Abstract: A dental apparatus includes a light irradiation unit for emitting a light to irradiate an oral cavity, an image capturing unit for image-capturing the oral cavity light irradiated by the light irradiation unit, and an output unit for outputting data for highlighting and displaying at least one of a plaque site and a calculus site on an image of the oral cavity based on an image captured result by the image capturing unit.

Abstract: The present invention provides an image pick-up window defogging function-equipped built-in camera hand piece having a function of treating an affected area and an image observation function of observing the affected area or the like with a camera and capable of defogging the outer surface of an image pick-up window by preventing adhesion of cutting waste and water droplets to the image pick-up window.

Abstract: An optical coupling efficiency detection assembly includes a first housing accommodating a beam splitter and a fiber port, a second housing accommodating a ferrule enclosing a monitoring fiber, and an attachment block attaching the first housing to the second housing to establish a parfocal arrangement among the beam splitter, the fiber port, and the ferrule. Further, an assembly method for the optical coupling efficiency detection assembly is disclosed. The assembly method may include providing a beam splitter and a fiber port in a first housing, providing a ferrule enclosing a monitoring fiber in a second housing, and attaching the second housing to the first housing via an attachment block to establish a parfocal arrangement among the beam splitter, the fiber port, and the ferrule.

Abstract: A device for corneal imaging is disclosed. The device comprises a first camera and processing means. The first camera is configured for imaging a cornea of a user of the device and/or an eyewear worn by the user. The processing means is operative to acquire a first image from the first camera, identify a first reflection by the cornea and/or a second reflection by a reflective surface of the eyewear, and determine a first optical transformation representing the first reflection and/or a second optical transformation representing the second reflection. Embodiments of the invention provide an improved corneal imaging solution for user operated computing devices by taking specular reflections originating from one or more reflective surfaces of an eyewear worn by the user into consideration. Also disclosed are a corresponding method, computer program, and computer program product.

Abstract: A method for quantifying a blood vessel reflection parameter associated with a biological subject, the method including, in at least one electronic processing device determining, from a fundus image of an eye of the subject, edge points of at least one blood vessel in a region near an optic disc, processing the fundus image, at least in part using the edge points, to identify blood vessel edges and central reflex edges, determining blood vessel and central reflex parameter values using the blood vessel edges and determining a blood vessel reflection parameter value at least partially indicative of blood vessel reflection using the blood vessel and central reflex parameter values.

Abstract: An eye fundus image photographing device and method that can acquire images of higher quality. The eye fundus image photographing device photographs a wide-angle eye fundus image on an appropriate exposure condition with respect to a peripheral area different from an optic disk region of an eye fundus area and detects the optic disk region from the wide-angle eye fundus image. Moreover, based on the detection result of the optic disk region, the eye fundus image photographing device photographs a narrow-angle eye fundus image which assumes an area of the optic disk region as an object, on an appropriate exposure condition with respect to the area of the optic disk region. Further, the eye fundus image photographing device generates a synthetic eye fundus image of a high dynamic range by synthesizing the wide-angle eye fundus image and the narrow-angle eye fundus image.

Abstract: An ophthalmologic apparatus includes an error obtaining unit configured to obtain a value corresponding to a difference between a first imaging position which tracks a predetermined position of an eye portion under control of a tracking unit and the predetermined position, a determination unit configured to determine a position which is shifted from the first imaging position which tracks the predetermined position as a second imaging position in accordance with the value corresponding to the difference. The ophthalmologic apparatus averages tomographic images of the first and second imaging positions.

Abstract: Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.

Abstract: Disclosed is a method for determining at least one ocular measurement (pupillary distance, mono pupillary distance and/or heights) of a user, using a consumer-type digital image sensor. The method uses at least one image of the user's head, acquired by the image sensor and containing an object of known size. The calibration parameters of the camera are unknown or known with little precision.

Abstract: A system for tracking eye location is disclosed. Systems in accordance with the present invention include a scanner for sweeping a first optical signal across the surface of an eye, a detector for detecting a second optical signal reflected from the eye, and a detection circuit for determining a maximum intensity in the second optical signal. In operation, the scanner sweeps the first optical signal over the surface of the eye while the detection circuitry determines a plurality of intensity maxima in the second optical signal. The time between the intensity maxima during the sweep is indicative of the location of the cornea within the eye surface.

Abstract: An OCT system comprises an OCT scan module for retinal scanning and an add-on anterior segment scanning module which includes at least one anterior segment scan lens (11) and an add-on fixation target (15) which is used to maintain the viewing direction of the eye (6) under investigation while achieving anterior segment scanning. Because the anterior segment scan module added to the exterior of an existing OCT system for retinal scanning has an add-on fixation target (15), it is possible to maintain the viewing direction of the eye (6) under investigation while carrying out anterior segment scanning without adjusting the internal beam path of the OCT system, and the OCT system of the present invention can be adapted to patients with only one functioning eye.

Abstract: In the present invention, a monitoring device for providing information on data obtained from sensors operably connected to the device includes a central processing unit configured to receive incoming data signals from a sensor concerning a physiological parameter and to compare the incoming data signals to predetermined alarm criteria for the physiological parameter to determine an alarm condition. The device also includes a display operably connected to the central processing unit and having a display screen with a display area configured to visually represent the incoming data signals concerning the physiological parameter relating to a determined alarm condition on a portion of the display area in a visually distinct manner from a remainder of the display area to visually illustrate an escalation effect.

Abstract: A Wireless Monitoring Apparatus is used in conjunction with an automated external defibrillator (AED) system for patient rescue in mass-casualty incidents. The rescuer applies the device on each patient. The wireless monitoring apparatus automatically analyzes the patient's heart rhythm and communicates with the AED system. The AED system is therefore is able to display information with regard to each patient, notifies the rescuer on actions to take and can deliver defibrillation therapy if needed.

Abstract: An image capturing device and a sensing protection device are provided. The image capturing device includes a light source configured to emit lights on a skin, an image sensor configured to obtain an image of the skin from lights reflected from the skin, a sensing protection device, which is an attachable and detachable, configured to surround the light source and the image sensor and includes a connection unit configured to be attached to and detached from the image capturing device, and a controller configured to process characteristics of the skin based on the obtained image.

Abstract: A micro-camera catheter device is disclosed having at least one light source disposed on a distal end of a catheter. The light source is capable of propagating a predetermined wavelength of light with a wavelength greater than approximately 700 nanometers onto a target. The device further includes a lens system disposed on the distal end of the catheter, said lens system configured to receive light reflected from the target. The device further includes a non-linear optical media disposed about the lens system configured to reduce the wavelength of light reflected from the target. The device also includes a silicon-based solid state imaging device disposed behind the non-linear optical media configured to receive light from the non-linear optical media.

Abstract: A method includes obtaining, by an apparatus, heart rate information measured from a user performing a physical activity and user specific information characterizing the user, determining that the heart rate information comprises an interruption period, and generating, based at least on the measured heart rate information and the user parameters, a heart rate change estimation. The heart rate change estimation represents an estimated change in heart rate of the user during the interruption period.

Abstract: A wearable computing device includes an electro-optical sensor to translate received light into an electrical signal. During a first mode of operation of the wearable computing device, a physical parameter of a wearer of the wearable computing device is assessed from the electrical signal. During a second mode of operation of the wearable computing device, encoded communication data is extracted from the electrical signal.

Abstract: An apparatus to measure pulmonary blood flow and cardiac output (Q) comprising: a) a breathing circuit which, at exhalation, keeps exhaled gas separate from inhaled gas and at inhalation, when VE is greater than first gas set (FGS) flow, results in a subject inhaling FGS first and then a second gas set (SGS), for the balance of inhalation; b) a gas sensor for monitoring gas concentrations at the patient-circuit interface; c) a gas flow control means for controlling the rate of FGS flow into the breathing circuit; d) machine intelligence consisting of a computer or logic circuit capable of controlling the gas flow control means which receives the output of the gas sensor means and outputs pulmonary blood flow.

Abstract: The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.

Abstract: According to one embodiment, an apparatus comprising a portable monitoring device to be affixed to a user. The portable monitoring device including: 1) a set of one or more sensors to generate sensor data indicative of physical activity of a user when the portable monitoring device is affixed to the user; and 2) processing circuitry coupled with the set of sensors, to detect that the user has been sedentary for a period of time, and cause the portable monitoring device to alert the user responsive to the detection to encourage the user to move.

Abstract: A method for digital thermal monitoring assessment of vascular function comprising a temporary arterial occlusion using a pneumatic cuff positioned on a subject's upper limb, monitoring skin temperature at the fingertip of the occluded limb for a period of time before, during, and after the occlusion, calculating a Zero Reactivity Curve based on variables including start temperature, room temperature, and the slope of temperature decline during the occlusion, and assessing vascular function based on comparing the Zero Reactivity Curve and the observed temperature rebound after the occlusion is removed.

Abstract: A processing system received data from a Fractional Flow Reserve device and communicates data to a conventional hemodynamic monitoring system having pressure displays. The processing system receives proximal pressure measurement signal from an aortic pressure measurement device and a distal pressure measurement signal from a distal pressure measurement device. A processor computes an FFR ratio from the proximal pressure measurement signal and the distal pressure measurement signal, and converts FFR ratio to a pressure format such that the FFR ratio reads on the conventional hemodynamic monitoring system as a pressure in units of pressure. The processing system transmits the proximal pressure measurement signal, the distal pressure measurement signal, and the FFR ratio in pressure format to the conventional hemodynamic monitoring system.

Abstract: The current invention provides a method of identifying a ischemic lesion. The method includes loading perfusion imaging data into an electronic memory element and deriving perfusion maps from the perfusion imaging data, where the perfusion Performs necessary image pre-processing maps include a cerebral blood volume (CBV) map and an arterial delay time (DT) map, which utilize arterial delay and dispersion effects. Ischemic pixels are determined from the perfusion imaging taking into account arterial delay and dispersion effects data, where the DT is greater than a predetermined first threshold value and the CBV is below a second threshold value and the infarct portion of the ischemic lesion is determined, where DT is greater than a predetermined third threshold value and/or the CBV is below a forth threshold value.

Abstract: An electronic system for estimating a subject's blood pressure, comprising a feature extraction module configured for receiving a subject's photoplethysmogram signal, detecting a plurality of signal characteristic points on the received photoplethysmogram signal, calculating a plurality of distances in both time and amplitude between any two of the detected photoplethysmogram signal characteristic points, and providing a feature information signal comprising information about the calculated distances; and a blood pressure calculation module configured for receiving the photoplethysmogram signal, the feature information signal and anthropometric characteristics of the subject, and calculating systolic, diastolic and continuous mean blood pressure values of the subject.

Abstract: An apparatus for measuring vital signs and various states of health using the underlying concept of Photoplethysmography (PPG). This apparatus comprises one or more light source(s) and one or more detector(s) configured to measure transmitted and/or reflected light within the digits such as a finger or toe, but can also be applied to other soft tissue elements. The apparatus comprises a means to enhance signal quality, control the volume of interrogated tissue and minimize motion artifact. The apparatus comprises a power source. The apparatus may further comprise at least one processor to receive information from the detector and process measured variations in light intensity. This information may be transmitted wirelessly through technology such as Bluetooth. The apparatus may also comprise a system utilizing inductive charging (“wireless charging”).

Abstract: A biological information measurement apparatus capable of improving the SN ratio of a photoplethysmographic signal by reducing stray light in detection light that reaches a light-receiving unit from a light-emitting unit is provided. A biological information measurement apparatus includes a light-emitting unit that irradiates a finger, a light-receiving unit that receives and photoelectrically converts light transmitted through or reflected by the finger and outputs a photoplethysmographic signal, and a processing unit that obtains biological information on the basis of the photoplethysmographic signal. The light-emitting and light-receiving units are disposed, in plan view in a plane perpendicular to the direction of the emitted light or the received light, such that a line passing through the centers of the light-emitting unit and the light-receiving unit is slanted relative to a lengthwise direction of the finger.

Abstract: An atraumatic detection/stimulation lead is disclosed. The lead includes at least one microcable having a core cable comprising a plurality of elementary metal strands. One of the microcables has provided at its distal end an atraumatic protection device. The atraumatic protection device includes a protective coating on the distal ends of the elementary strands of the microcable, and the protective coating is covered by a protective cap of deformable material. The protective cap may be a conical distal end adapted to deform and axially flatten out. The microcable may have an overall diameter less than or equal to 1.5 French (0.50 mm).

Abstract: An implantable device for monitoring for neural injury has a plurality of electrodes including stimulus electrodes and sense electrodes. A stimulus source provides a stimulus to be delivered to a nerve in order to give rise to an evoked action potential. Measurement circuitry records a neural compound action potential signal sensed at the sense electrodes. A stream of control stimuli are applied to the nerve over time and the evoked neural responses are measured. A diagnostic parameter of the measured neural responses is monitored over time, in order to detect a change in the diagnostic parameter. If a change in the diagnostic parameter occurs over time, an indication is output that neural injury has occurred.

Abstract: A method for display, consisting of acquiring an electrical signal from a heart of a subject over multiple heart cycles. The electrical signal is partitioned into a succession of synchronized segments having respective start times at a selected annotation point in the heart cycles. The method includes overlaying respective graphical representations of the synchronized segments in the succession on a display screen, such that each segment is first presented on the display screen with an initial display intensity at a respective display time corresponding to a respective start time of the segment. The method further includes gradually decreasing a display intensity of each segment overlaid on the display screen as a decaying function of a time elapsed since the respective display time.

Abstract: Methods for treating cardiac complex rhythm disorder in a patient can include receiving a plurality of electrical signals from a sensor system, wherein each electrical signal corresponds with a separate location on a cardiac wall of the heart of the patient, and wherein each electrical signal comprises an electrogram waveform; and ranking the electrical signals relative to each other based on at least a uniformity and a frequency of the electrogram waveform of each electrical signal.

Abstract: A system and method to target a biological rhythm disorder, such as a heart rhythm disorder include processing cardiac signals via a computing device to determine a shape in a region of tissue defined by a source associated with the biological rhythm disorder that migrates spatially on or within the shape, and identifying at least one portion of the tissue proximate to the shape to enable selective modification of the at least one portion of tissue in order to terminate or alter the heart rhythm disorder.

Abstract: A medical device may include a sheath, and an elongate member disposed within a distal portion of the sheath, the elongate member configured to reciprocally move between a sheathed configuration and a deployed configuration. The elongate member may be substantially linear and disposed within the sheath while in the sheathed configuration and extend distally from the sheath in a first direction in the deployed configuration. The elongate member may include a first bend disposed distal to the distal portion of the sheath, the first bend directing the elongate sheath in a second direction that is substantially opposite to the first direction, and a second bend distal to the first bend, the second bend directing the elongate sheath in a third direction substantially transverse to the first and second directions.

Abstract: Example methods are disclosed herein that include obtaining electroencephalographic (EEG) data from a subject via a device comprising two or more independently adjustable bands, each of the bands having a plurality of electrodes to detect the electroencephalographic data from a brain of the subject, each band selectively rotatable relative to an adjacent band and each band selectively compressible to increase a force of the electrodes against a head of the subject. The example method also includes converting the EEG data into digital EEG signals and conditioning the digital EEG signals. In addition, the example method includes analyzing the digital EEG signals using one or more analysis protocols to determine a mental characteristic of the subject and transmitting the mental characteristic to an output device.

Abstract: A lightweight, disposable and substantially radiolucent electrode or sensor assembly for that universally connects to separate, non-integrated electrodes or sensors for the monitoring of the physiological parameters of a live subject wherein the electrode assembly is comprised of one or more radiolucent electrical connectors for connecting the electrode assembly to the sensors. The present invention also discloses a method of positioning the electrode assembly on a patient whose physiological signs are being monitored such that access to the patient's chest is substantially unimpeded so as not to obstruct the electromagnetic imaging of the patient's chest, the application of defibrillation paddles or surgical procedures that require access to the chest area.

Abstract: A coordinating interface for electrophysiological signals provides inputs for ECG and intra-cardiac electrodes and provides a computer controllable processing path outputting data using a shareable digital data output. Requests received over a digital control line allow the computer to control a multiway switch and analog filter set to arbitrate among different uses of the electrophysiological signals by different devices. A single coordinating interface helps reduce interference from competing uses. Pre-stored configuration data simplifies the connection of different devices having different uses of the physiological data.

Abstract: In a method and apparatus, magnetic resonance angiography images of an examination volume of a patient are obtained using time-of-flight angiography in a magnetic resonance scanner. By continuous recording, a number of two-dimensional slice images covering the examination volume along an axial direction are acquired in a slice-by-slice layer-wise, such as with overlapping. The slice images are divided into groups of, in each case, a predetermined number of consecutive slice images in the axial direction. A maximum intensity projection image is determined for each group, and the angiography images are determined as the maximum intensity projection images and/or dependent on the maximum intensity projection images.

Abstract: The present invention provides a method of detection of metallic items and/or metallic surgical instruments or articles by a detection device in the event that such articles have been retained in a patient after a surgical procedure. More specifically, the invention relates to a detection system that uses (1) a metal detector or (2) a detector for harmonic-generating amorphous or non-amorphous metallic tags together with three-dimensional spatial position measurement to determine if a foreign metallic article has been retained in the body and if so, to determine the article's location. The invention scans the patient pre- and post-operatively, evaluating three-dimensional differences in electronic response to account for other nearby metallic objects not related to the retained metallic article, thereby determining by inference whether the post-operative electronic response results from presence of a retained article.

Abstract: A surgical site monitoring system and associated method of use employ a single scan-visible passive vectorized fiducial reference attached at a fiducial location near a surgical site. A passive vectorized tracking marker is attached to the fiducial reference. Passive vectorized tracking markers may also be attached to surgical implements used at the surgical site. A scan prior to a surgical procedure with the fiducial reference attached is used to obtain scan data of the surgical site. A tracker obtains image information about the tracking markers and surgical implements. The system and method employ the scan data and image information to track the surgery and the surgical implements relative to the surgical site. The system and method use either markings on or shapes of the tracking markers to determine from the image information the relative 3D locations and orientations of the surgical implements and fiducial reference.

Abstract: The present disclosure provides examples of a method, including: providing a representative inhale-exhale cycle breathing volume over time profile; and when the subject performs at least one inhale-exhale cycle that meets a correspondence criterion related to the representative profile, using data relating to oxygen consumption or carbon dioxide production during the inhale-exhale cycle that met the correspondence criterion to determine a metabolic property in the subject.

Abstract: This document provides systems and techniques that can be used to provide computer-implemented interpretation (e.g., up-to-date, on demand, and real time interpretation) of respiratory profiles of patients using, for example, an application provided by a computer server system, to assess a patient's cardiac and/or pulmonary function.

Abstract: An exhaled breath condensate collection device (10) is described. The device includes a condensation chamber (12) having an inlet and an outlet and arranged such that breath exhaled from the lungs of a user flows through the condensation chamber from the inlet to the outlet; at least one cooling element (16); and a frame (18) supporting the condensation chamber and the at least one cooling element. The frame (18) is movable between a first configuration in which the at least one cooling element is operable to cool the condensation chamber so as to promote the formation of breath condensate in the condensation chamber, and a second configuration in which the cooling element is displaced from the condensation chamber so as to encourage condensate to flow into a collection region in fluid communication with the condensation chamber. To be accompanied by FIG. 5.

Abstract: A sensor grid is provided which is able to provide signals of the magnitude and location on the grid of applied pressure. In the prime application of gait analysis, the sensor in the sole of a shoe provides over time a signal indicative of the magnitude and movement of the centre of pressure. This may be presented as a visual signal showing the location of the centre of pressure on the outline of the sole with pressure values coded in colour. Alternatively the location may be represented as pitch of an audio signal and the magnitude by sound volume. Such a signal can be used to provide feedback to a patient to correct their gait by modifying their gait to produce a desirable signal. The analysis software uses an algorithm to identify the location, speed and distribution of the centre of pressure (COP) and additionally to assess the fractal dimension of the COP. Other attributes such as location of hotspots and pressure impulses can be used to augment the biofeedback signals.

Abstract: This contact-angle measurement method is a contact-angle measurement method for measuring a contact angle (?) between a droplet that is supplied to a sample curved surface and the sample curved surface. This method includes an apparent contact-angle calculation step of calculating an apparent contact-angle (?) of the droplet by using a captured image of the droplet supplied to the sample curved surface and the sample curved surface; an inclination angle calculation step of calculating an inclination angle (?) of the sample curved surface at an outer periphery portion of a contact portion between the droplet and the sample curved surface by using the captured image; and a contact-angle calculation step of calculating the contact angle (?) by correcting the apparent contact angle (?), using the inclination angle (?).

Abstract: Some embodiments of the invention provide methods and apparatus for enhanced real time frailty assessment leveraging a mobile or wearable device. In some embodiments, the mobile or wearable device user's gait characteristics are determined in real time, and said information is integrated with additional information comprising the user's balance evaluation and contextual information obtained making use of the mobile or wearable device sensors, in order to deliver an enhanced frailty assessment.

Abstract: Examples of systems and methods for rapidly grading the hearing of a user in accordance with WHO guidelines are disclosed. One example includes a personal computer and a test device configured to produce calibrated acoustic output at suprathreshold levels presented at an audiometric frequency range from 500 to 4000 Hz. The consumer's minimal response levels are registered, and a hearing ability score is presented to indicate a hearing grade and hearing aid candidacy. The hearing ability score may be representative of a classification of the WHO grading of hearing impairment. Systems and methods disclosed herein, with considerations for room noise present in the consumer's environment, allow for rapid hearing profiling, using a standard personal computer and minimal low-cost hardware, thus particularly suited for self-testing outside clinical environments such as at home, office, or retail store settings.

Abstract: A physiological measurement system has a sensor, a processor, a communications link and information elements. The sensor is configured to transmit light having a plurality of wavelengths into a tissue site and to generate a sensor signal responsive to the transmitted light after tissue attenuation. The attenuated light can be used by the system to determine a plurality of physiological measurements. The processor is configured to operate on the sensor signal so as to derive at least one physiological parameter after which of the plurality of physiological measurements the system is configured to or capable of measuring.

Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Abstract: A microneedle device (200) including at least one microneedle (1) having one or more nanowires (203) on a surface of said at least one microneedle. The microneedle device is typically used in a sensor such as a sensor for monitoring glucose levels in the body and the nanowires may have a membrane (207) covering at least part of the nanowires.

Abstract: Provided is a blood analyte collection device that includes a microneedle array configured to provide fluid communication between a cellular interstitial fluid of a subject and a collection device fluid, a device chamber containing the collection device fluid, and a sequestration material in the device chamber configured to bind to a blood analyte from the cellular interstitial fluid. Also provided are methods and kits that use the subject blood analyte collection device. The subject devices, methods and kits find use in a variety of applications, such as detecting a blood analyte, such as glucose, in a subject.

Abstract: The present disclosure provides devices, methods and systems for analyte detection and/or monitoring, e.g., the continuous and/or semi-continuous monitoring of in-vivo analyte concentrations in real time. Generally, the devices, methods and systems of the present disclosure make use of signaling probes; methods or devices for reducing interferent-based fouling of the signaling probes, non-specific binding to the signaling probes and/or occlusion of a sensor surface; and methods and/or devices for providing an adjusted signal based on a detected signal from the signaling probes. Compositions including conformation switching signaling probes are also provided.