Abstract: A photoacoustic imaging method that enables photoacoustic images to be displayed at high speed is provided. The photoacoustic imaging method scans a subject with a light beam, detects acoustic waves generated within the subject due to the scanning of light to obtain acoustic wave detected signals, and generates volume data that represent three dimensional photoacoustic images of the subject based on the acoustic wave detected signals. Photoacoustic projection images projected in the direction of irradiation depth of the light are generated, prior to the volume data being generated and concurrently with the scanning of the light. The photoacoustic projection images are displayed.

Abstract: An X-ray CT apparatus according to an embodiment includes an X-ray detector and a collimator unit. The X-ray detector detects X-rays that have passed through a subject. The collimator unit eliminates scattered radiation from X-rays that are incident on the X-ray detector. The collimator unit includes a plurality of collimator modules, a supporter, and a fixing unit. The plurality of collimator modules each includes a plurality of first collimator plates arranged in a grid along a channel direction and a slice direction that are orthogonal to each other. The supporter supports the collimator modules such that the collimator modules are aligned in a plurality of straight lines along the channel direction and in a plurality of straight lines along the slice direction. The fixing unit is provided to the supporter and fixes positions of the collimator modules in the channel direction and the slice direction.

Abstract: A CT system includes a rotatable gantry having an opening to receive an object to be scanned, an x-ray source configured to project an x-ray beam toward the object having a primary intensity, a detector configured to detect high frequency electromagnetic energy passing through the object and output imaging data, and a data acquisition system (DAS) connected to the detector and configured to receive the imaging data. The system also includes a computer programmed to obtain image projection data of the object from the DAS, correct the projection data using a scatter function that is based at least on a known characteristic of the x-ray beam, and generate images using the corrected projection data.

Abstract: Simultaneous dual-isotope positron emission tomography (PET) is used to improve disease evaluation. Two distinct molecular probes are simultaneously provided to the imaging target. One of the probes is labeled with a radionuclide that emits positrons to provide double coincidence events in PET. The other probe is labeled with a radionuclide that emits positrons+prompt gammas to provide triple coincidence events in PET. One of the probes is a metabolic probe, and the other probe is a selective probe that includes a ligand or antibody that is biologically responsive to receptor/antigen status. A PET system is employed that can provide simultaneous double coincidence and triple coincidence PET images. The resulting images provide simultaneous metabolic imaging and receptor/antigen imaging. Applications include disease evaluation, such as cancer staging (e.g., for breast cancer, prostate cancer, etc.).

Abstract: A robotic catheter procedure system includes a bedside system and a workstation. The bedside system includes an actuating mechanism configured to engage and to impart movement to a percutaneous device. The workstation includes a user interface and a control system configured to be operatively coupled to the user interface, the bedside system, and a medical imaging system. The control system is responsive to a first input and to a second input, and the user interface receives the second input from a user. The control system is configured to generate a first control signal to the medical imaging system based on the first input, and the medical imaging system captures at least one image in response to the first control signal. The control system is configured to generate a second control signal to the actuating mechanism based on the second input, and the actuating mechanism causes movement of the percutaneous device in response to the second control signal.

Abstract: An image processing method for the 3D display of a patient's organ in which a surgical instrument is positioned, using a medical imaging system comprising a rotating C-arm able to be positioned in at least two angular positions, the C-arm comprising a radiation source at one of its ends, a detector at the other of its ends arranged facing the radiation source, and a collimator arranged between the radiation source and the detector and defining an illumination zone, characterized in that the collimator is adjusted according to the angular position of the rotating C-arm to determine the illumination zone so that the radiation only passes through a region surrounding the surgical instrument.

Abstract: X-ray imaging systems are provided that include an X-ray source and an X-ray detector. A filtering device is positioned between the X-ray source and the X-ray detector and includes one or more micro-filters each adapted to transition between an X-ray filtering position and an X-ray non-filtering position. A controller is programmed to control operation of the micro-filters.

Abstract: An X-ray imaging system has two types of electronic cassettes and one type of IP cassette. Upon entering a body portion to be imaged, an input and output controller retrieves from an imaging condition table of the IP cassette an imaging condition corresponding to the body portion as a reference imaging condition. An imaging condition calculator multiplies reference exposure time of the reference imaging condition by a sensitivity coefficient of each electronic cassette, to calculate an imaging condition to be applied in using each electronic cassette. An input and output controller displays the imaging conditions of the electronic cassettes and the IP cassette and choice buttons for choosing one of the electronic cassettes and the IP cassette in a list form on a monitor.

Abstract: An X-ray imaging apparatus includes: an X-ray sensor configured to convert an X-ray to an image signal; a battery configured to supply electric power for driving the X-ray sensor; a battery holder configured to detachably hold the battery; a lock mechanism configured to lock the battery in a state in which it is attached to the battery holder; and a lock releasing mechanism configured to release the lock effected by the lock mechanism, wherein the lock releasing mechanism is configured to release the lock by the lock mechanism through at least two operations performed by the operator.

Abstract: One or more techniques and/or apparatuses described herein provide a roller truck comprising non-rotating dampening material that is configured to dampen vibrations and mitigate the transference of vibrations from a rotating gantry to a support frame and vice-versa during rotation of the rotating gantry relative to the support frame. It will be appreciated that two different types of roller trucks, base roller trucks and z-axis roller trucks, are described herein, and the non-rotating dampening material may be inserted into one or both types of roller trucks. While the instant disclosure finds particular application in the context of computed tomography apparatus, the instant disclosure is not intended to be limited to such applications.

Abstract: A method for motion correcting molecular breast imaging (MBI) images includes obtaining a plurality of two-dimensional (2D) images of a breast using a MBI system, selecting a reference image from the plurality of 2D images, selecting a feature of interest in the reference image, determining a location of the feature of interest in the reference image, calculating a correction value based on a difference in the location of the feature of interest in the reference image and a location of the feature of interest in a plurality of non-reference images, and aligning the non-reference 2D images with the reference image based on the calculated correction value.

Abstract: A system and method includes reception of a mask x-ray image of a patient volume, reception of a plurality of sequential x-ray images of the patient volume including a contrast medium, subtraction of the mask x-ray image from each of the plurality of sequential x-ray images to generate a plurality of sequential x-ray difference images, filtering of each of the plurality of sequential x-ray difference images based on one or more filter parameters to generate a plurality of sequential filtered x-ray difference images, combination of each of the plurality of sequential filtered x-ray difference images with a corresponding one of the plurality of sequential x-ray difference images based on a weight to generate a plurality of combined sequential x-ray images, and display of the plurality of combined sequential x-ray images sequentially.

Abstract: An embodiment in accordance with the present invention provides a method for non-invasively determining the functional severity of coronary artery stenosis. The method includes gathering patient-specific data related to concentration of a contrast agent within a coronary artery of a patient using a coronary computed tomography angiography scan (CCTA). The patient-specific data is used to calculate a patient-specific transluminal attenuation gradient for the coronary artery of the patient. The patient specific transluminal attenuation gradient is used to determine an estimate of a coronary flow velocity, pressure gradient, loss coefficient, coronary flow reserve, and/or fractional flow reserve for the patient. Coronary flow velocity, pressure gradient, loss coefficient, coronary flow reserve, and fractional flow reserve can then be used to estimate the functional severity of coronary artery stenosis.

Abstract: A method for correction of movement artifacts in a computed tomography image that is reconstructed from a plurality of computed tomography projection images is provided. Using all projection images of the plurality of computed tomography projection images, an average position of an examination area of an examination object in the reconstructed image volume is determined by a global optimization method. With the aid of the at least one image volume block that is formed from predeterminable projection images, the movement of the examination area of the examination object in the at least one image volume block is estimated by an optimization method. A corresponding device for correction of movement artifacts in a computed tomography image is also provided.

Abstract: The present invention is an apparatus for detection of high-frequency heart sounds for diagnosing heart diseases. One embodiment utilizes an accelerometer-based detector that presents a light load to the chest, is sensitive to the desired high frequency range, and provides a quantitative measurement of the quality of the acquired signal. Two pairs of flexible beams, each having piezoelectric transducers on the upper and lower surfaces are supported by a lightweight mechanical structure. The beams are center-loaded so that they respond to the same mechanical energy and will produce identical electrical signals in the absence of noise. Through additional signal processing means the two signals can provide an estimate of the signal-to-noise ratio of the acquired signal. The two signals can also be combined to further improve the signal-to-noise ratio. The invention is designed to be light weight, sensitive to higher frequencies, and to be relatively immune to noise.

Abstract: An ultrasound diagnostic apparatus to improve picture quality of images by automatically adjusting image parameters, and a control method thereof are provided. The ultrasound diagnostic apparatus includes an image signal processor to perform envelope detection processing on ultrasound image data, and an image parameter processor to calculate a Time Gain Compensation (TGC) parameter from the envelope detection processed ultrasound image data, adjust the envelope detection processed ultrasound image data based on the TGC parameter, and calculate a Dynamic Range (DR) parameter from the envelope detection processed ultrasound image data adjusted based on the TGC parameter to apply the DR parameter to the envelope detection processed ultrasound image data.

Abstract: Ultrasound methods, devices, and systems are described which support a useful compromise in terms of spatial resolution and temporal resolution for capturing motion in tissue structures. Tissue engineering articles, methods, systems, and devices which employ ultrasound to deliver biological agents to selected regions of a tissue scaffold, deliver mechanical stimulation to cells growing in a tissue scaffold, and enhance the perfusion of fluids through tissue scaffolds.

Abstract: Disclosed are embodiments of devices and methods for imaging the inside of a body part, such as a blood vessel. In particular embodiments, a catheter has a chamber within which is a transducer mounted to a pivot mechanism, a motor for turning the transducer, and a coil for providing a pivot force to the transducer. A magnet is attached to the transducer and is receptive of a torque applied by a magnetic field produced by energizing of the coil.

Abstract: An apparatus for performing measurements in an artery includes a Doppler catheter, comprising a Doppler transducer and a wire connected to the Doppler transducer; and an elongated catheter body having a conduit therein for housing the wire of the Doppler catheter. The body has a proximal end and a distal end; wherein the wire is movable in the conduit relative to the catheter body so that the Doppler transducer and the wire are capable of being threaded into said conduit at the proximal end after the distal end of the catheter has been inserted into the artery, until the Doppler transducer emerges outside the conduit at the distal end of said body for performing ultrasound measurements in the artery. Another embodiment employs at least an additional side transducer for measuring the cross-sectional dimension of the artery useful for computing blood flow.

Abstract: A cradle for holding an ultrasound probe includes a base for securing to a stepper-stabilizer, roller-bearings supported on the base, and a probe-holder that rotates on the roller-bearings about a horizontal axis relative to the base. The probe-holder includes a front yoke and a rear yoke, with a yoke retainer supporting the front yoke. A pivot side rail and a lock side rail span rigidly between the front yoke and the rear yoke. A locking knob is captured to the lock side rail to prevent the locking knob from detaching. A latch hinged to the pivot side rail is engaged by the locking knob for securement over the probe. A detent ensures 90-degree alignment of the yoke retainer to the base. The rollers rotatably support the yoke retainer and the rear yoke, and further rotation of the front yoke enables a further adjustment to calibrate the cradle.

Abstract: An ultrasound probe includes a stack including a connecting conductor having conductive patterns and a piezoelectric plate disposed on the connecting conductor. The stack has first dividing slits at predetermined intervals. The first dividing slits divide the stack into transducers separate from one another and arrayed in the scanning direction. The conductive patterns are electrically connected to the transducers. Each of the transducers has a second dividing slit parallel to the first dividing slits. The second dividing slit divides each of the transducers into subelements. The first dividing slits extend through the connecting conductor. The second dividing slits are shallower than the first dividing slits and have bottoms apart from the connecting conductor.

Abstract: Volumetric quantification is provided in medical diagnostic ultrasound. By acquiring both B-mode and color flow data without stitching or acquiring in real-time at tens of volumes a second, more reliable quantification may be provided. Using multiple regions of interest in a volume may allow for more accurate and/or complete flow information, such as averaging flow from different locations in the same structure (e.g., use preservation of mass to acquire multiple measures of the same flow).

Abstract: An ultrasound diagnostic apparatus includes a transducer array having a plurality of transducers arranged in an array, a transmission circuit which supplies an actuation signal to each transducer of the transducer array to transmit an ultrasonic wave toward a subject, a reception circuit which corrects a reception signal output from each transducer having received an ultrasonic echo from the subject in accordance with an angle between a reflection point in the subject and an acoustic radiation surface in each transducer to produce sample data, and an image producer which produces an ultrasound image on the basis of a sound ray signal obtained through phasing addition of sample data produced by the reception circuit.

Abstract: Twinkle artifacts are suppressed in color flow. The color flow data itself, such as temporal decorrelation and spatial variance of the velocity and/or power, is used to identify the twinkle artifact. The aliased or high velocities caused by the twinkle artifact are suppressed, such as by reducing the velocity or by spatial filtering that adapts to the locations of the artifact. The powers caused by the twinkle artifact are suppressed.

Abstract: An ultrasonic diagnosing apparatus includes: a transducer array 1 composed of arrayed transducer elements T1 to T6 for transmitting ultrasound; driving circuits D1A to D6A each provided for transmission channels for driving each of the transducer elements; a transmission trigger generator 2 for generating a trigger pulse for controlling each of the driving circuits; a parallel reception beam former 3 for processing reception signals from the transducer elements; a signal processor 4 for processing an output signal of the parallel reception beam former; and a control unit 5 for controlling the transmission trigger generator, the parallel reception beam former and the signal processor.

Abstract: The present invention relates to a kit for taking biopsies, resections, excisions, and/or autopsies. Moreover, the present invention relates to methods of taking biopsies resections, excisions, and/or autopsies using the kit of the present invention. The kits and methods of the present invention allow for fewer errors, decreased turn around time and/or more rapid processing due to a cassette and specimen numbering system that is simplified and superior over that which has been previously disclosed in the prior art. The kit of the present invention comprises one or more tissue cassettes, and optionally one or more bottles of formalin and optionally, other components.

Abstract: The present disclosure relates to a surgical instrument for sampling molecules in an organ which can be accessed directly or via a surgical portal, including: a device for capturing the molecules, a stylet supporting the capture device, capable of entering the organ, a guide for inserting the stylet into the body as far as the organ, wherein the distal end of the guide is provided with a damping block intended to come to bear upon the organ.

Abstract: A medical device for collecting cells includes an inflatable balloon and a perforated sleeve surrounding the balloon. The sleeve includes a plurality of openings therein for collecting cells when inserted into a body cavity. The balloon and sleeve can be housed in a sheath in a compressed delivery condition for being delivered to a target site for cell collection. The balloon and sleeve can then be inflated to expand into contact with the target site. The openings in the sleeve create a mildly abrasive surface for enhancing cell collection while limiting patient trauma. The balloon and sleeve can be reciprocated back and forth to collect cells from the surface of the body cavity. The balloon and sleeve having the collected cells can then be deflated and retracted from the body cavity.

Abstract: A guide device establishes a guide passage through a guide tube, through which an operative tool can be deployed into an interior body region for use. A steering assembly, in use, deflects or bends the distal end region of the guide tube, so that the operative tool can be placed in a desired orientation with respect to tissue. The steering assembly is desirable configured for single handed operation by the clinician. The steering assembly is also desirably configured to provide a mechanical advantage sufficient to translate relatively small increments of clinician control into relatively larger increments of guide tube deflection. In one arrangement, the steering assembly includes a rack and pinion linkage system. In another arrangement, the steering assembly includes a pivoting lever system.

Abstract: A device and method for intravascular dissection of a body lumen, and particularly a blood vessel wall, is disclosed herein. One aspect of the present technology, for example, is directed toward a tubular elongated member having a lumen therethrough, wherein the elongated member includes a distal region configured to be positioned within a blood vessel wall. The distal region can include an angled distal face having a distal-most edge configured to puncture the vessel wall and a proximal-most edge. The member can include an exit port fluidly coupled to the lumen, and positioned along the distal face between the distal-most edge and the proximal-most edge. A central longitudinal axis of the exit port can be offset from a central longitudinal axis of the elongated member such that the exit port is closer to the distal-most edge than the proximal-most edge.

Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. The vascular puncture wound is sealed by natural blood clot formation.

Abstract: A retractor system includes a retractor blade that is securable to a portion of a patient's anatomy during a surgical procedure. The retractor system includes a manipulator that is releasably securable to the retractor blade for positioning and securing the retractor blade. The retractor system includes a flexible securement arm that movably secures the retractor blade to a frame, wherein a proximal end of the retractor blade is non-rigidly constrained. The securement arm is secured to the retractor blade proximate to one end of the securement arm, and is secured to a retractor frame proximate to another end of the securement arm.

Abstract: A surgical access device includes a housing member, a tubular member, a rotor and a lever. The housing member defines a lumen therethrough and includes a port in fluid communication with the lumen. The tubular member defines a longitudinal axis and a channel therethrough in fluid communication with the lumen of the housing member. The rotor defines a longitudinal passage therethrough and a bore on a sidewall of the rotor. The rotor is rotatably associated with the housing member and is coupled to the tubular member. The lever is translatably mounted on the housing member. Axial translation of the lever causes rotation of the rotor about the longitudinal axis between an open position in which the bore is aligned with the port providing a fluid communication between the port and the tubular member and a closed position in which the side wall of the rotor closes off the port.

Abstract: A medical access sheath including a first member, a second member and a third member. The first member includes a longitudinal length and a channel therethrough. The first member includes a slit along the longitudinal length. The channel is configured to expand from a first cross-sectional size to a larger second cross-sectional size. The slit is configured to enlarge as the channel expands. The second member is connected to the first member proximate the slit. The second member extends across the slit. The second member is configured to expand from first configuration to second configuration. The third member is removably located within the channel. The third member is configured to keep the second member in the first configuration when the third member is located in the channel. The third member is configured to release the second member to the second configuration when the third member is removed from the channel.

Abstract: Provided herein are surgical suturing systems, devices, and methods of using the same. The systems and devices are optionally used in surgeries of the stomach.

Abstract: Bone anchors useful in rotator cuff repair optimize the thread pattern for engaging different types of bone tissues, including harder cortical bone and softer cancellous bone. Bone anchors may include fine threads for engaging cortical bone and coarse threads for engaging cancellous bone. Threads can be made finer by increasing root diameter and surface angle of the threads. The pitches of the fine and coarse threads are kept the same, which allows fine threads to follow the impression created by coarse threads as the anchor is driven into a bone. Threads that engage cortical bone can be multi-fluted and include a first flute that follows the same thread pattern as coarse threads such that first flute follows the groove created by the coarse threads as the bone anchor is driven into a bone. Bone anchors can have a distal non-threaded stabilizing extension at the distal end.

Abstract: A single trigger system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes.

Abstract: Suture constructs and methods for soft tissue to bone repairs. The suture construct is a soft anchor which is self-cinching and has the ability to compress from a first, extended, uncompressed position to a second, folded or compressed position. The soft anchor may have a tubular/sleeve/sheath shape and may be formed essentially of a flexible, soft material such as suture, for example, a loosely braided UHMWPE sheath having a tubular configuration.

Abstract: Embodiments described include devices, systems, and methods for reducing the distance between two locations in tissue. An anchor may reside within the right ventricle in engagement with the septum. A tension member may extend from that anchor through the septum and an exterior wall of the left ventricle to a second anchor disposed along a surface of the heart. Perforating the exterior wall and the septum from an epicardial approach can provide control over the reshaping of the ventricular chamber. Guiding deployment of the implant from along the epicardial access path and another access path into and through the right ventricle provides control over movement of the anchor within the ventricle. The joined epicardial pathway and right atrial pathway allows the tension member to be advanced into the heart through the right atrium and pulled into engagement along the epicardial access path.

Abstract: A method of forming a suture anchor comprising a one piece blank folded to form a body. The body has a floor, a first sidewall extending from one end of the floor and a second sidewall extending from an opposite end of the floor. A recess is defined by the floor, first sidewall and second sidewall. A crossbar extends inwardly from the second sidewall across the recess such that a free end of the crossbar is normally disposed distally of a transverse edge of the body. The crossbar is flexible such that when a distally directed force is applied, the free end of the crossbar is positionable in the recess. The free end of the crossbar is engageable with the transverse edge to limit the proximal motion of the crossbar from a proximally directed force.

Abstract: A suture trimmer having a shaft, a cutting member, an actuating device, and a snare. The shaft has a first end and a second end and bounds a bore extending from the first end toward the second end. The shaft has an opening formed in a side adjacent the first end. The cutting member is slidably disposed within the bore of the shaft and can be moved between a first position and a second position, such that when disposed in the second position the cutting member closes the opening formed in the side of the shaft. The actuating device is in communication with the cutting member and is operable to move the cutting member from the first position to the second position. The snare extends through the opening and out of the bore at the first end of the shaft.

Abstract: Systems, devices and methods to improve safety and efficiency in an operating room comprise providing a suture package that holds new suture needles and needle receptacles for storing used needles. The devices can be safely worn for the surgeon to self-dispense new suture needles in the near surgical field and to secure the used needles into a needle trap or a needle retainer located on his extremity, on his operative instruments or on the surgical drapes. The device may provide automated and/or simplified needle counting both during use and after removal from the surgical field. The device may be configured for ergonomic and efficient use so as to minimize the actions and motions of the surgeon to dispense and secure the needle.

Abstract: A radiation targeting system is provided. The system can include an introducer and an implant. The implant can be disposed within a cannula of the introducer and the implant can include a wire stem and multiple different wire branches each extending outwardly from a proximal portion of the wire stem. A radiation source can then be used to target the implant so that radiation therapy can be delivered to a patient. Optionally, a loader and a trocar can be included with the system.

Abstract: A staple cartridge assembly for use with a surgical stapler. The assembly has a cartridge body having a support portion with a plurality of staple cavities with openings. There is also a plurality of staples, wherein at least a portion of each the staple is removably stored within a the staple cavity. Each the staple is movable between an unfired position and a fired position, and is deformable between an unfired configuration and a fired configuration. The assembly also includes a compressible tissue thickness compensator configured to be captured within the staples. The compressible tissue thickness compensator at least partially covers the staple cavity openings. The compressed tissue thickness compensator is configured to assume different compressed heights within different the staples. The compressible tissue thickness compensator comprising a lyophilized foam having an oxygen generating agent embedded therein.

Abstract: An exemplary surgical apparatus may include an end effector including a staple holder, an anvil movable relative to the staple holder, and staples held within the staple holder; a shaft extending from the end effector; a handle attached to the shaft, the handle including a single trigger; wherein actuation of the single trigger in a clamping mode clamps the end effector; and wherein actuation of the single trigger in a stapling mode deploys the staples.

Abstract: A surgical cutting and fastening instrument is disclosed. The surgical cutting and fastening instrument comprises a pair of jaws comprising a distal end, a motor-powered firing member configured to move longitudinally along the pair of jaws toward the distal end, and a sensor configured to sense a fully-closed state of the pair of jaws. The surgical cutting and fastening instrument further comprises, one, a control circuit electrically coupled to the sensor, wherein the control circuit is configured to prevent a longitudinal movement of the firing member toward the distal end if the pair of jaws is not in the fully-closed state and, two, a remote user-controlled console.

Abstract: A surgical instrument is disclosed. The instrument comprises a rotary motion generator, a trigger configured to actuate the rotary motion generator, and a shifting assembly. The shifting assembly comprises a first gear selectively drivable by the rotary motion generator, a second gear selectively drivable by the rotary motion generator, and a toggle configured to switch between the selective drivability of the first gear and the selective drivability of the second gear. The shifting assembly further comprises a biasing mechanism engaged with the toggle, wherein the biasing mechanism is configured to motivate and maintain an operative meshment between the rotary motion generator and one of the first gear and the second gear. The surgical instrument further comprises a rotatable shaft, an end effector comprising a first iaw and a second iaw, and a firing member moveable relative to the end effector during a firing motion.

Abstract: A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines may include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another such that they overlap in the planar configuration.

Abstract: In various embodiments, a compensator can be attachable to an anvil of a fastening instrument. The compensator can comprise a support layer configured to be attached to the anvil and a scaffold attached to the support layer. In at least one embodiment, the scaffold can comprise a plurality of scaffold layers comprised of a biocompatible material and a plurality of cavities, wherein the layers and the cavities can define a matrix favorable to tissue and cellular ingrowth.

Abstract: A method and devices that endoscopically create an anastomosis between two sections of the digestive tract, thereby allowing at least some chyme to bypass a section of the digestive tract while, optionally, the remaining chyme passes through the entire tract.