Abstract: The present invention generally relates to methods for providing darkness therapy for altering biological rhythms. Specifically, embodiments of the present invention are directed to the process of employing an optical device configured to block certain wavelengths of light while allowing other wavelengths to pass through in order to provide significant biologically therapeutic effects. These and other advantages are detailed further herein.

Abstract: A catheter that prevents excessive concentration of stress while providing sufficient flexibility to a distal end portion of the catheter, even when the catheter is inserted and curved in patient's a blood vessel. Thus, breakage of the catheter at a radiopaque marker is prevented/reduced. The catheter includes a catheter tube and the radiopaque marker, which is disposed in the catheter tube. The radiopaque marker is fixed in the catheter so that a gap is provided between the radiopaque marker and the catheter tube in a radial direction of the catheter tube.

Abstract: A catheter has a proximal portion of relatively larger central lumen diameter and outer diameter, and a distal portion of relatively smaller central lumen diameter and outer diameter, the two portions being integral with one another so that cells delivered into the central lumen of the proximal portion will flow through and exit the central lumen of the distal portion, encountering a constriction at the junction of the two portions, for infusion into body tissue at a predetermined target site when the catheter is inserted into a designated natural body vessel or duct leading to the target site. The cells are delivered in a fluid under pressure through a central lumen of the catheter to exit distally from the lumen at the target site, and meander of exiting fluid pressure from a predetermined value is minimized by adjusting the fluid pressure at the point of entry into the catheter's central lumen accordingly.

Abstract: A device for implantation or insertion into the human body, and to a set with the device and a stylet. In order to be able to change the flexibility of the device, the device includes a pair of stiffening elements that can be affixed to and detached from each other.

Abstract: An antimicrobial lubricant applied to an outer surface of an introducer needle as part of a catheter assembly device. The catheter assembly device further includes a blood control septum having a slit through which the introducer needle is threaded. The antimicrobial lubricant is squeegeed, or removed from the outer surface of the introducer needle as the needle is removed from the slit following catheterization. The removed antimicrobial lubricant forms a deposit on the septum at a location proximate to the slit, thereby preventing colonization and growth of pathogens on the septum and other adjacent components and surfaces of the catheter assembly device.

Abstract: A catheter proximal section is preferably formed from a relatively soft part and a relatively rigid part, and includes a proximal terminal end that defines a perimeter of an opening into a lumen of the catheter. The proximal section may further include a feature for interlocking engagement with an accessory tool. An inner surface of each of the relatively soft and rigid parts may be located opposite one another, on either side of the catheter lumen. The relatively soft and rigid parts may be included in a sealing assembly that further includes an attachment feature for removable connection of the assembly to the proximal section catheter.

Abstract: An instrument driver comprises a base and a jaw assembly coupled to the base. The jaw assembly includes a first jaw having a gripping surface and a second jaw having a gripping surface. The instrument driver further comprises a driver assembly operably coupled to the jaw assembly to advance an elongated member relative to the base by translating the first and second jaws toward each other, thereby closing the jaw assembly and gripping the member between the respective gripping surfaces of the first and second jaws, translating the jaw assembly in a first axial direction when the jaw assembly is closed, translating the first and second jaws away from each other, thereby opening the jaw assembly and releasing the member from between the respective gripping surfaces of the first and second jaws, and translating the jaw assembly in a second axial direction when the jaw assembly is opened.

Abstract: A deflectable catheter including an outer member having a proximal portion and a distal portion, an elongated column member extending distally from the outer member and an inner member positioned coaxial with the outer member and attached to the column member. The inner member extends distally of the outer member and has a distal tip portion. A reinforcement member is positioned over the column member to restrict axial movement of the column member such that when one of the inner member or outer member is moved with respect to the other, axial compression of the column member is restricted by the reinforcement member causing the distal tip portion of the inner member to deflect laterally.

Abstract: A catheter for use with a subintimal reentry guidewire includes a proximal portion having a proximal guidewire lumen and a proximal inflation lumen, a distal portion having a distal guidewire lumen and a distal inflation lumen, and an intermediate portion disposed between the proximal portion and the distal portion and having an intermediate inflation lumen in fluid communication with the proximal and distal inflation lumens. The intermediate portion is devoid of a guidewire lumen. A blocking mechanism disposed in the distal portion of the catheter is transformable from a non-blocking configuration in which a guidewire is free to translate through the distal guidewire lumen and a blocking configuration in which a guidewire disposed in the distal guidewire lumen is prevented from translating through the distal guidewire lumen.

Abstract: An intravenous (IV)catheter apparatus comprising: a tubular catheter (10) having a proximal end (50) and a distal end (16) mounted to a catheter hub (40); a needle (12) defining an axial direction (A) having a needle shaft (22) with a needle tip (14) at a distal end (16) and a needle hub mounted to the proximal end (50) of the needle shaft (22); a needle guard (30) arranged movably on the needle shaft (22), wherein said needle shaft (22) extends through said tubular catheter (10) such that said needle tip (14) of said needle (12) protrudes from said distal end (16) of said tubular catheter (10); and wherein said needle shaft (22) is provided with: an engagement means (26) adapted to engage with the said needle guard (30) in order to prevent said needle guard (30) from sliding off said needle tip (14); and one or more lateral openings (28) covered by said tubular catheter (10).

Abstract: Provided are a pancreas perfusion apparatus capable of administering a drug only to the pancreas and strictly suppressing a leakage of the drug outside the pancreas and a method for controlling the same. The apparatus includes: a first vein occlusion section occluding a vein through which a venous blood from the pancreas flows; a second vein occlusion section occluding a vein into which a venous blood from collateral pathways outside the pancreas flows; an artery occlusion section occluding sites where an artery that nourishes the pancreas is connected to arteries that nourish other tissues; a drug administration section recovering a liquid upstream of the first vein occlusion section and supplying the recovered liquid to the artery; a systemic circulation section recovering a liquid upstream of the second vein occlusion section and feeding the recovered liquid into a systemic circulation; and a control device controlling the systemic circulation pump.

Abstract: A siphon guard includes a housing having an inlet and an outlet. A primary flow path is disposed within the housing and is in fluid communication with the inlet and the outlet. A secondary flow path is disposed within the housing and is in fluid communication with the inlet and the outlet. The secondary flow path has a higher resistance to fluid flow than the primary path. A valve is disposed within the primary flow path. The valve has a valve seat and a first ball and a second ball. The first ball is movable by gravity between a valve closed position, where the first ball is in contact with the valve seat, and a valve open position, where the first ball is spaced from the valve seat. The first ball is disposed between the second ball and the valve seat. The second ball is movable by gravity between a valve closed position and a valve opened position.

Abstract: Technology disclosed herein provides a reduced transition between the edge of a rigid vascular dilator and the distal edge of the accompanying introducer sheath. Disclosed dilators can be segmented into two or more primarily longitudinally extending parts, can have rigid circumferential or semi-circumferential leading shoulders to minimize the transition between the dilator and the sheath edge, and can contain internal recesses to allow sequential retraction of segments once the introducer sheath is delivered to a target chamber. With this technology, vascular introducer sheaths can be introduced percutaneously into a broad range of diseased target vessels and chambers with reduced damage to the wall of the vessel or chamber, and with reduced damage to the distal end of the introducer sheath.

Abstract: A hemostatic equipment has a pallet and an inflatable pillar. The pallet has a holder used for a patient to hold, providing foolproof effect in an operation direction to ensure that the inflatable pillar may enter a nasal cavity of a patient in a correct direction. The inflatable pillar has a head exposed with a pressing surface for pressing a bleeding site inside a nasal cavity of a patient to stop bleeding.

Abstract: An apparatus for cleansing and promoting tissue growth in wounds, in which irrigant fluid optionally containing cell nutrients and/or other physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing, a biodegradable scaffold in contact with the wound bed and a means for fluid cleansing and back to the dressing. The apparatus has means for supplying thermal energy to the fluid in the wound. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus.

Abstract: A temporary disposable spacer device implantable in the human body for treatment of an infected bone seat or a joint seat includes a body provided with at least one coupling surface to the bone seat or joint seat to be treated and recesses along the coupling surface.

Abstract: Certain embodiments according to the present invention provide sleeve devices suitable for a wide range of therapeutic uses. In accordance with certain embodiments, the therapeutic sleeve device includes a nanofiber fabric assembly, which defines a plurality of pores, and at least one layer of cells embedded in the nanofiber fabric assembly.

Abstract: An assembly includes a patch including a substance adapted for transdermal delivery, and a driver operative to move the patch to one or more of a plurality of operational relationships with a skin of a patient, including being in full contact with the skin, partial contact with the skin, and no contact with the skin.

Abstract: Provided is a device for surely and easily applying a microneedle patch to a skin. In a case body 2, a pressing member 3 having a tip surface 3a is disposed such that the pressing member is biased in a first direction X1 by a first biasing member. The movement in the first direction X1 is locked by a locking member 7 and a locking part 3g so that the pressing member 3 is brought into a locked state. The locked state is released by pressing a tip of a lock-releasing member 11 against the skin. When the locked state is released, a tip surface 3a of the pressing member 3 is moved in the first direction X1 and the tip surface 3a applies the microneedle patch to the skin.

Abstract: A device for puncturing a heparin cap is disclosed, including: a connecting unit, adapted to be coupled to a medicinal fluid supply device in fluid communication; a guiding unit, adapted to accommodate at least one part of the heparin cap; and a puncturing unit for puncturing the heparin cap, configured to be in fluid communication with the connecting unit and at least partially located on a predetermined position in the guiding unit. The predetermined position is configured so that in the process of at least one part of the heparin cap entering into the guiding unit, the puncturing unit is inserted into a sealing rubber of the heparin cap at an appropriate location on the heparin cap and an appropriate angle relative to the heparin cap, and ultimately penetrate through the sealing rubber. With the device, the medical worker can complete the puncture of the heparin cap safely, easily and effectively.

Abstract: A skull implant medication injection port comprises: a mounted portion placed on an upper section of a port insertion hole in a patient's cranium and a medication inlet on a top surface; a medication injection diaphragm that seals the medication inlet of the mounted portion where a needle for injecting a medication is inserted; a medication storage portion coupled with a bottom of the mounted portion stores the medication injected through the medication injection diaphragm; a medication discharge pipe connected to the medication storage portion discharges the medication stored in the medication storage portion; and a rib formed on a perimeter between the mounted portion and the medication storage portion that has a diameter larger than an inner diameter of the port insertion hole. A height of the mounted portion is generally about 4 to 7 mm, and a height of the medication storage portion is generally about 2 to 4.2 mm.

Abstract: The needle-free connector (1) for an infusion line comprises: a containment body (4) which can be coupled to the line, comprising an entry (7) and an internal pipe (8, 17) suitable for the fluid-dynamic communication with the entry (7) and with the line; and a sealing element (14) suitable for moving between an occlusion position wherein it seals the entry (7) and an opening position wherein it frees the entry (7); wherein the connector (1) is constituted by two members which are the body (4) and the sealing element (14), each of which is made in a single body piece.

Abstract: The invention discloses a connector (1) for substantially aseptic connection of tubing, comprising: a) a central tubular stem member (2) with a line connection end (3) and a coupling end (5) having an annular gasket (6) arranged to engage a similar annular gasket (26) on a similar second connector (21) in sealing abutment and; b) a tubular socket member (7), concentrically arranged outside the stem member, having a flange (8) concentrically arranged outside the coupling end and comprising a cover film (9) releasably bonded to the flange and covering the coupling end of the stem member, the annular gasket and at least a portion of the flange; wherein the socket member is rotatable around the stem member and wherein the connector further comprises an annular seal member (10) in sealing abutment between an inside (11) of the socket member and an outside (12) of the stem member.

Abstract: A urine control device to be placed intermediate a catheter and a collection bag is provided. The urine control device includes first and second bell shaped housings with a magnetic valve disposed between the first and the second housings. When the pressure from the urine which flows through the present catheter enters the first chamber and exceeds the magnetic attraction in the valve, the valve pivotally opens, permitting the urine to flow through the open valve and into the second chamber. Due to the shape of the chambers, secondary forces create a low pressure zone in the second chamber which helps empty the bladder fully. Once the flow ceases, the magnetic valve pivotally shuts, allowing the urine pressure to build once again. Various sample ports and air entry ports may be provided on the device.

Abstract: An implantable lead connector configured for long term implantation and to electrically interconnect multiple medical devices and to channel electrical signals between said interconnected devices and a target organ, comprising: a first port adapted to receive a first signal suitable to stimulate a target tissue, a second port adapted to receive a second signal suitable to stimulate a target tissue, and a third port configured to connect to a target organ, wherein at least one of said first and second ports is configured to connect to a signal generator not integrated with said connector.

Abstract: Described herein is an apparatus and method for ischemic muscle training or recovery by coordinated blood flow restriction and electrical muscle stimulation. The apparatus comprises a blood flow occluding element for restricting blood flow to a target muscle or muscle group in a user, and measuring resting systolic blood pressure (SBP); and an electrical muscle stimulator comprising at least one electrode and a control unit which, upon activation, is effective to send low amplitude electric pulses through the target muscle or muscle group forcing the targeted muscle to contract while the blood flow is restricted.

Abstract: An implantable lead includes a lead body having a proximal end portion and a distal end portion. The lead body includes an insulative member having a lumen extending longitudinally between the proximal end portion and the distal end portion. The lead body also includes a generally tubular helical liner disposed coaxially with the lumen within the insulative member. A pitch of the helical liner varies along the length of the lead. The implantable lead also includes an electrode disposed along the lead body in the distal end portion thereof, and a conductor disposed within the lumen and electrically coupled to the electrode. A terminal connector is coupled to the proximal end portion of the lead body and to the conductor.

Abstract: A microlead, of an overall diameter less than 0.5 mm, includes a plurality of at least eight conductor wires individually insulated and twisted together. Each conductor wire includes an electrically conductive core microcable and an insulation layer surrounding the core microcable and having at least one exposed area to form a detection/stimulation electrode of the microlead. The microlead further includes a central support structure shaped as a surface of revolution, which may be free of conductor wires and of central lumen. The conductor wires are configured in one or more layers of twisted peripheral conductor wires carried by the central support structure and circumferentially distributed thereon.

Abstract: Embodiments of the present invention generally pertain to devices and methods for use in conjunction with implanting a baroreflex therapy system which includes an implantable pulse generator and associated circuitry contained within a hermetically sealed housing, an elongate flexible electrical lead connectable to the housing, and a monopolar electrode structure coupled with the electrical lead. More specifically, the devices and methods of the present invention allow for a mapping procedure to be conducted as part of the implant procedure prior to fully implanting the baroreflex therapy system.

Abstract: Example adjustable electrodes are described. One example adjustable electrode includes two or more contacts configured to selectively deliver high frequency alternating current (HFAC) to a nerve in an amount sufficient to produce an HFAC nerve conduction block in the nerve. The example adjustable electrode may also include a logic configured to selectively control which of the two or more contacts deliver HFAC to the nerve to control whether the nerve electrode is in a first (e.g., onset response mitigating) configuration or in a second (e.g., HFAC nerve conduction block maintenance) configuration. The electrode may be used in applications including, but not limited to, nerve block applications, and nerve stimulation applications. The electrode may be adjusted by changing attributes including, but not limited to, the number, length, orientation, distance between, surface area, and distance from a nerve of contacts to be used to deliver the HFAC.

Abstract: A medical electrical lead having an elongated lead body and a fixation helix extending along a generally helical axis, mounted around the outer circumference of the lead body. The fixation helix has a free end spaced from and extending from the lead body for less than the circumference of the lead body. The lead body includes an additional component which provides a rotation stop extending from the outer circumference of the lead body and provides stop surface generally perpendicular to the axis of the helix.

Abstract: A system for delivering an implantable medical device includes a loading assembly and a catheter. The loading assembly includes a deployment member and a sidewall defining a chamber into which the device may be pulled through a distal opening thereof, so that the sidewall holds fingers of the device's fixation member in an extended condition while a temperature in the chamber is lowered. When the chamber is connected to the catheter, advancing the deployment member pushes the device, with fixation fingers in the extended condition, into a delivery lumen of the catheter. With the catheter positioned within a patient, the device can be pushed into a distal portion of the catheter while a relatively cold fluid is infused through the delivery lumen. While holding the deployment member in place, retracting the catheter exposes the device fixation fingers out from the lumen, for engagement with tissue at the implant site.

Abstract: An electrode for use with an implantable medical device includes an alloy and a conductive oxide layer on a surface of the alloy. The alloy includes iridium and at least one of cobalt and iron. The conductive oxide layer includes iridium oxide. The conductive oxide layer has a thickness greater than about 5 nanometers.

Abstract: A medical access tool includes a needle member extending along a longitudinal axis, and a coiled wire extending around the axis. An inner surface of the coiled wire, along a proximal segment thereof, is spaced radially apart from an outer surface of the needle member, and a distal segment of the coiled wire extends distally to a tissue-engaging tip of the coiled wire, a piercing distal tip of the needle member being recessed proximally from the tissue-engaging tip at a fixed distance. An operator may rotate the coiled wire to engage tissue, for example, that of a pericardial sac or a diaphragmatic attachment, which then travels proximally along the coiled wire and into contact with the needle member's distal tip, to be pierced through thereby. At least one lumen of the needle member provides a passageway through which the operator may advance a guide wire and/or inject a fluid.

Abstract: A device and method to inhibit growth of cancer cells is disclosed. The device may include a power source and an electric field generator. The power source may output an electric potential to cause an electric field to be emitted from the electric field emitter and be applied to target tissue, which may include cancer cells.

Abstract: The present invention relates to a portable iontophoretic system using a sheet mask, particularly the portable iontophoretic system which has a current-carrying part for a metal contact formed on a side surface of a portable iontophoresor and enables iontophoresis to be carried out on the skin when a user holds the current-carrying part in a state of the disposable sheet mask applied on a user's skin by connecting the disposable sheet mask to the iontophoresor with a tong, thereby providing an efficient skin care effect through a simple structure.

Abstract: The present invention relies on a controller-transmitter device to deliver ultrasound energy into cardiac tissue in order to directly improve cardiac function and/or to energize one or more implanted receiver-stimulator devices that transduce the ultrasound energy to electrical energy to perform excitatory and/or non-excitatory treatments for heart failure. The acoustic energy can be applied as a single burst or as multiple bursts.

Abstract: In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects.

Abstract: A device positioned in the vagina includes a sensor. The sensor data is used to determine whether a condition is met or exists to trigger a therapeutic response by the device. A device for stimulating nerves adjacent the vagina includes a nerve stimulating element coupled to a main body. The nerve stimulating element is positioned and designed to stimulate the vesical, Frankenhauser's and/or inferior hypogastric plexuses. The device may reside in the vaginal fornices. An implant is also provided which has a nerve stimulating element in contact with a uterosacral ligament. The device positioned in the vagina may be used to charge a power source for an implant, which may be a capacitor.

Abstract: Systems and methods for producing cervical ripening in a pregnant patient. The method includes generating an electrical stimulation current between about 0.01 milliamperes and about 6 milliamperes using a current unit, coupling an electrode probe to the current unit, and inserting the electrode probe transvaginally so that at least one electrode of the electrode probe is in contact with the patient's cervix. The method also includes applying the electrical stimulation current from the current unit through the electrode probe and the at least one electrode to the patient's cervix to produce ripening of the patient's cervix.

Abstract: The present disclosure relates generally to methods, apparatus and systems for beneficial administration of directed energy to target locations on subject. In some implementations, the directed energy is administered at or near the surface of the body and includes one or more forms of energy including but not limited to visible light, infrared light (IR), near infrared light (NIR), electromagnetic fields (EMF, whether pulsed, repetitive, or static), millimeter wave (MW), ultrasound (US) or other therapeutic wavelengths and/or energy forms.

Abstract: A device for transcutaneous electrical stimulation is provided. The device comprises circuitry configured to generate transcutaneous stimulation signals. The device also comprises a first signal output component for electrically connecting to a first electrode connector to deliver generated transcutaneous stimulation signals. The first signal output component comprises a first four-pole electrical connector part. The device further comprises a second signal output component for electrically connecting to a second electrode connector to deliver generated transcutaneous stimulation signals. The second signal output component comprises a second four-pole electrical connector part. The device further comprises a controller to selectively control output of the stimulation signals to selected pairs of poles across the first and second four-pole electrical connector parts.

Abstract: What is provided is an apparatus, system and method for selectively activating one or more target nerves of a mammal by an electric field, including a wireless topical nerve stimulation dermal patch having one or more electrodes configured to provide electric stimulation to one or more target nerves, and a controller configured to receive one or more user inputs and wireless communication from the topical nerve stimulation dermal patch, and configured to send one or more control requests to the topical nerve stimulation dermal patch. The controller configured to determine an activation pattern for the electrodes of the dermal patch to selectively apply the electric field to the target nerve by shaping the electric field in a volume of tissue in proximity of the target nerve by the activation pattern of the electrodes, and the dermal patch configured to activate the electrodes in accordance with the specified activation pattern.

Abstract: Disclosed is an apparatus for providing cranial therapeutic administration of directed energy. The apparatus may include an energy emission device positionable proximate to a surface of the subject's cranium. Further, the apparatus may include multiple energy portals in communication with any of a variety of suitable sources of directed energy. The multiple energy portals are capable of emitting directed energy directed towards the subject's cranium.

Abstract: An exemplary sound processor may include a stimulation management facility that 1) receives an audio signal presented to the patient during a normal operation of the cochlear implant system, and 2) directs a cochlear implant of the cochlear implant system to generate and apply an electrical stimulation pulse representative of the audio signal by way of an electrode included in a plurality of electrodes coupled to the cochlear implant. The sound processor may further include an impedance management facility that determines an impedance of the electrode by directing the cochlear implant to measure a voltage level associated with the electrode while the electrical stimulation pulse is being applied by way of the electrode. Corresponding systems and methods are also described.

Abstract: An exemplary sound processor included in a cochlear implant system associated with a patient may 1) identify a loudness level of an audio signal presented to the patient, 2) determine that a stimulation pulse amplitude corresponding to the loudness level is greater than a maximum stimulation pulse amplitude allowed by a compliance voltage associated with a cochlear implant implanted within the patient, and 3) direct, in response to the determination that the stimulation pulse amplitude is greater than a maximum stimulation pulse amplitude allowed by the compliance voltage, the cochlear implant to represent the loudness level to the patient by directing the cochlear implant to generate and apply one or more stimulation pulses to the patient in accordance with at least one of a first encoding scheme that includes pulse density modulation and a second encoding scheme that includes a combination of pulse amplitude modulation and pulse width modulation.

Abstract: An exemplary system includes 1) an electro-acoustic stimulation (“EAS”) sound processor located external to a patient, 2) a cochlear implant communicatively coupled to the EAS sound processor and implanted within the patient, 3) an electrode array communicatively coupled to the cochlear implant and located within a cochlea of the patient, and 4) a receiver communicatively coupled to the EAS sound processor and configured to be in communication with an ear of the patient. The EAS sound processor operates in accordance with an acoustic-only mode during a post-implant time period and detects audio content presented to the patient, directs the receiver to apply acoustic stimulation, and prevents the cochlear implant from applying electrical stimulation representative of audio content presented to the patient during the post-implant time period. Corresponding systems and methods are also disclosed.

Abstract: A system and method for the evaluation of hearing implant signal processing is described. A cochlear implant signal processor converts a speech signal input into multi-channel stimulation pulse sequences for a cochlear implant electrode array. A temporal feature processing module extracts temporal feature information from the stimulation pulse sequences. A speech recognition engine evaluates the temporal information using automatic speech recognition to produce speech recognition outputs corresponding to the speech signal input.

Abstract: A malleable implantable medical device for implanting in a recipient comprising a flexible region of the medical device, one or more structures proximate to the flexible region, wherein the one or more structures is configured to provide a bending force to the flexible region, and one or more hermetically sealed medical components coupled to the flexible region, wherein the one or more medical components is configured to provide a therapeutic effect on the recipient.

Abstract: A retinal prosthesis system can comprise: a flexible substrate; a nanowire light detector which is placed on the substrate, and comprises one or more nanowires of which the resistance changes according to the applied light; one or more micro-electrodes which are placed on the substrate, are electrically connected to the nanowire light detector, and come in contact with retinal cells; and an electric power supply source for applying electric power to the nanowire light detector and the micro-electrodes. The retinal prosthesis system can be implemented into a very thin and flexible substrate type high resolution retinal system by manufacturing a nanowire light detector on a substrate in which micro-electrodes are implemented.