Patents Issued in May 10, 2016
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Patent number: 9333305Abstract: The autoinjector systems disclosed herein provide in part devices for allowing patients with reduced joint strength to more easily administer medicine. Certain exemplary syringe embodiments include a housing, a syringe assembly slidably mounted on the housing, and a needle cap releasably engaged to the housing, where the cap includes a protruding pocket for receiving a needle cap remover.Type: GrantFiled: December 22, 2014Date of Patent: May 10, 2016Assignee: UCB BIOPHARMA SPRLInventors: Martin John McLoughlin, Alex Lee, Daniel Formosa, Steven Vordenberg, Joern Vicari, Eric Freitag, Boris Kontorvich
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Patent number: 9333306Abstract: Disclosed is a safety needle assembly has a needle guard that prevents accidental needle sticks before and after an injection. A locking collar rotates during use as an inner protrusion follows three paths of a track located on the outer surface of a body housing. When the inner facing protrusion is in the third path, it encounters a hard stop and a rotational bias that locks the guard from further retraction and, thus, covers the sharp distal end of the needle.Type: GrantFiled: March 23, 2011Date of Patent: May 10, 2016Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: David John Cross, Malcolm Stanley Boyd, Alasdair George Young, Naceur Rekaya
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Patent number: 9333307Abstract: An injection device (100), provided for injection with an injection syringe (50) into an organism (1), comprises a guide device (10) designed to receive the injection syringe (50), wherein an injection needle (51) and a syringe body (52) of the injection syringe (50) can be moved relative to the guide device (10), in an advance movement towards or in a withdrawal movement away from the organism (1), and an actuating device (20) to which the injection syringe (50) can be coupled and which is used to actuate the injection syringe (50) for injection of an injectable substance into the organism (1), wherein the actuating device (20) has an actuating element (21) which forms an abutment for a piston device (53) of the injection syringe (50) on the guide device (10), in such a way that, during the withdrawal movement, the piston device (53) executes a relative movement counter to the injection needle (51) and the syringe body (52).Type: GrantFiled: July 25, 2008Date of Patent: May 10, 2016Assignee: INNOVACELL BIOTECHNOLOGIE AGInventors: Wolfgang Schwaiger, Rainer Marksteiner
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Patent number: 9333308Abstract: A fluid transfer device such as a syringe may include a fluid chamber in communication with a male connector tip. The male connector tip is tapered to form a friction fit when inserted in a corresponding female hub. A disconnecting member, e.g., in the form of a lever member has a front surface moveable along the male connector tip between a first position proximal to the fluid chamber and a second position spaced from the first position towards a distal end of the male connector tip so as to release the friction fit. A catch is arranged to catch the female hub after it has been released from the friction fit by the lever member moving towards the second position. The catch may be released when the lever member pivots back towards the first position under the resilient bias of a spring tongue.Type: GrantFiled: April 30, 2013Date of Patent: May 10, 2016Assignee: CONCEPTOMED ASInventors: Christian Mide, Marius Andresen, Rolf BlomvÄgnes, Kevin Geers
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Patent number: 9333309Abstract: An injection device that comprises a chamber configured for containing a substance to be injected and a needle operatively associated with the chamber and having a length sufficient to deliver the substance to an intradermal injection site. A collar surrounds the needle, defining a collar cavity. The collar also has a peripheral forward skin-contacting surface that surrounds and is radially spaced from the needle and injection site by an area that is sufficiently large to allow a patient's skin to move into the collar cavity to properly position the needle for intradermal delivery of the substance to the injection site to allow spread of the injected substance under the skin while inhibiting or preventing backpressure within the skin from forcing the substance out through the injection site.Type: GrantFiled: June 22, 2014Date of Patent: May 10, 2016Assignee: Antares Pharma, Inc.Inventors: Peter L. Sadowski, Paul R. Lesch, Jr., David L. Bremseth
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Patent number: 9333310Abstract: A sheet driver for use in a medicament dispenser with blister pockets includes: (a) a base, extending from the base, (b) a shaft defining a rotational axis; at the base, (c) a drive surface for receipt of drive to rotate the base about the rotational axis; about the shaft, (d) a torsion spring defining first and second spring legs; mounting about the shaft and the torsion spring for rotation about the rotational axis, and (e) a hub defining a hub surface for receipt of a sheet of the medicament carrier, the hub surface being adapted to provide an initial effective winding surface which provides uniform indexing of the medicament carrier.Type: GrantFiled: May 30, 2012Date of Patent: May 10, 2016Assignee: Glaxo Group LimitedInventors: Christopher John Jones, James John May, Daniel Thomas De Sausmarez Lintell, Mark Gregory Palmer, Robert William Tansley
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Patent number: 9333311Abstract: This invention discloses an electronic cigarette and an electronic cigarette device, the electronic cigarette includes a cartridge and a power unit, the cartridge defines atomizing chambers therein, the power unit includes a power supply therein, the atomizing chambers are mutually parallel to each other, the electronic cigarette further comprises a controller connecting the power supply and the atomizing chambers to control the atomizing chambers to work. The electronic cigarette and the electronic cigarette device of the invention have multiple atomizing chambers parallel to each other, and the controller which connects the power supply and the atomizing chambers to control the atomizing chambers to work, thereby achieving big and thick smoke for good flavor. On the other hand, the atomizing chambers accommodate different types of smoke oils, this makes the electronic cigarette to generate smoke with multiple mixed flavors, thus, the users can change the flavors of smoke as they like.Type: GrantFiled: August 31, 2012Date of Patent: May 10, 2016Assignee: HUIZHOU KIMREE TECHNOLOGY CO., LTD., SHENZHEN BRANCHInventor: Qiuming Liu
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Patent number: 9333312Abstract: A breathing apparatus has an expiratory flow sensor unit, an expiratory pressure sensor unit, an expiratory pressure regulator, and an expiratory control unit operatively connected to the expiratory pressure sensor unit for a feedback control of an expiratory pressure during an expiratory phase of a breathing cycle. The expiratory control unit is adapted to provide a real time target pressure value during the expiratory phase to the expiratory pressure regulator for adjusting a desired positive end expiratory pressure (PEEP) level (PEEPset) based on an inspiratory tidal volume of an inspiratory phase of the same breathing cycle and a currently accumulated expiratory tidal volume measured by the expiratory flow sensor unit. In this manner advantageous regulation of PEEP with minimized work of breathing is obtained.Type: GrantFiled: March 27, 2009Date of Patent: May 10, 2016Assignee: Maquet Critical Care ABInventors: Erik Cardelius, Mathias Eklund
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Patent number: 9333313Abstract: A patient interface device (10, 10?, 62, 62?, 102, 152, 162, 172) is provided that includes a patient sealing assembly (12, 64, 104), such as a mask having a rigid shell and a cushion coupled to the rigid shell, a forehead support (26, 72, 118) coupled to the patient sealing assembly, and a hinge assembly (40, 40?, 84, 84?, 124, 154, 164, 174) provided between a top portion of the patient sealing assembly and the forehead support.Type: GrantFiled: February 24, 2011Date of Patent: May 10, 2016Assignee: KONINKLIJKE PHILIPS N.V.Inventor: Richard Thomas Haibach
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Patent number: 9333314Abstract: An patient interface that reliably maintains a seal between it and the patient. The patient interface advantageously includes a deformation portion at its point of connection with an air supply, with the deformation portion being relatively more deformable than the other portions of the patient interface in order to resist torque applied by the air supply from disturbing the seal between the patient interface and the patient. While the air supply is pivotably connected with the patient interface and is pivotable about a pivot axis, a torque applied about an axis other than the pivot axis results in deformation of the deformation portion and thus advantageously avoids breaking the seal between the patient interface and the patient.Type: GrantFiled: September 17, 2012Date of Patent: May 10, 2016Assignee: KONINKLIJKE PHILIPS N.V.Inventor: Gregory John Jablonski
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Patent number: 9333315Abstract: A nasal cannula can be shaped to fit within a user's nares, where the nasal cannula includes at least one prong allowing high flow delivery of humidified gases and creates positive airway pressure in the patient's airway. The prongs can have angled ends such that, in use, gases flowing through the prongs are directed to the user's nasal passages. The nasal cannula body can be partially swiveling and preferably has a ball joint connector. The nasal cannula can have at least one flared end prong that preferably seals within a patient's nare.Type: GrantFiled: September 4, 2015Date of Patent: May 10, 2016Assignee: Fisher & Paykel Healthcare LimitedInventors: Alastair Edwin McAuley, Craig Robert Prentice, Oliver Gleeson
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Patent number: 9333316Abstract: A drug administration controller has a sensor that generates a sensor signal to a physiological measurement device, which measures a physiological parameter in response. A control output responsive to the physiological parameter or a metric derived from the physiological parameter causes a drug administration device to affect the treatment of a person, such as by initiating, pausing, halting or adjusting the dosage of drugs administered to the person.Type: GrantFiled: May 18, 2012Date of Patent: May 10, 2016Assignee: MASIMO CORPORATIONInventor: Massi E. Kiani
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Patent number: 9333317Abstract: A system for respiratory therapy that includes a nebulizer, an adaptor, and a nasal cannula. The nebulizer is operable to generate an aerosolized medicament and pass the aerosolized medicament through a nebulizer outlet port. The adaptor has a nebulizer coupling port configured to be coupled to the nebulizer outlet port. The nasal cannula is configured to provide a flow of breathing gas from a breathing gas source to the patient. The nasal cannula includes at least one nasal prong and an attachment device positioned adjacent the at least one nasal prong. The attachment device is configured to secure the adaptor outlet port adjacent an outlet of the nasal prong. A method for respiratory therapy includes securing a nasal cannula to the patient, attaching an adaptor to the nasal cannula, generating an aerosolized medicament, transferring the aerosolized medicament into the adaptor, and providing a flow of breathing gas to the patient.Type: GrantFiled: January 24, 2013Date of Patent: May 10, 2016Assignee: Vapotherm, Inc.Inventors: Felino V. Cortez, Jr., William F. Niland, George McGarrity
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Patent number: 9333318Abstract: A system for treating a patient suffering from obstructive sleep apnea may include a mask, a portable air flow generator configured to generate air flow at a relatively low flow rate, and a tube connecting the air flow generator and the mask such that air flow from the generator passes through an air flow generator valve on the mask. The mask may include a contact surface for forming a seal between the mask and the patient's face such that the mask surrounds the patient's nostrils, an expiration valve that opens during expiration, and an air flow generator valve that opens during inspiration. In some embodiments, the mask may further include an inspiration valve that opens during inspiration to allow air from outside the system to enter the mask.Type: GrantFiled: April 11, 2013Date of Patent: May 10, 2016Assignee: FRESCA Medical, Inc.Inventors: Andrew H. Cragg, John Logan, John Trusheim, John Nolting, Eugene Chen, Mark Adler
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Patent number: 9333319Abstract: The invention relates to a method and an illumination device arranged for reducing sleep inertia and/or for controlling alertness of a human being. The illumination device is arranged for reducing sleep inertia and/or controlling alertness by light radiation. The illumination device comprises one or more light sources for generating a first illumination output and a second illumination output. The first illumination output comprises light with a dominant wavelength in the range of 590-770 nm. The second illumination output comprises light with a dominant wavelength in the range of 400-560 nm. Thus, colored light is used. Alternatively, the first illumination output comprises white light with a color temperature below 4100 K, i.e. warm white light. The second color temperature then comprises white light with a color temperature above 4900 K.Type: GrantFiled: April 13, 2010Date of Patent: May 10, 2016Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Lucas Josef Maria Schlangen, Vanja Hommes
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Patent number: 9333320Abstract: The present invention relates to an open type car treatment module which, when worn, allows simultaneous laser therapy and music therapy for brain-nervous system tissue by arranging the light source for low level laser therapy (LLLT) and sound source for music therapy (MT) properly, and can release the heat generated by the light source to outside by allowing ventilation with outside through open type configuration of module itself.Type: GrantFiled: November 22, 2011Date of Patent: May 10, 2016Assignee: Industry-Academic Cooperation Foundation, Dankook UniversityInventors: Jin Chul Ahn, Chung Ku Rhee, Pill Sang Chung, Myung Whan Suh
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Patent number: 9333321Abstract: The invention provides a catheter for placement within a vessel of a patient. The catheter comprises an elongated catheter body, a septum extending longitudinally through the interior of the catheter body from the dividing the interior of the catheter body into a first lumen and a second lumen. Each lumen has curved or angled internal walls at the distal end of the catheter that terminate at ports located on opposing sides of the catheter body. The invention also provides a method for exchanging fluids in a patient comprising the step of positioning the catheter of the present invention in communication with a fluid-containing vessel of a patient. The method is particularly well-suited for hemodialysis, plasmapheresis, and other therapies which require removal and return of blood from a patient.Type: GrantFiled: April 23, 2012Date of Patent: May 10, 2016Assignee: AEGIS MEDICAL TECHNOLOGIES, LLCInventor: Timothy W. I. Clark
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Patent number: 9333322Abstract: A transluminal device may include an elongate section extending between a proximal end and a distal end of the device. The elongate section may be configured to be inserted into a body cavity. The device may include a balloon within the elongate section between the proximal end and the distal end.Type: GrantFiled: September 26, 2014Date of Patent: May 10, 2016Assignee: Boston Scientific Scimed, Inc.Inventors: Gary S. Kappel, Jessica Schenck
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Patent number: 9333323Abstract: Stylet assemblies include one or more securing members extending from a base portion of the stylet assembly and configured to removably attach to a portion of an associated structure. Catheter kits and catheter assemblies may include such stylet assemblies. Methods of using a catheter assembly may include inserting at least a portion of a stylet coupled to a stylet cap in a catheter associated with a catheter connection and securing a portion of the stylet cap to only a portion of the catheter connection hub.Type: GrantFiled: October 28, 2011Date of Patent: May 10, 2016Assignee: Custom Medical Applications, Inc.Inventors: Sandor N. Racz, Gabor J. Racz
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Patent number: 9333324Abstract: Embodiment methods of treating a human or animal patient using a remotely controlled catheter insertion system include inserting a catheter handle of a catheter into a handle controller of the remotely controlled catheter insertion system, operating the catheter remotely with the remotely controlled catheter insertion system to introduce the catheter into a body of the patient, and performing a diagnostic or therapeutic procedure on the patient using the catheter. Diagnostic or therapeutic procedures may include a mapping procedure, an ablation procedure, an angioplasty procedure, a drug delivery procedure; an electrophysiology procedure, a radiological procedure, and a medical device implantation or positioning procedure.Type: GrantFiled: November 22, 2013Date of Patent: May 10, 2016Assignee: CATHETER ROBOTICS INC.Inventors: Todd J. Cohen, Michael Eilenberg
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Patent number: 9333325Abstract: A catheter tunneling adapter including a longitudinal body having a distal end and a proximal end and a passageway extending from an entrance at the proximal end to an exit at the distal end. The passageway has a first hemisphere and a second hemisphere with the first hemisphere defining a generally unobstructed first passageway portion from the entrance to the exit. A guide ramp is positioned within the second passageway and tapers towards the first hemisphere moving from the proximal end to the distal end. The ramp defines a longitudinal notch therethrough such that a second passageway portion extends from the entrance to the exit.Type: GrantFiled: March 13, 2013Date of Patent: May 10, 2016Assignee: Medical Components, Inc.Inventors: Charles Scandone, Jr., Mark S. Fisher
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Patent number: 9333326Abstract: A guide wire has a coil body covered with a hydrophilic coating film that exhibits sufficient lubricity even when there is little moisture in its surroundings. In the coil-type guide wire, a coating portion is formed by a plurality of layers where the innermost layer includes a hydrophobic film and an outer layer includes a hydrophilic film. Portions of the innermost layer extend between adjacent coils of the coil body and spaces are formed between the outer layer thereof and the portions of the innermost layer between the coils. The spaces allow moisture to pool so that when moisture in the guide wire's surroundings decreases, it is possible to supply the moisture pooled in the spaces to the hydrophilic film. Thus, even when there is little moisture in the guide wire's surroundings, it is possible to have a sufficient amount of lubricity.Type: GrantFiled: June 25, 2014Date of Patent: May 10, 2016Assignee: ASAHI INTECC CO., LTD.Inventor: Keigo Takada
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Patent number: 9333327Abstract: Described herein are methods and devices for delivering a drug to the frontal sinus system. An inflatable implant is positioned within the frontal sinus system using an anchoring means secured within the frontal sinus cavity. A drug-containing fluid is released directly into the frontal sinus drainage system.Type: GrantFiled: April 23, 2010Date of Patent: May 10, 2016Assignee: ENTELLUS MEDICAL, INC.Inventors: Reuben C. Setliff, III, Peter T. Keith
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Patent number: 9333328Abstract: A device for reducing pressure within a lumen includes a reservoir structured for holding a fluid therein, an injection port in fluid communication with the reservoir, a compliant body structured to expand and contract upon changes in pressure, and a conduit extending between and fluidly coupling the reservoir and the compliant body. The fluid may be a compressible or a noncompressible fluid.Type: GrantFiled: April 15, 2014Date of Patent: May 10, 2016Assignee: Aria CV, Inc.Inventors: John Scandurra, Karl Vollmers
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Patent number: 9333329Abstract: A device that delivers one or more substances into a vaginal lumen according to one of a plurality of release patterns. The device comprises a supporting structure, substance dispensers, and/or coupling elements which are configured to release one or more substances, for example, drugs, in manner designed to optimize treatment of one or more medical conditions.Type: GrantFiled: March 2, 2009Date of Patent: May 10, 2016Inventor: Elan Ziv
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Patent number: 9333330Abstract: A micro-needle (4) comprising a sharp tip (31), an elongated body (32) and a head (36) containing at least two parallel independent lumens (5, 6), each of said lumens (5, 6) communicating with a distal side opening (7, 8) of the head (36); said openings (7, 8) being essentially oriented in a direction which is perpendicular with respect to its lumen (5, 6) main direction and wherein the distal top end (33, 34) of said lumen (5, 6) is in the head (36) of the micro-needle (4).Type: GrantFiled: May 19, 2010Date of Patent: May 10, 2016Assignee: DEBIOTECH S.A.Inventors: Francois Cannehan, Astrid Cachemaille
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Patent number: 9333331Abstract: A transcutaneous access port to a user has a coupling member destined to be anchored in a bone of the user. A first valve system is removably connectable to the coupling member and a second valve system is removably connected to the first valve system. An internal conduit is connected at its proximal end to the access port and at its distal end to a vascular structure of the user. An external conduit is connected to the access port and to an extracorporeal device. A traversing cavity is formed in the bone at an implantation site of the user, passing the internal conduit. The internal conduit is routed through the traversing cavity to connect its distal end to the vascular structure of the user. The coupling member is anchored to the bone at the implantation site. The proximal end of the internal conduit is connected to the access port.Type: GrantFiled: November 8, 2011Date of Patent: May 10, 2016Assignee: Cendres+Metaux SAInventors: Daniel Schutz, Jean-Marc Guenat, Adrian Auderset, Rudolf Hausler, Felix Frey, Anja Kruse, Andreas Arnold, Christof Stieger, Marco Domenico Caversaccio
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Patent number: 9333332Abstract: A valve for medical instruments having a canal configured in a medical instrument and serving as input for at least one additional medical instrument is insulated from a distal-end fluid, whereby the valve housing wherein at least one fluid opening is configured, and positioned in the housing at least one insulating body can be inserted at least partly into the canal. The invention has at least one fluid opening configured in the valve housing by which the fluid can be conducted to the outside of the insulating body such that the fluid opening is so configured that the distal-side fluid can be guided out of the canal to the outside of the insulating body in such a way that the distal-side fluid reshapes the insulating body inward, insulating it, to be essentially perpendicular to the longitudinal direction of the insulating body.Type: GrantFiled: September 19, 2005Date of Patent: May 10, 2016Assignee: Karl Storz GmbH & Co. KGInventors: Peter Eisenkolb, Andreas Efinger
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Patent number: 9333333Abstract: An electrode including a non-conductive substrate having a top surface and at least one channel extending therethrough, an electrically conductive trace material positioned adjacent a portion of the top surface of the non-conductive substrate and extending through the channel, and adapted for electrically coupling to a power source, and a second electrically conductive material that is inert or more corrosion resistant than the trace material. The second material is positioned adjacent to and entirely covering a top surface of the trace material. The electrode further includes a conductive hydrogel laterally offset from the trace material, the hydrogel may be positioned adjacent to a portion of a top surface of the second electrically conductive material.Type: GrantFiled: February 22, 2012Date of Patent: May 10, 2016Assignee: ETHICON, INC.Inventors: Rex O. Bare, Bradley Sargent
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Patent number: 9333334Abstract: Methods for attaching a wearable neurostimulator to a user's head (or head and neck) using a cantilever electrode apparatuses for neuromodulation. In practice an electrode assembly may mate with the wearable neuromodulation devices so that the device is worn over one portion of the electrode assembly while the rest of the electrode assembly attaches to another portion of the body. The neuromodulator may be worn on a portion of the electrode assembly in a cantilevered manner (e.g., held at one end while the opposite end is free-floating), which allows the rigid neuromodulation device to conform to a variety of user head sizes and shapes.Type: GrantFiled: February 27, 2015Date of Patent: May 10, 2016Assignee: thync, inc.Inventors: Douglas Jeffery, Isy Goldwasser, Wing Law, Remi Demers, Jay Frederick Hamlin, Daniel Z. Wetmore, Sumon K. Pal, Jonathan Charlesworth, William J. Tyler
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Patent number: 9333335Abstract: This implantable microcatheter includes a hollow tube with a central lumen extending throughout the length of the tube from a proximal region to a distal region. The bending stiffness of the proximal region is greater than the bending stiffness of the distal region, and the tube has a transition region having a decreasing stiffness gradient from the proximal region to the distal region. The tube wall is free of shielding or armor at least in the distal region, and the catheter is made of biocompatible material(s) suitable for a permanent implantation in venous, arterial or lymphatic networks.Type: GrantFiled: July 5, 2013Date of Patent: May 10, 2016Assignee: SORIN CRM S.A.S.Inventors: Jean-François Ollivier, Nicolas Shan, Willy Régnier
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Patent number: 9333336Abstract: A method of manufacturing an implantable medical lead is disclosed herein. The method may include: providing a lead body including a proximal end, a distal end, and an electrode near the distal end; provide a conductor extending between the proximal and distal ends; providing a crimp including a ribbon-like member and extending the ribbon-like member around the conductor; and mechanically and electrically connecting the ribbon-like member to the electrode.Type: GrantFiled: October 11, 2013Date of Patent: May 10, 2016Assignee: PACESETTER, INC.Inventors: Keith Victorine, Steven R. Conger, Greg Kampa, Dorab N. Sethna, Daniel Ephraim, Sean Matthew Desmond
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Patent number: 9333337Abstract: A method of fabricating electrical feedthroughs coats of a plurality of electrically conductive wires with an electrically insulating material and bundles the coated wires together in a substantially parallel arrangement. The bundled coated wires are secured to each other by joining the electrically insulating material of adjacent wires together to form a monolithic block which is then cut transverse to the wires to produce a block section having opposing first and second sides with a plurality of electrically conductive feedthroughs extending between them.Type: GrantFiled: May 16, 2012Date of Patent: May 10, 2016Assignee: Lawrence Livermore National Security, LLCInventors: Kedar G. Shah, William J. Benett, Satinderpall S. Pannu
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Patent number: 9333338Abstract: A method is described to implant a cochlear implant electrode into a cochlea having a single internal cavity defined by an outer cavity wall. An implantable electrode array is made of a resilient electrode carrier material and has an outer surface with one or more stimulation contacts for delivering the electrical stimulation signals to adjacent neural tissue. A distal end of the electrode array is attached to an insertion line made of a line material different from the electrode carrier material. The distal end of the electrode array is inserted through a single cochleostomy opening into the cochlea while an extra-cochlear end of the insertion line is held outside the cochleostomy opening. The remainder of the electrode array is inserted through the cochleostomy opening into the cochlea while continuing to hold the extra-cochlear end outside the cochlea to maneuver all of the stimulation contacts against the outer cavity wall.Type: GrantFiled: October 10, 2014Date of Patent: May 10, 2016Assignee: MED-EL Elektromedizinische Geraete GmbHInventors: Anandhan Dhanasingh, Claude Jolly, Rocco Calabrese Gac
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Patent number: 9333339Abstract: An apparatus for treating pain by electrical stimulation is disclosed. A lead is placed subcutaneously in the region of pain. The subcutaneous tissue is electrically stimulated to cause paresthesia. The method encompasses subcutaneous placement of an electrical lead near the region of pain and subsequent electrical stimulation of the tissue to cause paresthesia. In particular, an apparatus for treating intractable lower back pain using percutaneous electrostimulation techniques is disclosed.Type: GrantFiled: October 13, 2011Date of Patent: May 10, 2016Inventor: Richard L. Weiner
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Patent number: 9333340Abstract: Various methods and apparatus for treating a condition associated with impaired glucose regulation in a subject comprising in one embodiment, applying a neural conduction block to a target nerve at a blocking site with the neural conduction block selected to at least partially block nerve pulses. In another embodiment, combinations of down-regulating and or up-regulating with or without pharmaceutical agents are used to treat impaired glucose regulation. In other embodiments, up-regulation or down-regulation of various nerves, such as the vagus and its branches, and the splanchnic is used to modify the production of GLP-1 and GIP, thereby controlling glucose levels. In yet further embodiments, combinations of down-regulating and or up-regulating with or without pharmaceutical agents are used to modify the production of GLP-1 and GIP, to treat impaired glucose regulation.Type: GrantFiled: November 20, 2012Date of Patent: May 10, 2016Assignee: EnteroMedics Inc.Inventors: Arnold W. Thornton, Dennis Dong-won Kim, Mark B. Knudson, Katherine S. Tweden, Richard R. Wilson
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Patent number: 9333341Abstract: An implantable lead for placement by means of a guide wire passing therethrough. The lead has an elongated insulative lead body with an axially extending lumen through at least a distal portion of the lead body. A conductor is mounted within and extends to an electrode assembly mounted to a distal portion of the lead body. A seal housing with a seal located therein located at a distal end of the lead body. The seal is located generally perpendicular to the axis of the lead body and is concave on both its proximal and distal sides. The housing is provided with a cavity adjacent each of the seal's proximal and distal sides, into which the seal may be deflected. The electrode assembly may be mounted to the seal housing.Type: GrantFiled: September 30, 2009Date of Patent: May 10, 2016Assignee: Medtronic, Inc.Inventors: John Louis Sommer, Jon D. Schell
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Patent number: 9333342Abstract: Devices or methods such as for stimulating excitable tissue or sensing physiologic response or other signals that can use chronic fixation mechanism are described. An implantable apparatus can comprise an electrostimulation electrode assembly that can include a primary fixation member and a secondary fixation member. The primary fixation member can be actively engaged or affixed to a target tissue of a patient, and the second fixation member can be biased against the target tissue, collapsed or compressed against the target tissue when the primary fixation member is affixed to the target tissue. The electrostimulation electrode assembly can also include at least one electrode such as to contact heart or other excitable tissue such as to deliver chronic electrostimulation or sensing physiologic responses.Type: GrantFiled: July 21, 2014Date of Patent: May 10, 2016Assignee: CARDIAC PACEMAKERS, INC.Inventors: Benjamin J. Haasl, Brian L. Schmidt, Arthur J. Foster
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Patent number: 9333343Abstract: Embodiments disclosed herein are directed to systems configured to power at least one device disposed in a living subject, apparatuses configured to be disposed in a living subject and export power stored in an energy-storage device, and related methods of powering at least one device disposed in the living subject.Type: GrantFiled: September 25, 2012Date of Patent: May 10, 2016Assignee: GEARBOX, LLCInventors: Roderick A. Hyde, Muriel Y. Ishikawa, Dennis J. Rivet, Lowell L. Wood, Jr., Victoria Y. H. Wood
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Patent number: 9333344Abstract: A medical device lead includes an insulative body having a proximal region with a proximal end, and a distal region with a distal end. The medical device lead also includes a connector coupled to the proximal end of the insulative body of the lead to electrically and mechanically connect the lead to an implantable pulse generator. The medical device lead further includes a conductor extending through the insulative body with a proximal end electrically connected to the connector. A distal electrode assembly at a distal end of the insulative body includes a proximal portion electrically coupled to a distal end of the conductor, a distal portion, and an intermediate portion. The intermediate portion comprises a coiled element electrically connecting the proximal portion and distal portion.Type: GrantFiled: December 22, 2014Date of Patent: May 10, 2016Assignee: Cardiac Pacemakers, Inc.Inventor: Arthur J. Foster
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Patent number: 9333345Abstract: An electrical stimulation system and method for generating a stimulation signal for at least two electrodes coupled to a body part in a functional electrical stimulation system. One example embodiment includes a controller unit operable for receiving stimulation parameters and a trigger signal, and in response to receiving the trigger signal, outputting control signals based on the stimulation parameters. A voltage conversion module coupled to the unit receives the control signals and converts a supply voltage based on the received control signals. A switch receives the converted supply voltage at a first terminal and outputs a simulation signal at a second terminal. Outputting of the converted supply voltage at the second terminal by the switch is controlled by a driver module based on the received control signals.Type: GrantFiled: October 3, 2014Date of Patent: May 10, 2016Assignee: Ensilver CanadaInventors: Farsad Kiani, Elias Koikas, Qiang Song, Jinbiao Zheng, Edgardo Zaragoza, Arthur Kwok
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Patent number: 9333346Abstract: A microcurrent stimulation device with a power supply, two or more electrodes electronically coupled to the power supply, a microcontroller configured to generate an electromagnetic waveform, an impedance measurement module configured to measure electrical impedance of one or more biological tissues between the two or more electrodes. A first safety circuit monitors electric current flow through one or more components of the microcurrent stimulation device and interrupts electric current flow if the electric current flow through the one or more components is above a predetermined level. A second safety circuit interrupts electric current flow through the one or more components if a firmware failure occurs.Type: GrantFiled: May 20, 2014Date of Patent: May 10, 2016Assignee: TAMA Research Corp.Inventor: Ali Shambayati
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Patent number: 9333347Abstract: A non-invasive electrical stimulation device shapes an elongated electric field of effect that can be oriented parallel to a long nerve, such as a vagus nerve in a patient's neck, producing a desired physiological response in the patient. The stimulator comprises a source of electrical power, at least one electrode and a continuous electrically conducting medium in which the electrode(s) are in contact. The stimulation device is configured to produce a peak pulse voltage that is sufficient to produce a physiologically effective electric field in the vicinity of a target nerve, but not to substantially stimulate other nerves and muscles that lie between the vicinity of the target nerve and patient's skin. Current is passed through the electrodes in bursts of preferably five sinusoidal pulses, wherein each pulse within a burst has a duration of preferably 200 microseconds, and bursts repeat at preferably at 15-50 bursts per second.Type: GrantFiled: July 22, 2014Date of Patent: May 10, 2016Assignee: Electrocore, LLCInventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
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Patent number: 9333348Abstract: A diagnostic device in an electrical interferential treatment regime applies different pulse frequencies in one selection of electrode placement and determines the change of blood flow in response to the change in pulse frequency in an attempt to determine an optimum or workable set of parameters. The device includes electronic storage to record a series of tests and their results and a communication link. The communication link enables a professional caregiver to determine whether the parameter determinations, made at a location remote from the professional's office, such as at the residence of the patient, were conducted and were conducted correctly. The communication link also enables the professional to determine whether the treatments were conducted and conducted correctly.Type: GrantFiled: June 22, 2015Date of Patent: May 10, 2016Inventor: Donald Alan Rhodes
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Patent number: 9333349Abstract: Disclosed is a bio-feedback type device for physical pain relief at childbirth, comprising a maternal-fetal monitoring module, a hand-grip pressure transducer, an electrical-stimulation wave group generator, an electrical-stimulation wave group output module and a childbirth pain-relief workstation.Type: GrantFiled: November 13, 2013Date of Patent: May 10, 2016Assignee: Guangzhou Sunray Medical Apparatus Co., Ltd.Inventors: Yaosheng Lu, Jianguo Qi, Kun Fang, Ruyi Qin, Zhan Lin, Jingbo Rong, Haifeng Chen
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Patent number: 9333350Abstract: A therapy system for managing a psychiatric disorder of the patient may be controlled based on a patient mood state. Therapy may be delivered to a patient according to a therapy program, and a physiological parameter of the patient may be monitored during or after therapy delivery. The patient mood state may be determined based on the monitored physiological parameter, and the therapy delivery may be controlled based on the determined mood state. In some embodiments, the therapy delivery is stopped prior to determining the patient mood state and the therapy delivery is restarted upon detecting a negative mood state. In other embodiments, therapy delivery is delivered until a positive mood state is detected, at which point the therapy delivery may be stopped.Type: GrantFiled: April 17, 2009Date of Patent: May 10, 2016Assignee: Medtronic, Inc.Inventors: Mark T. Rise, Jonathon E. Giftakis, Paul H. Stypulkowski, Timothy J. Denison, Nathan A. Torgerson
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Patent number: 9333351Abstract: Methods and systems are provided to deliver a neural stimulation therapy to treat apnea episodes. The methods and systems detect a respiratory pattern of a patient and identify a type associated with the respiratory pattern. A sleep stage is detected that the patient is experiencing and the method and system identify when the sleep stage warrants therapy. When the respiratory pattern corresponds to an apnea episode (AE) and the sleep stage warrants therapy, the methods and systems deliver an apnea episode terminating neuro-stimulation (AET-NS) therapy configured to terminate the AE. A type of AE therapy that is delivered may be based on the sleep stage that was detected. The methods and systems may determine whether the AET-NS therapy successfully terminated the AE, and, if not, adjust the AET-NS therapy and deliver a new AET-NS therapy.Type: GrantFiled: December 16, 2013Date of Patent: May 10, 2016Assignee: Pacesetter, Inc.Inventors: Edith Arnold, Kritika Gupta, Edward Karst, Allen Keel, Yelena Nabutovsky, Riddhi Shah
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Patent number: 9333352Abstract: Methods and devices for reducing ventricle filling volume are disclosed. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated in a consistent way to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.Type: GrantFiled: March 10, 2015Date of Patent: May 10, 2016Assignee: BackBeat Medical, Inc.Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
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Patent number: 9333353Abstract: The disclosure is directed to a deep brain stimulation (DBS) lead having a distal end for providing therapeutic electrical stimulation to tissue in a stimulation target area of a patient's brain, comprising an array of one or more stimulation elements and sensing elements located at the distal end of the lead. After the first implantation of the lead into the brain along a trajectory that is pre-determined by non-surgical procedures, the array of stimulation and sensing elements is capable of facilitating the location of the target area and the determination for each of the stimulation elements of the required stimulation parameters needed to provide the therapeutic stimulation to the brain tissue in the stimulation target area, without requiring any additional implantations of the lead after the first implantation.Type: GrantFiled: June 9, 2014Date of Patent: May 10, 2016Assignee: Medtronic Bakken Research Center B.V.Inventors: Michel Marcel Jose Decre, Hubert Cecile Francois Martens
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Patent number: 9333355Abstract: A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.Type: GrantFiled: December 4, 2014Date of Patent: May 10, 2016Assignees: MICROTRANSPONDER, INC., THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Michael P. Kilgard, Navzer Engineer, David Michael Pierce, Robert L. Rennaker