Patents Issued in September 13, 2016
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Patent number: 9439814Abstract: An absorbent hygiene product for acquiring fluids, having a flexurally yielding topsheet and a flexurally yielding backsheet, has, disposed between these sheets, an absorbent laminate, which in turn has two flexurally yielding outer plies, arranged adheringly between which are at least two diagonally intersecting, pre-tensioned plies of elastic filaments, a quantity of a superabsorbent polymer being incorporated in each of the discrete sections thus formed, and the topsheet-side outer ply of the laminate consists of a hydrophobic material, and the backsheet-side outer ply of the laminate consists of a hydrophilic material.Type: GrantFiled: April 27, 2012Date of Patent: September 13, 2016Assignee: Evonik Degussa GmbHInventor: Wilfried Fenske
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Patent number: 9439815Abstract: Absorbent members and methods of making the same are disclosed. In one embodiment, the absorbent member is a unitary absorbent fibrous web having a density profile through its thickness. In such an embodiment, the density profile of the fibrous web is skewed toward one of the surfaces of the fibrous web. In such embodiments, the maximum density of the web may be located outside of the central 30% zone of thickness of the web.Type: GrantFiled: April 25, 2012Date of Patent: September 13, 2016Assignee: The Procter & Gamble CompanyInventors: Luigi Marinelli, Kirk Wallace Lake, Jill Marlene Orr, Paul Thomas Weisman, Carmine Cimini, Mario Dipilla, Keith Robert Priessman
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Patent number: 9439816Abstract: The present disclosure is directed to disposable absorbent articles comprising a structured fibrous web, the structured fibrous web comprising thermally stable, hydrophilic fibers that are thermally bonded together using heat producing a base substrate that is thermally stable. The base substrate is textured via mechanical treatment to increase its thickness and optionally modified via over bonding to improve its mechanical and fluid handling properties. The structured fibrous web provides optimal fluid wicking and fluid acquisition capabilities and is directed toward fluid management applications.Type: GrantFiled: May 6, 2014Date of Patent: September 13, 2016Assignee: The Procter & Gamble CompanyInventors: Eric Bryan Bond, Carola Elke Beatrice Krippner, John Brian Strube
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Patent number: 9439817Abstract: A water-disintegrable absorbent article adapted to be easily peeled off the wearer's undergarment after use. A pantiliner has a topsheet lying on a body side of the wearer, a backsheet and a liquid-absorbent body interposed between the top- and backsheets. The backsheet may be formed of a water-disintegrable fibrous nonwoven fabric of which the component fibers have an orientation extending in a longitudinal direction. On a non-body side, first adhesive regions adapted to be attached to the wearer's undergarment and second adhesive regions allocated on both outer sides in a transverse direction of the first adhesive regions so as to be spaced in the transverse direction from the first adhesive regions. The first adhesive regions include front first adhesive regions, rear first adhesive regions and central first adhesive regions allocated between the front and rear first adhesive regions spaced apart from each other in the longitudinal direction.Type: GrantFiled: June 7, 2012Date of Patent: September 13, 2016Assignee: Unicharm CorporationInventors: Kiyoko Nishimura, Toshiyuki Tanio, Azusa Matsushima
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Patent number: 9439818Abstract: A fastening tape 100 of a disposable diaper 10 has a base sheet 120 configured by a nonwoven fabric, and a hook sheet 110 in which a plurality of engagement hooks are provided. The KES flexural rigidity value of the entire fastening tape existent region SALL in which the fastening tape 100 is provided, in a longitudinal direction DL of the absorbent main body, is 11.755 gf.cm2 or less.Type: GrantFiled: August 24, 2012Date of Patent: September 13, 2016Assignee: UNICHARM CORPORATIONInventors: Satoru Sakaguchi, Yasuhiro Yamanaka
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Patent number: 9439819Abstract: In a first-aid system including an ultra compact first-aid pouch configured to fit behind the ballistic plates of a protective vest, the first-aid kit is protected from shrapnel and tearing, is easily locatable and removable and does not effect the user's freedom of movement. When the first-aid pouch is removed from its protected location, it presents the first-aid equipment in a logical and easily viewable manner.Type: GrantFiled: January 6, 2015Date of Patent: September 13, 2016Assignee: Phokus Research Group, LLCInventors: Robert J. Hanna, Jonathan M. Gumbert, Daniel C. Stein, Noel Edward Sons
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Patent number: 9439820Abstract: A vehicle having a multiple of level compensation systems is disclosed. The vehicle comprising a chassis having a left frame, a right frame and a base plate, a first level compensation system comprising a pivot joint for pivotably connecting the left and right frames to the base plate around a common rotational axis. A first axial distance from a left rotation axis of a left wheel pair to the rotational axis is different from at least one second axial distance from a right rotation axis of a right wheel pair to the rotational axis, such that the left and right wheel pair have at least one off-set to each other. Moreover a method for traversing stairs with such vehicle is disclosed.Type: GrantFiled: February 25, 2014Date of Patent: September 13, 2016Assignee: Zoomability ABInventors: Karri Zanderléhn, Mikael Löfstrand
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Patent number: 9439821Abstract: A bolster structure system possesses anti-decubitus ulcer characteristics, and may cooperate with a mattress overlay also having anti-decubitus ulcer capabilities as part of a mattress overlay system, in which multiple elongate, positionally adjustable, relatively moveable bolsters are configured for selective placement in conditions of lateral under-engagement with the sides of an overlay to create inclined, lateral side elevations of these sides at locations along the length of the overlay. The bolster structure and overlay may each include a dynamic-response core expanse formed of an open-cell, compressible viscoelastic foam coated with an elastomeric, moisture- and gas-flow-managing, differential-thickness coating structure load-transmissively bonded to the entirety of the outside of said core expanse to function as a dynamically-responsive unit therewith.Type: GrantFiled: July 24, 2015Date of Patent: September 13, 2016Inventor: Michael Dennis
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Patent number: 9439822Abstract: A lifting assembly includes a pillow that may be positioned between a user and a support surface after the user has fallen onto the support surface. The pillow may support a weight ranging between approximately 250 pounds and 500 pounds. A valve is attached to the pillow and a pump is selectively attached to the valve. The pump selectively urges air into the pillow thereby facilitating the pump to inflate the pillow. The pillow lifts the user upwardly from the support surface as the pillow is inflated thereby facilitating the user to stand up. The pillow reaches a height ranging between approximately 18 inches and 25 inches with respect to the support surface when the pillow is inflated.Type: GrantFiled: March 13, 2015Date of Patent: September 13, 2016Inventors: Gloria Davy, Anita Davy
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Patent number: 9439823Abstract: A patient transfer device for transferring a patient resting on a sheet from a first resting device to a second resting device.Type: GrantFiled: February 2, 2015Date of Patent: September 13, 2016Assignee: Nottingham Spirk Design AssociatesInventors: Jason Tilk, William Rabbitt, Rebecca Blice
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Patent number: 9439824Abstract: A device for promoting the extension of the sacrospinal muscles of a person resting on a horizontal surface includes stand having a horizontal cross bar fixed at opposing ends thereof with one each of a front pair legs and a rear pair of legs. Each front leg is pivotally fixed with the cross bar and configurable in both collapsed and extended configurations. At least one rigid post projects away from the cross bar, and at least one elastomeric band, when suspended from the at least one post, is capable of supporting the person around his sacrospinal muscles above the horizontal surface. The front and rear legs rest on the horizontal surface such that the cross bar is elevated above the horizontal surface sufficiently high enough to accommodate the person thereon in a supine position.Type: GrantFiled: February 25, 2015Date of Patent: September 13, 2016Inventor: Michael Alan Shimmel, Sr.
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Patent number: 9439825Abstract: A walker stabilizing platform including a movement restrictor assembly for assisting a user of a walker in transitioning from a sitting position to a standing position wherein the movement restrictor assembly automatically moves from a position of engagement with the walker to a position of disengagement with the walker, and further includes means for allowing the user of the walker to move the movement restrictor assembly from the disengaged position to the engaged position without assistance.Type: GrantFiled: November 11, 2014Date of Patent: September 13, 2016Inventors: Arnold Darryl Bard, Robert Alan Bard
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Patent number: 9439826Abstract: A heel protector (100) includes a leg engaging section (101) and a foot engaging section (102) intersecting at a heel receiver (103). The leg engaging section (101) and the foot engaging section (102) define a leg insertion aperture (104). The leg engaging section (101) defines at least one aperture (203) disposed in an ankle region (205) to permit a connection tube (1002) extending from an inflatable bladder (901) of a compression device (800) to pass therethrough. The heel protector (100) and compression device (800) work together as a rehabilitation system (1300).Type: GrantFiled: February 1, 2013Date of Patent: September 13, 2016Assignee: Medline Industries, Inc.Inventors: Michelle Drey, Margaret Falconio-West, Bruce Shapiro
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Patent number: 9439827Abstract: Tissue compression devices having pressure indicators and methods of using the same. The tissue compression devices provide feedback to a user with respect to the pressure being applied to selected tissue at a selected location such as a radial artery to assist the user in applying the desired amount of pressure to the tissue (such as the pressure needed to achieve hemostasis at an access site). The pressure indication may be provided by a ring indicator that moves between two configurations (e.g., a concave configuration and a convex configuration), a bellow chamber in a housing, a bladder located below a bladder window, etc.Type: GrantFiled: April 25, 2014Date of Patent: September 13, 2016Assignee: Medtronic Vascular, Inc.Inventors: Sanaz Saatchi, Joseph Berglund, Conor Flannery, Mark Hoff, Brian Joseph Mason, Yusuke Miyashita, Remy O'Leary Pieron, Justin Williams
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Patent number: 9439828Abstract: Methods and systems for dynamic compression of venous tissue enable improved blood movement in the extremities. In accordance with an exemplary embodiment, a pressure pad provides a compressive force to the venous plexus region of the foot. The pressure pad is successively withdrawn and re-pressed against the foot. Improved blood circulation may reduce the occurrence of undesirable complications such as deep vein thrombosis, ulcers, and the like.Type: GrantFiled: July 20, 2012Date of Patent: September 13, 2016Assignee: AVEX, L.L.C.Inventors: Matthew Mayer, Peter E. Von Behrens, David M. Mayer, Gerhard Rill
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Patent number: 9439829Abstract: The present invention presents a hypodermic injection apparatus and methods to introduce an agent to a human body in a less painful way by activating inhibitory mechanisms for pain perception. The apparatus comprises a vibration assembly that encircles a needle penetration site, a removable and disposable barrier device that isolates the apparatus from a recipient and from a needle, a mechanical assembly for syringe movement and a power and control electronics housed in a handle assembly. The vibration assembly generates and delivers vibration to the recipient through a resonant vibration chamber that contacts the recipient via the barrier device. A syringe needle penetrates the recipient's tissue through a linear tubular conduit axially located in the vibration chamber. The needle penetration site is encircled by vibration and the needle is enclosed by the barrier device while being retracted from the recipient.Type: GrantFiled: May 12, 2013Date of Patent: September 13, 2016Inventor: Choon Kee Lee
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Patent number: 9439830Abstract: Various embodiments described herein provide a mechanism for transducing transverse vibrational energy into an elastic body of a sexual stimulation device by directly driving the transverse modes of vibration of the elastic body. Additionally, by using an actuator that transduces a force that is proportional to the input current or voltage, the vibration may be driven with any arbitrary waveform.Type: GrantFiled: January 21, 2014Date of Patent: September 13, 2016Inventor: Bryan Joseph Norton
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Patent number: 9439831Abstract: A pedicure bowl has a bottom discharge drain opening communicating with a discharge duct and is arranged to receive a liner to ensure hygienic operation in the form of a thin flexible material applied over the inner surface to contain the liquid within the liner and to cover the drain opening. The drain opening is closed by the liner so that liquid within the container applies downward pressure on the liner at the drain opening and a sealing member is mounted in the duct downstream of the drain opening to prevent air flow so as to form a back pressure underneath the liner to prevent the downward pressure from rupturing the liner. The sealing member is operable to release the back pressure to cause the liner at the discharge opening to rupture.Type: GrantFiled: January 26, 2015Date of Patent: September 13, 2016Inventor: Lan Van Ta
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Patent number: 9439832Abstract: A child-resistant blister package. The package has a top face, a bottom face, and a periphery. The package also has a protection layer with a top face, a bottom face and a periphery; a blister layer with one or more cavities; and an access layer with a top face, a bottom face, and a periphery. The bottom face of the access layer has a line of weakness that allows the unit dose to be removed from the cavity in one-step by applying a force to the top of the cavity and pressing the unit dose through the line of weakness. The bottom face of the protection layer and the top face of the access layer are permanently joined along substantially the entire periphery of the package. The blister package can also contain a tear resistant layer.Type: GrantFiled: October 8, 2013Date of Patent: September 13, 2016Assignee: The Procter & Gamble CompanyInventors: Kurt Franklin Trombley, Karen Lai-Ting Chan, Isabelle Lafosse-Marin, Jay Robert Morosey, Jr., Karla Mishell Sanchez, Kelly Lee Schmeichel
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Patent number: 9439833Abstract: A system includes a cylinder having a bore with a piston disposed therein, the piston moveable along the bore of the cylinder and having a passage therethrough. The system also includes a mixer disposed in the passage in the piston and including at least one porous mixing device, the at least one porous mixing device comprising a three-dimensional lattice defining a plurality of tortuous, interconnecting passages therethrough, and having physical characteristics to sufficiently mix the first and second components, which characteristics include a selected one or more of mean flow pore size, thickness and porosity.Type: GrantFiled: January 31, 2014Date of Patent: September 13, 2016Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventor: Yves A. Delmotte
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Patent number: 9439834Abstract: A medicine distributing system includes a cassette placement portion for temporary placement of an individual distributing cassette including a large number of cells, a medicine container placement portion for temporary placement of a container for medicines, a medicine transporting device configured to put the medicines into the cells, and a distribution control device configured to acquire individual medicine distribution information to control an operation of the medicine transporting device. The medicine distributing system additionally includes a carrier placement portion for temporary placement of a medicine container carrier capable of housing medicine containers in a vertical column, and a medicine container transporting device configured to transport the medicine containers from the carrier placement portion to the medicine container placement portion.Type: GrantFiled: March 9, 2012Date of Patent: September 13, 2016Assignee: TOSHO, INC.Inventors: Yoshihito Omura, Syunji Ohgaya
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Patent number: 9439835Abstract: A system, a device, a method, and a computer program are provided that dispense pharmacy/clinic loaded medications only to a specific patient that has biometric information pre-programmed to a Biometric Electronic Communicating Drug Dispenser (BECDD) device by, e.g., a clinic physician or authorized user. The biometric information may include, e.g., a finger print, a retinal signature, a voice signature, a DNA code, a blood type, or the like.Type: GrantFiled: September 12, 2012Date of Patent: September 13, 2016Assignee: MEDICATION CONTROL SYSTEMS, LLCInventors: Christopher J. DiMartino, Richard Graham
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Patent number: 9439836Abstract: A stimulating pacifier device includes a base, a nipple extending from the base, and a sound generator disposed in the base and configured to transmit sound. The device further includes at least one of a liquid fragrance permeable nipple or a flavored fluid dispenser.Type: GrantFiled: October 28, 2014Date of Patent: September 13, 2016Inventor: Monica H. Thomas
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Patent number: 9439837Abstract: The present invention relates to a photosensitive composition comprising synthetic nanocrystalline hydroxyapatite or a synthetic precursor thereof doped with a rare earth ion, the use of the composition in restorative or cosmetic dentistry, a process for preparing the composition and a method of generating an image of an exposed dentinal surface of a tooth.Type: GrantFiled: October 10, 2011Date of Patent: September 13, 2016Assignees: University of Leeds, The University Court of the University of St. AndrewsInventors: Wilson Sibbett, Christian Thomas Alcuin Brown, Animesh Jha, Steven John Milne, Colin Robinson, Mandeep Singh Duggal, Kyriacos Jack Toumba
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Patent number: 9439838Abstract: The invention relates to a solution to be selectively applied to individual parts of the surface of dental ceramic(s) and a process for using the solution in the dental field. More specifically the invention relates to a solution comprising a) a solvent, b) an effect agent, and c) a complexing agent. The invention also relates to a kit comprising the solution and to a method of using the solution for selectively treating of parts of the surface dental ceramic(s). The invention also relates to a application instrument suitable for applying the solution.Type: GrantFiled: July 27, 2012Date of Patent: September 13, 2016Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Michael Jahns, Philipp Doebert, Holger Hauptmann, Grit Kindler
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Patent number: 9439839Abstract: Provided are a cosmetic solution and a method for producing the cosmetic solution, the cosmetic solution being easy to store and also easy to handle during use, and moreover having a high moisturizing function, without the use of a preservative. Hyaluronic acid/or a hyaluronic acid compound is dispersed in a polyvalent alcohol, also, an organic acid and/or organic acid salt different from the hyaluronic acid and/or hyaluronic acid compound is dispersed in a polyvalent alcohol such that it contains no water. The solution contains 0.01 to 2.0 wt % hyaluronic acid and/or hyaluronic acid compound 97 wt % or more polyvalent alcohol, is weakly acidic; i.e. 5?pH<7 due to the organic acid and/or organic acid salt.Type: GrantFiled: April 17, 2012Date of Patent: September 13, 2016Inventor: Yukako Sugawara
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Patent number: 9439840Abstract: A silicone composite particle composed of a silicone rubber particle and a polyorganosilsesquioxane, wherein the silicone rubber particle has plural dents on its surface and the polyorganosilsesquioxane adheres to the surface of the silicone rubber particle. Also, a method for preparing the silicone composite particle, which includes steps of subjecting organotrialkoxysilane to a hydrolysis and subsequent condensation in the presence of water, an alkaline substance and a silicone rubber particle containing therein a liquid to thereby have a resultant polyorganosilsesquioxane adhered to the surface of the silicone rubber particle, and subsequently removing the liquid.Type: GrantFiled: October 29, 2015Date of Patent: September 13, 2016Assignee: SHIN-ETSU CHEMICAL CO., LTD.Inventor: Yoshinori Inokuchi
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Patent number: 9439841Abstract: Applicants have identified a critical skin benefit package that can be used in liquid alcohol sanitizing compositions that provides lower amounts of skin conditioners in combination with a specific ratio of different emollients that provide improved skin health with chronic repeated use. The package also provides improved skin feel with without a tacky residue upon drying.Type: GrantFiled: June 6, 2013Date of Patent: September 13, 2016Assignee: Ecolab USA Inc.Inventors: Joseph R. Wegner, Cheryl A. Littau
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Patent number: 9439842Abstract: The present invention relates to a use of an acid in a manufacture of an organopolysiloxane through a condensation reaction of a silicon-containing compound containing a silicon-bonded hydroxyl group and a silicon-containing compound containing a silicon-bonded aminoxy group. Particularly, the present invention relates to a low-odor composition including such an organopolysiloxane. The composition according to the present invention can have little odor caused by a by-product produced via the condensation reaction described above.Type: GrantFiled: December 4, 2012Date of Patent: September 13, 2016Assignee: DOW CORNING TORAY CO. LTD.Inventors: Masaru Ozaki, Seiji Hori, Takatoshi Toyama, Kazuhiko Kojima, Tsunehito Sugiura
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Patent number: 9439843Abstract: The invention provides oral care compositions comprising isobutyl magnolol and propylene glycol monolaurate, together with methods of making and using the same. Also described is a method of enhancing the solubility of isobutyl magnolol in an oral care composition comprising effective amount of propylene glycol monolaurate. The composition is for use in the treatment of caries, gingivitis, periodontitis, tooth yellowing and halitosis.Type: GrantFiled: December 2, 2011Date of Patent: September 13, 2016Assignee: Colgate-Palmolive CompanyInventors: Lin Fei, Stanislav Jaracz, Ying Yang, Guofeng Xu
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Patent number: 9439844Abstract: The present invention relates to azomethine-type direct dyes with a tri-aromatic unit having the following formula (I): and their use for coloring keratin fibers, particularly human keratin fibers such as the hair. The invention also relates to a composition for dyeing keratin fibers comprising, in a suitable medium for dyeing, such direct dyes. Another subject of the present invention is a method for dyeing keratin fibers using said dyeing composition. Finally the present invention also relates to precursors for these direct dyes.Type: GrantFiled: December 13, 2012Date of Patent: September 13, 2016Assignee: L'OREALInventors: Stephane Sabelle, Madeline Leduc
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Patent number: 9439845Abstract: The present invention is directed to glycyrrhetinimidyl hydroxyproline alkyl ester compounds and their protected derivatives and cosmetically acceptable salts thereof, methods of making the compounds, cosmetic compositions containing at least one of the compounds and methods of using the same to promote collagen production in human skin. The compounds and cosmetic compositions of the invention provide various advantageous properties to the human skin.Type: GrantFiled: February 28, 2014Date of Patent: September 13, 2016Assignee: REVLON CONSUMER PRODUCTS CORPORATIONInventors: Harry Cai, Dariush Hosseinpour, Alan Meyers
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Patent number: 9439846Abstract: The present invention relates to an oral care composition comprising catechins. We have found that the catechins tend to darken the color of the chalk based toothpaste due to its oxidation which happens at the high pH of the toothpaste. Once the catechins are oxidized and darken the color of the toothpaste it is no longer available as such for providing anti-inflammatory benefits. It is an object of the invention to provide a chalk based toothpaste formulation which does not turn substantially dark due to oxidation of catechins. The present inventors while working with oral care compositions comprising catechins preferably green tea catechins for providing anti-inflammatory benefits, surprisingly found that some selected zinc salts when added in particular quantities do not result in darkening the color of the toothpaste, and also, when stored, are able to deliver green tea catechins.Type: GrantFiled: May 15, 2012Date of Patent: September 13, 2016Assignee: Conopco, Inc.Inventors: Prasun Bandyopadhyay, Gautam Banerjee, Amit Kumar Ghosh, Reshmee Mukhopadhyay, Smitha Ashok Upadhyaya
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Patent number: 9439847Abstract: The present invention relates to a composition for preventing hair loss or enhancing hair growth which comprises a cyclophilin A (CypA) protein, a nucleic acid having a nucleotide sequence encoding the CypA protein, or a CypA protein expression recombinant vector. The composition of the present invention is administered into skin cells to inhibit the IL-1 expression of the skin cells, to modulate the activities of ERK and c-jun, and to increase the expression of NF-kB p65, thereby promoting the growth and development of hair follicles. Therefore, the composition of the present invention can be useful in preventing hair loss or enhancing hair growth.Type: GrantFiled: September 10, 2013Date of Patent: September 13, 2016Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITYInventor: Wonchae Choe
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Patent number: 9439848Abstract: The present invention relates to aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers. Also disclosed are methods for the rheological modification of aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers.Type: GrantFiled: August 27, 2009Date of Patent: September 13, 2016Assignee: BASF SEInventors: Keith Graham, David Normington, Howard R. Dungworth, John M. Plonka
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Patent number: 9439849Abstract: Provided is a composition for preventing or alleviating skin wrinkles containing honeybush (Cyclopia intermedia) extract, a fraction thereof, or a fermented honeybush as an active ingredient. More particularly, the honeybush extract or fermented honeybush of the claimed subject matter can reduce the length and depth of skin wrinkles caused by UV irradiation and reduce the thickness of the epidermal layer, in addition to suppress collagen tissue breakdown reactions, indicating it is excellent in alleviating skin wrinkles, so that it can be effectively used as an active ingredient of a composition for preventing or alleviating skin wrinkles.Type: GrantFiled: July 11, 2012Date of Patent: September 13, 2016Assignee: KOREA INSTITUTE OF ORIENTAL MEDICINEInventors: Sungwook Chae, Hwa-Jung Choi, Jae-Hyoung Song, Goya Choi, Mi Young Lee
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Patent number: 9439850Abstract: The present invention provides a compound which is a polyunsaturated fatty acid (PUFA) derivative of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, for use in treating various skin disorders.Type: GrantFiled: March 11, 2014Date of Patent: September 13, 2016Assignee: Dignity Sciences LimitedInventors: Adam Kelliher, Angus Morrison, Phil Knowles
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Patent number: 9439851Abstract: The present invention provides a novel gastric retention system in the form of a tablet or a capsule coated with an expandable coating, more particularly, with an expandable coating comprising a film-forming polymer and an expandable component.Type: GrantFiled: March 24, 2005Date of Patent: September 13, 2016Assignee: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.Inventors: Nitin Bhalachandra Dharmadhkari, Yashoraj Rupsinh Zala
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Patent number: 9439852Abstract: Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological disorder or pain in a subject that include administering at least one pharmaceutical agent onto a SEM graft in the skull base of the subject. Also provided are methods of treating a neurological disorder or pain in a subject that include forming a SEM graft in the skull base of the subject and administering at least one pharmaceutical agent onto the SEM graft in the skull base of the subject. Also provided are methods of forming a SEM graft in the skull base of a subject, compositions for administration onto a SEM graft in the skull base or into an endonasal reservoir or endonasal reservoir device in a subject, and devices for administering such compositions onto a SEM graft in the skull base of a subject.Type: GrantFiled: June 15, 2015Date of Patent: September 13, 2016Assignee: Massachusetts Eye & Ear InfirmaryInventor: Benjamin S. Bleier
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Patent number: 9439853Abstract: The present invention relates to a new formulation of an enkephalinase inhibitor, such as racecadotril or dexecadotril, the process for the preparation thereof, and the use thereof in the treatment of diarrhea.Type: GrantFiled: December 9, 2011Date of Patent: September 13, 2016Assignee: BIOPROJETInventors: Jean-Stëphane Julien, Marc Maury, Jeanne-Marie Lecomte, Xavier Ligneau, Philippe Robert, Jean-Charles Schwartz
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Patent number: 9439854Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.Type: GrantFiled: July 7, 2015Date of Patent: September 13, 2016Assignee: Helsinn Healthcare SAInventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Alberto Macciocchi, Andrew Miksztal, Thomas Malefyt, Kathleen M Lee
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Patent number: 9439855Abstract: A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia.Type: GrantFiled: November 6, 2014Date of Patent: September 13, 2016Assignee: Vivacelle Bio, Inc.Inventor: Cuthbert O. Simpkins
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Patent number: 9439856Abstract: Disclosed is an effective method of preparing a composition for delivering an anionic drug, the composition comprising an anionic drug as an active ingredient, a cationic lipid, and an amphiphilic block copolymer, wherein the anionic drug forms a complex with the cationic lipid, and the anionic drug/cationic lipid complex is entrapped in a micelle structure formed by the amphiphilic block copolymer.Type: GrantFiled: April 3, 2013Date of Patent: September 13, 2016Assignee: Samyang Biopharmaceuticals CorporationInventors: Muhn-Ho La, Ji-Yeon Son, Sang-Hoon Kim
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Patent number: 9439857Abstract: The present invention relates to foamable compositions for treating acne comprising benzoyl peroxide; to a therapeutic kit comprising such compositions; and to a method of treating acne using such compositions.Type: GrantFiled: December 1, 2008Date of Patent: September 13, 2016Assignee: Foamix Pharmaceuticals Ltd.Inventors: Dov Tamarkin, Doron Friedman, David Schuz, Rita Keynan, Tal Berman, Jorge Danziger
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Patent number: 9439858Abstract: Provided are a liposome including a cationic lipid, a pharmaceutical composition for the delivery of anionic drugs, and a method for delivering anionic drugs to a target site.Type: GrantFiled: April 1, 2014Date of Patent: September 13, 2016Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Hyun-Ryoung Kim, Sang Joon Park, Min Sang Kim
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Patent number: 9439859Abstract: The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof.Type: GrantFiled: November 19, 2013Date of Patent: September 13, 2016Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc., Presidents and Fellows of Harvard CollegeInventors: Frank Alexis, Matteo Iannacone, Jinjun Shi, Pamela Basto, Elliott Ashley Moseman, Ulrich von Andrian, Robert S. Langer, Omid C. Farokhzad, Elena Tonti
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Patent number: 9439860Abstract: Various fenofibrate dosage forms contain a plurality of beads or particles, where the beads or particles include a pharmaceutical composition comprising fenofibrate; from 0.3% to 10% by weight of the beads or particles of a surfactant; and from about 5% to about 15% by weight of the beads or particles of a water soluble or water dispersible cellulosic binder. The mass ratio of the drug to the binder in the dosage form is between about 3.5:1 and 4.5:1; and the dosage form produces a first Cmax in vivo that is between about 10% and about 50% higher than a comparative Cmax produced by a comparative dosage form. The comparative dosage form comprises the drug and the binder in a ratio of between about 5:1 and 15:1.Type: GrantFiled: October 23, 2012Date of Patent: September 13, 2016Assignee: Mylan, Inc.Inventors: Sarat C. Chattaraj, Glenn Allen Redelman, Andrew Alan Shaw
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Patent number: 9439861Abstract: Provided herein, for example, are microspheres comprising a gelatin or gelatin substitute and a copolymer of a N-tris-hydroxymethyl methylacrylamide monomer unit, a diethylaminoethylacrylamide monomer unit and a N,N-methylene-bis-acrylamide monomer unit. Also provided are methods of producing microspheres comprising a gelatin or gelatin substitute and a copolymer of a N-tris-hydroxymethyl methylacrylamide monomer unit, a diethylaminoethylacrylamide monomer unit and a N,N-methylene-bis-acrylamide monomer unit. Further provided herein, for example, are compositions comprising the microspheres and methods of using the microspheres and compositions thereof.Type: GrantFiled: May 8, 2013Date of Patent: September 13, 2016Assignee: Biosphere Medical, SAInventors: Philippe Reb, Marion Pierre, Barbara De Gioannis, James Krom
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Patent number: 9439862Abstract: Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature of the particle compared to particles without the polyvalent cation. The powders are hollow and porous and are preferably administered via inhalation.Type: GrantFiled: April 2, 2014Date of Patent: September 13, 2016Assignee: Novartis AGInventors: Jeffry G Weers, Thomas E Tarara, Luis A Dellamary, Ernest G Schutt
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Patent number: 9439863Abstract: This invention relates to pharmaceutical dosage forms, particularly to pH dependent pharmaceutical dosage forms with enhanced and/or prolonged distribution of a pharmaceutical compound at a target site. More specifically, this invention relates to a controlled release intravaginal pharmaceutical dosage form and, more particularly, to a pharmaceutical dosage form which comprises microspheres encapsulated and/or embedded within a bioerodible polymeric matrix, together the microspheres and the matrix are formed into a caplet and/or tablet.Type: GrantFiled: February 8, 2013Date of Patent: September 13, 2016Assignee: University of the Witwatersrand, JohannesburgInventors: Viness Pillay, Yahya Essop Choonara, Felix Mashingaidse, Pradeep Kumar