Abstract: An instrument for clamping and trimming the bone tendon portion of a graft to a desired size, comprising a pair of elongated handles each having jaws at one end; the handles being hinged together at a pivot point allowing the jaws to open and close in a scissor arrangement, the jaws defining a generally U-shaped trapezoidal receptacle when the jaws are closed about the bone tendon portion of the graft to be trimmed and the jaws comprising respective upper guide surfaces along their upper edges whereby, when a bone tendon portion is positioned in the U-shaped trapezoidal receptacle, the upper guide surfaces function as a guide for a blade of a saw to trim any excess portion of the bone tendon portion protruding above the upper guide surfaces.

Abstract: A transcatheter valve frame comprising a valve frame comprising an elongate tubular member having a longitudinal axis and a circumference, the elongate tubular member comprising a plurality of struts interconnected by peaks and valleys that define a closed cell construction comprising a plurality of interconnected cells, the valve frame is formed from a single piece of material comprising a metal or metal alloy, the valve frame having a diameter that increases upon axial compression and the valve frame comprising a locking mechanism integral with the valve frame configured to fix the diameter of the valve frame.

Abstract: A prosthetic heart valve according to the present disclosure comprises a radially collapsible and expandable annular frame and a leaflet structure comprising a plurality of leaflets mounted within the frame. The frame in particular embodiments can have commissure attachment portions that are configured to support the commissures of the leaflets at locations spaced radially inwardly toward the longitudinal flow axis of the prosthetic valve relative to the frame portions circumscribing the moveable portions of the leaflets. When the leaflets open under pressure of blood flowing through the prosthetic valve, the moveable portions of the leaflets are retained at positions spaced inwardly from the inner surface of the frame to protect against abrasion of the leaflets.

Abstract: A heart valve implant has a body sized and configured to rest near or within a heart valve annulus. A plurality of spaced-apart retainers extend outwardly from the body to contact tissue near or within the heart valve annulus. The retainers are sized and configured to secure the body to the heart valve annulus. The implant can be secured, e.g., without the use of sutures.

Abstract: Implantable prosthetic valves are disclosed, methods of their use, and related fabrication techniques are disclosed. In some cases, the prosthetic valves disclosed herein can include frame, skirt, and valve components. The frame component can have an overall, generally scalloped shape comprising fewer struts and fabricated from less raw material than known frames. In some cases, the prosthetic valves disclosed herein can be crimped to a smaller diameter than can other known valves.

Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. A plurality of commissure features is disposed on the stent and coupled to selected ones of the struts, each commissure feature including a body having a proximal end and a distal end, and at least one eyelet in the body. The heart valve further includes a collapsible and expandable valve assembly including a plurality of leaflets. At least one leaflet is connected to the at least one eyelet and to at least one of the selected ones of the struts via a suture pattern.

Abstract: The disclosure includes an arrangement for a handle for a catheter system that includes a first member and a second member. The handle can include a screw member positioned within the handle and configured for rotation about an axis. The screw member can include an internal thread. A carriage can be positioned within the screw member. The carriage can engage the internal thread and can be coupled to the first member. An alignment member can extend within the screw member to limit rotation of the carriage about the axis as the screw member is rotated. Rotation of the screw member in a first direction about the axis can cause the carriage to move in a first longitudinal direction within the screw member causing the first member to move in the first longitudinal direction relative to the handle.

Abstract: An implantable device system includes an implantable device, such as an annuloplasty ring, for controlling at least a shape and/or size of a heart valve annulus. The implantable device includes an arcuate body and an adjustment system configured to adjust the shape and/or size of the arcuate body. An adjustment tool is configured to be coupled to the adjustment system so that the adjustment tool can be used to activate and control adjustment of the arcuate body. A sensor system is configured to be coupled to the implantable device. The sensor system includes a first sensor configured to measure physiological data at an inflow portion of the valve annulus when the implantable device is implanted into the valve annulus, and a second sensor configured to measure physiological data at an outflow portion of the valve annulus when the implantable device is implanted into the valve annulus.

Abstract: Disclosed herein are annular prosthetic devices, such as annuloplasty rings, that include suture clips integrated into or mounted within an annular frame. The clips can quickly secure to sutures to obviate the need to tied knots in the sutures during implantation. Embodiments comprise an annular frame having an open central region and a plurality of suture clips spaced angularly apart around the frame. Each of the suture clips can comprise two opposing tabs that extend toward each other such that the suture clip forms a gripping region between ends of the tabs and the gripping region is configured to grip a suture inserted through the suture clip between the two tabs. The annular frame and the plurality of suture clips can be formed from a single piece of flat material with the suture clip tabs being formed by laser cutting the piece of flat material, or the suture clips can be movable along a track formed in the annular frame.

Abstract: A brace for mounting to an annulus of a cardiac valve, the brace comprising: first and second bottom gripping wings for gripping the annulus; first and second top gripping wings for gripping the annulus; and a support bridge that connects the top wings to the bottom wings; wherein the brace is deformable from a delivery configuration to a deployed configuration and in the delivery configuration the top wings are oriented substantially back to back along an axis and the bottom wings are oriented substantially back to back along the same axis, and in the deployed configuration the first top and bottom gripping wings face each other to grip the annulus between them and the second top and bottom gripping wings face each other to grip the annulus between them.

Abstract: The device is intended to be positioned in a sealed introducer arranged in the thoracic cavity between two ribs in order to penetrate into the left ventricle, passing through the apex of the heart. According to the invention, the device includes a body having a handle and at least one control member capable of acting on an assembly for installing and securing a braid to the mitral annulus by means of suturing elements, the assembly has a mechanism capable of enabling the extraction of a suture through the mitral valve while also being capable of enclosing the braid and becoming anchored to the periphery of the mitral annulus under the clamping effect of the suture, exerting two opposing pressure-bearing forces.

Abstract: A prosthetic device for implanting in a patient's heart includes (i) a therapeutic device capable of restoring function to a native heart valve; and (ii) at least one sensor including a body, an inductor coil disposed within the body, and a capacitor in communication with the inductor coil, the at least one sensor being coupled to the therapeutic device, and being configured to monitor proper function of the therapeutic device within the patient's heart.

Abstract: Patient-adapted articular repair systems, including implants, instruments, and surgical plans, and methods of making and using such systems, are disclosed herein. In particular, various embodiments include methods of selecting and/or designing patient-adapted surgical repair systems using parameterized models and/or multibody simulations.

Abstract: A composite article (e.g., prosthesis) and method of preparing the article is provided. An article may include a body having a matrix of a first hardness having a plurality of particles of a second hardness embedded in the matrix in fixed locations, the second hardness being harder than the first hardness, and the matrix having an external wear surface with a portion of the particles being proximal to or exposed at the external wear surface. The matrix with the particles may improve the life and durability of the article.

Abstract: An acetabular cup prosthesis comprises at least one recess in an edge of the cup and at least one attachment means. The attachment means has a projecting portion for attachment of the cup to an introducer (configured for insertion of the cup into a patient) and a retaining portion for retaining the attachment means on the cup. The retaining portion is located in a respective one of the recesses and is fixedly secured in the respective recess. A method of manufacture of the cup is also provided.

Abstract: A variable hip resurfacing implant which allows for varying configuration options to account for characteristics of underlying degenerative hip joint disease and for both un-cemented and cemented application. The variable hip resurfacing implant generally includes a femoral head portion, bearing surface, outer rim, inner planar surface, central stem, and a central stem threaded hole.

Abstract: Implant apparatus and methods directed toward treating conditions involving the knee joint and the patella specifically are disclosed. Full range of motion of the knee joint and tissue integrity are maintained in treatment approaches involving implanting a joint surface load reducing implant proximate the joint to change the direction of the tendons or muscles exerting forces on the joints.

Abstract: An orthopaedic knee prosthesis includes a tibial bearing component with surface features which operate to protect adjacent soft tissues of the natural knee throughout a wide range of flexion. More particularly, the tibial bearing component provides an anterior relief space disposed between the dished lateral and medial articular compartments, in which the relief space is convex as viewed from a sagittal perspective across the medial/lateral extent of the relief space.

Abstract: A glenoid implant is provided and may include a body portion and a stem portion. The stem portion may extend from the body portion along a longitudinal axis. The body portion may include an articular side and a bone-engaging side opposite the articular side. At least a portion of the bone-engaging side may be disposed at a non-parallel angle relative to at least a peripheral edge of the articulation side.

Abstract: A medical grade thermoplastic or polymer implant with an osteoconductive coating is provided, specifically for corrections of the distal and proximal interphalangeal toe joints of the foot. The implant can be either straight or angled, and can be either solid or cannulated for insertion. The implant is sized and shaped depending on the specific anatomy and desired correction.

Abstract: Insertion and expansion devices for use in inserting motion discs, and associated methods of use.

Abstract: A device, system, and method are disclosed that supplements a human spinal column's structure by replacing a damaged intervertebral disc with a machined spacer comprising a movable pair of blades that rotate to expand from the spacer in-situ to interlock with a patient's vertebras, and a locking system that provides secondary protection from blade movement within the spacer.

Abstract: An expandable vertebral body replacement is presented. The device has an inner and outer housing longitudinally moveable on one-another which locks in place using a retention member. This can be locked or fortified by several described options. Also presented is a method for expanding said device embodiments and a system for an expandable vertebral body replacement.

Abstract: The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In one embodiment, the fusion device includes a body portion, a first endplate, and a second endplate, the first and second endplates capable of being moved in a direction away from the body portion into an expanded configuration or capable of being moved towards the body portion into an unexpanded configuration. The fusion device is capable of being deployed and installed in both configurations.

Abstract: Spacerless artificial disc replacements (ADR) are disclosed. One preferred embodiment includes two saddle-shaped components to facilitate more normal spinal flexion, extension, and lateral bending while limit axial rotation, thereby protecting the facet joints and the annulus fibrosus (AF). Either or both of the superior and inferior components are made of a hard material such as chrome cobalt, titanium, or a ceramic including alumina, zirconia, or calcium phosphate. The articulating surfaces of the ADR are also preferably highly polished to reduce friction between the components. Metals, alloys or other materials with shape-memory characteristics may also prove beneficial.

Abstract: An artificial disc is disclosed. The artificial disc may include a superior endplate having a bi-convex superior surface and a concave inferior surface, and an inferior endplate having a bi-convex inferior surface. The artificial disc may also include a core assembly disposed between the superior endplate and the inferior endplate, and a support assembly disposed on outer surfaces of both the superior endplate and the inferior endplate. The support assembly may be configured to couple the superior endplate to the inferior endplate.

Abstract: A spacer for separating bones of a joint, the spacer includes a frame having a longitudinal axis, and ramped surfaces. An endplate configured to engage a bone of the joint has ramped surfaces mateable with the ramped surfaces of the frame. When the endplate is moved relative to the frame in a direction along the longitudinal axis of the frame, the endplate is moved in a direction away from the frame to increase the height of the spacer. A second endplate configured to engage a second bone of the joint can be similarly configured.

Abstract: The invention is directed to an interbody fusion device comprises a load bearing component and a retention component and further comprises two bone screws that pass through the retention device and into the vertebral bodies. When implanted, the construct is flush with the anterior face of the vertebras and provides support and temporary fixation for the ultimate fusion of the vertebral bodies.

Abstract: An intervertebral insert member and an instrument for positioning the insert in a space between vertebral bodies in vivo. The insert member is advanced by the instrument into a prepared site located between adjacent vertebral bodies. Upon reaching the appropriate insertion point, the sleeve is retracted and a pivotal motion is imparted to the insert. The insert member is pivotally attached to the distal end of the delivery instrument such that it can be articulated about a pivot point that is located on the insert member until it is properly positioned. The positioning instrument is then released from the insert member and removed from the space between the vertebral bodies. An adjustment screw is available to expand the surfaces of the insert member by displacement of a wedge member within the insert.

Abstract: For inserting a cage in the intervertebral disk space between two vertebrae, an instrument set includes a guide wire with a plurality of dilators that can be pushed over the guide wire and one over another, with a working sleeve and with a cage, in which the working sleeve is designed in its distal area such that it makes possible the fixation of its distal area in the direction of its extension with angular mobility or variable angular orientability of its proximal end.

Abstract: An implant includes a body that defines an axis and has an interior. A counter element is disposed on the body to releasably fix a manipulating tool thereto. The counter element has at least two undercuts spaced apart relative to the axis of the body and each has a respective holding surface oriented towards the interior of the body. A bearing surface is on the counter element to rotationally fix the implant relative to the manipulating tool. The bearing surface is oriented non-coaxially with the axis of the body.

Abstract: A prosthetic feeding device and a multi-position prosthetic device are provided herein. In one embodiment, the prosthetic feeding device includes: (1) a multiple position rotator having (1A) a main body having a shaft tunnel and a rotation director, (1B) a rotating body having a pivot shaft and a head with a device receptor, wherein the rotation director is located within the main body and positioned to permit rotation of the pivot shaft within the shaft tunnel in either a clockwise or counter clockwise direction around a longitudinal axis of the main body, and (1C) a cap screw mechanically coupled to the pivot shaft to position the pivot shaft in the shaft tunnel; and (2) an eating utensil mechanically coupled to the head via the device receptor.

Abstract: A blade-type prosthesis assembly includes a blade body extending between a blade bottom and a blade top. The blade top is securable to a socket for a limb and the blade bottom defines a convex surface formed by at least one edge of the blade bottom curving toward the blade top. The prosthesis assembly further includes a base plate. The base plate includes a base plate top surface securable to the blade bottom, a base plate bottom surface opposing the base plate top surface, and a plurality of ground-engaging elements extending from the base plate bottom surface.

Abstract: Blade-type prosthesis assemblies include a socket securable to a wearer of the prosthesis assembly and a blade securable to the socket. The blade has a blade body extending between a blade bottom and a blade top. The assembly further includes a base plate securable to the blade bottom. The base plate includes a shroud retainer element. The assembly further comprises a blade shroud covering at least a portion of the blade body and securable to the shroud retainer element and at least one of the socket and the blade body.

Abstract: A garment for retaining a prosthesis assembly includes a sleeve configured to encase at least a portion of a limb and at least a portion of a prosthesis for the limb. The garment further includes tension bands extending along the sleeve and configured to secure the prosthesis to the limb. Another exemplary garment is a body suit including a pant leg configured to encase at least a portion of a leg and at least a portion of a leg prosthesis. The body suit further includes tension bands integrally extending from the pant leg along a torso portion of the body suit and around a shoulder portion of the body suit and configured to secure the leg prosthesis to the leg.

Abstract: The present disclosure relates to a radial volume adjustment device. The device includes a connection plate. The device further includes a socket wall comprising a plurality of socket wall components, at least one of the plurality of socket wall components comprising a channel, the channel forming an arcuate path curving towards a center of the connection plate. The device further includes at least one attachment member configured to couple with the connection plate and pass through the at least one channel such that the at least one socket wall component may move in a path defined by the at least one attachment member and the channel. The movement of the at least one attachment member causes a volume defined by the socket wall to change.

Abstract: A drug delivery device (10) includes expandable element (12) formed of a braided structure having a body portion (16) and first and second end cones (18, 20). The end cones are attached at their necks (22, 24) to a catheter assembly (14). The expandable element (12) can expand to a vessel contacting configuration, in which the body portion (16) contacts the vessel wall. Bioactive agent (28) covers at least the outer surface of the body portion (16) such that bioactive material can be administered to a vessel wall. The end cones (18, 20) have an open structure allowing unrestricted passage of blood through the device (10) in the deployed configuration, such that blood flow can be maintained during the administration of bioactive agent (28) from the device (10). The expandable element (12) can be radially contracted by extending it in the longitudinal direction, both for deployment endoluminally to the treatment site and also for retrieval following the administration of the bioactive material.

Abstract: A biodegradable stent prosthesis formed from a degradable polymeric material, having a plurality of luminal, abluminal, and side surfaces, where at least some of the abluminal surfaces are concave and optionally the side surfaces are convex.

Abstract: A biodegradable stent prosthesis formed from a degradable material, having a plurality of luminal, abluminal, and side surface regions, wherein a surface portion extending between the abluminal and luminal surface region of at least some structural elements is convex or bulbous and optionally, where at least some of the abluminal surface regions may be concave.

Abstract: A biodegradable stent prosthesis formed from a degradable material, having a plurality of luminal, abluminal, and side surface regions, wherein a surface portion extending between the abluminal and luminal surface region of at least some structural elements is convex.

Abstract: Stents are provided with scaffold structures which have low exposures when implanted in arteries and other blood vessels and lumens. The cross-sectional dimensions, materials, and patterns are controlled to provide sufficient strength and coverage while maintaining the low exposure.

Abstract: Radially expandable implantable medical devices, such as stents, with locking elements are disclosed.

Abstract: A convertible nephroureteral catheter is used in the treatment of urinary system complications, particularly on the need for a single surgically delivered device to treat patients who must be seen by an interventional radiologist (IR). In many current procedures, patients need to return to the operating room to remove a previously delivered nephroureteral catheter to exchange this catheter with a fully implanted ureteral stent delivered though the same access site at the flank. The present convertible nephroureteral catheter reduces the need to return for a second surgical procedure. Two weeks after initial implantation, the proximal portion of the convertible nephroureteral catheter extending out from the body may simply be removed. A simple action at the catheter hub allows this proximal portion to be removed, leaving behind the implanted ureteral stent within the patient's urinary system. Other medical procedures, devices, and technologies may benefit from the described convertible catheter.

Abstract: A delivery system for endoluminal delivery of an expandable device comprising a catheter having a proximal end and an opposite distal end configured to support an expandable device, a primary sheath having a delivery position in which the primary sheath constrains the expandable device toward a collapsed configuration suitable for endoluminal delivery, and a handle having an actuator for axially displacing the primary sheath from the delivery position, wherein the handle includes a knob for operating one or more functions of the handle which is initially hidden to prevent use by a user and then revealed as a result of displacement of the primary sheath from delivery position so as to allow subsequent actuation of the knob by the user.

Abstract: The present disclosure includes an endoprosthesis delivery system comprising an elongate member, such as a catheter, an endoprosthesis, a covering member disposed about the endoprosthesis, a tip, and an end cap. The tip and end cap can be integral to each other. The covering member can extend beyond the distal end of the endoprosthesis and onto the end cap. The end cap can comprise a tapered profile, which may assist in retraction of the catheter tip and end cap into an outer sheath. The end cap can further comprise one or more fins.

Abstract: A delivery system for delivering and deploying stents with proximal and distal apices includes a guidewire catheter, a nose cone assembly, a proximal capture portion and a stent graft with proximal and distal stents. The nose cone assembly is at the distal end of the guidewire catheter and includes a nose cone and a distal capture portion. The proximal capture portion is proximal to the distal capture portion of the nose cone assembly. The proximal stent is releasably secured to the distal capture portion and the distal stent is releasably secured to the proximal capture portion. The stent graft can be deployed by releasing the proximal stent and the distal stent from proximal and distal capture portions of the delivery system.

Abstract: A device to release from an implant bed in the device a self-expanding implant by pulling back proximally, the length of the implant, a rolling membrane with an inner sleeve that extends distally to the distal end of the implant and an outer sleeve that extends proximally, from the distal end of the inner sleeve, the outer sleeve, during said release, pulling the distal end of the inner sleeve back proximally over the abluminal surface of the remainder of the inner sleeve, proximal of its distal end, the device having a slitter, that is caused to move proximally contemporaneously with the outer sleeve, to slit the inner sleeve progressively, starting at a distal point in the inner sleeve, and progressing proximally along the length of the inner sleeve.

Abstract: A knee assistive device for cushioning and protecting a user is provided. The device comprises a concave base having an inner surface, an outer surface, a front end, a first side, a second side, and a rear end. A side wall extends upward from the base. A knee well is formed in the inner surface of the base adjacent the front end. A foot well is formed in the inner surface of the base adjacent the knee well of the base with the foot well being separate and distinct from the knee well and extending to a point below the knee well. A cushioned pad is positioned within the knee well. Upon positioning of the knees within the knee well and the feet within the foot well, the user rocks back and forth on the base while the knees, calves, ankles, and feet of the user are cushioned and protected.

Abstract: An ankle brace has a stirrup with a flat bottom portion and a first and second upright leg. Each of the first and second upright legs has an upper end and a lower end, the upper end having a circular opening therethrough and the lower end attached to the flat bottom portion. First and second pivot legs, each having a circular opening therethrough, are removeably and rotatably connected to the first and second upright legs respectively. First and second leg extensions are removeably connected to the first and second pivot legs, respectively. When connected, the circular openings in the pivot legs overlap the respective circular openings in the upright legs, and each pivot leg is rotatable about an axis through and perpendicular to the pivot leg circular opening. The circular openings in the first and second upright legs are positioned and sufficiently large to allow at least a portion of the malleolus bone of an ankle to protrude therethrough.

Abstract: A rehabilitation footwear comprises a shoe body, multiple fasteners, a lower back guard pad, an upper back guard pad, a lower front guard pad, an upper front guard pad, and two supporting frames. A full-cover rehabilitation footwear can be built up by combining the shoe body, the lower back guard pad, the upper back guard pad, the lower front guard pad, and the upper front guard pad together with the multiple fasteners. A supporting-type rehabilitation footwear can be built up by combining the shoe body, the lower back guard pad, the middle back guard pad, the lower front guard pad, and the middle front guard pad together with the multiple fasteners. A frame-type rehabilitation footwear can be built up by combining the shoe body and the two supporting frames together with the multiple fasteners. An adjustable rehabilitation footwear is provided.