Abstract: In an endoscopic fluid passage changeover valve unit, a communication passage is formed in a shaft, the communication passage being opened to a hollow portion of a cylinder portion in an inside opening located on an outer peripheral surface of the shaft, and a seal member is provided at an angular position apart from the inside opening in circumferential directions of the cylinder portion. The shaft and the seal member are rotatable relative to the cylinder portion around a movement axis toward a position where a first upstream-side fluid passage is blocked by the seal member and toward a position where the inside opening of the communication passage faces the first upstream-side fluid passage.

Abstract: An endoscope securing and positioning device is provided for adjusting or maintaining the position of an endoscope. The device allows the medical professional to easily rotate an endoscope or maintain its position without having to maintain a grip on the endoscope.

Abstract: An endoscope with an adjustable viewing direction includes a shaft, an image transmission device for transmitting an image from a distal end of the endoscope to a proximal end of the endoscope, a hermetically tight sheath around the image transmission device, with a light admission window at the distal end of the endoscope, a manipulating device at the proximal end of the endoscope, a swivel actuation device on the manipulating device for manual adjustment of an angle between the viewing direction and a longitudinal axis of the shaft, a magnetic coupling device for magnetically transmitting a force, parallel to the longitudinal axis of the shaft, between the swivel actuation device and a force transmission device inside the hermetically tight sheath, and a rotation actuation device on the manipulating device for manually rotating the viewing direction about the longitudinal axis of the shaft relative to the manipulating device.

Abstract: Methods and apparatuses for space-optimized visualization catheters are provided. Some embodiments utilize complimentary metal-oxide-semi-conductor (“CMOS”) technology integrated into a CMOS camera train holder system that may be a stand-alone component for use with a visualization catheter, such as a baby endoscope, or may be fabricated/extruded as a part of the catheter itself. Some embodiments of apparatuses, methods, and equivalents thereto provide better direct visual feedback to the medical personnel performing the procedure while providing a similarly-sized outer diameter visualization catheter device having an increased space therein for additional lumens and equipment or by reducing the overall outer diameter of the visualization catheter.

Abstract: The present invention concerns an endoscope for minimally invasive surgery, especially for use within a surgical robotic system, which comprises a main support device (4), which basically extends over the entire length of the endoscope from the outside to the interior of the body, and which comprises at its distal end at least one illumination unit (15, 16) and two imaging devices (12a, 13a, 14a, 12b, 13b, 14b; 12c), wherein each of the imaging devices (12a, 13a, 14a, 12b, 13b, 14b; 12c) is basically arranged in such a way that it can be rotated to the outside on the same level as the main support device (4), a trocar (1), by means of which the endoscope can enter the body, and an additional support device (3), which is provided at the trocar (1) and/or the main support device (4), wherein the additional support device (3) comprises at its distal end an additional imaging device (8, 9, 10, 11), which can be rotated from the additional support device (3) to the outside and wherein the additional imaging device

Abstract: A reduced area imaging device is provided for use in medical or dental instruments such as an endoscope. The imaging device is provided in various configurations, and connections between the imaging device elements and a video display may be achieved by wired or wireless connections. A connector assembly located near the imaging device interconnects the imaging device to an image/power cable extending through the endoscope. The connector provides strain relief and stabilization for electrically interconnecting the imager to the cable. The connector also serves as the structure for anchoring the distal ends of steering wires extending through the body of the endoscopic device. The connector includes a strain relief member mounted over a body of the connector. The connector allows a steering wire capability without enlarging the profile of the distal tip of the endoscopic device.

Abstract: A composite anoscope for ano-rectal diagnostic and surgery, wherein the anoscope (2) also comprises an internal component (1), to be inserted therein, and a suitably shorter external component (3), ending with a conic frustum mantle (18), wherein the anoscope (2) is to be inserted. The three components (1, 2, 3) are all conic frustum shaped hollow bodies having circular cross-section. The internal component (1), when inserted in the anoscope (2), forms therewith a single body having a compact and smooth external surface and an ogival tip. The external component (3) is provided close to its mouth with slotted wings (19, 20), to be fixed to the perianal skin for securing the whole composite anoscope during the diagnostic and surgical operations.

Abstract: A speculum includes upper and lower members and a linear support member. The upper member includes an upper blade. The lower member includes a lower blade and a handle portion. The lower blade includes a support structure at a proximal end thereof which extends vertically on the right or left side of the lower blade, and a handle portion extending downwardly from the lower blade and defining a vertical track. The linear support member has a proximal end pivotally connected to the upper blade, a distal end, and an elongated body between the proximal and distal ends. The elongated body slidably engages the vertical track of the handle portion. The linear support member is formed with a hidden slot which slidably receives the support structure of the lower blade.

Abstract: A multifunction health professional tool, having a pair of scissors with a pair of blades and a pair of handles connected by a pair of shanks. The tool also includes a Babinski reflex hammer detachably connected to one of the handles, a Taylor reflex hammer having a first portion connected to one of the handles and a second portion connected to the opposing handle, a slide ruler attached to one of the shanks, and a pupil dilator light attached to one of the shanks.

Abstract: A process for determining a pair of personalized progressive ophthalmic lenses. and a computer program product associated to these processes. Right-handed persons and left-handed persons behave very differently when executing certain near vision tasks, such as writing on a sheet of paper. However, current lens designs do not take into account these behavior differences. The comfort of wearing a pair of ophthalmic lenses can be improved for the wearer for whom the lenses are intended by adapting his near vision according to his handedness.

Abstract: A light source generates light to fixate a gaze of an eye to be examined, while a scanning unit performs main-scanning and sub-scanning on a fundus of the eye to be examined with the light from the light source.

Abstract: A method may involve forming a cross-linked polymer plug over a sensor located on a structure, such that the sensor is covered by the cross-linked polymer plug. The sensor is configured to detect an analyte. The method may involve forming a first polymer layer, which defines a posterior side of an eye-mountable device. Further, the method may involve positioning the structure on the first polymer layer. Still further, the method may involve forming a second polymer layer over the first polymer layer and the structure to provide a partially-fabricated device. The second polymer layer defines an anterior side of the eye-mountable device. The method may also involve soaking the partially-fabricated device in a fluid, such that the cross-linked polymer plug swells out of the partially-fabricated device to leave a channel in the second polymer layer, wherein the sensor is configured to receive the analyte via the channel.

Abstract: A new tomographic image is generated using a reverse image in which at least one portion of a tomographic image of a retina of an eye to be examined is reversed and the tomographic image so that the reverse image is located on a side on which the retinal layer in the tomographic image is in contact with an end of the tomographic image.

Abstract: An image processing apparatus obtains a plurality of moving images of a predetermined site of an eye, specifies a vascular region by using at least one moving image of the plurality of moving images, and measures the sizes of blood cell aggregates in a specific vascular branch in the specified vascular region for each moving image of the plurality of moving images.

Abstract: An ophthalmic system for use in performing angular measurements in relation to a patient's eye. The ophthalmic system can include an optical angular measurement device that can provide angular indicia by, for example, projecting an image of an angular measurement reticle onto a patient's eye or by superimposing an image of an angular measurement reticle onto an image of the patient's eye. The ophthalmic system can include an optical refractive power measurement device for providing desired angular orientations for ocular implants or for incisions. The ophthalmic system can be used, for example, to align a toric intraocular lens to a desired angular orientation.

Abstract: The present technology relates generally to intraocular pressure (“IOP”) monitoring systems and associated devices and methods. In some embodiments, an intraocular pressure monitoring system configured in accordance with the technology comprises an implantable intraocular assembly and an external unit configured to transmit power to and receive data from the intraocular assembly. The intraocular assembly can include an IOP sensing device embedded within a flexible, expandable annular member. The IOP sensing device can include an antenna, a pressure sensor, and a microelectronic device encapsulated by an elastomer.

Abstract: A computer-controlled sensory testing system is disclosed that can be used to further pain research and aid in the clinical diagnosis and treatment of pain syndromes. The system includes actuators to deliver pressure/deformation (strain), auditory, olfactory, and other stimuli to a subject. The system includes software to control the delivery of the stimuli. The system is further operable to receive feedback regarding the stimuli received.

Abstract: A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved.

Abstract: A method and system for measuring psychological stress disclosed. In a first aspect, the method comprises determining R-R intervals from an electrocardiogram (ECG) to calculate a standard deviation of the R-R intervals (SDNN) and determining a stress feature (SF) using the SDNN. In response to reaching a threshold, the method includes performing adaptation to update a probability mass function (PMF). The method includes determining a stress level (SL) using the SF and the updated PMF to continuously measure the psychological stress. In a second aspect, the system comprises a wireless sensor device coupled to a user via at least one electrode, wherein the wireless sensor device includes a processor and a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the processor to carry out the steps of the method.

Abstract: One embodiment of the invention is disclosed, related to a method for associating at least two different medical findings with each other, each of the findings being based on a characteristic area in a different set of images. The location of at least one anatomical landmark in relation to the respective characteristic area is determined in each in each of the different sets of images. Then a reference to the least one anatomical landmark is stored together with the respective finding for each of the at least two findings. Finally, pairs of associated findings based on a comparison of the respective references to the at least one anatomical landmark are identified among the at least two findings.

Abstract: An endoscope system includes: an endoscope with a unit to be inserted into a subject and captures an inside image of the subject by an imaging unit provided in the unit to generate an image signal; an optical apparatus including a measurement probe to be inserted into the subject through the unit; an endoscope unit that switches between observation light of a plurality of wavelengths and outputs the observation light to observe a target object from the unit; a probe unit that outputs measurement light to measure characteristics of the target object via the measurement probe; a light unit that receives return light via the measurement probe, the return light caused by reflection and/or scattering of the measurement light on the target object; and a switching unit that switches a wavelength band of the measurement light to a different wavelength band from the observation light outputted by the endoscope unit.

Abstract: Rotational shape-memory actuators and associated devices, systems, and methods are disclosed. In some embodiments, a rotational shape-memory actuator includes a first anchor, a second anchor, a spring element extending between the first and second anchors, a first shape memory element extending between the first and second anchors, a second shape memory element extending between the first and second anchors, and a communication line wrapped around the first and second shape memory elements. The first and second shape memory elements are configured to transition between a first configuration in which the first and second shape memory elements are twisted together and a second configuration in which the first and second shape memory elements are less twisted together such that transitions of the first and second shape memory elements between the first and second configurations cause the second anchor to rotate with respect to the first anchor.

Abstract: A method of determining a temperature of a patient includes measuring a first temperature of the patient with a temperature device without contacting the patient with the device, and measuring a second temperature of the patient by contacting a measurement site of the patient with the device. The method also includes determining a temperature value indicative of a core temperature of the patient based on the first and second temperatures.

Abstract: A hemodynamic monitor including a processor incorporating software arranged to continuously analyze and process a blood pressure or arterial volume/plethysmographic signal obtained from the subject in order to derive a plurality of complementary parameters throughout the monitoring of the subject. The monitor also incorporates a display arranged to interact with the processor to display images representing the derived plurality of complementary parameters. The images include at least one image representing graphically at least one stress related hemodynamic parameter plotted against time and at least one image representing graphically at least one fluid responsiveness parameter plotted against time.

Abstract: A system collects and stores data from a source at a high resolution and/or a high data rate (“more detailed data”) and sends a low-resolution and/or downsampled version of the data (“less detailed data”) to a remote server via a wireless network. The server automatically analyzes the less detailed data to detect an anomaly, such as an arrhythmia, earthquake or failure of a structural member. A two-tiered analysis scheme is used, where the first tier is less specific than the second tier. If the first tier analysis detects or suspects the anomaly, the server signals the data collector to send more detailed data that corresponds to a time period associated with the anomaly. The more specific second tier analyzes the more detailed data to verify the anomaly. The server may also store the received data and make it available to a user, such as via a graphical or tabular display.

Abstract: The invention provides a system and method for measuring vital signs (e.g. SYS, DIA, SpO2, heart rate, and respiratory rate) and motion (e.g. activity level, posture, degree of motion, and arm height) from a patient. The system features: (i) first and second sensors configured to independently generate time-dependent waveforms indicative of one or more contractile properties of the patient's heart; and (ii) at least three motion-detecting sensors positioned on the forearm, upper arm, and a body location other than the forearm or upper arm of the patient. Each motion-detecting sensor generates at least one time-dependent motion waveform indicative of motion of the location on the patient's body to which it is affixed.

Abstract: In an electronic sphygmomanometer, the thickness of the second connection tube is set to be lower than the thickness of the first connection tube, and therefore, even if error has occurred in the structural dimensions of the pressure sensor air tube, the error can be absorbed as a result of the second connection tube extending/contracting. It is therefore possible to provide an electronic sphygmomanometer that includes, in a structure in which a pressure sensor used in the electronic sphygmomanometer is disposed, a peripheral structure for the pressure sensor that can improve the reliability of blood pressure measurement values.

Abstract: Some embodiments provide a wearable fitness monitoring device including a motion sensor and a photoplethysmographic (PPG) sensor. The PPG sensor includes (i) a periodic light source, (ii) a photo detector, and (iii) circuitry determining a user's heart rate from an output of the photo detector. Some embodiments provide methods for operating a heart rate monitor of a wearable fitness monitoring device to measure one or more characteristics of a heartbeat waveform. Some embodiments provide methods for operating the wearable fitness monitoring device in a low power state when the device determines that the device is not worn by a user. Some embodiments provide methods for operating the wearable fitness monitoring device in a normal power state when the device determines that the device is worn by a user. Some embodiments provide methods for using response characteristics of the user's skin to adjust a gain and/or light emission intensity of the heart rate monitor.

Abstract: Devices, and methods for monitoring cerebro-hemodynamic signals are disclosed. In one aspect, the devices and methods may include receiving at least one signal characterizing a bioimpedance measurement. The at least one signal may be correlated with the timing of a cardiac wave and analyzed to ascertain an extent of an expected characteristic within the signal. The extent of the expected characteristic may be used to provide information for predicting a physiological brain condition. The at least one signal may include two signals, obtained from opposite brain hemispheres, and may be a bioimpedance signal.

Abstract: An electrode interface system for providing a connection between at least one electrode and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the electrode(s) into uterine activity data signals for use by the maternal-fetal monitor. The electrode interface system of the invention preferably includes a signal converter for processing the signals from the electrode(s) into signals similar to those produced by a tocodynometer.

Abstract: An arrhythmia classification system receives cardiac data from an implantable medical device, performs automatic adjudication of each cardiac arrhythmia episode indicated by the cardiac data, and generates episode data representative of information associated with the episode. The episode data include at least an episode classification resulting from the automatic adjudication of the episode and a confidence level in the episode classification. In one embodiment, the episode data further include key features rationalizing the automatic adjudication of the episode.

Abstract: This document provides methods and materials related to the non-invasive measurement of analytes in blood.

Abstract: A method is disclosed for displaying patient ECG data. The method includes receiving ECG data including an ECG waveform; receiving analyzed ECG data including arrhythmic events; generating an indicia of the detected arrhythmic event; and displaying the indicia of the detected arrhythmic event in relation to the ECG waveform at a position associated with a time of the detected arrhythmic event. A system for displaying patient ECG data is also disclosed.

Abstract: A signal processing arrangement 130, a monitoring system 100, a signal processing method, a monitoring method of monitoring uterine contractions of a pregnant woman, and a computer program product are provided. The signal processing arrangement 130 receives an electrophysiological signal 116 representing uterine muscle activity of a pregnant woman at an input 132. A filter 136 generates a filtered electrohysterogram signal from the electrophysiological signal 116. The filter 136 allows the passage of spectral components between 0 and 3 Hz. A window function applicator 138 applies a window function to the filtered electrohysterogram signal to obtain an output waveform 146. The window function defines that samples of a time interval preceding the application of the window function need to be used The output waveform 146 simulates output data of tocodynamometer or an intra-uterine pressure catheter. The output waveform 146 is provided at an output 144 of the signal processing arrangement.

Abstract: A method of sensing an amplitude and a phase of a varying electrical signal representing an impedance of an electrically conductive tissue through which an AC stimulation current is forced may include measuring a first amplitude value of the varying electrical signal corresponding to an arbitrary initial phase offset value and assuming the first amplitude value corresponds to the amplitude and assuming the arbitrary initial phase offset value corresponds to the phase. The method may include measuring a second amplitude value of the varying electrical signal at a phase offset different from the phase. The method may further include comparing the second amplitude value with the amplitude, and updating the amplitude and the phase to correspond to one of a maximum and a minimum amplitude value and to a corresponding phase offset.

Abstract: A method performed at a computer system having one or more processors and memory storing one or more programs for execution by the one or more processors is disclosed. The method includes accessing multiple images of a biological structure, generating an electrical property map of at least a portion of the biological structure in accordance with two or more of the multiple images, and providing at least a subset of the electrical property map.

Abstract: This invention relates generally to the detection of objects, such as stents, within intraluminal images using principal component analysis and/or regional covariance descriptors. In certain aspects, a training set of pre-defined intraluminal images known to contain an object is generated. The principal components of the training set can be calculated in order to form an object space. An unknown input intraluminal image can be obtained and projected onto the object space. From the projection, the object can be detected within the input intraluminal image. In another embodiment, a covariance matrix is formed for each pre-defined intraluminal image known to contain an object. An unknown input intraluminal image is obtained and a covariance matrix is computed for the input intraluminal image. The covariances of the input image and each image of the training set are compared in order to detect the presence of the object within the input intraluminal image.

Abstract: A method includes, while an operator of an elongated probe, having proximal and distal ends, manipulates the proximal end so as to move the distal end within a body of a patient, automatically measuring a cumulative angle of rotation that is applied by the operator to the proximal end. An indication of the cumulative angle of rotation is presented to the operator.

Abstract: A plethysmographic respiration processor is responsive to respiratory effects appearing on a blood volume waveform and the corresponding detected intensity waveform measured with an optical sensor at a blood perfused peripheral tissue site so as to provide a measurement of respiration rate. A preprocessor identifies a windowed pleth corresponding to a physiologically acceptable series of plethysmograph waveform pulses. Multiple processors derive different parameters responsive to particular respiratory effects on the windowed pleth. Decision logic determines a respiration rate based upon at least a portion of these parameters.

Abstract: An apparatus includes a first portion configured to be coupled to a first bony structure and a second portion configured to be coupled between the first portion and a second bony structure. The second bony structure is disposed opposite the first bony structure. The apparatus further includes a transducer coupled between the first portion and the second portion.

Abstract: A sizing gauge (4) is structured to be used with a patient (8) and is structured to enable an identification of a particular patient interface that is most appropriately sized for the patient. The sizing gauge includes a support portion (12) and a sizing portion (16). The sizing portion includes a first gauge element (36) and a plurality of second gauge elements (40A,40B,40C). The first gauge element is disposed on the support portion and is structured to be positioned at a first location on the patient's face. The plurality of second gauge elements are disposed on the support portion and are situated at locations spaced from the first gauge element. The distance between the first gauge element and each second gauge element is representative of a size in one direction (44) of each of at least some of the plurality of patient interfaces. At least one of the plurality of second gauge elements comprises a tactile feature.

Abstract: A system for constructing multiple shells (electronic models) indicative of the geometry and/or volume of a bodily lumen, such as a heart chamber, is configured to collect a plurality of location data points as the electrode is swept within the chamber. Each of the collected data points has an associated measured cardiac phase at which such point was acquired. The system is configured to segregate the collected electrode locations into sets based on the phase. Each set is characterized by a particular, associated phase of its constituent electrode locations. The system is configured to generate, for each set, a respective shell that will represent the chamber at the associated phase. The shells, once constructed, may be used for or in connection with a variety of diagnostic, mapping, and/or therapeutic procedures. The system is also configured to verify that the electrode is in contact with the heart tissue before using the collected data point in the shell construction (e.g.

Abstract: The invention relates to a system and a method for assessment of walking and miming gait in human. The method is preferably based on the fusion of a portable device featuring inertial sensors and several new dedicated signal processing algorithms: the detection of specific temporal events and parameters, 5 optimized fusion and de-drifted integration of inertial signals, automatic and online virtual alignment of sensors module, 3D foot kinematics estimation, a kinematic model for automatic online heel and toe position estimation, and finally the extraction of relevant and clinically meaning-full outcome parameters. Advantageously including at least one wireless inertial module attached to foot, the system provides common spatio-temporal parameters (gait cycle time, stride length, and stride velocity), with the 10 advantage of being able to work in unconstrained condition such as during turning or running.

Abstract: To provide a micropore forming apparatus capable of increasing the amount of interstitial fluid extracted from micropores formed in the skin of a subject. The micropore forming apparatus includes a skin contact part that has a plurality of microneedles for piercing the skin of the subject, and a force exerting part for exerting a force on the skin contact part toward the skin of the subject. The force exerting part is configured so as to exert a force on the microneedles toward the skin at a position at which the microneedles of the skin contact part are to pierce the skin of the subject.

Abstract: There is provided a microneedle bio-sampling apparatus including: an bio-sampling body enabling a microneedle to be inserted into human skin; and a blocking unit installed in the bio-sampling body and preventing the microneedle from moving to the skin again to prevent repeated bio-sampling by the microneedle. Since the microneedle bio-sampling apparatus is configured to prevent repeated bio-sampling of a single-use microneedle, secondary infection to other part of a human body or a different person due to blood, human anatomy, or the like, that may remain in a microneedle after the microneedle is used once otherwise in case of repeated bio-sampling of a microneedle, can be prevented.

Abstract: Solutions for non-invasively monitoring blood metabolite levels of a patient are disclosed. In one embodiment, the method includes: repeatedly measuring a plurality of electromagnetic impedance readings with a sensor array from: an epidermis layer of a patient and one of a dermis layer or a subcutaneous layer of the patient, until a difference between the readings exceeds a threshold; calculating an impedance value representing the difference using an equivalent circuit model and individual adjustment factor data representative of a physiological characteristic of the patient; and determining a blood metabolite level of the patient from the impedance value and a blood metabolite level algorithm, the blood metabolite level algorithm including blood metabolite level data versus electromagnetic impedance data value correspondence of the patient.

Abstract: Disclosed are methods, apparatuses, etc. for providing a visual expression of the performance of one or more blood glucose sensors. In one particular example, a relative comparison of a rate of change sensor blood glucose and a rate of change in reference blood glucose may be expressed in a polar plot or graph. The polar plot or graph may then be generated onto a visual medium.

Abstract: Disclosed herein is a method and apparatus for measuring biomedical data. The method of measuring biomedical data using a biochemical reaction includes determining reaction termination time at which the biochemical reaction has been stabilized based on an average variation in a predetermined period in an early stage of measurement, and obtaining a final measured value by adding a correction value to a value measured at the determined reaction termination time.

Abstract: An implantable product such as an article, device, or system can include analyte and non-analyte containers in parts that can be operated as optical cavities. The product can also include fluidic components such as filter assemblies that control transfer of objects that affect or shift spectrum features or characteristics such as by shifting transmission mode peaks or reflection mode valleys, shifting phase, reducing maxima or contrast, or increasing intermediate intensity width such as full width half maximum (FWHM). Analyte, e.g. glucose molecules, can be predominantly included in a set of objects that transfer more rapidly into the analyte container than other objects, and can have a negligible or zero rate of transfer into the non-analyte container; objects that transfer more rapidly into the non-analyte container can include objects smaller than the analyte or molecules of a set of selected types, including, e.g., sodium chloride.

Abstract: Lancet device including a skin engaging end that includes a lancet opening through which a lancet needle may extend, a movably mounted holding member configured to receive a lancet, and a combined triggering and cocking system structured and arranged to move the holding member to a retracted position during a cocking phase and to cause the holding member to move to an extended position during a triggering phase. A method of puncturing a surface of skin using the lancet device includes disposing the skin engaging end against a user's skin and manually activating the combined triggering and cocking system. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.