Abstract: Particular embodiments described herein provide for an electronic device, such as a wrist worn electronic device. One particular example implementation of the electronic device may include a main housing, a main display in the main housing, a wrist strap that allows the main housing to be secured to a user such that the main display is located on top of a wrist of the user, and a secondary display located on the wrist strap, where the secondary display communicates information to the user without the user having to turn the wrist.

Abstract: A patient management system of an embodiment includes a server, a plurality of ophthalmic examination apparatuses assigned to a plurality of patients, and a plurality of computers installed in a plurality of medical institutions. The ophthalmic examination apparatuses and computers are communicable with the server via a communication line. The server manages the account of each patient, and the account of each medical institution. Test data obtained by each of the ophthalmic examination apparatuses is stored in the account of a corresponding patient. The server sends information stored in the account of a patient to a computer installed in one of the medical institutions assigned in advance to the patient.

Abstract: The invention regards Multifunction Biotelemetry Support System for Psychophysiology Monitoring measuring physiological values which are further evaluated, characterized by containing at least one translation unit for WiFi access points and one control unit. Each sensory unit includes an EKG sensor, GSR sensor, RR and BPM sensor, body temperature sensor, room temperature sensor, actigraph activity sensor, HRV measurement and evaluation sensor, signal LED and a push button.

Abstract: An eavesdropping arrangement for acquiring a measured physiological variable of an individual includes a receiver and a communication interface in a housing separate from the receiver. The communication interface is positioned along a communication link between a first sensor, which is configured to measure aortic blood pressure and to provide a signal representing measured aortic blood pressure, and a central monitoring device configured to monitor the measured aortic blood pressure. The communication interface includes a connection to the communication link that permits the communication interface to eavesdrop on the signal representing measured aortic blood pressure such that information representing measured aortic blood pressure is sent to the receiver while allowing the central monitoring device to receive and use the signal representing measured aortic blood pressure.

Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are provided. The data can be displayed on a hand-held display device having a display such as a key fob device including a user interface, such as an LCD and one or more buttons allows a user to view data, and a physical connector, such as USB port.

Abstract: A device for measuring the elasticity of a macroscopic sample, in particular for measuring the elasticity of tissue of a living human or animal, is disclosed, which comprises the following: at least one outlet for a jet of fluid and/or one inlet for aspiration of a stream of fluid, means for positioning the device in relation to the macroscopic sample in such a way that the outlet and/or the inlet and/or an end face of the device is at a predetermined distance from the macroscopic sample, or at a distance therefrom that can be determined by said means, and a mechanism for measuring a variable that is characteristic of the extent of a deformation of the sample on account of an interaction of the sample with the jet of fluid and/or the aspirated stream of fluid, wherein this variable is determined by an ion current in the deformation area of the sample, or the volumetric flow of the fluid itself, or, if the fluid is enclosed by the elastic sample, by a change of volume and associated change of pressure in the e

Abstract: The invention provides a polarized optical system with minimal use of wave plates that provides isolation of the optical source and has optimized signal to noise performance. The polarized optical system in the preferred embodiment is an interferometric optical system, and in particular an optical coherence tomography (OCT) system. Various alternate embodiments are provided.

Abstract: A fluorescent image acquisition and projection method includes the steps of generating, by a plurality of light sources, invisible fluorescence under control of a control device and obtaining, by a detection unit, a signal of an invisible fluorescent image from a target object. The method further includes the steps of receiving from the detection unit and processing the invisible fluorescent image signal of the target object into a visible fluorescent signal, transmitting the visible fluorescent signal to a projector unit, and projecting, by the projector unit, the visible fluorescent signal onto the target object.

Abstract: The shape of the urine stream can be used to measure both the flow rate and orifice geometry. The measurement of the shape of the urine stream can be a useful diagnostic tool for medical practitioners since it provides a noninvasive method of measuring urine flow rate and urethral dilation. A novel diagnostic visual voiding device (VVD) measures Symptoms of Lower Urinary Tract Dysfunction (LUTD) such as urinary incontinence. The VVD consists of a lightweight foldable booth with LED lights, microphone, video cameras on left side, top, face, and container that display stream height, width, angle, distance, face grimacing, container height and flow versus time. The VVD will improve the initial diagnosis of Lower Urinary Tract Dysfunction (LUTD) and also improve LUTD by providing subsequent diagnosis after treatment. It enables the patient to video and audio record urinary voiding in privacy.

Abstract: Apparatus and methods for determining a type of a material in a region within a vascular system of a patient and/or a distance to the material are provided. At least one source fiber is provided that supplies light from a light source to a region within a vascular system of a patient. At least one return fiber is provided to receive light reflected from the region within the vascular system. At least one controller is provided to determine at least one property of the region within the vascular system from the reflected light, and to determine a type of a material in the region within the vascular system and/or an indication of a distance to the material. Techniques such as laser ablation may then be performed based on the determined material type and/or distance to remove unwanted buildup, deposits, etc., while avoiding harmful results such as tearing of tissue.

Abstract: A calibrator calibrates optical characteristics of an optical measurement apparatus in water by inserting a measurement probe connected to the optical measurement apparatus into the calibrator. The optical measurement apparatus is configured to perform optical measurement on body tissue. The calibrator includes: an accommodation portion that has an opening at one end thereof and accommodates the water, a distal end of the measurement probe being configured to be inserted into the accommodation portion; and a removing unit that is arranged in the water and is configured to remove a substance adhered to the distal end of the measurement probe inserted into the accommodation portion.

Abstract: A photoacoustic apparatus that improves absorption coefficient measurement accuracy by obtaining information on a subject after performing correction in accordance with amounts of light emitted to the subject includes a photoacoustic wave detection unit that detects photoacoustic waves generated from a subject when a light source irradiates the subject with light and output detection signals and a signal processing unit that performs signal processing to obtain information on the subject in accordance with the detection signals. The signal processing unit obtains information on the subject after performing correction in accordance with amounts of light emitted to the subject.

Abstract: The present system is directed in various embodiments to methods, devices and systems for sensing, measuring and evaluating compliance in a bodily conduit. In other embodiments, the methods, devices and systems sense, measure, determine, display and/or interpret compliance in a bodily conduit and/or a lesion within the bodily conduit. In all embodiments, the sensing, measuring, determining, displaying and/or interpreting may occur before, during and/or after a procedure performed within the bodily conduit. An exemplary conduit comprises a blood vessel and an exemplary procedure comprises a vascular procedure such as atherectomy, angioplasty, stent placement and/or biovascular scaffolding.

Abstract: The present system is directed in various embodiments to methods, devices and systems for sensing, measuring and evaluating compliance and/or elastance in a bodily conduit. In other embodiments, the methods, devices and systems sense, measure, determine, display and/or interpret compliance and/or elastance in a bodily conduit and/or a lesion within the bodily conduit using fractional flow reserve and/or flow velocity measurements as well as resistance to flow calculations in certain embodiments. In all embodiments, the sensing, measuring, determining, displaying and/or interpreting may occur before, during and/or after a procedure performed within the bodily conduit. An exemplary conduit comprises a blood vessel and an exemplary procedure comprises a vascular procedure such as atherectomy, angioplasty, stent placement and/or biovascular scaffolding.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example system for mapping the electrical activity of the heart includes a catheter shaft. The catheter shaft includes a plurality of electrodes including a first electrode and a second electrode. The system also includes a processor. The processor is capable of collecting a first signal corresponding to the first electrode and a second signal corresponding to the second electrode. Collecting the first and second signals occurs over a time period. The processor is also capable of generating a first time-frequency distribution corresponding to the first signal, identifying a first dominant frequency value occurring at a first dominant frequency and a first time point, generating a second time-frequency distribution corresponding to the second signal, identifying a second dominant frequency value occurring at a second dominant frequency and a second time point and determining an attraction point.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example system for mapping the electrical activity of the heart includes a catheter shaft. The catheter shaft includes a plurality of electrodes including a first and a second electrode. The system also includes a processor. The processor is capable of collecting a first signal corresponding to a first electrode over a time period and generating a first time-frequency distribution corresponding to the first signal. The first time-frequency distribution includes a first dominant frequency value representation occurring at one or more first base frequencies. The processor is also capable of applying a filter to the first signal or derivatives thereof to determine whether the first dominant frequency value representation includes a single first dominant frequency value at a first base frequency or two or more first dominant frequency values at two or more base frequencies.

Abstract: A method of identifying a predetermined type of abnormal movement of a physical object includes generating a raw matrix comprising a first array and a second array, the generation of the raw matrix. The method also includes generating an integrated matrix by performing a dimension reduction on the raw matrix. The method a further includes identifying the predetermined type of abnormal movement of the physical object by comparing the integrated matrix or a set of indexes derived from the integrated matrix with a predetermined benchmark pattern corresponding to the predetermined type of abnormal movement. Generating the raw matrix includes a first analysis on a predetermined portion of a periodic signal representative of movement of the physical object to generate the first array. Generating the raw matrix also includes performing a second analysis different from the first analysis on the predetermined portion of the periodic signal to generate the second array.

Abstract: A biometric authentication apparatus and method are provided. The biometric authentication apparatus may obtain at least two types of biosignals, extract a same type of physiological features from each of the biosignals, and determine whether the biosignals are generated from a same living body based on the extracted same type of physiological features.

Abstract: In one aspect, a photoplethysmograph system to measure a user's heart rate includes one or more light-emitting diodes (LED) that provide a constantly-on light signal during a measurement period. The one or more light-emitting diodes are in optical contact with an epidermal surface of the user. The one or more light-emitting diodes emit a light signal into the tissue of the user, and wherein the tissue contains a pulsating blood flow. A light-intensity sensor circuit converts the reflected LED light from the tissue into a second signal that is proportional to a reflected light intensity. The second signal includes a voltage or current signal. A computer-processing module calculates the user's beat-to-beat heart rate from the second current signal.

Abstract: An MRI system and method for dynamic susceptibility contrast (DSC) imaging use multiplexed echo planar imaging (M-EPI) to essentially simultaneously acquire MR signals for perfusion parameter images of multiple slices. This essentially simultaneous acquisition of MR signals for multiple slices can be repeated in rapid succession without deteriorating T2* contrast, which makes it practical to image multiple perfusion phases and brings about other significant benefits.

Abstract: The invention provides various methods of identifying myocardial infarction (MI) patients who have microvascular obstruction (MO), persistent microvascular obstruction (PMO), reperfusion hemorrhage, iron deposition, chronic iron deposition, and/or fat infiltration/accumulation. The invention provides various methods of identifying myocardial infarction (MI) patients who are at risk of prolonged inflammation burden in heart, adverse cardiac remodeling, electrical abnormality, mechanical abnormality, malignant cardiac arrhythmia, ischemic heart failure, and/or sudden cardiac death. The invention also provides various methods of treating these MI patients with chelation drugs, anti-inflammatory drugs, fat-lowering drugs, cooling therapies, or device therapies, or their combinations.

Abstract: Adaptive attachments used in combination with a blood pressure cuff enable various blood pressure measurements to be taken in a hospital or other setting having various single and/or dual lumen manual or electronic blood pressure measuring equipment with a single, patient-worn cuff.

Abstract: Provided is an apparatus and method of measuring a pulse wave. The method includes: causing receivers to respectively receive pulse wave signals that are detected at two points of an object, determining an effective pulse wave signal period by using the received pulse wave signals, and obtaining a pulse transit time (PTT) between the two points by using a result obtained after comparing a magnitude of an output signal of each of the receivers with a value that is less by a predetermined percentage than a peak value of an output signal of each of the receivers during the determined effective pulse wave signal period.

Abstract: One innovative aspect is directed to heartrate data collection. In some implementations, a circuit includes a light detector for generating a detected signal based on received light. The circuit includes a switching circuit configured to receive a first signal based on the detected signal and to switch among a first and a second configuration. In some implementations, the circuit includes a first and a second sampling circuit for sampling a value of the first signal when the switching circuit is in the first configuration and second configurations, respectively. In some implementations, the circuit includes an ambient light cancellation circuit for countering a first component of the first signal while the first switching circuit is in the first configuration. In some implementations, the circuit includes an adjustable gain circuit for adjusting a gain of the first signal while the first switching circuit is in the first configuration.

Abstract: Sensing Foley catheter variations are described herein which may comprise a fluid chamber defining a receiving channel and a port fluidly coupled to a drainage lumen of the catheter such that the receiving channel is in fluid communication with the drainage opening. A pressure sensing mechanism located within the fluid chamber may comprise a pressure sensing mechanism which is configured to detect fluid pressure when body fluid, such as urine, is introduced into the drainage opening of the catheter and is received within the receiving channel and impinges upon the pressure sensing mechanism.

Abstract: This disclosure relates generally to medical devices, particularly to drawer-type paper tray structures for loading paper into electrocardiograph machines. A paper tray structure provided comprises a paper tray and a door component. The door component comprises a door located in front of the paper tray. The door component is connected to the paper tray movably and is configured to move repeatedly between a first position and a second position relative to the paper tray; the paper tray comprises a first restriction surface and a second restriction surface corresponding to the first and second positions respectively.

Abstract: The instant disclosure relates generally to a tip electrode for delivering irrigant to a distal portion of the tip electrode and irrigated catheter tips incorporating such a tip electrode. The distal portion of the tip electrode can have additional fluid ports on the distal edge of the tip to provide additional fluid flow to that region.

Abstract: The present disclosure uses physiological data, ECG signals as an example, to evaluate cardiac structure and function in mammals. Two approaches are presented, e.g., a model-based analysis and a space-time analysis. The first method uses a modified Matching Pursuit (MMP) algorithm to find a noiseless model of the ECG data that is sparse and does not assume periodicity of the signal. After the model is derived, various metrics and subspaces are extracted to image and characterize cardiovascular tissues using complex-sub-harmonic-frequencies (CSF) quasi-periodic and other mathematical methods. In the second method, space-time domain is divided into a number of regions, the density of the ECG signal is computed in each region and inputted into a learning algorithm to image and characterize the tissues.

Abstract: A method for attaching a split ring electrode to a catheter tip section includes providing a tubing with a lumen and an opening in the tubing side wall, passing an electrode lead wire through the opening, and wrapping the lead wire around the tubing. A split ring electrode is mounted on the tubing over the wrapped lead wire and opening, with electrically-conductive thermoplastic elastomeric adhesive applied between the ring electrode and the outer surface of the tubing, and reheated to reflow.

Abstract: A method and system for visualization of electrophysiology information sensed by electrodes on a catheter, includes recording times of electrode signal acquisition, designating a reference electrode signal acquisition, assigning a relative time to each recorded time of electrode signal acquisition relative to the reference electrode signal acquisition, identifying the electrodes with signal acquisition, correlating assigned relative times to identified electrodes to generate a sequence of electrode signal acquisitions, and generating a visual representation of the sequence of electrode signal acquisitions generating a visual representation with a graphical image of the electrodes, wherein individual electrodes are visually marked to represent the sequence of electrode signal acquisitions.

Abstract: A multi-device connector for ECG signals permits multiple medical devices to share patient-connected surface electrodes, providing a patient-side terminal set having a direct connection to one device-side terminal set and buffered connections to multiple additional device-side terminal sets. Invasive blood-pressure sensor readings may also be shared by providing a direct connection between a patient-side terminal set and multiple device-side terminal sets for blood-pressure signals and a direct connection between the patient-side terminal set and only one device-side terminal set. Indirect, scaled connections between the remaining device-side terminal sets and the patient-side terminal set may be provided.

Abstract: The system and method of the present application selects and presents ECGs that are most important to the user in conjunction with a measurement trend that relates to the diagnosis and management of the abnormality. In addition, the system and method of the present application will guide the user to verify whether the ECGs selected by the computer were valid and if not guide the user through measurement trends to find 12-ECGs of significance.

Abstract: A method of analyzing electrocardiograph (ECG) data includes receiving a first representative ECG of a patient and isolating a first principal component, a second principal component, and a third principal component of the first representative ECG. The principal components are isolated by selecting a portion of the first representative ECG relating to depolarization, calculating a covariance matrix based on the portion of the first representative ECG, conducting a principal component analysis of the covariance matrix, and selecting a first component of the principal component analysis as the first principal component, the second component of the principal component analysis as the second principal component, and the third component of the principal component analysis as the third principal component. A depolarization subspace is then formed based on the first principal component, second principal component, and the third principal component of the first representative ECG.

Abstract: An electronic apparatus for establishing prediction model based on electroencephalogram (EEG). The electronic apparatus is configured for: acquiring an EEG signal segment related to an epilepsy patient; dividing each EEG signal into EEG components according to a predetermined window size; retrieving datasets corresponding to EEG features from the EEG components of each EEG signal segment; acquiring statistical feature values of each dataset of each EEG signal segment; determining a gain ratio of each of the statistical feature values of each EEG signal segment based on the statistical feature values corresponding to each of the EEG features; selecting specific statistical feature values from the statistical feature values according to the gain ratio of each of the statistical feature values of each EEG signal segment; establishing a prediction model based on the specific statistical feature values of the epilepsy patient.

Abstract: This document provides methods and materials related to the non-invasive measurement of analytes in blood.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example system for mapping the electrical activity of the heart includes a processor. The processor is capable of sensing a plurality of signals with a plurality of electrodes positioned within the heart and collecting a plurality of signals corresponding to the plurality of electrodes. Collecting the plurality of signals occurs over a time period.

Abstract: The invention relates to a bio-medical electrode (100). In a preferred embodiment, an electrode interface comprises a top part (10) with an aperture and a bottom part (20). The bottom part (20) has a head portion designed for a fixation in said aperture and a flexible flange that clamps electrode sheets (31,32) in the connected state of the electrode interface such that the contact force between top and bottom parts is approximately constant during lifetime of the electrode interface. The top part (10) may preferably have the shape of a disk of magnetic or magnetizable material. The bottom part (20) may preferably be made from a conductive plastic such as ABS. The electrode interface may particularly be used in a TENS device.

Abstract: A system automatically detects and measures ST deviation of a heart wave ECG signal in the presence of noise and accommodates baseline variation of the signal and other artifacts. A system identifies a particular point in an electrophysiological signal representing heart electrical activity using an interface for receiving an electrical signal waveform comprising an R-wave and including an ST segment portion associated with heart electrical activity of a patient over a heart beat cycle. A signal processor processes data representing the electrical signal waveform by identifying an S point and T point in the electrical signal waveform and determining a first candidate J point in the electrical signal waveform having substantially a maximum distance from a line between the identified S and T points, the distance being measured perpendicularly to the line.

Abstract: A method is disclosed for displaying patient ECG data. The method includes receiving ECG data including an ECG waveform; receiving analyzed ECG data including arrhythmic events; generating an indicia of the detected arrhythmic event; and displaying the indicia of the detected arrhythmic event in relation to the ECG waveform at a position associated with a time of the detected arrhythmic event. A system for displaying patient ECG data is also disclosed.

Abstract: The present disclosure provides a semi-contact type ECG measurement system, comprising a contact-type sensor configured to directly contact a skin of a passenger in a vehicle and detect a first ECG signal; a non-contact type sensor configured to be in proximity to the passenger to detect a second ECG signal without directly contacting the skin of the passenger; and an ECG sensor module configured to process the first and second ECG signals and configured to determine a biological status of the passenger from the first and second ECG signals microcontroller.

Abstract: A wearable remote electrophysiological monitoring system. The system includes a garment having at least one nanostructured, textile-integrated electrode attached thereto; a control module in electrical communication with the at least one nanostructured, textile-integrated sensor, and a remote computing system in communication with the control module.

Abstract: A wireless patient monitor comprises a generic activator module having a universal connection port that connects with any one of multiple sensor devices, a battery, and a radio transmitter wirelessly connected to a host device. The generic activator module connects to any one of multiple sensor devices via the universal connection port to provide power from the battery to the sensor device and to receive digital physiological data from the sensor device. The radio transmitter transmits the digital physiological data received from the sensor device to a host device.

Abstract: This invention detects tissue injury using microcurrent. Repeated tests, standardized with the force gauges will show significantly decreased microcurrent over injured tissue. It is fast, simple, and inexpensive, and directly measures tissue injury.

Abstract: A medical probe, including a flexible insertion tube having a distal end for insertion into a body cavity. An array of spatially separated coils is positioned within the distal end. A processor is configured to process respective signals generated by the coils in response to magnetic resonance of tissue in the body cavity, and to process the signals while applying a phase delay responsive to a separation between the coils so as to image the tissue.

Abstract: The invention provides a device for detecting non-cavitated caries lesions, including a measuring electrode having an electrically conductive tip. The tip is dimensionally configured to fit within a fissure and provide electrical contact with a patient's tooth. A reference electrode is also included, the reference electrode being configured for electrical contact with the patient's body. A measuring means is also provided for determining electrical conductance between the measuring electrode and the reference electrode, wherein the device is further configured to receive a current source for providing electrical current between the measuring electrode and the reference electrode.

Abstract: A method and apparatus of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measuring spectrum of alternating current (or voltage) produced in the second of the induction coils (or antennae); and comparing the phase shift between the spectrum of alternating currents (or voltages) in the first and second induction coils (or antennae), thereby determining the condition of the bulk tissue sample.

Abstract: A method of guiding an interventional instrument within a patient anatomy comprises processing a target location within the patient anatomy and receiving a position for a tip portion of an interventional instrument at a first location within the patient anatomy. The method also comprises determining a three-dimensional distance between the first location and the target location and displaying a symbol representing the target location and a symbol representing the tip portion of the interventional instrument.

Abstract: A system and surgical procedure for monitoring physiological parameters within an internal organ of a living body. The procedure entails making a first incision to expose the organ and a second incision through an external wall of the organ and into an internal cavity. A sensing unit is placed in the second incision such that a proximal end thereof remains outside the organ. The unit includes a sensing device having a sensing element for sensing the physiological parameter within the organ, and an anchor to which the sensing device is secured. The unit occludes the second incision and a distal end of the unit does not extend more than one centimeter into the cavity. The anchor is then secured to the wall of the organ, after which the first incision is closed and a readout device telemetrically communicates with the sensing device to obtain a reading of the physiological parameter.

Abstract: A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals.

Abstract: A laser catheter with a pressure sensor is provided according to embodiments of the invention. The pressure sensor may be coupled with the distal end of the laser catheter and may comprise any of various piezoelectric materials, for example Polyvinylidene Difluoride (PVDF). In various embodiments of the invention the pressure sensor is configured to detect pressure longitudinally and coaxially. The pressure sensor may provide an electric potential that is proportional to the vessel pressure and may be used to monitor and/or adjust laser parameters. In other embodiments the results from the pressure sensor may be used to determine the vessel size and/or the type of material being ablated.