Abstract: [Object] To provide a solid fuel which comprises a binder, a form retaining agent and a vegetable oil-containing substance in a balanced manner, has a stable calorific value and suppresses the production of carbon dioxide. [Solution] A solid fuel formed from a mixture of a binder, a form retaining agent and a vegetable oil-containing substance, wherein the amount of the binder is 1 to 85 parts by weight, the amount of the form retaining agent is 1 to 55 parts by weight, and the amount of the vegetable oil-containing substance is 10 to 85 parts by weight based on 100 parts by weight of the mixture, and the mixture is molded.

Abstract: A fire kindler (FIGS. 1,2 and 3) comprised of a geometrically shaped slab configuration of combustible material which operates in vertical positioning to present common lower crest (20) and a structural continuation of symmetric communal acclivity with surfaces (16),(10), and (12) which all culminate at top surface (14). Body of fire kindler (8) having apertures, (18A),(18B), and (18C) of generally horizontal and variable plurality, passing completely therethrough. Other embodiments utilizing lessor, greater, or no apertures at all.

Abstract: A friction modifier composition for reducing friction in a lubricant comprising a fatty acid sorbitan ester that is solid or semi-solid. The fatty acid sorbitan ester is capable of being released into a lubricant at a rate of less than or equal to 0.15 grams per minute.

Abstract: A composition for prevention or reduction of fatigue damage, especially trench formation or micropitting, of the surfaces of drive elements, is provided that comprises 0.1 to 40% by weight of surface-modified nanoparticles, and 99.9 to 60% by weight of a carrier material suitable for application to the drive element surfaces.

Abstract: A lubricating oil comprising a major amount of a base oil and a minor amount of an additive package, and the additive package comprises at least one friction modifier selected from compounds of the formulae II, III and IV, and carboxylate salts thereof: wherein R is a linear or branched, saturated, unsaturated, or partially saturated hydrocarbyl having about 8 to about 28 carbon atoms, n is 0 or 1; and the carboxylate salts have a cation that is an alkali metal, alkaline earth metal, group IIB metal, or ammonium cation; and a dispersant and/or a detergent wherein said lubricating oil comprises at total of at least 5 wt. % of the dispersant and/or the detergent. Methods of using the engine oil to improve thin film and/or boundary layer friction in an engine are also provided.

Abstract: A wear and/or friction reducing additive for a lubricating fluid in which the additive is a combination of a moderately hydrophilic single-phase compound and an anti-wear and/or anti-friction aqueous salt solution. The aqueous salt solution produces a coating on boundary layer surfaces. The lubricating fluid can be an emulsion-free hydrophobic oil, hydraulic fluid, antifreeze, or water. Preferably, the moderately hydrophilic single-phase compound is sulfonated castor oil and the aqueous salt solution additionally contains boric acid and zinc oxide. The emulsions produced by the aqueous salt solutions, the moderately hydrophilic single-phase compounds, or the combination thereof provide targeted boundary layer organizers that significantly enhance the anti-wear and/or anti-friction properties of the base lubricant by decreasing wear and/or friction of sliding and/or rolling surfaces at boundary layers.

Abstract: Provided is a lubricant composition for a full transmission system, comprising: (A) at least an ashless dispersant; (B) at least a friction modifier; (C) at least a phosphorus-containing antiwear agent; (D) at least an antirust additive; (E) at least a sulfur-containing extreme-pressure additive; (F) at least a metal deactivation additive; (G) at least a viscosity index improver; (H) at least a pour-point depressant; and (I) at least a highly refined mineral oil with high viscosity index, or polyolefin synthetic oil, or ester synthetic oil, or any combination of the above components. The lubricant composition has excellent cleaning dispersity, frictional characteristic, antirust and anti-corrosive properties and extreme pressure abrasion resistance, meets US force standard MIL-PRF-2105E, and can be used for lubrication in various vehicle transmission systems.

Abstract: The purpose of the present invention is to provide an extreme pressure agent which does not contain any metal element or the like and is highly safe but which exhibits performance equivalent to those of conventional extreme pressure agents each containing a metal element or the like when used in lubrication purposes. This extreme pressure agent comprises a copolymer (A) which comprises an alkyl acrylate (a) represented by general formula (1) and a hydroxyalkyl acrylate (b) represented by general formula (2) as the essential constituent monomers, and is characterized in that the reaction ratio of the component (a) to the component (b) (i.e., (a)/(b)) is 50/50 to 80/20 (by mole) and the copolymer (A) has a weight average molecular weight of 40,000-150,000. (In formula (1), R1 represents an alkyl group having 10-18 carbon atoms.) (In formula (2), R2 represents an alkylene group having 2-4 carbon atoms.

Abstract: A polyalkylene glycol comprising: a random copolymer comprising units derived from EO and units derived from PO initiated with polytetrahydrofuran; wherein the polyalkylene glycol has a pour point of less than or equal to ?30° C. as measured using ASTM D97 and a traction value of less than 0.0165 at a contact pressure of 1.25 GPa, speed=2 m/s, SRR of 100% and temperature of 80° C. is provided. Also provided are lubricant compositions containing such polyalkylene glycol.

Abstract: The lubricating oil composition of the invention comprises a lubricant base oil, a 3,4,5-trihydroxybenzoic acid ester at 5-5000 ppm by mass, and a phosphorus compound at 0.001-10.0% by mass, based on the total mass of the lubricating oil composition. The lubricating oil composition of the invention significantly lowers wear and exhibits a stable low frictional coefficient, while having a high rust-preventing effect for iron-based sliding sections. The lubricating oil composition of the invention is therefore suitable for prolonged use, and exhibits a notable effect for energy savings as well due to its stable low frictional coefficient property.

Abstract: Provided is a method for producing a fatty acid composition having a low content of saturated fatty acid easily and with a high yield from a decomposed fatty acid composition containing monoacylglycerol. The method for producing a fatty acid composition having the content of saturated fatty acid of 8% by mass or less, comprising the following steps (1) to (3): (1) obtaining a fatty acid mixture by adjusting the component ratio of a decomposed fatty acid composition obtained by hydrolyzing a fat or oil so that the content of fatty acid is from 80 to 96% by mass, the content of monoacylglycerol is from 0.3 to 8% by mass, the content of diacylglycerol is from 1 to 12% by mass, and the mass ratio of diacylglycerol to monoacylglycerol [ (DAG)/(MAG)] is from 0.5 to 40; (2) cooling the fatty acid mixture obtained in step (1) to a temperature within the range from the temperature 2° C. lower than the cloud point of the fatty acid mixture to the temperature 13° C.

Abstract: The present invention relates to the field of perfumery. More particularly, it provides a perfuming composition capable of prolonging the release of a perfuming component into the surrounding environment when applied on a body surface such as skin or hair. The composition comprises Neopentyl Glycol Diethylhexanoate as a fragrance evaporation modulator in the presence of high amounts of ethanol. The invention also relates to consumer articles containing such compositions. It finally provides methods for the perfuming of a body surface and a method for increasing the long-lastingness of a perfuming component using these compositions.

Abstract: The present disclosure provides a flower essential oil extraction method. The flower essential oil extraction method includes (a) placing flowers in a high-pressure treatment tank; (b) introducing pressurized liquid medium into the high-pressure-treatment tank so as to reach a predetermined pressure, wherein the pressure is maintained for a predetermined period of time at a predetermined temperature, then the pressure is reduced to atmospheric pressure; and (c) placing the flowers subjected to high-pressure treatment in an extraction tank, wherein flowers are extracted with a low-polarity solvent to obtain an extract. By using the flower essential oil extraction method of the present disclosure, the flowers do not need to be subjected to a dehydration process, thus the energy cost is reduced, and more ingredients can be retained.

Abstract: A composition for treating a hard surface. The composition has: (a) at least one adhesion promoter; (b) at least one surfactant selected from the group consisting of: anionic, non-ionic, cationic, amphoteric, zwitterionic, and combinations thereof; (c) mineral oil; (d) a blend of linear primary alcohols, wherein each alcohol of said blend includes a carbon chain containing 9 to 17 carbons or an ethoxylated blend thereof; (e) water; (f) optionally, at least one solvent; and wherein the composition is self-adhering upon application to a surface to be treated, and wherein the composition provides a wet film to said surface when water passes over said composition and surface.

Abstract: Methods of cleaning a medical device are provided via exposing the medical device to a compressed CO2-based mixture. The compressed CO2-based mixture includes carbon dioxide, a surfactant, and water in the form of water-in-CO2 microemulsions. In one particular embodiment, the ratio of water-to-surfactant mixed together in the CO2 has a range of about 5-100 molecules of water per molecule of surfactant (e.g., about 5-30 molecules of water per molecule of surfactant).

Abstract: A cell picking support device, a display device and a culture container that can enhance work efficiency. An adapter fixes a well plate that holds cells cultured in a cell culture observation device. A control unit reads culture observation information that includes cell information and coordinate information, from a memory card that is fitted to an external memory I/F. A display unit is provided on a placing surface side of the well plate that is fixed by the adapter, and in response to control by the control unit, displays the cell information, read from the memory card, at display positions corresponding to positions on the bottom face of the well plate, as specified by the coordinate information. Embodiments can be used, for instance, as a cell picking support device that supports a picking operation that is performed in a clean bench.

Abstract: The device for the transfer of a medium comprises a magazine having two main faces (17) of which one is adapted to cooperate with a container and a lateral face (18) extending between said main faces (17) as well as at least one sliding valve (3) housed in a cavity of said magazine (2) and in which there is formed a transfer duct (59) for said medium which issues on said face (17) adapted to cooperate with said container, said valve (3) having a closed position in which it sealingly isolates said duct (59) from said container and an open position in which said duct (59) is placed in communication with said container; said valve (3) comprising a valve member (40), an isolation sleeve (41) surrounding at least partially said valve member (40) as well as spring means (58) adapted to be compressed by said valve member (40) when said valve (3) is in its open position.

Abstract: A portable apparatus useful for collection and processing of human biological material containing adipose, such as extracted during a lipoplasty procedure to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with a containment volume with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. Inlet and suction ports provide access to the tissue retention volume and filtrate volume, respectively, and an extraction port provides versatile access for removal of target processed concentrate material or fat graft material, which access may be via a lumen through a rotatable mixer shaft. Access ports may be configured for access only from above the container. The apparatus may include a tissue collector disposed in the disuse retention volume to engage and collect collagen or other stringy tissue.

Abstract: A method of fractionating biomass, by permeability conditioning biomass suspended in a pH adjusted solution of at least one water-based polar solvent to form a conditioned biomass, intimately contacting the pH adjusted solution with at least one non-polar solvent, partitioning to obtain an non-polar solvent solution and a polar biomass solution, and recovering cell and cell derived products from the non-polar solvent solution and polar biomass solution. Products recovered from the above method. A method of operating a renewable and sustainable plant for growing and processing algae.

Abstract: In some embodiments, a system may reduce contaminants in water. A system may include a biofilm in a container. The biofilm may be formed from one or more bacteria coupled to one or more substrates. The bacteria may be selected to maximize the reduction of contaminants in water. The system may include one or more bacteria generators to provide bacteria to the biofilm and/or one or more air sources to provide an air bubble stream to the container and/or the bacteria generator. In some embodiments, bacteria may be preserved in a starvation phase. Bacteria may be incubated until they reach a starvation phase. The bacteria may then be preserved as beads or immobilized on a substrate. The preserved bacteria may be used in a system for the reduction of contaminants in water.

Abstract: The present invention relates to multi-coated lactic acid bacteria coated with a multi-coating layer forming bacterial clusters and including protein, polysaccharide, and edible oil/fat component, and a preparing method thereof. The multi-coated lactic acid bacteria according to the present invention may achieve an improved acid resistance, a bile resistance, and an accelerated test stability, may have a low moisture content to be particularly stable against a moisture variation, and thus may be appropriately used to prepare various products including lactic acid bacteria.

Abstract: The present invention provides a cell adhesion matrix having poly(vinyl alcohol) chains crosslinked via carboxy phenyl boronic acid crosslinkers. The cell adhesion matrix can also include a molecular recognition element bound to the poly(vinyl alcohol) chains via a carboxy phenyl boronic acid group, as well as including cells. The present invention also provides a method for making and de-gelling the cell adhesion matrix.

Abstract: The present invention generally relates to compositions and methods of delivering living cells in a dry mode, wherein the compositions include a surface layer disposed on the outer surface of the composition that is permeable to carbon dioxide and oxygen. The compositions may be used to deliver living cells to a delivery point without the use of expensive refrigerants such as dry ice or liquid nitrogen.

Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.

Abstract: The present invention relates to infectious bronchitis (IB) viruses derived from a recently identified genotype of IB virus known as IB-QX, or from viruses that are genetically related to IB-QX, herein referred to as IB-QX-like viruses. The IB viruses of the invention may be live and attenuated or inactivated. Live, attenuated IB viruses of the invention may be produced by serial passaging of an IB-QX-like virus. The IB viruses of the invention are useful for, inter alia, vaccines against IB-QX and IB-QX-like viruses. Heretofore, known vaccine strains of IB viruses have proven insufficient to protect against infectious bronchitis caused by IB-QX and IB-QX-like viruses.

Abstract: The present disclosure relates to engineered ketoreductase polypeptides and uses thereof for the preparation of ?-chloroalcohols from ?-chloroketones. Also provided are polynucleotides encoding the engineered ketoreductase polypeptides and host cells capable of expressing the engineered ketoreductase polypeptides.

Abstract: The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.

Abstract: The present invention relates to the use of Archease proteins as RNA ligase enhancer, methods of ligating RNA molecules, kits for these methods and uses and transgenic cells.

Abstract: The invention relates to an improved vaccine against pertussis wherein mutants of Bordetella pertussis having a modified LPS molecule or the obtainable LPS molecules are used. These mutants or the obtainable LPS molecules may further be used as an adjuvant.

Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.

Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.

Abstract: Glutamine phenylpyruvate transaminase (GPT) proteins, nucleic acid molecules encoding GPT proteins, and uses thereof are disclosed. Provided herein are various GPT proteins and GPT gene coding sequences isolated from a number of plant species. As disclosed herein, GPT proteins share remarkable structural similarity within plant species, and are active in catalyzing the synthesis of 2-hydroxy-5-oxoproline (2-oxoglutaramate), a powerful signal metabolite which regulates the function of a large number of genes involved in the photosynthesis apparatus, carbon fixation and nitrogen metabolism.

Abstract: Provided are compositions comprising recombinant DNA polymerases that include amino acid substitutions, insertions, deletions, and/or exogenous features that confer modified properties upon the polymerase for enhanced single molecule sequencing. Such properties include increased resistance to photodamage, and can also include enhanced metal ion coordination, reduced exonuclease activity, reduced reaction rates at one or more steps of the polymerase kinetic cycle, decreased branching fraction, altered cofactor selectivity, increased yield, increased thermostability, increased accuracy, increased speed, increased readlength, and the like. Also provided are nucleic acids which encode the polymerases with the aforementioned phenotypes, as well as methods of using such polymerases to make a DNA or to sequence a DNA template.

Abstract: Provided are novel ?-neoagarobiose hydrolase and a method for obtaining a monosaccharide using the same.

Abstract: A preparation method conducive to enhancing enzymatic activity of cellulase includes the steps of preparing a first inducer, preparing preculture hyphae, producing enzymes by a single strain, feeding a second inducer, and producing enzymes by co-culture strains. Main ingredients of the first inducer and the second inducer are cellulose and lactose, respectively. The enzymatic activity of the cellulase produced is enhanced by induction of cellulose and lactose and co-culture of Trichoderma and Aspergillus.

Abstract: The present invention relates to polypeptides with xylanase activity and uses thereof. The present invention also relates to method of modifying polypeptides with xylanase activity to affect, preferably to increase, xylanase activity and/or bran solubility.

Abstract: The specification discloses Clostridial toxins or Clostridial toxin chimeras comprising an inactivation cleavage site, polynucleotide molecules encoding such toxins or chimeras, compositions comprising such toxins or chimeras, and method of producing such toxins or chimeras.

Abstract: The present invention provides a method of producing ?-santalene by contacting at least one polypeptide with farnesyl phyrophosphate (fpp). In particular, the method may be carried out in vitro or in vivo to produce ?-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing the nucleic acid represent part of the present invention. A non-human host organism and a cell transformed to be used in the method of producing ?-santalene are also part of the present invention.

Abstract: The invention features synthetic materials and methods for inducing cell behavior. Matrix materials induce cell differentiation and cell manipulation based on mechanical and physical characteristics of the materials rather than chemical characteristics.

Abstract: Methods for amplification and sequencing of at least one nucleic acid comprising the following steps: (1) forming at least one nucleic acid template comprising the nucleic acid(s) to be amplified or sequenced, wherein said nucleic acid(s) contains at the 5? end an oligonucleotide sequence Y and at the 3? end an oligonucleotide sequence Z and, in addition, the nucleic acid(s) carry at the 5? end a means for attaching the nucleic acid(s) to a solid support; (2) mixing said nucleic acid template(s) with one or more colony primers X, which can hybridize to the oligonucleotide sequence Z and carries at the 5? end a means for attaching the colony primers to a solid support, in the presence of a solid support so that the 5? ends of both the nucleic acid template and the colony primers bind to the solid support; (3) performing one or more nucleic acid amplification reactions on the bound template(s), so that nucleic acid colonies are generated and optionally, performing at least one step of sequence determination of

Abstract: The current invention relates to use of particular nucleic acids for modulating (increasing or decreasing) blood-brain barrier function, and for use of such nucleic acids in treatment of conditions involving blood brain barrier function, including multiple sclerosis, HIV infection, Alzheimer's disease, Parkinson's disease, epilepsy, and so on. Also provided is an assay for identifying drugs useful in modulating blood brain barrier function.

Abstract: The present invention provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a non-coding nucleic acid sequence of the gene.

Abstract: This invention provides UNA oligomers for therapeutics that can be used to target micro-RNAs. The UNA oligomers can be composed of one or more 2?-3?-seco-nucleomonomers and one or more natural or non-natural nucleotide monomers, and can be a single stranded oligomer. Embodiments include UNA oligomers with phosphorothioate or boranophosphate intermonomer linkages. The UNA oligomers can be used to target micro-RNAs to reduce micro-RNA activity.

Abstract: The present invention is directed to novel double-stranded short interfering (siRNA) analogs comprising locked nucleic acid (LNA) monomers. Such compounds induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). The compounds disclosed herein has improved properties compared to non-modified siRNAs and may, accordingly, be useful as therapeutic agents, e.g., in the treatment of various cancer forms. More particularly, the present invention is directed to siRNA analogs comprising a sense strand and an antisense strand, wherein each strand comprises 12-35 nucleotides and wherein the siRNA analogs comprise at least one locked nucleic acid (LNA) monomer.

Abstract: Novel RET fusion molecules and uses are disclosed.

Abstract: Methods for assessing a pathological condition in a subject include measuring one or more markers where a difference is indicative of acute lymphoblastic leukemia (ALL) or a predisposition to ALL, uses and compositions are disclosed.

Abstract: Trifurcate RNA junction domains derived from phi29 pRNA are described that assemble with high affinity and that are stable in vitro and in vivo. Further expansion of trifurcated RNA domains to multiple way junction scaffolds via creative designs enable an array of toolkit to construct nanoparticle architectures with diverse shapes and angles. The scaffolds can be used to form RNA nanoparticles having a wide variety of uses, including promotion of RNA crystallization, creation of RNA aptamer with high affinity to mimic antibody, delivery of therapeutic and/or diagnostic agents such as biologically active RNA-based moieties, including siRNA, ribozymes, aptamers, and others.

Abstract: A host-vector system that uses the RNA-based copy number control mechanism of ColE1-type plasmids for regulating the expression of a marker gene allows for antibiotic-free selection of plasmids and is useful for production of plasmid DNA and recombinant proteins.

Abstract: The invention relates to compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest.

Abstract: The present invention is related to a recombinant host cell, in particular a yeast cell, comprising a dihydroxy-acid dehydratase polypeptide. The invention is also related to a recombinant host cell having increased specific activity of the dihydroxy-acid dehydratase polypeptide as a result of increased expression of the polypeptide, modulation of the Fe—S cluster biosynthesis of the cell, or a combination thereof. The present invention also includes methods of using the host cells, as well as, methods for identifying polypeptides that increase the flux in an Fe—S cluster biosynthesis pathway in a host cell.