or styrene.Type: ApplicationFiled: October 23, 2015Publication date: February 11, 2016Inventors: John Di-Yi Ou, Shifang L. Luo, Surbhi Jain
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Publication number: 20160039728Abstract: The present invention provides an efficient and cost effect synthesis route from a specific starting material of 2,3-dichloro-1,3-butadiene to the desired product of Z-1,1,1,4,4,4-hexafluoro-2-butene.Type: ApplicationFiled: July 30, 2015Publication date: February 11, 2016Inventors: SHENG PENG, ANDREW JACKSON, MARIO JOSEPH NAPPA
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Publication number: 20160039729Abstract: Disclosed is a process for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of Formula (I): C(X)3CF2C(X)3??(I) to at least one compound of Formula (II) CF3CF?CHZ??(II) where each X and Z is independently H, F, Cl, I or Br, said process preferably not including any substantial amount of oxygen-containing catalyst in certain embodiments. Preferably Z is H.Type: ApplicationFiled: August 10, 2015Publication date: February 11, 2016Inventors: Hsueh S. Tung, Sudip Mukhopadhyay, Michael Van Der Puy, Daniel C. Merkel, Jing Ji Ma, Cheryl L. Bortz, Barbara A. Light, Steven D. Phillips, Kim M. Fleming, Susan A. Ferguson
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Publication number: 20160039730Abstract: The present invention provides a process for purifying a monoterpene or sesquiterpene having a purity greater than about 98.5% (w/w). The process comprises the steps of derivatizing the monoterpene (or sesquiterpene) to produce a monoterpene (or sesquiterpene) derivative, separating the monoterpene (or sesquiterpene) derivative, and releasing the monoterpene (or sesquiterpene) from the derivative. Also encompassed by the scope of the present invention is a pharmaceutical composition comprising a monoterpene (or sesquiterpene) having a purity greater than about 98.5% (w/w). The purified monoterpene can be used to treat a disease such as cancer. The present monoterpene (or sesquiterpene) may be administered alone, or may be co-administered with radiation or other therapeutic agents, such as chemotherapeutic agents.Type: ApplicationFiled: September 2, 2015Publication date: February 11, 2016Inventors: Thomas CHEN, DANIEL LEVIN, SATISH PUPPALI
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Publication number: 20160039731Abstract: The present invention, provides for a deuterium-enriched monoterpene or sesquiterpene such as perillyl alcohol, or a deuterium-enriched isomer or analog of monoterpenes or sesquiterpenes, such as isoperillyl alcohol. The present invention also provides for a deuterium-enriched derivative of a monoterpene or sesquiterpene, such as a perillyl alcohol carbamate or a deuterium-enriched derivative of an isomer or analog of a monoterpene or sesquiterpene, such as an isoperillyl alcohol carbamate. The deuterium-enriched derivative may be perillyl alcohol or isoperillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The present invention also provides for a method of treating a disease such as cancer, comprising the step of delivering to a patient a therapeutically effective amount of a deuterium-enriched compound.Type: ApplicationFiled: November 21, 2012Publication date: February 11, 2016Inventors: Thomas Chen, Daniel Levin, Satish Pupalli
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Publication number: 20160039732Abstract: The invention relates to a method for the purification of natural vanillin, comprising at least one step in which the natural vanillin is evaporated.Type: ApplicationFiled: January 20, 2014Publication date: February 11, 2016Inventors: Hubert GAYET, Denis REVELANT, Martine VIBERT
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Publication number: 20160039733Abstract: The present invention relates to a new method for isolating ingenol (C20H28O5) from mixtures of diterpenoid esters and ingenol esters in a single step. Ingenol isolated by means of this method can be used as a precursor for the synthesis of biologically active ingenol derivatives, such as ingenol-3-angelate and ingenol-3-tigliate.Type: ApplicationFiled: October 26, 2015Publication date: February 11, 2016Inventors: Maria Luz Bellido Cabello De Alba, Giovanni Appendino, Alberto Pagani, Eduardo Munoz Blanco
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Publication number: 20160039734Abstract: Curcumin analogues and methods are provided for treatment of disease.Type: ApplicationFiled: October 20, 2015Publication date: February 11, 2016Inventors: David L. Vander Jagt, Lorraine M. DECK, Steve F. ABCOUWER, Robert A. ORLANDO, Robert E. ROYER, Waylon M. WEBER, Ekaterina V. BOBROVNIKOVA-MARJON, Lucy A. HUNSAKER
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Publication number: 20160039735Abstract: A process utilizing nitric acid and oxygen as co-oxidants to oxidize aldehydes, alcohols, polyols, preferably carbohydrates, specifically reducing sugars to produce the corresponding carboxylic acids.Type: ApplicationFiled: October 20, 2015Publication date: February 11, 2016Inventors: Steven Donen, Kirk Hash, Tyler Smith, Keith Jensen
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Publication number: 20160039736Abstract: The present invention relates to compounds of: or a pharmaceutically acceptable salt thereof, wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(0)-(CH2)n-CH3 or CH(OH)—(CH2)n-CH3 wherein n is 3 or 4; R1 is H, F or OH; R2 is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(0)-(CH2)n-CH3 or CH(OH)—(CH2)n-CH3 wherein n is 3 or 4; R3 is H, F, OH or CH2Ph; R4 is H, F or OH; Q is 1) (CH2)mC(0)OH wherein m is 1 or 2, 2) CH(CH3)C(0)OH, 3) C(CH3)2C(0)OH, 4) CH(F)—C(0)OH, 5) CF2-C(0)OH, or 6) C(0)-C(0)OH; and compositions comprising the same and the method using the same for the prevention or treatment of various fibrotic diseases and conditions in subjects, including pulmonary fibrosis, liver fibrosis, skin fibrosis, renal fibrosis, pancreas fibrosis, systemic sclerosis, cardiac fibrosis or macular degeneration.Type: ApplicationFiled: March 14, 2014Publication date: February 11, 2016Inventors: Boulos ZACHARIE, Shaun ABBOTT, Lyne GAGNON, Pierre LAURIN, Brigitte GROUIX
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Publication number: 20160039737Abstract: The present invention describes the use of soluble metal salts to reduce impurities and metathesis catalysts poisons from olefinic feedstocks to improve olefin metathesis efficiency. The soluble metal salts were added to the olefinic feedstocks to prevent peroxides and catalyst poisons from inhibiting the metathesis catalyst. The soluble metal salts remain in the olefinic feedstocks and are used without further purification in the olefin metathesis reactions. The key to this invention is the soluble metal salt compounds do not inhibit the olefin metathesis catalysts but unexpectedly increase olefin metathesis catalyst efficiency while prior art heterogeneous metal complexes sequester the olefin metathesis catalyst, preventing olefin metathesis.Type: ApplicationFiled: March 14, 2014Publication date: February 11, 2016Inventors: Timothy M. CHAMPAGNE, Thay A. UNG
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Publication number: 20160039738Abstract: Production of methacrylic acid ester comprising a step of having acetone undergo a dehydration reaction in the presence of a dehydration reaction catalyst to obtain a reaction mixture; a step of separating a mixture containing propyne and propadiene as main components from the obtained reaction mixture; a step of separating the separated mixture containing propyne and propadiene as main components into a liquid, gas, or gas-liquid mixture containing propyne as a main component, and a liquid, gas, or gas-liquid mixture containing propadiene as a main component; and a step of bringing the obtained liquid, gas, or gas-liquid mixture containing propyne as a main component into contact with carbon monoxide and an alcohol having 1 to 3 carbon atoms in the presence of a catalyst containing at least one selected from the group consisting of Group 8 metal elements, Group 9 metal elements, and Group 10 metal elements.Type: ApplicationFiled: March 19, 2014Publication date: February 11, 2016Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Kohei SEKI, Tetsuya SUZUTA, Naoki MIURA
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Publication number: 20160039739Abstract: Provided herein are poly-capped estolides, including those of the Formula IV in which n is an integer equal to or greater than 0; m is an integer equal to or greater than 2; R1 is selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; R2 is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R3 and R4, independently for each occurrence, are selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched. Hydroxy estolides are also described herein, which may be suitable end products, or serve as intermediates to provide poly-capped estolides. Also provided are compositions containing poly-capped estolides and methods of making both said poly-capped estolides and compositions thereof.Type: ApplicationFiled: August 7, 2014Publication date: February 11, 2016Inventors: Jeremy Forest, Jakob Bredsguard, Travis Thompson
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Publication number: 20160039740Abstract: The present invention relates to the identification of provided cyclohexane-1,3-diones (CHD compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided CHD compounds.Type: ApplicationFiled: October 20, 2015Publication date: February 11, 2016Inventors: Donald R. Kirsch, Radhia Benmohamed, Anthony C. Arvanites, Richard J. Morimoto, Wei Zhang, Richard B. Silverman
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Publication number: 20160039741Abstract: The present invention relates to novel pyrazole(thio)tetrahydronaphthyl carboxamides, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials.Type: ApplicationFiled: October 21, 2015Publication date: February 11, 2016Inventors: Simon MAECHLING, Mazen ES-SAYED, Peter DAHMEN, Ulrike WACHENDORFF-NEUMANN, David BERNIER, Lionel CARLES, Christophe DUBOST, Jean-Pierre VORS, Stephane BRUNET, Helene LACHAISE
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Publication number: 20160039742Abstract: A process for obtaining (±)-cis-2-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexanol includes the following steps: (a) extracting from roots of Nauclea Latifolia with an appropriate solvent, leading to a crude residue, and (b) purifying the crude residue to obtain a purified residue containing (±)-cis-2-dimethylaminomethyl-1-(3-methoxyphenyl)cyclohexanol.Type: ApplicationFiled: March 26, 2014Publication date: February 11, 2016Inventors: Michel DE WAARD, Ahcène BOUMENDJEL, Germain TAIWE SOTOING
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Publication number: 20160039743Abstract: Disclosed is a compound represented by chemical formula (1): or chemical formula (2):Type: ApplicationFiled: October 21, 2015Publication date: February 11, 2016Inventors: Masashi MITA, Kenji HAMASE, Tsubasa OYAMA
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Publication number: 20160039744Abstract: The present invention provides a process for the preparation of lacosamide in substantially optically pure form, which in one aspect comprises the following steps: (i) resolution of O-methyl-D,L-serine to provide O-methyl-D-serine in substantially optically pure form; (ii) acetylation of O-methyl-D-serine thereby obtained to provide the N-acetyl 10 derivative thereof in substantially optically pure form; (iii) activating the carboxy group of the compound thereby obtained; and (iv) reacting the compound thereby obtained with benzylamine.Type: ApplicationFiled: October 30, 2015Publication date: February 11, 2016Applicant: UCB PHARMA GMBHInventors: Alain Merschaert, Christophe Joseph Szczepaniak, Joerg Hamann, Ralf Kanzler
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Publication number: 20160039745Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.Type: ApplicationFiled: March 10, 2014Publication date: February 11, 2016Inventors: Celia Dominguez, Ignacio Muñoz-San Juan, Michel Maillard, Gilles Raphy, Alan F. Haughan, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Burli, Grant Wishart, Samantha J. Hughes, Daniel R. Allen, Stephen D. Penrose, Perla Breccia
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Publication number: 20160039746Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.Type: ApplicationFiled: October 12, 2015Publication date: February 11, 2016Applicant: DOW AGROSCIENCES LLCInventors: William C. Lo, James E. Hunter, Gerald B. Watson, Akshay Patny, Pravin S. Iyer, Joshodeep Boruwa
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Publication number: 20160039747Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as “AAA compounds”), which, inter alia, are (selective) retinoic acid receptor ? (RAR?) agonists. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to (selectively) activate RAR?, and in the treatment of diseases and conditions that are mediated by RAR?, that are ameliorated by the activation of RAR?, etc., including cognitive disorders, memory impairment, memory deficit, senile dementia, Alzheimer's disease, early stage Alzheimer's disease, intermediate stage Alzheimer's disease, late stage Alzheimer's disease, cognitive impairment, and mild cognitive impairment.Type: ApplicationFiled: October 9, 2015Publication date: February 11, 2016Inventors: Jonathan Patrick Thomas Corcoran, Sarkis Barret Kalindjian, Alan David Borthwick, David Reginald Adams, Jane Theresa Brown, David Michel Adrien Taddei, Jason John Shiers
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Publication number: 20160039748Abstract: Provided is a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: [in the formula, R1 to R5, A, and *1 to *3 are as defined in Description].Type: ApplicationFiled: November 28, 2013Publication date: February 11, 2016Inventors: Takayoshi SUZUKI, Yukihiro ITOH, Daisuke OGASAWARA, Naoki MIYATA, Tamio MIZUKAMI, Ryuzo SASAKI, Akifumi TAKAORI, Masahiro KAWAHARA
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Publication number: 20160039749Abstract: 11a,12-dehydrotetracycline compounds are described.Type: ApplicationFiled: May 23, 2013Publication date: February 11, 2016Inventors: Joel Berniac, Mohamed Y. Ismail, Mark L. Nelson, Farzaneh Seyedi
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Publication number: 20160039750Abstract: The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene.Type: ApplicationFiled: August 4, 2015Publication date: February 11, 2016Applicant: Intrexon CorporationInventors: Robert Eugene HORMANN, David W. Potter, Orestes Chortyk, Colin M. Tice, Glenn Richard Carlson, Andrew Meyer, Thomas R. Opie
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Publication number: 20160039751Abstract: A compound represented by general formula (1) (wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group or the like; R3 represents a hydrogen atom or an optionally substituted C1-6 alkyl group; R4 represents a hydrogen atom, an optionally substituted C1-6 alkyl group or the like; X1 represents an optionally substituted C2-6 alkynylene group or the like; A represents an optionally substituted bivalent aromatic hydrocarbon group or the like; X2 represents an optionally substituted C1-6 alkylene group or the like; Y1 represents an oxygen atom or the like; and R5 represents a hydrogen atom or the like) or a salt thereof is useful as an antibacterial agent.Type: ApplicationFiled: March 14, 2014Publication date: February 11, 2016Applicant: TOYAMA CHEMICAL CO., LTD.Inventors: Muneo SHOJI, Naomi SUGAYA, Naoko YASOBU
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Publication number: 20160039752Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R1 to R3, R5 to R9, A, P, V, W, X, Y and Z are as defined herein.Type: ApplicationFiled: January 8, 2014Publication date: February 11, 2016Inventors: Christine Elizabeth ALLAN, Andrzej Roman BATT, Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, Stephen John PETHEN