Abstract: A method of alternatingly emitting two or more volatile materials comprises the steps of activating a first heater and emitting a first volatile material for a first period of time by emitting the first volatile material at a first primary evaporation rate and emitting the first volatile material at a first secondary evaporation rate after evaporation of the first volatile material at the first primary evaporation rate. The method further includes the steps of deactivating the first heater, activating a second heater, and emitting a second volatile material for a second period of time by emitting the second volatile material at a second primary evaporation rate and emitting the second volatile material at a second secondary evaporation rate after evaporation of the second volatile material at the second primary evaporation rate. The first and second secondary evaporation rates are less than the first and second primary evaporation rates.

Abstract: A device for generating a scented mist of an atomized liquid fragrance oil includes an atomizer complex, a reservoir assembly, a drainage tube, and a vacuum tube. The atomizer complex can atomize the liquid fragrance oil into a scented mist and deliver the scented mist to air outside of the atomizer complex, where the liquid fragrance oil the fragrance oil that is not atomized into the scented mist delivered to the air outside of the atomizer complex includes collected oil that is collected and drained to a reservoir assembly. A drainage tube extends from a bottom area of the atomizer complex into the liquid fragrance oil. The device can filter the liquid fragrance oil in the reservoir assembly and the collected oil from the atomizer complex that drained down the drainage tube. The vacuum tube can suction the filtered liquid fragrance oil and the collected oil into the atomizer complex for atomization.

Abstract: An air freshener removably engages with a structure, such as the supporting post of a rear view mirror of a motor vehicle. The air freshener has a rigidifying core defining a central axis, and an outer portion or sleeve contacting the core that is formed from one or more fragrance loaded polymers. Together, the core and outer portion are shaped to surround a first axis perpendicular to the central axis. The ends of the air freshener are juxtaposed generally opposite one another in closed configuration, and the arm portions of the air freshener flex in directions substantially parallel to the first axis to separate the ends to open the air freshener. A breakable strap and/or connectors may be provided to join the ends together. Alternatively, one end of the air freshener may be inserted within a cavity formed in the opposite end of the air freshener.

Abstract: A sterilization and deodorization apparatus is provided. The sterilization and deodorization apparatus may include a frame that defines an outer appearance of the sterilization and deodorization apparatus, a plasma unit or device disposed on or at one or a first side of the frame, the plasma unit forming a plasma region to generate a plurality of ions, and a filter unit or filter disposed on the other or a second side of the frame which is spaced apart from the frame. The filter unit may include a filter frame having a plurality of through-holes so that air passes therethrough, and a photocatalyst applied to the filter frame to perform photocatalytic reaction.

Abstract: A low dispersion scent sampler for point of sale display has a housing with a front panel to which a label advertising products sold at the point of sale may be affixed. Inside of the housing is a blower connected to a timer control circuit and battery through a pushbutton actuated switch. A scented material is provided in the air flow path from the blower to one or more exhaust ports. When the pushbutton is pressed by a consumer, the blower turns on for a brief period of time to force air over the scented material and then through the exhaust ports for sampling of the scent emitted by the scented material. The on time for the blower is brief to limit exposure to the scent to the space occupied by the consumer.

Abstract: Scent cartridges for use in a networked scent diffusion device include a reservoir that holds a liquid and an atomizer head assembly. An anti-tampering identifier is associated with at least one of the reservoir and the atomizer head assembly. Scent diffusion from the device is based on the condition of the anti-tampering identifier.

Abstract: A method for reducing leakage of bodily fluids or air through lung tissue within a patient is provided. In one embodiment, the method comprises applying, to an appropriate area of lung tissue, an adhesive composition that is derived from a mixture of KH2PO4, metal oxide, a calcium compound, and water, wherein the weight percent ratio of KH2PO4 and the oxide is at least approximately 1:0.5. The method also comprises polymerizing the adhesive composition to form a sealant that substantially seals the body area with a coating.

Abstract: A kit for bonding to biological hard tissues, containing a phosphorylated polysaccharide, a polyvalent metal salt other than phosphates, and a solvent. The adhesive composition for biological hard tissues provided by the kit for bonding to biological hard tissues is suitably used in for medical uses, such as cement for bones or dental cement.

Abstract: The invention relates to a wound dressing which is particularly suitable for therapeutically dressing wounds. Said wound dressing comprises at least one wound covering layer and at least one sorbent based on an activated carbon which has a biocidal and/or biostatic, in particular antimicrobial effect and/or finish.

Abstract: A composition kit for bone healing medical treatment, comprising partially deacetylated chitin (PDC) with a degree of deacetylation in the range of 40-75%. The composition is provided as a kit with a solids fraction and a liquid fraction, provided in separate vials and to be mixed just prior to use. The weight:weight ratio of the solids to liquid fraction is in the range from 1:1.2 to 1:6, and preferably from 1:1.5 to 1:4. The solids fraction comprises the PDC material and calcium phosphate and the liquid fraction comprises water and an acid.

Abstract: The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.

Abstract: The present invention relates to biodegradable scaffolds composed of a naturally-occurring protein backbone cross-linked by a synthetic polymer. Specifically, the present invention provides PEGylated-fibrinogen scaffold and methods of generating and using same for treating disorders requiring tissue regeneration.

Abstract: Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.

Abstract: Many people need vascular access for procedures such as hemodialysis. It is desirable that this access remain open or patent for the entire duration of the course of treatments. A drug delivery device and methods of using the device are introduced that delivery drug to venous anastomosis of a synthetic vascular access shunt. In some embodiments this device serves as the shunt connecting the target artery and vein to create the vascular access shunt.

Abstract: Medical devices for implantation within a body vessel comprising a graft material and a releasable therapeutic agent are provided. The graft material preferably comprises a biocompatible polyurethane and a therapeutic agent. Preferably, the medical device is a stent graft formed by attaching a polyurethane graft material comprising an elutable taxane therapeutic agent to a radially expandable frame.

Abstract: Coatings for medical devices, the coatings including albumin, the methods of forming the coatings, and the coated medical devices are disclosed. In preferred embodiments the medical device is a bioabsorbable stent. The albumin coating layer improves the thromboresistance of the device.

Abstract: The object of the present invention is achieved by providing a copolymer, in particular, a block copolymer which has excellent coating formation ability, adhesive properties to a substrate, and does not adsorb protein; an antithrombotic coating agent which has superior antithrombotic properties and adhesive properties to a substrate to those of the conventional antithrombotic coating agent; and a medical instrument which is obtained by coating the antithrombotic coating agent, and the block copolymer includes a polymer (A) containing a (meth)acrylic ester monomer and a polymer (B) containing a (meth)acrylamide monomer and has excellent coating formation ability and high adhesive properties to a substrate.

Abstract: Reduced-pressure canisters and methods for recycling are disclosed. In one instance, a method for performing multiple reduced pressure treatments on one or more patients includes providing a reduced-pressure treatment system that includes a first canister body, a fluid reservoir, and one or more modules, such as a pump control module. The method involves using the reduced-pressure system and then removing one or more modules and placing the one or more modules in fitted shipping receptacle that disallows shipping of the fluid reservoir. The one or more modules may be reconditioned and coupled to a second canister body. Other systems and methods are disclosed.

Abstract: A fluid level sensor assembly for monitoring a fluid level in a fluid collection canister of a medical waste fluid collection system. The fluid level sensor assembly includes a fluid level sensor configured for monitoring the fluid level in the fluid collection canister and a fluid level sensor cover configured for preventing direct contact between the fluid level sensor and a fluid in the fluid collection canister. The fluid level sensor cover includes a polymeric cap and polymeric sheath extending from the cap. The elongate tubular sheath surrounds an elongate probe of the sensor with the cap positioned at a base of a sensor body of the sensor to prevent direct fluid contact with the elongate sensor probe and the sensor body.

Abstract: An apparatus and method for managing reduced pressure at a tissue site are disclosed. The apparatus comprises a pump for supplying reduced pressure to the tissue site, a motor coupled to the pump to propel the pump, and a drive system electrically coupled to the motor that includes a power source that provides a source of direct current power to the motor during an operational period at a substantially constant current and of sufficient magnitude to supply a targeted reduced pressure during the operational period. The drive system also includes a controller that monitors the pump's loading on the motor by measuring the voltage across the motor to determine whether the motor voltage remains within a predetermined operational range of voltages necessary for maintaining the reduced pressure supplied by the pump proximate to the targeted reduced pressure without directly measuring the reduced pressure using a pressure sensor.

Abstract: The present invention relates to a Heart Assist Device which comprises a motor, a control unit and an internal battery connected to the motor. The control unit is connected to the motor controlling the motor's operation. The motor of the Heart Assist Device further comprises a rotor without an axial pin running in magnetic bearing. The present disclosure has smaller size and consumes less energy to longer battery lives. The device has high power so that it generates high blood flow. The contact surface is small enough so that it does not cause any harmful effects for blood cells and coagulation systems.

Abstract: An intravascular rotary blood pump possesses a catheter (10), a pumping device (50) disposed distally of the catheter and having at its distal end a flexible flow cannula (53) through which blood is either sucked or discharged by the pumping device (50) during operation of the blood pump, and at least one pressure sensor (27, 28A, 30) having at least one optical fiber (28A) which is laid along the flow cannula (53). The optical fiber (28A) and, where applicable, a sliding tube (27) in which the optical fiber (28A) is laid extend along a neutral fiber of the flow cannula (53).

Abstract: A combination of a single-station reverse-osmosis (RO) device comprising a hemodialysis device (HD device) is characterized in that a connection line is provided with a buffer chamber for permeate which serves on the one hand a faster permeate supply into the HD device and on the other hand a generation of a negative transmembrane pressure, and that upon request by the HD device the permeate flows either via the water inlet valve into the HD device or via a flushing valve of the HD device to an outlet.

Abstract: A method of performing peritoneal dialysis is provided. The method involves sensing a pressure in a fluid upstream or downstream of a pump chamber and adjusting a planned peritoneal dialysis treatment based on the sensed pressure to avoid an alarm condition. An intra-peritoneal pressure may be sensed and may be related to a head height of a peritoneal dialysis patient relative to a pump actuation. The fill volume to the peritoneal dialysis patient may also be limited due to the sensed pressure.

Abstract: A fluid-storing, filtering, and gas-discharging apparatus (2) comprising a fluid holder (21), a gas detector (23), and a filter (22). The fluid holder (21) has a protruding apex structure and comprises a fluid inlet and a fluid outlet. A gas-discharging pipe in communication with the outside is arranged on the protruding apex of the fluid holder (21). The gas detector (23) is arranged on the gas-discharging pipe. The filter (22) is fixed within the fluid holder (21) and is connected to the fluid outlet. The fluid-storing, filtering, and gas-discharging apparatus (2) uses the fluid holder (21) and the filter (22) to implement the storage and filtration of a working fluid, while at the same time, the fluid holder (21) having the protruding apex structure ensures complete discharging of gases mixed in the working fluid, thus achieves the goals of fluid storage, filtration, and gas discharge, and provides great reliability.

Abstract: Methods for pathogen reduction in donor blood are performed by exposure of blood to UVC irradiation. Unwanted wavelengths of light, mostly in the infrared spectra, may be precluded from reaching blood by providing a layer of IR-absorbing fluid positioned between blood and the source of UV irradiation, whereby minimizing energy absorption and heating of blood. Some embodiments further disclose utilizing the same IR-absorbing fluid to actively cool blood by flowing the IR-absorbing fluid along the blood flow path.

Abstract: In the removal of white blood cells from blood, the efficiency of white blood cell removal by a filter is improved. Centrifugal force is applied to blood placed in a blood bag by centrifugal separation to form a plurality of separation layers having a concentration gradient of white blood cells. The separation layers are passed through a filter in ascending order of white blood cell concentration to remove the white blood cells from the separation layers. The separation layers from which the white blood cells have been removed are received in a first blood component bag.

Abstract: Systems and methods are disclosed for detecting an interruption of connection between a blood treatment apparatus and a patient blood circulation. The system includes a line shut-off for blocking the venous fluid line arranged between the blood treatment apparatus and a connector, an arterial fluid line arranged between the blood treatment apparatus and the patient blood circulation, a pressure sensor arranged in the venous fluid line or the arterial fluid line for measuring pressure, and a control and evaluation unit for evaluating a pressure curve in time of the pressure measured by the pressure sensor during blocking of the venous fluid line to detect an interruption or disturbance of the connection between the first connection means and the patient blood circulation.

Abstract: A microenvironment of a biological body is controlled, and more particularly, is measured, changed, and monitored with respect to temperature, pH level, moisture and other tissue parameters of a region of the body while, optionally, administering a therapeutic agent to that region.

Abstract: Fluid management system and method of operating a fluid management system which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. The fluid management system may be selectable between pressure control and flow control modes.

Abstract: A device and method for treating a tick bite or other skin wound that may have been exposed to pathogens employs a syringe filled with antipathogen solution whereby the solution is applied under mild pressure directly to the wound site. The device employs spreader/retractor arms to open the wound for better access of the solution into the wound. The method of using the device to cleanse and disinfect a wound is described.

Abstract: Medical apparatus includes a flexible insertion shaft, which is adapted for insertion into a body of a patient. A resilient end section is fixed to the distal end of the insertion shaft and is formed so as to assume, when unconstrained, an arcuate shape. One or more electrodes are disposed at respective locations along the end section. A first lumen runs from the insertion shaft through the end section so as to convey an irrigation fluid to exit the end section through perforations of the electrodes. A second lumen runs through the insertion shaft to a distal opening and is configured to permit a guide wire to pass through the second lumen from the proximal end of the insertion shaft to exit distally through the distal opening, while conveying the irrigation fluid from the proximal end through the distal opening together with the guide wire.

Abstract: The present invention relates to a holder for an injection syringe (18), with a housing (12) designed to receive the syringe, with a stand (14) for placing on a supporting surface, and with retaining means (38, 52, 54, 62, 64) for axially and/or radially fixing the syringe (18) on or in the holder, wherein the retaining means (38, 52, 54, 62, 64) are designed in such a way that an outlet (26) of a syringe (18) arranged vertically in the holder comes to lie facing the free end of the stand (14) and at a distance therefrom.

Abstract: The present application involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety.

Abstract: Disclosed is an implantable device for drug delivery operated by a magnetic force. The device is provided with a body member and an external magnetic controller which is able to move some of the parts in the body member so that the drug inside the body member can be delivered to a site of interest of the animal body without the extra power source.

Abstract: Some embodiments of an infusion pump system may include an occlusion sensor that can be used to detect when an occlusion exists in the fluid path between the medicine reservoir and the infusion site on the user's skin. Such an occlusion may occur, for example, when the fluid flow line (e.g., a cannula, infusion set tubing, or the like) is kinked. If the medicine dispensation path to the user is occluded, the user may receive no dosage or a lower dosage of the medicine. As such, the occlusion sensor can be used to indicate when the fluid is flowing or not flowing, thereby permitting the infusion pump system to communicate an alarm to the user if an occlusion exists.

Abstract: Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed in the controller. The infusion pump is configured to deliver insulin. The glucose sensor senses glucose levels in the subject and provide output signals representative of the glucose levels in the subject. The controller is programmed receives signals from at least one of the glucose sensor and the pump and configured to issue signals to the pump to deliver an amount of insulin determined by a feedback controller that utilizes a model predictive control based on desired glucose levels, insulin amount delivered and measured glucose levels of the subject. The controller is also configured to deliver insulin using a tuning factor (R) for a model predictive controller in the microcontroller as a conservative setting otherwise the system maintains a current tuning factor (R) for the controller.

Abstract: An apparatus comprising a controller. The controller includes an input/output (I/O) module and a rule module. The I/O module is configured to present a question for a patient when communicatively coupled to a user interface and receive patient information in response to the question via the user interface. The rule module is configured to apply a rule to the patient information and generate a suggested insulin pump setting from application of the rule. Other devices, systems, and methods are disclosed.

Abstract: A multi-fluid injector system and methods of operation thereof are presented. One embodiment of such a fluid injector system includes an automatic refill procedure for a fluid injector system comprising a fluid injector and an operably engaged syringe. The procedure includes the step of determining, using an electronic control device operably controlling the fluid injector system, whether a fluid injection procedure involving the syringe is impending. If the electronic control device determines that the fluid injection procedure is not impending, such that the automatic refill will not interfere with the fluid injection procedure, an automatic refill of the syringe is initiated.

Abstract: A dosing method using a device for transferring and dosing biomedical fluids between hospital containers includes a syringe body containing a biomedical fluid and a piston sealed fitted therein, the syringe body including a first extremity having joining elements to a first container and to a second container, and a second extremity opposite the first extremity, the method including gripping a handle having a coupling seat for fastening to the second extremity; placing first temporary fastening elements between the coupling seat and second extremity; placing second temporary fastening elements between the piston and thrust rod; operating a thrust rod of a motorized element mounted in the handle for pushing the piston; and dosing using control elements mounted on the handle, associated with the motorized element to dose volumetric quantities of biomedical fluid from the first container and dispensing to the second container.

Abstract: The invention refers to a shuttering mechanism for controlling translation of a longitudinally moveable component within an elongate housing, the shuttering mechanism comprising at least one set of castellations on the housing and at least one resilient arm associated with the longitudinally moveable component, the resilient arm having a dog resiliently biased towards the castellations so as to engage between or behind the castellations and block the translation, wherein a respective shutter arm is arranged alongside the set of castellations, the shutter arm having a number of consecutive ramped protrusions spaced from each other, wherein the castellations and the ramped protrusions have the same pitch, wherein a profiled surface is formed by the castellations and the ramped protrusions, wherein the shutter arm is moveable in longitudinal direction with respect to the set of castellations, wherein the shutter arm has at least one locking position with its ramped protrusions essentially in phase with the caste

Abstract: The present invention resides in a needleless syringe for injecting an injection objective substance into an injection target area of a living body without using any injection needle; the needleless syringe comprising a main syringe body; an accommodating unit which accommodates the injection objective substance by the aid of a sealing member in an accommodating chamber provided in the main syringe body; a pressurizing unit which pressurizes the injection objective substance accommodated in the accommodating unit to move or destroy the sealing member thereby so that the injection objective substance is discharged to outside; a flow passage unit which forms a discharge port with respect to the injection target area and which defines a flow passage so that the injection objective substance pressurized by the pressurizing unit is discharged via the discharge port to the injection target area; and a preparatory filling unit which fills the flow passage unit with a part of the injection objective substance accommo

Abstract: The body of a portable drug delivery device, especially an injection pen, is provided on its outer surface with a recess, in which directly accessible information is displayed. The information is protected against damages during everyday use by the recessed location.

Abstract: A medication administration device is provided. The device has a flexible tube having an administration end, an activation end and a lumen between the ends. An administration assembly is attached to the administration end. An activation assembly is attached to the activation end. A syringe is disposed within the lumen. The syringe contains the medication and has a first end and an opposite second end. A plunger is disposed within the lumen and operatively connected to the first end of the syringe. A rupturable seal is provided to the second end of the syringe, which end is approximate to the administration end. The activation assembly activates the plunger to break the rupturable seal to establish a fluid communication between the second end of the syringe and the administration assembly. Accordingly, transportation of the medication from the syringe to the medication administration assembly through the medication administration end is allowed.

Abstract: A multi-purpose syringe that may be used both for gravity feeding and syringe pump assisted feeding of a neonate is disclosed. The multi-purpose syringe includes a cap and a plunger. The cap and plunger may be selectively engaged to the barrel depending on whether the neonate is fed by gravity or syringe pump. The cap seals the top of the barrel but allows gas to pass between the inside of the barrel and the environment and traps liquid within the barrel. To this end, the cap has an aperture covered by a hydrophobic member.

Abstract: An apparatus includes a syringe body and a plunger. The syringe body defines a volume configured to contain a medicament. A proximal end portion of the syringe body includes an engagement portion, and a distal end portion of the syringe body includes a delivery tip. A side wall of the syringe body includes a transparent window. The plunger has a distal end portion configured to move within the volume of the syringe body to convey the medicament. An engagement portion of the plunger is configured to interface with the engagement portion of the syringe body to limit rotation of the plunger about a longitudinal axis of the plunger. An outer surface of the plunger includes a series of indicia, at least one which is visible through the transparent window.

Abstract: A needle shield includes a body extending along a longitudinal axis, and having a longitudinal channel configured to receive a syringe. The body has injection and protection positions. A first latching mechanism on the body is radially outwardly deflectable and includes a protuberance extending radially into the channel. A second latching mechanism disposed on the body and proximally of the first latching mechanism is radially outwardly deflectable and includes a tab at a proximal end thereof extending radially into the channel. The tab has a radially inwardly tapering portion toward a proximal edge of the tab oriented generally perpendicularly with respect to the longitudinal axis. In the injection position, an annular ring on the syringe is located distally of the protuberance, and in the protection position, the proximal edge of the tab is in facing engagement with the annular ring to prevent proximal movement of the body on the syringe.

Abstract: The invention refers to an auto-injector for delivering a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow injection needle and a stopper, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position for insertion into the injection site, operating the syringe to inject the dose of medicament, and advancing a needle shroud over the needle for providing needle safety, activating means arranged to lock and release the spring means, wherein the spring means is a single drive spring in the shape of a compression spring grounded distally in the housing and proximally bearing against a thrust collar arranged to transmit load from the spring means via a plunger to the syringe and/or the stopper for needle insertion and injection, wherein the plunger is engageable to the thrust collar for joint axial translation, wherein the plunge

Abstract: A single-use syringe assembly is disclosed which includes a syringe body defining a fluid reservoir and including an engagement surface, a plunger assembly including a plunger rod and a sealing member supported on a distal end of the plunger rod, and a releasable member having a proximal end releasably positioned within a sealing member throughbore and a distal end configured to engage the engagement surface of the syringe body when the sealing member is moved to the advanced position. The proximal end of the releasable member being configured to seal the sealing member throughbore. The releasable member is configured such that a force required to remove the distal end of the releasable member from engagement with the engagement surface of the syringe body is greater than the force required to disengage the proximal end of the releasable member from the sealing member throughbore.

Abstract: Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.