Patents Issued in November 15, 2016
  • CD86 antagonist multi-target binding proteins
    Patent number: 9493564
    Abstract: This disclosure provides a multi-specific fusion protein composed of a CD86 antagonist binding domain and another binding domain that is an IL-10 agonist, an HLA-G agonist, an HGF agonist, an IL-35 agonist, a PD-1 agonist, a BTLA agonist, a LIGHT antagonist, a GITRL antagonist or a CD40 antagonist. The multi-specific fusion protein may also include an intervening domain that separates the other domains. This disclosure also provides polynucleotides encoding the multi-specific fusion proteins, compositions of the fusion proteins, and methods of using the multi-specific fusion proteins and compositions.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: November 15, 2016
    Assignee: APTEVO RESEARCH AND DEVELOPMENT LLC
    Inventors: Peter Armstrong Thompson, Peter Robert Baum, Philip Tan, John W. Blankenship, Sateesh Kumar Natarajan
  • Targeted binding agents against B7-H1
    Patent number: 9493565
    Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: November 15, 2016
    Assignee: MedImmune Limited
    Inventors: Christophe Queva, Michelle Morrow, Scott Hammond, Marat Alimzhanov, John Babcock, Ian Nevin Foltz, Jaspal Singh Kang, Laura Sekirov, Melanie Boyle, Matthieu Chodorge, Ross A. Steward, Kathleen Ann Mulgrew
  • Antibodies to integrin AVB6 and use of same to treat cancer
    Patent number: 9493566
    Abstract: The invention provides antibodies that specifically bind to integrin ?v?6. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting ?v?6.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: November 15, 2016
    Assignee: Seattle Genetics, Inc.
    Inventors: Maureen Ryan, Sussman Django
  • Methods of treating inflammatory and autoimmune diseases with natalizumab
    Patent number: 9493567
    Abstract: Natalizumab is a safe and efficacious treatment for inflammatory and autoimmune diseases, such as multiple sclerosis, Crohn's Disease, and rheumatoid arthritis. Rare occurrences of progressive multifocal leucoencephalopathy during treatment suggest the possibility that it may be related to natalizumab treatment. Monitoring for JCV and informing caregivers and patients about the manifestations of progressive multifocal leucoencephalopathy can improve the safety of natalizumab therapy.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: November 15, 2016
    Assignee: Biogen Inc.
    Inventor: Ivan Lieberburg
  • Anti-EGFR antibodies and antibody drug conjugates
    Patent number: 9493568
    Abstract: The invention relates to anti-epidermal growth factor (EGFR) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: November 15, 2016
    Assignee: AbbVie Inc.
    Inventors: Edward B. Reilly, Andrew C. Phillips, Lorenzo Benatuil, Chung-Ming Hsieh, Jennifer Perez
  • Structural isomers of sc(Fv)2
    Patent number: 9493569
    Abstract: Structural isomers in sc(Fv)2 compositions of anti-human Mpl antibody and humanized anti-human Mpl antibody were separated, and the obtained structural isomers were cleaved at their linkers to confirm that the structural isomers are of single chain diabody type and bivalent scFv type. In addition, the agonistic activities of these structural isomers were revealed to be significantly different. Furthermore, the present inventors discovered that the content ratio of the structural isomers in sc(Fv)2 compositions could be regulated by altering temperature, modifying lengths of the linkers of sc(Fv)2, or amino acids in their variable regions.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: November 15, 2016
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tomoyuki Igawa, Hiroyuki Tsunoda, Akiko Koga, Yasufumi Kikuchi
  • Fixed dosage regimens for anti-type I interferon receptor (IFNAR) antibodies
    Patent number: 9493570
    Abstract: The disclosure provides methods for treating a subject having a type I IFN-mediated disease or disorder comprising administration of a fixed does of an anti-interferon alpha receptor antibody. The disclosure also provides methods for suppressing a type I interferon (IFN) gene signature (GS) in a subject. In addition, the disclosure provides methods of prognosing or monitoring disease progression in a subject having a type I IFN-mediated disease or disorder, methods of predicting a dosage regimen, methods of identifying a candidate therapeutic agent, methods of identifying a patient as a candidate for a therapeutic agent, and methods of designating a personalized therapy.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: November 15, 2016
    Assignee: MedImmune, LLC
    Inventors: Brandon Higgs, Yihong Yao, Bing Wang, Lorin Roskos, Linda Chang
  • Compositions comprising RANK/RANKL antagonists and related compounds for treating pain
    Patent number: 9493571
    Abstract: Disclosed herein are methods of treating pain using comprising RANK/RANKL antagonists.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: November 15, 2016
    Assignee: ANTECIP BIOVENTURES II LLC
    Inventor: Herriot Tabuteau
  • GITR antibodies and methods of inducing or enhancing an immune response
    Patent number: 9493572
    Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: November 15, 2016
    Assignee: GITR, Inc.
    Inventors: L. Mary Smith, Grazyna Szymanska, Paul Ponath, Michael Rosenzweig, Jose F. Ponte
  • Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
    Patent number: 9493573
    Abstract: The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to EGP-1 (TROP-2), CEACAM5, CEACAM6, CD74, CD19, CD20, CD22, CSAp, HLA-DR, AFP or MUC5ac and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 24 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: November 15, 2016
    Assignee: Immunomedics, Inc.
    Inventors: Serengulam V. Govindan, David M. Goldenberg
  • Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
    Patent number: 9493574
    Abstract: The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to EGP-1 (TROP-2), CEACAM5, CEACAM6, CD74, CD19, CD20, CD22, CSAp, HLA-DR, AFP or MUC5ac and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 24 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: November 15, 2016
    Assignee: Immunomedics, Inc.
    Inventors: Serengulam V. Govindan, David M. Goldenberg
  • Methods for manipulating phagocytosis mediated by CD47
    Patent number: 9493575
    Abstract: Methods are provided to manipulate phagocytosis of cancer cells, including e.g. leukemias, solid tumors including carcinomas, etc.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: November 15, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Siddhartha Jaiswal, Irving L. Weissman, Ravindra Majeti, Mark P. Chao
  • Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
    Patent number: 9493576
    Abstract: Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: November 15, 2016
    Assignee: AMGEN INC.
    Inventors: Simon Mark Jackson, Nigel Pelham Clinton Walker, Derek Evan Piper, Bei Shan, Wenyan Shen, Chadwick Terence King, Randal Robert Ketchem, Christopher Mehlin, Teresa Arazas Carabeo
  • Human antigen binding proteins that bind ?-klotho, FGF receptors and complexes thereof
    Patent number: 9493577
    Abstract: The present invention provides compositions and methods relating to or derived from antigen binding proteins activate FGF21-mediated signaling. In embodiments, the antigen binding proteins specifically bind to (i) ?-Klotho; (ii) FGFR1c, FGFR2c, FGFR3c or FGFR4; or (iii) a complex comprising ?-Klotho and one of FGFR1c, FGFR2c, FGFR3c, and FGFR4. In some embodiments the antigen binding proteins induce FGF21-like signaling. In some embodiments, an antigen binding protein is a fully human, humanized, or chimeric antibodies, binding fragments and derivatives of such antibodies, and polypeptides that specifically bind to (i) ?-Klotho; (ii) FGFR1c, FGFR2c, FGFR3c or FGFR4; or (iii) a complex comprising ?-Klotho and one of FGFR1c, FGFR2c, FGFR3c, and FGFR4.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: November 15, 2016
    Inventors: Shaw-Fen Sylvia Hu, Ian Nevin Foltz, Chadwick Terence King, Yang Li, Taruna Arora
  • Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
    Patent number: 9493578
    Abstract: Immunoglobulin compositions that simultaneously co-engage antigens, where one of the antigens is bound bivalently and the other antigen is bound monovalently. The novel immunoglobulins described preferably utilize heterodimeric Fc regions.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: November 15, 2016
    Assignee: Xencor, Inc.
    Inventors: Gregory A. Lazar, Gregory L. Moore
  • Multivalent antibodies and uses therefor
    Patent number: 9493579
    Abstract: The present application describes engineered antibodies, with three or more functional antigen binding sites, and uses, such as therapeutic applications, for such engineered antibodies.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: November 15, 2016
    Assignee: Genentech, Inc.
    Inventors: Kathy L. Miller, Leonard G. Presta
  • Multivalent glycopeptide constructs and uses thereof
    Patent number: 9493580
    Abstract: Glycopeptide conjugates comprising GM2 and/or Gb5 carbohydrate determinants, and methods of making and using such conjugates are disclosed. The immunogenicity of select glycopeptide conjugates is demonstrated.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: November 15, 2016
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Govind Ragupathi, Philip O. Livingston, Jianglong Zhu, David R. Spriggs
  • Process for the manufacture of viscose
    Patent number: 9493581
    Abstract: A process for the manufacture of viscose comprises the steps of: a) providing a non-dissolving pulp as a raw material; b) steeping the pulp in caustic solution; c) processing the steeped pulp; d) steeping the processed steeped pulp for a second time in caustic solution; and e) further processing the pulp from step d) to form a viscose solution.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: November 15, 2016
    Assignee: INNOVIA FILMS LIMITED
    Inventor: Martin Richard Cockroft
  • Alkylated cyclodextrin compositions and processes for preparing and using the same
    Patent number: 9493582
    Abstract: The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degrading agents and chloride.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: November 15, 2016
    Assignee: Cydex Pharmaceuticals, Inc.
    Inventors: Vincent D. Antle, Alvaro Lopes, Daniel Monteiro
  • Anionic polysaccharides functionalized by a hydrophobic acid derivative
    Patent number: 9493583
    Abstract: A novel anionic polysaccharides functionalized by at least one hydrophobic acid derivative. These novel anionic polysaccharides including hydrophobic groups have good biocompatibility and their hydrophobicity can be easily adjusted without detrimentally affecting the biocompatibility or the stability. A method of synthesis which makes it possible to produce them and to pharmaceutical compositions including them.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: November 15, 2016
    Assignee: ADOCIA
    Inventors: Richard Charvet, Remi Soula, Olivier Soula
  • Poly (pentabromobenzyl acrylate) having specific properties
    Patent number: 9493584
    Abstract: Poly (pentabromobenzyl acrylate) having weight average molecular weight (Mw) in the range from 4,000 to 120,000 and polydispersity index of less than 10 as determined by high temperature gel permeation chromatography, wherein the glass transition temperature of the poly (pentabromobenzyl acrylate) is not more than 150 C.°, the poly (pentabromobenzyl acrylate) includes chains which are terminated by an end group derived from a chain length regulator, wherein the end group is a thiol group —SR1, and wherein R1, is a linear or branched alkyl group composed of not less than 8 carbon atom.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: November 15, 2016
    Assignee: BROMINE COMPOUNDS LTD.
    Inventors: Bertha Croitoru, Dov Beruben, Michael Peled, Yaakov Rachmilevitch, Yaniv Hirschsohn, Yelena Epshtein Assor, Ella Rapaport, Dan Kopel
  • Polymeric bead composition comprising polymerized phosphorous-containing acid monomer
    Patent number: 9493585
    Abstract: The present invention is a polymeric bead composition. More particularly the present invention is directed to a new polymeric bead composition formed by suspension polymerization processes from a phosphorous acid containing monomers.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: November 15, 2016
    Assignee: Rohm ad Haas Company
    Inventors: James C. Bohling, Jose Antonio Trejo-O'Reilly
  • Method for producing magnesium alcoholate
    Patent number: 9493586
    Abstract: The purpose of the present invention is to provide a spherical or ellipsoidal magnesium alcoholate having a narrow particle size distribution even when the particle size is small. The present invention provides a method for producing a magnesium alcoholate by adding in a portionwise manner to a reaction system and reacting, metallic magnesium, an alcohol, and at least one of a halogen or a halogen atom-containing compound in the reaction system under alcohol reflux, which is a method for producing a magnesium alcoholate characterized in that a mixture of metallic magnesium, an alcohol, and at least one of a halogen or a halogen atom-containing compound is added to the reaction system at each portionwise addition.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: November 15, 2016
    Assignee: Nippon Soda Co., Ltd.
    Inventor: Hitoshi Kobayashi
  • Metal complexes of salan-type ligands and uses thereof as catalysts for polymerization of alpha-olefins
    Patent number: 9493587
    Abstract: Use of homogeneous catalytic systems which include as a pre-catalyst a complex of a group 4 metal and a Salan ligand in the polymerization of alpha-olefins, is disclosed. The Salan ligand is characterized by a sequential diamino-containing skeleton unit which is non-symmetric, and the pre-catalysts can also be such that are devoid of a symmetry element. The disclosed polymerization results in alpha-olefin polymers such as polypropylene which are characterized by high levels of tacticity. Also disclosed are novel Salan ligands and novel complexes thereof with group 4 metals.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: November 15, 2016
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Moshe Kol, Konstantin Press
  • Diblock copolymer, preparation method thereof, and method of forming nano pattern using the same
    Patent number: 9493588
    Abstract: The present invention relates to a diblock copolymer that may facilitate formation of a finer nano pattern, and be used for manufacture of an electronic device including a nano pattern or a bio sensor, and the like, a method for preparing the same, and a method for forming a nano pattern using the same, The diblock copolymer comprises a hard segment including at least one specific acrylamide-based repeat unit, and a soft segment including at least one (meth)acrylate-based repeat unit.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: November 15, 2016
    Assignee: LG CHEM, LTD.
    Inventors: Yang-Kyoo Han, Je-Gwon Lee, Su-Hwa Kim
  • Polymers with improved ESCR for blow molding applications
    Patent number: 9493589
    Abstract: Disclosed herein are ethylene-based polymers generally characterized by a density greater than 0.954 g/cm3, high load melt index ranging from 10 to 45 g/10 min, a ratio of high load melt index to melt index ranging from 175 to 600, a rheological slope parameter ranging from 0.15 to 0.30, and an ESCR in 10% igepal exceeding 800 hours. These polymers have the beneficial processability and die swell features of chromium-based resins, but with improved stiffness and stress crack resistance, and can be used in blow molding and other end-use applications.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: November 15, 2016
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Jeff F Greco, Qing Yang, Vivek Rohatgi, Mark L. Hlavinka, Jim B Askew
  • Trimodal polyethylene for use in blow moulding
    Patent number: 9493590
    Abstract: A novel polyethylene formed by Ziegler catalyst is devised, for use in blow moulding.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: November 15, 2016
    Assignee: Basell Polyolefine GmbH
    Inventors: Joachim Berthold, Bernd Lothar Marczinke, Diana Dötsch, Rainer Sattel, Iakovos Vittorias, Peter Bisson
  • Ethylene based polymers and articles made therefrom
    Patent number: 9493591
    Abstract: An ethylene-based polymer comprising about 80.0 to 99.0 wt. % of polymer units derived from ethylene and about 1.0 to about 20.0 wt. % of polymer units derived from one or more C3 to C20 ?-olefin comonomers; the ethylene-based polymer having: a CDBI of 60% to 80%; a melt index, I2.16, of about 4.0 to about 12.0 g/10 min.; a high-load melt index, I21.6, of 80.0 to about 160.0 g/10 min.; a melt index ratio (I21.6/I2.16) of 9.0 to 40.0; and a density of from about 0.910 to about 0.930 g/cm3. Articles, such as films, particularly suitable for use in pre-stretch applications, produced from such polymers and methods of making such articles are also provided.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: November 15, 2016
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventor: Alan M. Malakoff
  • Processes for preparing metallocene-based catalyst systems
    Patent number: 9493592
    Abstract: Methods for preparing single and dual metallocene catalyst systems containing an activator-support are disclosed. These methods can include precontacting of the activator-support and an organoaluminum compound, as well as sequential contacting of two different metallocene compounds to form a dual metallocene catalyst system.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: November 15, 2016
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Ted H. Cymbaluk, Max P. McDaniel, Qing Yang, Dennis L. Holtermann, Tony R. Crain
  • Elastic diene terpolymer and preparation method thereof
    Patent number: 9493593
    Abstract: The present invention relates to a long-chain branched elastic terpolymer capable of satisfying excellent processability and elasticity (flexibility) at the same time, which is obtained in the presence of a Group IV transition metal catalyst, and a preparation method thereof. The elastic terpolymer is a copolymer of ethylene, an alpha-olefin having 3 to 20 carbon atoms, and a diene, wherein i) its weight average molecular weight measured by GPC is 100,000 to 500,000, and ii) its LCB Index which is a ratio of 1st harmonics of storage modulus to 5th harmonics of storage modulus measured at 125° C. using a rubber process analyzer according to a LAOS (Large Angles of Oscillation and high Strains) method has a positive value.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: November 15, 2016
    Assignee: LG Chem, Ltd.
    Inventors: Sun Keun Kim, Sung Ho Park, Sung Cheol Yoon, Jun Seok Ko, Soo Young Choi
  • Cationic polymerization process for the synthesis of nano-structured polymers containing graphene
    Patent number: 9493594
    Abstract: A cationic polymerization process for the synthesis of nano-structured polymers containing graphene which comprises reacting graphite oxide dispersed in a solvent by means of ultrasounds, with at least one vinyl monomer and at least one vinyl aromatic monomer, in the presence of at least one strong inorganic acid and suitable for activating a cationic polymerization, wherein: —said graphite oxide contains from 5% to 60% by weight of bound oxygen, —said vinyl monomer contains at least one carboxylic group wherein the ratio between oxygen bound to the oxide and carboxylic groups ranges from 1:10 to 10:1 in moles per mole, and—the ratio between said vinyl aromatic monomer and the sum of the quantity of graphite oxide and vinyl monomer containing carboxylic groups ranges from 50% to 99% by weight.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: November 15, 2016
    Assignee: Versalis S.P.A.
    Inventors: Gino Goffredi, Aldo Longo, Olga Valentino, Riccardo Felisari, Alessandro Casalini
  • Vinylidene fluoride copolymers
    Patent number: 9493595
    Abstract: The invention relates to a copolymer composition of poly(vinylidene fluoride-trifluoropropene) copolymers. The copolymers formed have excellent optical properties, with very low haze, as well as high melting points, excellent flexibility and toughness.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: November 15, 2016
    Assignee: Arkema Inc.
    Inventors: Mehdi Durali, David A. Mountz
  • Vinyl acetate crotonic acid intermediate transfer members
    Patent number: 9493596
    Abstract: An intermediate transfer member that includes a mixture of a polymer, a vinyl acetate crotonic acid copolymer, an optional conductive component, an optional fluoropolymer, and an optional polysiloxane.
    Type: Grant
    Filed: April 12, 2014
    Date of Patent: November 15, 2016
    Assignee: Xerox Corporation
    Inventor: Jin Wu
  • Polymer compound having a specific super strongly acidic sulfo group
    Patent number: 9493597
    Abstract: The present invention provides a polymer compound which comprises both repeating unit “a” represented by the following general formula (1-1) and repeating unit “b” represented by the following general formula (1-2), and has a weight average molecular weight in the range of 1,000 to 500,000, wherein R1 represents a hydrogen atom or a methyl group, R2 represents a single bond, an ester group, or a linear, branched, or cyclic hydrocarbon group having 1 to 12 carbon atoms which may have either or both of an ether group and an ester group, Z represents a phenylene group, a naphthylene group, or an ester group, and “a” and “b” satisfy 0<a<1.0 and 0<b<1.0. There can be provided a polymer compound having a specific super strongly acidic sulfo group, which is soluble in an organic solvent, and suitably used for a fuel cell or a dopant for a conductive material.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: November 15, 2016
    Assignee: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Jun Hatakeyama, Koji Hasegawa, Takayuki Nagasawa
  • Polymers having acid and amide moieties, and uses thereof
    Patent number: 9493598
    Abstract: Polymers are described that are polymerized from at least one reactive vinyl monomer having acid functionality or a salt thereof, and at least one reactive vinyl monomer having amide functionality. These polymers have a molecular weight from about 500 Da to about 15,000 Da; and may additionally comprise one or more solvent adducts. These polymers may be included in compositions that find use in oilfield applications, such as for inhibition and/or prevention of gas hydrates and/or corrosion.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: November 15, 2016
    Assignee: ISP INVESTMENTS LLC
    Inventors: Osama M. Musa, Cuiyue C. Lei
  • Modified polymer
    Patent number: 9493599
    Abstract: The present technology provides a modified polymer which is modified with two or more types of nitrones that include a nitrone having at least one carboxy group and a nitrone having no carboxy group.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: November 15, 2016
    Assignee: The Yokohama Rubber Co., LTD.
    Inventors: Ryota Takahashi, Takahiro Okamatsu
  • Polymer, surface hydrophilizing agent containing said polymer, and manufacturing method for substrate having hydrophilic surface
    Patent number: 9493600
    Abstract: To provide a novel polymer having an excellent non-specific adsorption inhibitory effect, a surface-hydrophilizing agent comprising the polymer, and a method for producing a substrate having a hydrophilic surface. The polymer comprises a hydrophilic repeating unit having a sulfinyl group in a side chain thereof.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: November 15, 2016
    Assignee: JSR CORPORATION
    Inventors: Naoki Hayashi, Toshihiro Ogawa, Shin-ichirou Iwanaga, Kazuhiro Iso
  • Hairy polymeric nanoparticles with first and second shell block polymer arms
    Patent number: 9493601
    Abstract: Compositions and methods are included for preparing a hairy polymeric nanoparticle including first and second shell block polymer arms are at least partially phase-separated and surround a polymeric core. One type of polymeric arm can have a greater polarity than the other type(s) of polymeric arms. A rubber composition including the hairy nanoparticles is also provided.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: November 15, 2016
    Assignee: Bridgestone Corporation
    Inventors: Xiaorong Wang, Hideki Kitano, James Herman Pawlow, Christopher G. Robertson, Yaohong Chen, Yuan-Yong Yan
  • Polyurethaner-based binder for producing cores and casting molds using isocyanates containing a uretonimine and/or carbodiimide group, a mold material mixture containing said binder, and a method using said binder
    Patent number: 9493602
    Abstract: The present invention relates to a polyurethane-based binder using isocyanates containing uretonimine and/or carbodiimide groups for producing cores and casting molds, to a mold material mixture containing the binder, and to a method using the binder for producing casting molds.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: November 15, 2016
    Assignee: ASK CHEMICALS GMBH
    Inventors: Carsten Cornelissen, Diether Koch, Christian Priebe
  • Carbohydrate binders and materials made therewith
    Patent number: 9493603
    Abstract: A binder comprising a polymeric binder comprising the products of a carbohydrate reactant and nucleophile is disclosed. The binder is useful for consolidating loosely assembled matter, such as fibers. Fibrous products comprising fibers in contact with a carbohydrate reactant and a nucleophile are also disclosed. The binder composition may be cured to yield a fibrous product comprising fibers bound by a cross-linked polymer. Further disclosed are methods for binding fibers with the carbohydrate reactant and polyamine based binder.
    Type: Grant
    Filed: May 7, 2011
    Date of Patent: November 15, 2016
    Assignees: Knauf Insulation SPRL, Knauf Insulation, Inc.
    Inventors: Gert R. Mueller, Charles Fitch Appley, Benedicte Pacorel, Carl A. Hampson
  • Compositions containing aromatic isocyanate functional components and aliphatic aromatics isocyanate functional components having improved cure speed
    Patent number: 9493604
    Abstract: A composition comprising in Part 1: a) one or more isocyanate functional components having aromatic isocyanate functional groups; and b) one or more isocyanate functional components having aliphatic isocyanate functional groups; and in Part 2 c) one or more compounds having more than one isocyanate reactive groups: wherein the ratio of aromatic isocyanate functional groups to isocyanate reactive groups is from 0.95 to 1.05 and the ratio of aromatic isocyanate functional groups and aliphatic isocyanate functional groups (total isocyanate groups) to isocyanate reactive groups is from 1.10 to 1.30.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: November 15, 2016
    Assignee: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Ulrich Tribelhorn, Dirk Schwoeppe
  • Epoxy-vinyl copolymerization type liquid resin composition, cured product of the same, electronic/electric apparatus using the cured product, and method of producing the cured product
    Patent number: 9493605
    Abstract: The present invention provides an epoxy-vinyl copolymerization type liquid resin composition and a cured product of the same. The resin composition contains: an epoxy resin having an epoxy resin equivalent of not more than 200 g/eq; an acid anhydride having an unsaturated double bond that is liquid at normal temperature or the acid anhydride having an unsaturated double bond that is liquid at normal temperature and maleic anhydride; a polyfunctional monomer which is liquid at normal temperature; an epoxy resin curing catalyst which accelerates a curing reaction of the epoxy resin with the acid anhydride or with the acid anhydride and maleic anhydride; and a radical polymerization catalyst which accelerates a curing reaction of the polyfunctional monomer.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: November 15, 2016
    Assignee: Hitachi Industrial Equipment Systems Co., Ltd.
    Inventor: Satoru Amou
  • One-step, one-pot process for preparing multiblock and gradient copolymer
    Patent number: 9493606
    Abstract: The present invention relates to the field of tailored di-, tri- and multi-block as well as gradient polyesters/polycarbonates copolymers prepared by introducing monomers simultaneously in the reaction medium in the presence of an organometallic, metal salt or organic catalyst.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: November 15, 2016
    Assignees: Total Research & Technology Feluy, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Marion Helou, Sophie Guillaume, Jean-François Carpentier, Martine Slawinski, William Guerin
  • DMC catalyzed alkoxylation of esters
    Patent number: 9493608
    Abstract: This invention relates to a novel process for preparing an aliphatic hybrid ester/ether polyol. This process simultaneously transesterifies and alkoxylates a mixture of at least one ester group containing compound which is free of ether groups, and at least one or more hydroxyl group containing compound which is free of ester groups; with the proviso that the mixture has an overall hydroxyl number of less than or equal to 350; with at least one alkylene oxide; in the presence of a mixture of catalysts. The catalyst mixture comprises at least one DMC catalyst, and at least one non-alkaline transesterification catalyst.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: November 15, 2016
    Assignee: Covestro LLC
    Inventors: Kenneth G. McDaniel, Rick L. Adkins, Don S. Wardius
  • N-maleimidyl polymer derivatives
    Patent number: 9493609
    Abstract: The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of preparing such linkerless N-maleimidyl polymer derivatives.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: November 15, 2016
    Assignee: Nektar Therapeutics
    Inventor: Xiaoming Shen
  • Low molecular weight polyphenylene ether prepared without solvents
    Patent number: 9493610
    Abstract: Low molecular weight polyphenylene ether (PPE) is made from higher molecular weight PPE without using solvents by extruding the higher molecular weight PPE with a phenolic modifier and a redistribution catalyst. The low molecular weight PPE has a Mw/Mn polydispersity greater than about 2 and a Mn ranging from about 10,000 to about 20,000.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: November 15, 2016
    Assignee: PolyOne Corporation
    Inventor: Roger W. Avakian
  • Polyamide resin composition and molded product
    Patent number: 9493611
    Abstract: A polyamide resin composition includes 100 parts by weight of a (a) polyamide resin; and 0.1 to 10 parts by weight of a (b) hydroxyl group- and carboxyl group-containing compound, wherein the (b) hydroxyl group- and carboxyl group-containing compound has a ratio (COOH/OH) of 0.01 to 5.0 of a rate (percentage) of a carboxyl group-derived peak area to a total peak area in a 13C-NMR spectrum to a rate (percentage) of a hydroxyl group-derived peak area to a total peak area in a 1H-NMR spectrum and has a degree of branching of 0.05 to 0.35.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: November 15, 2016
    Assignee: Toray Industries, Inc.
    Inventors: Atsushi Masunaga, Hiroshi Nakagawa, Hideyuki Umetsu
  • Fiber-reinforced composites made with thermoplastic resin compositions and reactive coupling fibers
    Patent number: 9493612
    Abstract: Methods of making fiber-resin compositions are described. The methods may include the providing of a thermoplastic resin to an extruder, where the thermoplastic resin may include at least one reactive moiety capable of forming a covalent bond with a coupling agent on a plurality of reactive fibers. The methods may further include combining the thermoplastic resin with the plurality of reactive fibers also supplied to the extruder. The reactive fibers are sized with the coupling agent that reacts with the thermoplastic resin to form the fiber-resin composition, which may be extruded from the extruder. Methods of making fiber-reinforced composite articles from the fiber-resin composition are also described.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: November 15, 2016
    Assignee: Johns Manville
    Inventors: Michael J Block, Mingfu Zhang, Asheber Yohannes, Klaus Friedrich Gleich, Jawed Asrar
  • Organic light emitting composition, device and method
    Patent number: 9493613
    Abstract: Disclosed is a crosslinkable light-emitting composition comprising at least one host material, at least one phosphorescent light-emitting dopant, a first crosslinker comprising an unsaturated carbon-carbon bond group and a second crosslinker comprising a ring system capable of undergoing ring-opening crosslinking.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: November 15, 2016
    Assignees: Cambridge Display Technology, Ltd., Sumitomo Chemical Company Limited
    Inventors: Martin Humphries, Richard J. Wilson
  • Polyimide precursor, polyimide, flexible substrate prepared therewith, color filter and production method thereof, and flexible display device
    Patent number: 9493614
    Abstract: The present invention is based on a polyimide precursor having unit structures represented by general formula (1) and unit structures represented by general formula (2), provides a polyimide precursor for which film whitening, cracking and bubbling do not occur regardless of film baking conditions, and provides a flexible TFT array, a flexible color filter, and a flexible substrate with a gas barrier layer using the polyimide precursor, and a flexible display device, etc. using same. (In general formulas (1) and (2), X1-X4 each independently represents a hydrogen atom, C1 to C10 monovalent organic group or C1 to C10 monovalent alkylsilyl group. R1 is represented by general formula (3) and R2 is represented by general formula (4).) (In general formula (4), R3 and R4 each independently represents a C1 to C10 monovalent organic group.
    Type: Grant
    Filed: December 26, 2013
    Date of Patent: November 15, 2016
    Assignee: TORAY INDUSTRIES, INC.
    Inventors: Junji Wakita, Yukari Jo, Masao Tomikawa