Patents Issued in April 14, 2016
  • Publication number: 20160103916
    Abstract: The technology disclosed relates to de-duplicating contextually similar news feed items. In particular, it relates to assembling a set of news feed items from a plurality of electronic sources and preprocessing the set to generate normalized news feed items that share common company-name mentions and token occurrences. The normalized news feed items are used to calculate one or more resemblance measures based on a sequence alignment score and/or a hyperlink score. The sequence alignment score determines contextual similarity between news feed item pairs, arranged as sequences, based on a number of matching elements in the news feed item sequences and a number of edit operations, such as insertion, deletion, and substitution, required to match the news feed item sequences. The hyperlink score determines contextual similarity between news feed item pairs by comparing the respective search results retrieved in response to supplying the news feed item pairs to a search engine.
    Type: Application
    Filed: October 10, 2014
    Publication date: April 14, 2016
    Applicant: SALESFORCE.COM, INC.
    Inventors: Yair Even-Zohar, Elad Tsur
  • Publication number: 20160103917
    Abstract: The technology disclosed relates to presenting important business insights to a sales engineer. In particular, the technology disclosed assembles a set of news feed items for companies of interest to a sales engineer and groups them into topics. It also qualifies some of the news feed items to return or not based on mandatory or prohibited words in the news feed items. Further, it determines a plurality of metric values for each of the returned news feed items that are based on one of a source metric, business metric, company reference metric, social buzz metric, and matched account metric. It then orders the news feed items, based on the determined metric values, with respect to one or more of source reputation, business activity-related vocabulary, company-name mention, social buzz, and correlation with accounts preferred by the sales engineer, and presents the ordered news feed items as business insights about the topics.
    Type: Application
    Filed: October 10, 2014
    Publication date: April 14, 2016
    Applicant: SALESFORCE.COM, INC.
    Inventors: Alon Talmor, Tal Menahem Brown
  • Publication number: 20160103918
    Abstract: One or more processing devices cause display of a graphical user interface (GUI) enabling a user to specify filter criteria for identifying one or more entity definitions, store the filter criteria in association with a service definition in response to user input, apply the filter criteria to identify one or more entity definitions satisfying the filter criteria, and associate the identified one or more entity definitions with the service definition. The service definition represents a service provided by one or more entities each having a representative entity definition comprising information to identify machine data corresponding to the entity.
    Type: Application
    Filed: January 31, 2015
    Publication date: April 14, 2016
    Inventors: Leonid Alekseyev, Brent Boe, Clint Sharp
  • Publication number: 20160103919
    Abstract: The invention relates to methods and systems for social networking based on profile characteristics (e.g., including phenotypic information) and/or genetic sequence information.
    Type: Application
    Filed: April 24, 2015
    Publication date: April 14, 2016
    Inventor: John Boyce
  • Publication number: 20160103920
    Abstract: Data records are searched by use of a taxonomy comprising search terms having associated respective metadata wherein, for each search term, the associated metadata includes a measure of relatedness based on co-occurrences of search terms in at least one data record of a body of data records. A set of one or more search terms is selected and the taxonomy is referred to so as to extend the set of one or more selected search terms by including any different search terms having a significant measure of relatedness in relation to the one or more selected search terms.
    Type: Application
    Filed: May 6, 2015
    Publication date: April 14, 2016
    Inventors: Howard S. LEE, William A. FISCHER, Simon HAMMOND
  • Publication number: 20160103921
    Abstract: Systems and methods for implementing and performing coaching-assisted content delivery and workflows are described. In one example, a goal-based workflow integrates with operations for suggesting and delivering content on behalf of professional users. The operations may be conducted in connection with a subscription or membership to an information service, and various interactions between a client user and a professional user through the information service. In further examples, the information service may track data for the human user, generate suggestions and playlists, manage the accomplishment of goals and logic triggers, and exchange communications, to facilitate the relationship between the professional user and the client user. In other further examples, the information system manages various data values used to provide prompts, reminders, motivators, and other forms of suggested content to the client user.
    Type: Application
    Filed: August 11, 2015
    Publication date: April 14, 2016
    Inventors: Thomas Edwin Brust, Phil Kennedy, Jamal Khan, Jay W. Johnson, Tom Waddell
  • Publication number: 20160103922
    Abstract: A social networking system selects a set of contacts for presentation to a user of the social networking system. A contact is an additional user or a group of users maintained by the social networking system. To select the set of contacts, the social networking system generates scores associated with additional users of the social networking system and groups of users based on interactions between the user and various additional users and between the user and groups of users. Based on the scores associated with additional users and with groups of users, the social networking system selects a set of contacts from the additional users and the groups of users. Information identifying the set of contacts is communicated from the social networking system to a client device for presentation to the user.
    Type: Application
    Filed: October 9, 2014
    Publication date: April 14, 2016
    Inventors: Aleksandar Ilic, Chuang Wu, Peter Henry Martinazzi, Ziqing Mao
  • Publication number: 20160103923
    Abstract: A computer-implemented method and system are described for customizing content displayed to a user on a user device associated with the user. An example method may include receiving interaction data describing interactions by a user with one or more pages presented on a user device of the user, building a tag expression for the user based on the interaction data, the tag expression including a logical expression of tags and Boolean logic operators, and the tags being associated with page items. The method may also include generating a content page with a customized result customized to the user based on the tag expression.
    Type: Application
    Filed: January 28, 2015
    Publication date: April 14, 2016
    Inventors: Paul Derek Thomas, Young-Keun Andrew Lee
  • Publication number: 20160103924
    Abstract: A method and an apparatus for acquiring an information digest, which belong to the field of the Internet. The method includes: acquiring, according to user information of a user and attribute information of each piece of network information, a click-through rate of clicking a keyword corresponding to each piece of network information by the user (110); combining a preset number of keywords having highest click-through rates to form a first keyword set, and sending the first keyword set to a terminal corresponding to the user (102); receiving a second keyword set sent by the terminal, the second keyword set including a keyword selected by the user from the first keyword set (103); and acquiring an information digest of network information corresponding to each keyword in the second keyword set, and sending the information digest to the terminal (104).
    Type: Application
    Filed: December 18, 2015
    Publication date: April 14, 2016
    Inventors: Zhihao ZHENG, Yan ZHAO, Jianjun YANG, Yiguo YANG, Lu HAN, Qiyun SU
  • Publication number: 20160103925
    Abstract: Apparatus for identifying and providing for the retrieval of information relating to an individual, comprises an adhesive layer and a machine readable device secured to said adhesive layer. The machine readable device is encoded with identification information. A first quantity of ink deposited on said adhesive layer is arranged to provide a physiologically perceptible and humanly understandable visual indication of information relating to set individual. The adhesive layer, the machine readable device and said first quantity of ink form an individual identification device. The machine readable device is secured to said adhesive layer further comprises a second quantity of ink deposited on said adhesive layer and arranged to provide a machine readable image.
    Type: Application
    Filed: September 21, 2015
    Publication date: April 14, 2016
    Applicant: CUTANEOUS INFORMATION TECHNOLOGIES, LLC
    Inventors: Peter Costantino, Laurie Costantino, Michael Gilvary, Anthony H. Handal
  • Publication number: 20160103926
    Abstract: A variety of data structures, components, runtime viewers and methods are described for defining, delivering and rendering wrapped packages of cards in a manner that is particularly well suited, but not limited to, display on mobile devices. Each card may selectively include media content, and a palette of application functionality and/or supporting e-commerce related services. The cards of the wrap packages are ideally threaded together into one or more linear sequences, and authored to convey a book-like narrative that unfolds as the cards are sequentially browsed. In addition, the wrap packages are portable objects that are readily distributed, similar to other electronic messages, through e-mail, messaging, social-media, or via a variety of other electronic communication platforms. As a result, wrap packages are consumable, sharable and savable objects.
    Type: Application
    Filed: April 3, 2015
    Publication date: April 14, 2016
    Inventors: Eric H. GREENBERG, Ian McFARLAND, John M. GARRIS, Mark E. ROLSTON, Jared L. FICKLIN, Matthew J. SANTONE, Jon STEVENS
  • Publication number: 20160103927
    Abstract: A device requests a wrap package from a server. The wrap package has an original size and aspect ratio. The device automatically determines a new card size to fit its viewport having the same aspect ratio and renders each card upon its display screen. All spatial relationships between components in each card are maintained in the new card size, preserving the original impression. A server that stores a wrap package resamples at least one image on at least one card before delivering the wrap package to the device. Once the request is received from the device, the server is aware of the type of device, the optimal card size and the resolution of that device. A new size for the image is determined using current card size and optimal card size. The image is resampled to produce a new image having an appropriate size and resolution for the device.
    Type: Application
    Filed: October 2, 2015
    Publication date: April 14, 2016
    Inventors: John M. GARRIS, Jared L. FICKLIN, Ian McFARLAND
  • Publication number: 20160103928
    Abstract: A web editing application provides a user interface for editing a web page on a mobile client device. The web editing application provides templates for user selection, and may allow users to edit web pages while the editing device is offline. The web editing application determines whether a display of the client device is in landscape mode or portrait mode, and arranges certain cells differently based on this determination. The web editing application may further provide cell configuration indicators that indicate cells that are arranged differently in different display modes.
    Type: Application
    Filed: October 8, 2015
    Publication date: April 14, 2016
    Inventors: Ryan J. Glasgow, Vitaly Odemchuk, Benjamin A. Bloch, Daniel Veltri
  • Publication number: 20160103929
    Abstract: A method and apparatus for an automated classification and reset of browser settings is provided. A set of disreputable browser setting values is maintained based on statistics associated with the browser setting values. In response to determining that an attempt is made to set a browser setting to a value in the set of disreputable browser setting values, a notification can be presented to the user. The notification can include options in a set of reputable browser settings.
    Type: Application
    Filed: October 9, 2015
    Publication date: April 14, 2016
    Inventors: Thomas Wespel, Thomas Salomon
  • Publication number: 20160103930
    Abstract: A system and method for generating analytics based on contextual data are presented. The method includes identifying at least one tag for a portion of data; determining at least one topic based on the identified at least one tag, wherein each topic is a descriptive contextual term; continuously monitoring data from a plurality of data sources respective of each topic; and generating, for each topic, an analytic based on the monitored data.
    Type: Application
    Filed: October 1, 2015
    Publication date: April 14, 2016
    Applicant: HARMON.IE R&D LTD.
    Inventor: Roy Sheinfeld
  • Publication number: 20160103931
    Abstract: In the processing of a query while being translated from the SPARQL language to the SQL language, a manner of navigation through the one or more graphs is provided. The plurality of the nodes in the one or more graphs generated from the query is identified. The plurality of the nodes are assigned a priority and arranged in the priority queue based on the assigned priorities. The node with a highest assigned priority is selected each time for execution of the query from the selected node. The one or more graphs are navigated from the selected node to traverse to the one or more nodes connected with the selected node. An access plan element is generated corresponding to the selected nodes and the one or more traversed nodes.
    Type: Application
    Filed: October 9, 2014
    Publication date: April 14, 2016
    Inventor: Rajendran APPAVU
  • Publication number: 20160103932
    Abstract: A method and a system for dynamically modifying at least one element of a User Interface (UI) of a first electronic device are provided. The method includes collating usage information of at least one data source in the first electronic device, categorizing the collated usage information into one or more knowledge clusters, forming a knowledge graph using the one or more knowledge clusters, and dynamically modifying the at least one element of the UI based on the knowledge graph.
    Type: Application
    Filed: February 11, 2015
    Publication date: April 14, 2016
    Inventors: Sailesh Kumar SATHISH, Nirmesh NEEMA, Bhavani Shankar YELESWARAPU, Ravitheja TETALI, Satnam SINGH
  • Publication number: 20160103933
    Abstract: One or more processors receive a dataset that includes a plurality of nodes. One or more processors identify relationships between a plurality of interacting nodes within the dataset. One or more processors determine relationship strength values between a plurality of interacting node pairs within the dataset. One or more processors generate a graphical representation that represents the relationship strength values between the plurality of interacting nodes within the dataset. Interacting node pairs are connected by edges and the edges have a length that correlates with the relationship strength value between the interacting node pairs.
    Type: Application
    Filed: October 14, 2014
    Publication date: April 14, 2016
    Inventor: Raymond S. Glover
  • Publication number: 20160103934
    Abstract: A method for arranging joints to a 3D model is present. The method first obtains a 3D file, and executes a slice process to a 3D model recorded in the 3D file for obtaining a plurality of cross sections. During the slice process, the method determines if differences between each two cross-section areas of two adjoined cross sections is larger than a threshold. If the difference between the two cross-section areas of two adjoined cross sections is larger than the threshold, the method obtains a corresponding joint data from a database, and arranges the joint data into a position between the two adjoined cross sections. The method finally outputs the arranged 3D model to a 3D printer.
    Type: Application
    Filed: January 3, 2015
    Publication date: April 14, 2016
    Inventors: TIEN-I KAO, TING-YU LU
  • Publication number: 20160103935
    Abstract: Tools in a system for the design of customized three-dimensional models of dental restorations for subsequent manufacturing. Dental restorations such as implant abutments, copings, crowns, wax-ups, bridge frameworks. Moreover, a computer-readable medium for implementing such a system on a computer. A system for designing at least one dental restoration, said system including: a display, means for acquiring and displaying a three dimensional dental restoration model of the dental restoration, and means for displaying a plurality of control points, each of the control points corresponding to a respective location on the dental restoration model, and each of said control points enabling manual customization of the dental restoration model.
    Type: Application
    Filed: December 17, 2015
    Publication date: April 14, 2016
    Applicant: 3SHAPE A/S
    Inventors: Rune FISKER, Tais CLAUSEN, Nikolaj DEICHMANN
  • Publication number: 20160103936
    Abstract: A method, apparatus, system, and computer program product provide the ability to design a road intersection in a three-dimensional (3D) modeling and visualization system. Two roads are defined in the system with the second road intersecting the first road. A set of design rules (that define characteristics of use that contribute to a shape of the road intersection) is acquired. Based on the set of rules, a 3D model of the road intersection is directly created. A property of one of the roads is modified. Without additional user input, the 3D model of the road intersection is automatically and dynamically updated based on the modified property and while maintaining conformance with the set of design rules.
    Type: Application
    Filed: October 1, 2015
    Publication date: April 14, 2016
    Applicant: AUTODESK, INC.
    Inventors: Chakravarthy Gavini, Li Huang, Tao Liu, Guang Han, Yabin Xiao, Ming Chong, Wei Huang, Haibo Wang, Christopher Eric Putnam, Qiang Wu
  • Publication number: 20160103937
    Abstract: The disclosed embodiments relate to a representation of a structure/space as a collection of interrelated partitions whereby manipulation of the partitions causes an automated propagation of the manipulation through the other interrelated partitions as a function of the relationships therebetween. Each partition is defined by one or more vertices, the location(s) of which is/are specified either relative to an origin or relative to, i.e. as a function of, or dependent upon, the location of another vertex within the partition (intra-partition) or within another partition (inter-partition). Where the location of a vertex is moved, the change is propagated implicitly to all other vertices whose location is related, i.e. specified as a function of the modified vertex.
    Type: Application
    Filed: December 21, 2015
    Publication date: April 14, 2016
    Inventor: Paul Landes
  • Publication number: 20160103938
    Abstract: Technology is disclosed for use in diamond processing. Diamond parameter information is obtained and information for numerous diamonds can be aggregated into a database. At least one candidate diamond for potential recutting is identified based on processing the received measurement information by applying logic based on selection criteria stored in the memory. A virtual model is then generated of the at least one candidate diamond based, at least in part, on the received measurement information. The virtual model is analyzed by applying recut criteria to determine a parameter indicative of recut potential and this is output for use in selecting diamonds for a recutting operation. By reducing the requirement to transport diamonds to an analysis site, significant energy, processing, and environmental benefits may be achieved.
    Type: Application
    Filed: June 5, 2015
    Publication date: April 14, 2016
    Inventor: Aaron Ariel
  • Publication number: 20160103939
    Abstract: An example embodiment may involve obtaining a model of physical characteristics of a tangible composite laminate. The tangible composite laminate may include at least two plies, and the model may include representations of each respective ply. The example embodiment may also involve identifying a virtual material model of one or more plies of the tangible composite laminate. The virtual material model may be associated with characteristics that match the representations of the one or more plies of the tangible composite laminate. The example embodiment may further involve updating the model by replacing the representations, in the model, of the one or more plies of the tangible composite laminate with the virtual material model. The example embodiment may additionally involve conducting structural analysis of the updated model.
    Type: Application
    Filed: October 10, 2014
    Publication date: April 14, 2016
    Inventors: Goldy Kumar, Vadim Shapiro
  • Publication number: 20160103940
    Abstract: Generating a target layout of an integrated circuit includes providing a source layout comprising one or more source pcells having one or more shapes; providing a set of connectivity constraints for connecting each shape of each source pcell to none, one, or more other components of the integrated circuit; for each shape of each source pcell, determining a corresponding target shape having a contour composed of edges with defined lengths, inserting none, one, or more edges into the contour of the shape, or into the contour of the corresponding target shape, determining a corresponding edge of the corresponding target shape; for each edge, defining an edge length constraint for constraining the edge to have the length of the edge of the corresponding target shape; applying a legalization procedure to the source layout based on the connectivity constraints, the target design constraints, and the edge length constraints.
    Type: Application
    Filed: June 6, 2013
    Publication date: April 14, 2016
    Applicant: FREESCALE SEMICONDUCTOR, INC.
    Inventors: Alexander Leonidovich KERRE, Mikhail Anatolievich SOTNIKOV
  • Publication number: 20160103941
    Abstract: Systems and techniques for alleviating congestion are described. A set of buffer chains that pass through a congested region of the circuit design can be identified. Next, the set of the buffer chains can be removed from the circuit design. A placement blockage in the circuit design can then be created that covers at least a portion of the congested region. Next, the buffer chains that were removed can be reconstructed in the circuit design in the presence of the placement blockage, thereby alleviating congestion. Once the buffer chains have been reconstructed, the placement blockage can be removed from the circuit design. In some embodiments, congestion can be alleviated by spreading out buffer chains based on spreading out center of mass lines corresponding to the buffer chains.
    Type: Application
    Filed: October 9, 2014
    Publication date: April 14, 2016
    Inventor: Philip H. Tai
  • Publication number: 20160103942
    Abstract: A method of designing an integrated circuit, that includes receiving a first list corresponding to at least one circuit component in a layout, generating a condensed layout from the layout and performing an electrostatic discharge (ESD) check of the condensed layout. The condensed layout is generated by a processor. The ESD check is configured to verify compliance with one or more ESD design rules. The condensed layout includes at least one circuit component. The at least one circuit component includes an ESD circuit and an associated ESD current path.
    Type: Application
    Filed: October 9, 2014
    Publication date: April 14, 2016
    Inventors: Wan-Yen LIN, Shu-Yu CHEN, Yu-Ti SU
  • Publication number: 20160103943
    Abstract: Systems, methods, and other embodiments associated with providing a unified tool for performing design constraints generation and verification for circuit designs are described. In one embodiment, the unified tool reads design data and design intent information for a circuit design. The unified tool generates physical flow elements and verification flow elements of the circuit design, together and in dependence on each other, based, at least in part, on the design data and the design intent information.
    Type: Application
    Filed: October 10, 2014
    Publication date: April 14, 2016
    Inventors: Yibin XIA, Dinesh Rajasavari AMIRTHARAJ, Ali VAHIDSAFA, Alan SMITH, Senthilkumar DIRAVIAM, Mohd Jamil MOHD
  • Publication number: 20160103944
    Abstract: A system and method of analyzing signal performance of a hardware system includes dividing a simulation of the hardware system into a chain of blocks, identifying resonant loops between pairs of blocks in the chain of blocks, determining a loop response for each of the identified resonant loops, and determining an impact of each loop response on a performance of the system.
    Type: Application
    Filed: October 10, 2014
    Publication date: April 14, 2016
    Inventor: Richard Joseph Allred
  • Publication number: 20160103945
    Abstract: In one embodiment, a method of generating write data generates write data for a multi charged particle beam writing apparatus. The method includes dividing a polygonal figure included in design data into a plurality of figure segments including trapezoids each having a pair of parallel opposite sides extending in a first direction, the trapezoids being connected in a second direction orthogonal to the first direction such that adjacent trapezoids share the side extending in the first direction as a common side, and generates the write data including position information of a common vertex of a first trapezoid and a second trapezoid next to the first trapezoid expressed by a displacement in the first and second directions from a position of a common vertex of the second trapezoid and a third trapezoid next to the second trapezoid.
    Type: Application
    Filed: July 8, 2015
    Publication date: April 14, 2016
    Applicant: NuFlare Technology, Inc.
    Inventors: Kenichi YASUI, Shigehiro HARA
  • Publication number: 20160103946
    Abstract: Target designs and methods are provided, which relate to periodic structures having elements recurring with a first pitch in a first direction. The elements are periodic with a second pitch along a second direction that is perpendicular to the first direction and are characterized in the second direction by alternating, focus-sensitive and focus-insensitive patterns with the second pitch. In the produced targets, the first pitch may be about the device pitch and the second pitch may be several times larger. The first, focus-insensitive pattern may be produced to yield a first critical dimension and the second, focus-sensitive pattern may be produced to yield a second critical dimension that may be equal to the first critical dimension only when specified focus requirements are satisfied, or provide scatterometry measurements of zeroth as well as first diffraction orders, based on the longer pitch along the perpendicular direction.
    Type: Application
    Filed: December 18, 2015
    Publication date: April 14, 2016
    Inventors: Mohamed El Kodadi, Nuriel Amir, Roie Volkovich, Vladimir Levinski, Yoel Feler, Daniel Kandel, Nadav Gutman, Stilian Pandev, Dzimtry Sanko
  • Publication number: 20160103947
    Abstract: A hardware verification system includes, in part, a multitude of programmable devices and a system clock. The hardware verification system receives a circuit design and generates a variable period clock from the system clock by analyzing propagation delays in different signal paths of the circuit design. The variable period clock has a first period that occurs in each N cycles of the system clock and a second period that occurs in each M cycles of the system clock, in which M>N. The variable period clock is applied to at least one of the programmable devices to verify the circuit design.
    Type: Application
    Filed: December 18, 2015
    Publication date: April 14, 2016
    Inventors: Alexander Rabinovitch, Cedric Alquier
  • Publication number: 20160103948
    Abstract: A method includes generating a plurality of multiple patterning decompositions associated with a layout of an integrated circuit. Each of the plurality of multiple patterning decompositions includes a first pattern associated with a first mask, a second pattern associated with a second mask, the first mask and the second mask being two masks of a multiple patterning mask set, a width value associated with at least one of the first pattern or the second pattern, and a first spacing value between the first pattern and the second pattern. A file is generated comprising a plurality of dielectric constant values associated with the plurality of multiple patterning decompositions that are based on the width values and the first spacing values.
    Type: Application
    Filed: December 21, 2015
    Publication date: April 14, 2016
    Inventors: Chia-Ming HO, C. Y. (Chia-Yi) CHEN, Hsiu-Wen HSUEH, Jun-Fu HUANG, Shao-Heng CHOU
  • Publication number: 20160103949
    Abstract: Systems and methods are presented in which omics data from multiple cell or tissue samples are used to identify pathway elements that are associated with a treatment parameter of the cell or tissue (e.g., resistance towards a specific drug). So identified pathway elements are then modulated in silico in a statistical factor graph model to provide a modified data set that is re-evaluated with respect to the treatment parameter. Such systems and models are particularly useful for recommendation of multi-drug treatments for treatment-nave patients.
    Type: Application
    Filed: May 28, 2014
    Publication date: April 14, 2016
    Inventors: Stephen Charles Benz, Christopher Szeto
  • Publication number: 20160103950
    Abstract: A method and system for displaying genetic and genealogical data includes displaying indicators of related individuals. At least one genetically related individual is identified from a database in response to a genetic input of an inquiring individual. Indicators of the inquiring individual and each of the at least one genetically related individual are displayed. The system includes a computer system having a display device, a processor device, a database and media having computer-executable instructions configured to display indicators of related individuals according to a method. The method includes identifying at least one genetically related individual from a database in response to a genetic input of an inquiring individual and geographically displaying indicators of the inquiring individual and each of the at least one genetically related individual.
    Type: Application
    Filed: August 13, 2015
    Publication date: April 14, 2016
    Inventors: Natalie M. Myres, Scott R. Woodward, Luke A.D. Hutchison
  • Publication number: 20160103951
    Abstract: Techniques for controlling nucleic acid structures include determining, for each junction type, values for parameters indicating ground-state geometry and both translational and rotational stiffness coefficients. Topological design data indicates a number of bases in each helix connected to corresponding junctions. Initial positions of each base are determined by connecting helices to junctions using the ground-state geometry and arbitrary coordinates not confined to lattice coordinates. Misalignment vectors each indicate a difference in coordinates and orientations between initial positions of a pair of bases that are not adjacent in the initial positions but are adjacent or coincident in the design data. Forces and moments at the junctions to reduce misalignment magnitudes are determined based on the translational and rotational stiffness coefficients at each junction.
    Type: Application
    Filed: October 3, 2015
    Publication date: April 14, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Mark Bathe, Keyao Pan, Do-Nyun Kim
  • Publication number: 20160103952
    Abstract: In one aspect, methods are described herein for enhancing one or more nucleic acid interactions. For example, in some embodiments, methods of enhancing one or more steps of polymerase chain reaction (PCR) are described herein. In some embodiments, the optimal temperature cycling protocol for one or more PCR cycles can be determined according to methods described herein.
    Type: Application
    Filed: May 22, 2014
    Publication date: April 14, 2016
    Inventor: Raj CHAKRABARTI
  • Publication number: 20160103953
    Abstract: Short fixed length source sub-sequences are extracted from a collection of source sequences derived from a sample for which the biological signature is to be determined. The extracted short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. Overlaps between the short fixed length source sub-sequences are used to find a chain of overlaps from one or more sub-sequences equivalent to a pre-flanking reference marker sequence to one or more sub-sequences equivalent to a post-flanking reference marker sequence, wherein the reference marker sequences flank a region containing a repetitive sequence region.
    Type: Application
    Filed: October 10, 2014
    Publication date: April 14, 2016
    Inventors: Thomas C. Conway, Kelly L. Wyres
  • Publication number: 20160103954
    Abstract: Short fixed length sub-sequences, defined as reference sub-sequences, are extracted from a collection of reference sequences, and an index is constructed showing which short fixed length reference sub-sequence occurs in which reference sequences. Short fixed length sub-sequences, the same length as the reference sub-sequences and defined as source sub-sequences, are extracted from a collection of source sequences derived from a sample for which the signature is to be determined, and the short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. The presence or absence of source sub-sequences in combination with the index is used to infer the presence or absence of reference sequences from the reference collection.
    Type: Application
    Filed: October 10, 2014
    Publication date: April 14, 2016
    Inventors: Thomas C. Conway, Kelly L. Wyres
  • Publication number: 20160103955
    Abstract: Short fixed length source sub-sequences are extracted from a collection of source sequences derived from a sample for which the biological signature is to be determined. The extracted short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. Overlaps between the short fixed length source sub-sequences are used to find a chain of overlaps from one or more sub-sequences equivalent to a pre-flanking reference marker sequence to one or more sub-sequences equivalent to a post-flanking reference marker sequence, wherein the reference marker sequences flank a region containing a repetitive sequence region.
    Type: Application
    Filed: July 7, 2015
    Publication date: April 14, 2016
    Inventors: Thomas C. Conway, Kelly L. Wyres
  • Publication number: 20160103956
    Abstract: Short fixed length sub-sequences, defined as reference sub-sequences, are extracted from a collection of reference sequences, and an index is constructed showing which short fixed length reference sub-sequence occurs in which reference sequences. Short fixed length sub-sequences, the same length as the reference sub-sequences and defined as source sub-sequences, are extracted from a collection of source sequences derived from a sample for which the signature is to be determined, and the short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. The presence or absence of source sub-sequences in combination with the index is used to infer the presence or absence of reference sequences from the reference collection.
    Type: Application
    Filed: July 7, 2015
    Publication date: April 14, 2016
    Inventors: Thomas C. Conway, Kelly L. Wyres
  • Publication number: 20160103957
    Abstract: Methods, systems, and computer-readable media are disclosed for calculating corrected amplicon coverages. One method includes: mapping a plurality of reads of a plurality of amplicons based on amplified target regions of a sample suspected of having one or more genetic abnormalities to a reference sequence that includes one or more nucleic acid sequences corresponding to the amplified target regions; calculating amplicon coverages and total reads, wherein amplicon coverages is a number of reads mapped to an amplicon, and total reads is a number of mapped reads; and calculating corrected amplicon coverages based on the calculated amplicon coverages and calculated total reads by applying a batch effect correction.
    Type: Application
    Filed: October 9, 2015
    Publication date: April 14, 2016
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: James VEITCH, Yiping ZHAN
  • Publication number: 20160103958
    Abstract: The present disclosure provides a method for filtering sequence clusters during a process of merging a newly generated nucleotide or amino acid sequence with a set of previously clustered sequences. In another aspect, the disclosure provides a method for assigning newly generated nucleotide or amino acid sequences to presumptive species called operational taxonomic units. In yet another embodiment, the sequences are derived from the cytochrome c oxidase I gene.
    Type: Application
    Filed: June 13, 2014
    Publication date: April 14, 2016
    Applicant: University of Guelph
    Inventors: Paul Hebert, Sujeevan Ratnasingham
  • Publication number: 20160103959
    Abstract: Provided herein are methods, systems, and devices for genetic screening. The genetic screening of two or more individuals can be utilized to predict the phenotype of a child from the group of individuals. Also disclosed is prediction of a phenotype of a child from a subset of biological relatives, such as a potential mother and father, before conception. In many instances, the methods, systems and devices herein are utilized to predict the probability of a child developing a rare genetic disease.
    Type: Application
    Filed: December 16, 2015
    Publication date: April 14, 2016
    Applicant: Counsyl, Inc.
    Inventors: Balaji S. Srinivasan, Balaji K. Srinivasan, Eric Evans, Ranji Srinivasan, Kumaranayagam Balakrishnan
  • Publication number: 20160103960
    Abstract: This disclosure describes systems and methods for a graphical interface including a graphical representation of medical data. The graphical interface platform may receive medical data and provide medical safety reporting capabilities including reporting of history data and real-time visual monitoring data. The graphical interface platform may be configured to identify potential problems and corrections to medical devices in operation while a reporting cycle is underway through visual representation of performance metrics.
    Type: Application
    Filed: December 17, 2015
    Publication date: April 14, 2016
    Inventors: James A. Hume, Robert Mayer, Devy Amy Lee, Gabriele Christensen, Candida Arvelo, Timothy L. Ruchti, Tamas Ban, Mohammad M. Khair, Nancy G. Hedlund
  • Publication number: 20160103961
    Abstract: The present disclosure relates to a mobile telecommunication device for use in a medical system comprising a database server. The mobile telecommunication device is configured for receiving via a voice channel interface from a user, a first voice message, the first voice message indicating one or more medical parameter values indicative of a medical status of the user; generating using the first voice message a second message in a first format interpretable by the database server; sending the second message to the database server using an identification address of the database server; receiving from the database server a response message indicating the interpreted message; displaying the received response message on a display device of the mobile telecommunication device; receiving a user command indicating that the medical status indicated in the response message is not corresponding with the medical status indicated in the first voice message.
    Type: Application
    Filed: October 14, 2014
    Publication date: April 14, 2016
    Inventors: Werner Rodorff, Jerry Maynard Kizziar, SR.
  • Publication number: 20160103962
    Abstract: Apparatus for identifying and providing for the retrieval of information relating to an individual, comprises an adhesive layer and a machine readable device secured to said adhesive layer. The machine readable device is encoded with identification information. A first quantity of ink deposited on said adhesive layer is arranged to provide a physiologically perceptible and humanly understandable visual indication of information relating to set individual. The adhesive layer, the machine readable device and said first quantity of ink form an individual identification device. The machine readable device is secured to said adhesive layer further comprises a second quantity of ink deposited on said adhesive layer and arranged to provide a machine readable image.
    Type: Application
    Filed: September 22, 2015
    Publication date: April 14, 2016
    Applicant: CUTANEOUS INFORMATION TECHNOLOGIES, LLC
    Inventors: Peter Costantino, Laurie Costantino, Michael Gilvary, Anthony H. Handal
  • Publication number: 20160103963
    Abstract: Embodiments of the present invention disclose an improved method for smart healthcare management.
    Type: Application
    Filed: October 14, 2015
    Publication date: April 14, 2016
    Inventor: VARUN MISHRA
  • Publication number: 20160103964
    Abstract: Methods and systems for acquiring a machine-readable optical code, decoding the optical code into a patient identifier, and receiving from a database a billing record filled with patient data corresponding to the patient identifier. The method includes reading by a mobile device the machine-readable optical code and decoding the optical code into a patient identifier. The method includes transmitting the patient identifier to a database. The method includes receiving from the database at least partially filled billing record with patient data corresponding to the patient identifier and displaying on the mobile device the at least partially filled billing record. The method includes searching the database using the patient identifier, and retrieving the patient data corresponding to the patient identifier. The method includes at least partially filling a billing record with the patient data, and transmitting the at least partially filled billing record to the mobile device.
    Type: Application
    Filed: October 9, 2015
    Publication date: April 14, 2016
    Inventors: Federico Osorio, Andres Gutierrez Ovalles
  • Publication number: 20160103965
    Abstract: Systems and methods of using collected data to provide business intelligence functionality and/or information are disclosed. In an example, healthcare information system data (such as billing system data) may be extracted or accessed, and transaction data from multiple information systems may be aggregated. In an example, electronic operations for transformation and processing of healthcare transaction data may include receiving healthcare transaction data, creating an aggregate set of healthcare transaction data, evaluating conditions associated with the aggregate set of healthcare transaction data, generating aggregated healthcare transaction information for display, receiving a user-selected indication in response to the display, and transmitting electronic transaction requests to effect transactions resulting from the user-selected indication.
    Type: Application
    Filed: December 16, 2015
    Publication date: April 14, 2016
    Inventors: Kent F. Ivanoff, Vincent Martino, Nikolaus Trotta, David Arnett