Abstract: An arrangement may include a first system provided by a mobile device for processing physiological data representative of a beating heart. The mobile device may be adapted to execute a process for using at least one pattern to detect a notable finding in the physiological data and for sending the notable finding to a second system. The second system may be adapted to execute a process for analyzing the notable finding, for determining at least one new pattern to send to the mobile device, and for sending the at least one new pattern to the mobile device. The at least one new pattern may also include a rule that includes a set of conditions and an action to perform if the set of conditions is met.

Abstract: An organ evaluation device, system, or method is configured to receive electrophysiological data from a patient or model organism and integrates the data in a computational backend environment with anatomical data input from an external source, spanning a plurality of file formats, where the input parameters are combined to visualize and output current density and/or current flow activity having ampere-based units displayed in the spatial context of heart or other organ anatomy.

Abstract: An ambulatory medical device including a plurality of electrodes configured to be disposed at spaced apart positions about a patient's body, an electrode signal acquisition circuit, and a monitoring circuit. The acquisition circuit has a plurality of inputs each electrically coupled to a respective electrode of the plurality of electrodes and is configured to sense a respective signal provided by a plurality of different pairings of the plurality of electrodes. The monitoring circuit is electrically coupled to an output of the acquisition circuit and is configured to analyze the respective signal provided by each of the plurality of different pairings and to instruct the acquisition circuit to select at least one of the plurality of different pairings to monitor based on at least one of the quality of the respective signal, a phase difference between the respective signal and that of other pairings, a position of electrodes relative to the patient's body, and other criteria.

Abstract: An extended wear electrocardiography patch is provided. A flexible backing is formed of an elongated strip of stretchable spunlace material. A layer of stretchable adhesive is applied on at least a portion of a contact surface of the flexible backing, which defines a pair of openings on both ends. A non-stretchable circuit is axially affixed to an outward-facing surface of the flexible backing and has a pair of circuit traces. The flexible backing acts as a buffer between the non-stretchable circuit and the stretchable adhesive and prevents disadhesion of the flexible backing during bending. A pair of electrocardiographic electrodes are electrically coupled to each of the circuit traces. Conductive gel is provided in each of the openings and in electrical contact with the pair of electrocardiographic electrodes as the electrodes shift away from the openings in the flexible backing during the bending.

Abstract: A remotely-interfaceable extended wear electrocardiography and physiological sensor monitor recorder is provided. A sealed housing forms on a bottom surface a cavity shaped to accommodate an upward projection of a battery compartment formed on a non-conductive receptacle of a disposable extended wear electrode patch and includes a set of electrical contacts that protrude from the bottom surface and are arranged in alignment with electrical pads provided on the non-conductive receptacle. Electronic circuitry is provided within the sealed housing and includes an externally-powered micro-controller operable to execute under micro programmable control. An electrocardiographic front end circuit is electrically interfaced to the micro-controller. A wireless transceiver electrically interfaces with the micro-controller and externally-powered flash memory is electrically interfaced with the micro-controller and operable to store samples of the electrocardiographic signals.

Abstract: A method of assessing a brain injury of a patient that comprises performing a brain wave test, performing a pupillary response test, and performing an eye tracking test, then generating a brain injury score based on the results of the brain wave test, the pupillary response test, and the eye tracking test. In some examples, the brain injury score is determined by comparing the test results with a normative database of reference results.

Abstract: Systems and methods for providing quantitative measurements of global glymphatic flow of cerebrospinal fluid (“CSF”) using magnetic resonance imaging (“MRI”) are described. In general, images are obtained from a subject using flow-sensitive MRI techniques that are designed to be particularly sensitive to the glymphatic flow of CSF. Measures of glymphatic flow can be obtained while the subject is in an awake state and again while the subject is in a sleep state. Based on these two measurements, a biomarker that indicates a neurological state or disease can be generated.

Abstract: A positioning cushion for patient undergoing an imaging procedure in a medical imaging apparatus, with a first positioning unit that has a foam material and a second positioning unit, wherein the second positioning unit has at least one fluid cushion able to be filled with a fluid.

Abstract: A location of a number of fiducial points can be computed. The fiducial points can include impedance locations of an electrode disposed on a catheter in an impedance based coordinate system and magnetic locations of a magnetic position sensor disposed on the catheter in a magnetic based coordinate system. The impedance location of the electrode in the impedance based coordinate system can be transformed into a transformed impedance location of the electrode in the magnetic based coordinate system. A magnetic location of the electrode in the magnetic based coordinate system can be determined. A determination of whether an impedance shift exists between the transformed impedance location of the electrode in the magnetic based system and the magnetic location of the electrode in the magnetic based system can be made. An electromagnetic dynamic registration can be generated between the impedance based coordinate system and the magnetic based coordinate system based on the impedance shift.

Abstract: In a method and apparatus for the selection of at least one item of examination information for a medical imaging examination before the medical imaging examination begins, position data of the patient are detected using a position detector. For this purpose, the patient is disposed for the medical imaging examination on a patient support of a medical imaging device. The detected position data are evaluated by a position data evaluation processor, with a patient image that shows a surface image of the patient being created on the basis of the detected position data. The position data evaluation processor determines multiple items of examination information on the basis of the surface image. The multiple items of examination information are presented at an output interface. A selection of at least one item of examination information for the impending medical imaging examination is then made from the multiple displayed items of examination information.

Abstract: A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment. In some embodiments, the system can further include a support surface having one or more sensors incorporated therein either in addition to sensors affixed to the patient or as an alternative thereof. The support surface is, in some embodiments, capable of responding to commands from the host for assisting in implementing a course of action for patient treatment.

Abstract: A posture determination device for determining a user's posture including: a plurality of pressure detection parts disposed in a matrix arrangement on a human body support surface of bedding; a pressure sensing center calculation member to calculate a pressure sensing center of the pressure detection parts based on output values of the pressure detection parts; a determination area setting member to set at least one determination area around the calculated pressure sensing center; and a posture determination member to determine the posture based on distribution condition of the output values of the pressure detection parts within the determination area.

Abstract: A biological information measuring device includes a biological information detecting unit that detects biological information of a user; a motion information detecting unit that detects motion information related to the motion of the user; an informing unit that informs the user of a load state of the user; a condition setting unit that sets informing condition of the load state for the kind of behavior; a behavior analysis unit that analyzes the kind of behavior of the user based on the detected biological information and motion information; a condition determining unit that determines whether the informing condition is satisfied according to the kind of detected behavior of the user which is analyzed based on the detected biological information and motion information; and an informing control unit that informs the informing unit of the load state when it is determined that the informing condition is satisfied.

Abstract: An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.

Abstract: Method and system for providing analyte sensor alignment and retention mechanism for improved connectivity with a transmitter unit for electrical connection, and further including transmitter unit contact pins with metal components to improve electrical conductivity with the analyte sensor in an analyte monitoring and management system is provided.

Abstract: A method and apparatus for non-invasive blood glucose measurement are disclosed. The methods and apparatus utilize exposing a biological object supplied with blood and capable of transmitting infrared radiation therethrough, to an incident beam of polarized infrared radiation with a given angular position of a polarization plane, determining an angular position of a polarization plane of the radiation transmitted through the biological object with a polarizer-analyzer, and measuring an angle shift between said angular positions of the polarization planes of the incident and transmitted radiation, and calculating a glucose concentration C. The methods and apparatus further utilize measuring the length and oscillations of a whisker connected to the polarizer-analyzer and to a rigid support so as to calculate the instantaneous positions of the polarizer-analyzer.

Abstract: A system for withdrawing blood from a body part that avoids formation of a drop of blood on the skin surface of the body part after blood removal. The system includes a collecting unit to withdraw blood, a lancing member configured for insertion into the body part and having a capillary to collect blood, and a pressure piece configured to apply pressure to the body part and having an actuator operably connected thereto. The pressure piece is movable relative to a support configured to exert pressure on the body part, and the actuator is configured to reduce the compressive force of the pressure piece after removing an amount of blood, whereby forming a drop of blood on the skin surface of the body part can be avoided.

Abstract: A biological fluid collection device that allows a blood sample to be collected anaerobically is disclosed.

Abstract: An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.

Abstract: An auditory projective test is provided that emphasizes a shift in focus from visual and verbal/linguistic stimuli to an examination of the phenomena of acoustic and sonic association. The design discovers a “canon” of sound stimuli that may provide psychological associations with the aim to further inform and compliment the findings of Jung's word association test. The design includes a computer software program that gathers and calculates data in Excel format. Jung's traditional Word Association test is presented alongside the sound association test. The design may include the use of digital video recording to help observe and demonstrate behavioral responses. Additionally, the design may include the addition of a digital interface that will reintroduce the measurement of certain physiological data originally used in Jung's association experiments.

Abstract: A diagnostic method and apparatus facilitating a test for diagnosing attention deficit hyperactivity disorder (ADD/ADHD) in a person is disclosed, which in many embodiments includes a visual problem solving test involving distinctive feature analysis. It facilitates making objective observations of multiple components of attention and executive functioning. This test in some embodiments consists of a 24 individual test items with plates of geometric faces. The test requires the subjects to select two identical faces out a field of faces that progressively increase in number and complexity. The geometric faces could instead be graphic faces, stick figures, geometric shapes or other visual stimuli in other embodiments. Correct/incorrect scores and response times are compared to normative data and coupled with structured behavioral observations to provide objective evidence of the subject's attentional and executive functioning status.

Abstract: A feedback device for measuring balance related information, and for producing a stimulation of the skin that encodes that information in a way that is useful to the wearer of the device. At least one sensor detects balance information and transmits at least one balance information signal to a signal processing subsystem. The signal processing subsystem converts the received balance information signal into at least one stimulation control signal. The signal processing subsystem then transmits the stimulation control signal to at least one stimulator, which provides stimulation to a wearer of the device reflecting the stimulation control signal received from the signal processing subsystem.

Abstract: A system may include a mesh that includes a non-electrically conductive mesh material. The system may also include a first electrode coupled to the mesh at a first location of the mesh. The system may further include a second electrode coupled to the mesh at a second location of the mesh that is different from the first location. Additionally, the system may include a control unit electrically coupled to the first electrode and the second electrode. The control unit may be configured to generate a notification signal when the first electrode and the second electrode are electrically coupled to each other.

Abstract: An electronic apparatus includes a processor that generates, on the basis of evaluation of physical strength of a user who is performing physical activity and evaluation of the user's physical condition, information on whether or not the user's physical activity needs to be reconsidered.

Abstract: A system and method for sleep disorder diagnosis and treatment are disclosed.

Abstract: Methods and systems for controlling analyte levels are described. An example method may include receiving a sensor measurement relating to an eye-mountable device. The method also may include determining an analyte concentration based on the one or more sensor measurements, and comparing the analyte concentration to a target analyte concentration. Based on the comparing, the method further may include providing instructions to a drug delivery device, where the instructions are configured to control a drug delivery rate by the drug delivery device.

Abstract: Non-invasive ventilation therapy systems and methods are disclosed. The system comprises a ventilation device, a computing device coupled to the ventilation device, and a plurality of sensors for acquiring a physiological bioelectrical impedance signal from a patient, wherein the sensors are functionally connected to the computing device. The computing device receives the physiological bioelectrical impedance signal from the sensors, analyzes the physiological bioelectrical impedance signal, and, based on the analyzed physiological bioelectrical impedance signal, transmits a signal to the ventilation device to adjust therapy levels.

Abstract: A removable wrist device in a continuous physiological monitoring system includes a mounting fixture with a pair of rails to securely retain another device, such as a battery, a watch, or a display. The rails may be curved to secure the device against displacement during purely translational movement while conveniently conforming to the shape of a wrist. At the same time, the rails can permit movement around the axis of the wrist (where significant rotational forces are not regularly encountered) to permit convenient attachment and removal of the other device to the wrist-mounted device through a rotational, sliding motion. This configuration provides an advantageous combination of ease of use (sliding on and off in a natural motion), mounting tenacity, and comfort.

Abstract: A developers' tool kit including devices and components configured to be inserted or imbedded in an oral cavity or integrated body sensor of an animal or human. The device includes a receptacle for one or more sensors which is further configured to interface a plurality of one or more customizable functions and applications. The functions including, but not limited to, auxiliary body biosensors, data collections, alerting, tracking, reporting, communication network, preset biometric range, preventive-diagnostics to enhance health, and optimize athletic performance. The system includes technology-mining, data-mining, kinematics, integration, multi-media, reporting, and other platforms, analytics and diagnostics to accurately determine health and performance referred to as Oral Sensor Alert and Communication (OSAC).

Abstract: A wearable apparatus for wearing on a head of a user, the apparatus has a band assembly comprising an outer band member comprising outer band ends joined by a curved outer band portion of a curve generally shaped to correspond to the user's forehead; a flexible inner band member comprising inner band ends joined by a curved inner band portion of a curve generally shaped to correspond to the user's forehead, the inner band member is attached to the outer band member at least by each inner band end respectively attached to a respective one of the outer band ends; at least one brainwave sensor disposed inwardly along the curved inner band portion to provide a flexible conductive surface; and a deformable attachment that connects the flexible inner band member to the outer band, the deformable attachment allowing the inner band to conform to the user's forehead shape, the deformable attachment having a biasing component to urge the at the at least one brainwave sensor towards the user's forehead when worn by the

Abstract: A method and system of continuous measuring, monitoring and analyzing sounds from person's body by a wearable wireless sound sensor worn or attached to clothing in close proximity to skin. The method and system include a wearable sensor including a universal attachment of the sound sensor to a user's clothing close or next to their skin in order to perform auscultation and analyze sound signals of the person over any durations of time. A mobile device in communication with the body sound sensor can analyze the collected measured sounds in order to create derived statistics based on received sound during any spans of time including large time intervals.

Abstract: Sensing devices including flexible and stretchable pressure sensors may be associated with or incorporated in garments intended to be worn against a body surface (directly or indirectly), or may be associated with other types of flexible substrates. Systems and methods for storing, communicating, processing, analyzing and displaying data collected by sensor components for remote monitoring of conditions at or near body surfaces are also disclosed. Sensors and sensor systems provide substantially real-time feedback relating to current body conditions and may provide user-specific feedback relating to gait and footwear fit and performance, facilitating improved footwear matching to individual users and improved footwear design and manufacturing, and enabling early intervention when conditions indicate intervention is appropriate.

Abstract: Devices, systems, and, methods for measuring deformation variation in an insole to determine characteristics of a user, including weight and gait, are described herein. In some embodiments, a device includes an insole having a fluid reservoir configured to be disposed in a shoe, a deformation sensor, and a communications module. The fluid reservoir includes a first portion and a second portion. The deformation sensor is coupled to the fluid reservoir and is configured to measure a deformation in at least one of the first portion and the second portion. The communications module is configured to receive the measured deformation from the deformation sensor and transmit the measured deformation to a remote device.

Abstract: The present disclosure provides a remote controller and a health detection system. The remote controller includes a main body, a display module, and a health detection module arranged on the main body. The health detection module is configured to detect a health value of a user, and the health value at least includes a heart rate. The display module is connected to the health detection module and configured to display the health value.

Abstract: The present invention provides an apparatus for reversible stable association with a portable computing and communications device (PCCD) and illuminate the proximity resulting in illumination of an object in the proximity. The present invention provides a compact portable system to facilitate enhanced imaging of an individual employing a portable computing and communications device (PCCD) to participate in a videoconference. The present invention provides an apparatus that retains the PCCD device and provides controlled and customizable illumination of the videoconference participant which results in enhanced imaging of the videoconference participant. The apparatus of the present invention is useful in the practice of telemedicine.

Abstract: An electronic device and method for measuring user body information are provided. The method for measuring user body information includes detecting a contact of a user's body portion on at least two spots of a touch screen of the electronic device, upon detecting the contact of the user's body portion on the at least two spots of the touch screen, applying power to a first coil in the electronic device, and measuring the user body information using at least one of a voltage and a second current measured after a first current is induced across the user's body by a first magnetic field generated from the first coil as the power is applied.

Abstract: An apparatus for measuring biometric information includes a cover, a sensor provided inside the cover, for measuring biometric information, and an electrode assembly provided outside the cover, and having a guide therein in at least partial alignment with a cover opening. The arrangement of the electrode assembly on the outside of the cover provides a measurement distance for measuring the biometric information.

Abstract: A method for monitoring autoregulation includes, using a processor, receiving a blood pressure signal, a regional oxygen saturation signal, and a blood volume signal from a patient. The method also includes determining a first linear correlation between the blood pressure signal and the regional oxygen saturation signal and determining a second linear correlation between the blood pressure signal and the blood volume signal. The method also includes determining a confidence level associated with the first linear correlation based at least in part on the second linear correlation and providing a signal indicative of the patient's autoregulation status to an output device based on the linear correlation and the confidence level.

Abstract: Systems and methods that can distinguish clean from corrupted PPG signals under various types of motions and reconstruct the MNA contaminated data segments, such that biological parameters, e.g., heart rates and SpO2 values, can be accurately estimated, are disclosed.

Abstract: The present invention relates to methods and systems for predicting biomechanical response to wedged insoles. In accordance with one aspect, a method for predicting a biomechanical response to a wedged insole is provided. In a further aspect, a system for predicting a biomechanical response to wedged insole is provided.

Abstract: A method of processing magnetic resonance (MR) lung images creates a quantitative ventilation map of the lung, which is calculated from ventilation images. A step of determining ventilation frequency includes a frequency analysis of a time series of a quantitative lung dimension parameter which is characteristic for the dimension of the lung at the time of collecting the corresponding MR lung image. Creation of the quantitative ventilation map includes selecting a first group of ventilation images, which consists of expiration ventilation images collected at regular expiration phases of multiple ventilation periods, and a second group of ventilation images, which consists of inspiration ventilation images collected at regular inspiration phases of the multiple ventilation periods, and calculating the quantitative ventilation map from the first and second groups of ventilation images, wherein the quantitative ventilation map is adjusted with reference to the tidal volume of the lung.

Abstract: Systems and methods of passive and active alert system for individuals to detect traumatic events using physiological and environmental factors. Exemplary methods include receiving sensor data associated with the individual from a plurality of sensors of a monitoring device and determining whether the sensor data satisfies one or more trigger conditions. For each of the trigger conditions satisfied, one or more messages are sent to at least one of the patient monitoring device and/or an external computing device for analysis. Satisfaction of one or more of the trigger conditions may indicate the individual has been incapacitated and is in need of assistance. The sensor data may have been collected from a heart rate sensor and/or an accelerometer. In some embodiments, the trigger conditions are defined by the individual.

Abstract: Aspects of the present invention relate to analysis of physiological data sequences and activity data recorded while a user participates in various activities. Some aspects relate to alert or messaging system and methods whereby messages are automatically generated when a condition in the physiological or activity data is satisfied. Messages may be automatically formatted with physiological and/or activity data as well as other fields and content. Each message condition may be related to a unique recipient list and message content template.

Abstract: An apparatus for detecting sleep disorders, such as obstructive sleep apnea, includes a housing insertable into an ear canal of a subject. A sensor disposed within the housing measures a position of the subject's head relative to an axis of gravity. A transducer is responsive to the sensor and is capable of creating a stimulus detectable by the subject under certain conditions. In various embodiments, a controller receives signals corresponding to a pitch angle and a roll angle of the subject's head measured by the sensor, determines if the pitch and roll angles correspond to a sleep apnea inducing position, and causes the transducer to generate a stimulus upon determining that the subject's head is in the sleep apnea inducing position more than a predetermined threshold number of times. Various parameters of the stimulus may be modified with successive stimulus generation until a non-sleep apnea inducing position is detected.

Abstract: Provided is a device for detecting stress of a user based on a bio-signal of the user, and when the stress is detected, outputting information of a peripheral device.

Abstract: Disclosed is a detector for a positron imaging unit, comprises a hollow body with an inner cylindrical wall and an outer wall spaced apart from the inner cylindrical wall. The hollow body includes a scintillating material, suitable to emit photons once hit by a 511 keV Y-ray, and one or more pairs of photo-detecting units (e.g. comprising PMTs or SiPM) for detecting photons emitted by the scintillating material; each photo-detecting unit of a pair being placed at opposite ends of the inner cylindrical wall along a radial direction. The scintillating material has scintillation decay time ? lower than 10 ns, an atomic number greater than 10, and a high scintillation yield greater than 8,000 photons/MeV, and comprises a mixture of xenon and argon. An imaging unit including the detector and a method to estimate the differential of the dose of radiation provided in a subject to cancer cells and to surrounding tissues in the course of hadrotherapy is also disclosed.

Abstract: Disclosed herein is a digital mammography device. The digital mammography device comprises a pressure pad configured to be movably installed between an X-ray generator for irradiating X-rays and a detector for receiving X-rays that have passed through an object to be imaged, in such a way as to apply pressure to the object to be imaged; a pressure pad driving part configured to include a motor and a power transferring part for moving the pressure pad by means of the power of the motor, and an applied pressure transferring part configured to include a coupling block to which the pressure pad is fixed to the power transferring part and relatively and movably connected to the coupling block, and provides an electrical signal depending on a relative movement displacement between the coupling block and the mobile block.

Abstract: The invention comprises a method and apparatus for imaging and treating a tumor of a patient using positively charged particles and X-rays. A mounting rail, supporting a scintillation detection system element and an X-ray detection system element, is alternatingly extended/retracted to position the required detection system element opposite a patient tumor position from an exit nozzle of a beam transport system connected to an accelerator of the positively charged particles, where the positively charged particles are alternatingly used to treat the tumor via irradiation. The mounting rail optionally rotates with rotation of the exit nozzle about the patient, such as with rotation of a support gantry.

Abstract: One aspect of the present disclosure relates to a system that can employ multi-modal imaging to provide an image with an enhanced resolution. In some instances, the multi-modal imaging can allow an operator to determine and control a tissue margin without the need for intra-operative tissue pathology. The system can include an imaging system that includes a gamma camera to detect a gamma image and an optical imaging modality to detect an optical image. The system can also include a display device to display an enhanced gamma image created based on a function of the optical image. The enhanced gamma image illustrates a characteristic of a disease in the field of view (e.g., a lymphatic pathway, a sentinel lymph node target, or a satellite disease state).

Abstract: A computer-implemented method for generating an assessment of traumatic brain injury (TBI) includes a TBI assessment computer receiving structural imaging data acquired by performing a structural imaging scan on an individual and generating a structural imaging score based on the structural imaging data. The TBI assessment computer receives functional imaging data acquired by performing a functional imaging scan on the individual and generates a functional imaging score based on the functional imaging data. The TBI assessment computer also receives diffusion imaging data acquired by performing a diffusion imaging scan on the individual and generates a diffusion imaging score based on the diffusion imaging data. Based on the structural imaging score, the functional imaging score, and the diffusion imaging score, the TBI assessment computer generates a TBI assessment score.