Patents Issued in January 12, 2017
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Publication number: 20170008959Abstract: The present invention relates to the identification, functionality and use of domains from the N terminus of the receptor for Advanced Glycation End Products (AGER). These domains, called receptor mulitimerization epitope (RME), are highly conserved in all AGER protein sequences. They represent the mediators for AGER self-association and heteromerization with other proteins. The invention likewise relates to the identification, functionality and use of peptides derived from the C domain of AGER (AGER-CDP). The AGER RMEs and AGER-CDPs of the invention are suitable as target for identifying AGER ligands which modulate the natural ligand interaction; as immunogen for active or passive immunization of individuals, as diagnostic means for identifying immunogenic reactions, and as peptide ligands for modulating protein-protein interactions involving AGER.Type: ApplicationFiled: January 12, 2016Publication date: January 12, 2017Inventors: Alfred Hahn, Ralf Loebbert, Nicole Teusch, Achim Möller, Ulrich Ebert, Martin Schmidt
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Publication number: 20170008960Abstract: Single chain fusion proteins that specifically bind to a TCR complex or a component thereof, such as TCR?, TCR?, or CD3?, along with compositions and methods of use thereof are provided.Type: ApplicationFiled: February 10, 2016Publication date: January 12, 2017Inventors: Valerie Odegard, Catherine J. McMahan, Peter Robert Baum, Peter Armstrong Thompson, Philip Tan, John W. Blankenship, Sateesh Kumar Natarajan
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Publication number: 20170008961Abstract: The invention concerns therapeutic compositions for the treatment of vascularizing cancers, especially, glioblastoma. In particular, the invention is directed to compositions that comprise a molecule having a binding ability that is specific for B7-H3 and a molecule having a binding ability that is specific for a cell-surface factor (or its receptor) that is involved in promoting tumor angiogenesis (especially VEGF or its receptor, VEGFR). The invention is additionally directed to the use of such compositions in the treatment of such cancers, and in particular, in the treatment of glioblastoma.Type: ApplicationFiled: February 11, 2015Publication date: January 12, 2017Inventor: Andrew S. Chi
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Publication number: 20170008962Abstract: The present disclosure provides, in part, compositions comprising peptides immunospecifically binds to defined binding partners, wherein the peptides comprise at least complementarity determining regions relating to the complementarity regions shown in Table 1.Type: ApplicationFiled: July 15, 2016Publication date: January 12, 2017Inventors: Kai W. WUCHERPFENNIG, Bettina FRANZ, Kenneth F. MAY, JR., Glenn DRANOFF, F. Stephen HODI, Christopher HARVEY
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Publication number: 20170008963Abstract: The invention provides compositions and methods for treating diseases associated with expression of EGFRvIII. The invention also relates to chimeric antigen receptor (CAR) specific to EGFRvIII, vectors encoding the same, and recombinant T cells comprising the anti-EGFRvIII CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an anti-EGFRvIII binding domain.Type: ApplicationFiled: June 15, 2016Publication date: January 12, 2017Inventors: Jennifer Brogdon, Laura Alexandra Johnson, Carl H. June, Andreas Loew, Marcela Maus, John Scholler, Hideho Okada
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Publication number: 20170008964Abstract: The present invention relates to anti-FGFR2 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.Type: ApplicationFiled: July 7, 2016Publication date: January 12, 2017Applicant: Novartis AGInventors: David Bryant Batt, Seth Alexander Ettenberg, Nicole Haubst, Tiancen HU, David Jenkins, Matthew John Meyer, Konstantin Petropoulos, Engin Toksoz
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Publication number: 20170008965Abstract: Provided are a wide concentration range, especially high concentration, substantially salt-free anti-prolactin receptor antibody formulations that are substantially isosmotic and of low viscosity.Type: ApplicationFiled: September 27, 2016Publication date: January 12, 2017Inventors: Xinghang MA, Jun XIANG, Jianjie NIU
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Publication number: 20170008966Abstract: The present invention relates to methods of treatment of light chain amyloidosis and other CD38-positive hematological malignancies with anti-CD38 antibodies.Type: ApplicationFiled: May 20, 2016Publication date: January 12, 2017Inventors: Chakra Chaulagain, Raymond Comenzo, Parul Doshi, Xun Ma, Amy Sasser
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Publication number: 20170008967Abstract: Disclosed are antibodies that specifically bind Toll-like Receptor 4 (TLR-4), and to methods of using the anti-TLR4 antibodies as therapeutics and diagnostic agents.Type: ApplicationFiled: September 26, 2016Publication date: January 12, 2017Inventors: Francois Rousseau, Jeremy Loyau, Nicolas Fischer, Greg Elson, Marie Kosco-Vilbois
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Publication number: 20170008968Abstract: Improved methods for treatment of cancer which involve the targeting of slow-growing, relatively mutationally-spared cancer stem line are provided. These methods are an improvement over previous cancer therapeutic methods because they provide for very early cancer treatment and reduce the likelihood of clinical relapse after treatment.Type: ApplicationFiled: February 11, 2016Publication date: January 12, 2017Inventor: Ivan Bergstein
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Publication number: 20170008969Abstract: The present disclosure is directed to antibodies binding to ELTDI. Plexin-B2, Spondin-1, fibulin-1, LINGO I or SLIT3 and methods of using such antibodies to treat and/or diagnose gliomas. Thus, in accordance with the present disclosure, there is provided a method of inhibiting a glioma cell comprising contacting said glioma cell with a first antibody or antibody fragment that binds immunologically to ELTDI, Plexin-B2, Spondin-1 or SLIT3. The method may further comprise contacting said glioma cell with a second anti-cancer agent or treatment.Type: ApplicationFiled: January 6, 2015Publication date: January 12, 2017Applicant: OKLAHOMA MEDICAL RESEARCH FOUNDATIONInventors: Rheal TOWNER, Jonathan WREN
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Publication number: 20170008970Abstract: The present disclosure provides light chain polypeptides that include a C-terminal extension, as well as antibodies and antibody conjugates containing such modified light chain polypeptides, where the C-terminal extension includes one or more cysteine residues. Conjugates that include an antibody of the present disclosure conjugated to an agent via the cysteine residue of the C-terminal amino acid extension are also provided. The present disclosure further provides nucleic acids encoding an antibody light chain polypeptide that includes a C-terminal amino acid extension including a cysteine residue. Pharmaceutical compositions including the antibodies or conjugates of the present disclosure are also provided, as are methods of making and use of the modified anti-bodies and conjugates of the present disclosure.Type: ApplicationFiled: December 23, 2014Publication date: January 12, 2017Inventors: John BABCOOK, James R. RICH, Jan Peter BERGQVIST, Stuart Daniel BARNSCHER
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Publication number: 20170008971Abstract: The invention provides compositions and methods for treating HER2-postitive cancers. The method comprising administering a PD-1 axis binding antagonist and an antibody that targets HER2.Type: ApplicationFiled: June 16, 2016Publication date: January 12, 2017Applicant: Genentech, Inc.Inventors: Mark S. DENNIS, Allen EBENS, Bryan IRVING, Teemu T. JUNTTILA, Ji LI
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Publication number: 20170008972Abstract: We provide an antibody capable of binding to an intracellular PRL-I or PRL-3 polypeptide, in which the antibody is capable of binding to an epitope bound by antibody 269, antibody 223 or antibody 318. Such anti-PRL antibodies may be capable of binding to intracellular PRL-I or PRL-3. They may be suitable for use as therapies against cancer or metastasis thereof, or in clinical diagnosis to identify PRL-3 or PRL-1 positive patients.Type: ApplicationFiled: March 17, 2016Publication date: January 12, 2017Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventor: Qi Zeng
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Publication number: 20170008973Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.Type: ApplicationFiled: March 21, 2016Publication date: January 12, 2017Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry D. Watkins, Cheryl L. Quinn, John D. Mendlein
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Publication number: 20170008974Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.Type: ApplicationFiled: March 21, 2016Publication date: January 12, 2017Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry D. Watkins, Cheryl L. Quinn, John D. Mendlein
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Publication number: 20170008975Abstract: Compositions and methods for treating diseases and disorders expressing tissue inhibitor of metalloproteinase-4 (TIMP-4) are provided.Type: ApplicationFiled: January 28, 2015Publication date: January 12, 2017Inventors: U. Margaretha Wallon, George C. Prendergast
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Publication number: 20170008976Abstract: Expression of proteolytically active, high molecular weight ADAM protease is relatively increased in tumour cells that also express the putative tumour stem cell marker CD133. An antibody or antibody fragment such as 8C7 monoclonal antibody may be used to selectively bind to proteolytically active, high molecular weight ADAM10 protease to thereby detect tumour cells and also as a therapeutic agent for treating cancers, tumours and other malignancies inclusive of leukemia, lymphoma, lung cancer, colon cancer, adenoma, neuroblastoma, brain tumour, renal tumour, prostate cancer, sarcoma and/or melanoma.Type: ApplicationFiled: February 4, 2015Publication date: January 12, 2017Inventors: Martin LACKMANN, Peter W. JANES, Lakmali Atapattu MUDIYANSELAGE, Andrew M. SCOTT, Dimitar B. NIKOLOV, Nayanendu SAHA
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Publication number: 20170008977Abstract: A glycolipopeptide comprising a carbohydrate component, a peptide component and a lipid component, for use as a therapeutic or prophylactic vaccine. Also provided are monoclonal and polyclonal antibodies that recognize the glycolipopeptide of the invention, as well as uses thereof.Type: ApplicationFiled: August 4, 2016Publication date: January 12, 2017Applicant: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.Inventors: Geert-Jan Boons, Therese Buskas, Sampat Ingale, Margaretha Wolfert
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Publication number: 20170008978Abstract: A method may include treating pain, shock, and/or inflammatory conditions in a subject. A method may include using a therapeutically effective amount of an antibody, a lipoxygenase inhibitor, a cytochrome P-450 enzyme inhibitor, and/or an antioxidant configurable to at least partially treat pain, shock, and/or inflammatory conditions in a subject. A method of treating pain, shock, and/or inflammatory conditions in a subject may include inactivating or preventing at least one linoleic acid metabolite to treat certain conditions (e.g., pain, shock, and/or inflammation).Type: ApplicationFiled: September 20, 2016Publication date: January 12, 2017Inventors: Amol Madhusudan Patwardhan, Kenneth Michael Hargreaves, Armen Narakovich Akopian
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Publication number: 20170008979Abstract: Disclosed are a method of preparing a modified conjugated diene-based polymer, a modified conjugated diene-based polymer prepared thereby, and a rubber composition and a tire, including the modified conjugated diene-based polymer. The method of preparing the modified conjugated diene-based polymer includes (a) polymerizing a vinyl aromatic monomer and a conjugated diene monomer using an organo-alkali metal compound in the presence of a hydrocarbon solvent, thus forming an active polymer having an alkali metal end; and (b) coupling or linking the active polymer having the alkali metal end with a compound represented by Chemical Formula 1 or 2.Type: ApplicationFiled: July 20, 2015Publication date: January 12, 2017Applicant: LG Chem, Ltd.Inventors: Moon-Seok Chun, Soo-Yong Lee, Seong-Du Lee
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Publication number: 20170008980Abstract: The present invention generally relates to processes for converting an ester group to an acid group for polymers having a pendant ester of an acid group. This process is generally performed using an aqueous strong base.Type: ApplicationFiled: September 26, 2016Publication date: January 12, 2017Inventors: Eric Connor, Faleh Salaymeh
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Publication number: 20170008981Abstract: The present invention provides a method for producing a chlorinated polyvinyl chloride which is excellent in thermal stability (initial discoloration resistance, heat-resistant stability) and is capable of providing a transparent article. The present invention relates to a method for producing a chlorinated polyvinyl chloride through thermal chlorination of a reaction solution including a vinyl chloride aqueous suspension that contains a vinyl chloride resin in a hermetically sealable reaction vessel, the method including: step 1 of initiating thermal chlorination by heating the reaction solution to 55° C. to 70° C. and then introducing chlorine into the reaction vessel; step 2 of raising the temperature of the reaction solution while maintaining the temperature inside the reaction vessel not higher than the glass transition temperature of a partially chlorinated polyvinyl chloride; and step 3 of carrying out the thermal chlorination at a predetermined temperature of 85° C. or higher but lower than 115° C.Type: ApplicationFiled: March 31, 2015Publication date: January 12, 2017Applicants: SEKISUI CHEMICAL CO., LTD., TOKUYAMA SEKISUI CO., LTD.Inventors: Kenichi MATSUMURA, Norikazu MASHINO
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Publication number: 20170008982Abstract: A polymer comprising recurring units derived from a polymerizable monomer having two structures of hydroxyphenyl methacrylate having a hydroxy group substituted with an acid labile group is used as base resin in a positive resist composition, especially chemically amplified positive resist composition. The resist composition forms a resist film which is processed by lithography into a pattern of good profile having a high resolution, minimal edge roughness, and etch resistance.Type: ApplicationFiled: July 7, 2016Publication date: January 12, 2017Applicant: Shin-Etsu Chemical Co., Ltd.Inventors: Koji Hasegawa, Jun Hatakeyama, Teppei Adachi
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Publication number: 20170008983Abstract: Catalyst systems and methods for making and using the same are described. A method includes selecting a catalyst blend using a blend polydispersity index (bPDI) map. The polydispersity map is generated by generating a number of polymers for at least two catalysts. Each polymer is generated at a different hydrogen to ethylene ratio. At least one catalyst generates a higher molecular weight polymer and another catalyst generates a lower molecular weight polymer. A molecular weight for each polymer is measured. The relationship between the molecular weight of the polymers generated by each of the catalysts and the ratio of hydrogen to ethylene is determined. A family of bPDI curves for polymers that would be made using a number of ratios of a blend of the at least two catalysts for each of a number of ratios of hydrogen to ethylene.Type: ApplicationFiled: February 10, 2015Publication date: January 12, 2017Applicant: Univation Technologies, LLCInventors: Francis C. Rix, Ching-Tai Lue, Timothy M. Boller, Garth R. Giesbrecht, C. Jeff Harlan
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Publication number: 20170008984Abstract: Catalyst systems having both a metallocene catalyst component and a Ziegler-Natta component are disclosed. Such catalyst systems can contain a metallocene compound, an activator-support, an organoaluminum compound, and a Ziegler-Natta component comprising titanium supported on magnesium chloride.Type: ApplicationFiled: June 28, 2016Publication date: January 12, 2017Inventors: Errun Ding, Chung C. Tso, Youlu Yu, Qing Yang, Richard M. Buck
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Publication number: 20170008985Abstract: A polyethylene composition comprising the reaction product of ethylene and optionally one or more alpha-olefin comonomers in the presence of a catalyst composition comprising a multi-metallic procatalyst via solution polymerization; wherein said polyethylene composition is characterized by one or more of the following properties: a melt index, I2, measured according to ASTM D 1238 (2.16 kg @190° C.), of from 0.9 to 5 g/10 min; density (measured according to ASTM D792) from 0.910 to 0.935 g/cc; a melt flow ratio, I10/I2, wherein I10 is measured according to ASTM D1238 (10 kg @ 190° C.), of from 6 to 7.4; and molecular weight distribution (Mw/Mn) of from 2.5 to 3.5 is provided.Type: ApplicationFiled: February 9, 2015Publication date: January 12, 2017Inventors: Mehmet Demirors, Teresa P. Karjala, Carlos G. Alfonzo, Nilesh R. Savargaonkar, Rajen M. Patel, Sylvie Desjardins
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Publication number: 20170008986Abstract: Provided is a tetrafluoroethylene/hexafluoropropylene copolymer which is less likely to form a lump, or is less likely to form a large lump even if a lump is formed, during the formation of an electric wire. The tetrafluoroethylene/hexafluoropropylene copolymer has a melt flow rate measured at 372° C. of 35.0 to 45.0 g/10 minutes and a swell of ?8.0% to 5.0%, the sum of the numbers of —CF2H groups and unstable end groups being 120 or less per 1×106 carbon atoms.Type: ApplicationFiled: January 30, 2015Publication date: January 12, 2017Applicants: DAIKIN INDUSTRIES, LTD., DAIKIN AMERICA, INC.Inventors: Tadaharu ISAKA, Ryouichi FUKAGAWA, Takeshi SHIMONO, Keizou SHIOTSUKI
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Publication number: 20170008987Abstract: A peroxide curable perfluoroelastomer comprising: recurring units derived from tetrafluoroethylene (TFE); recurring units derived from perfluoroethylvinylether (EVE), in an amount of between 2 and 17% by moles, with respect to total recurring units derived from TFE, perfluoromethylvinylether (MVE) and EVE; and recurring units derived from perfluoromethylvinylether (MVE), in an amount of between 23 and 35% by moles, with respect to total recurring units derived from TFE, perfluoromethylvinylether (MVE) and EVE. A process for its manufacture and its use for the manufacture of cured articles.Type: ApplicationFiled: July 14, 2016Publication date: January 12, 2017Inventors: Claudia MANZONI, Milena STANGA, Margherita ALBANO
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Publication number: 20170008988Abstract: There is provided a binder for ceramic formation or a conductive paste, comprising polyvinyl acetal having a degree of acetalization of from 50 to 85 mol %, a content of vinyl ester monomer unit of from 0.1 to 20 mol %, and having a viscosity-average degree of polymerization of from 200 to 5000, wherein a peak-top molecular weight (A) as measured by a differential refractive index detector and a peak-top molecular weight (B) as measured by an absorptiometer (measurement wavelength: 280 nm) in gel permeation chromatographic measurement of the polyvinyl acetal heated at 230° C. for 3 hours satisfy a formula (1) (A?B)/A<0.60 and the polyvinyl acetal has an absorbance in the peak-top molecular weight (B) of from 0.50×10?3 to 1.00×10?2.Type: ApplicationFiled: February 16, 2015Publication date: January 12, 2017Applicant: KURARAY CO., LTD.Inventors: Takeshi KUSUDOU, Yoshiaki ASANUMA, Kazuki TOKUCHI, Yuhi SHIMAZUMI
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Publication number: 20170008989Abstract: A composition results from the mixture of at least one copolymer A resulting from the copolymerisation of at least one monomer functionalised by diol functions and at least one compound A2 comprising at last two boronic ester functions. They have rheological properties which are very varied according to the proportion of the A1 and A2 compounds used. The field is that of associative and exchangeable polymers.Type: ApplicationFiled: January 26, 2015Publication date: January 12, 2017Applicants: TOTAL MARKETING SERVICES, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (ESPCI), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Thi Hang Nga NGUYEN, Renaud NICOLAY, Lise DEVES
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Publication number: 20170008990Abstract: HEMA-compatible siloxane monomers are described that can be used to manufacture contact lenses that combine the attributes of HEMA-based contact lenses with the high oxygen permeability of silicone hydrogel lenses. Optically clear silicone hydrogel contact lens can be manufactured that comprise a polymeric lens body that is the reaction product of a polymerizable composition comprising: a) at least 25 wt. % of at least one hydroxyalkyl methacrylate; and b) at least 20 wt. % of at least one HEMA-compatible polysiloxane.Type: ApplicationFiled: February 25, 2015Publication date: January 12, 2017Applicant: CooperVision International Holding Company, LPInventors: Hiroyuki Ueyama, Charlie Chen, Yuan Xu, Yuwen Liu, Ying Zheng, Paul Richardson, Hong Xue
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Publication number: 20170008991Abstract: Provided are: a graft copolymer which can be safely and stably produced with simple operation, while maintaining the characteristics of an amine, and which is lower in the introduction cost than conventional graft copolymers; and a method for producing the graft copolymer. A polyamine graft polymer that is obtained by polymerizing a polyamine derivative, which is obtained by reacting a polymer compound (a) having at least one amino group with a compound (b) having at least one epoxy group, with an ethylenically unsaturated monomer (c). A method for producing a polyamine graft polymer, which comprises a step for adding, for polymerization, an ethylenically unsaturated monomer (c) and a radical polymerization initiator to a polyamine derivative, which is obtained by reacting a polymer compound (a) having at least one amino group with a compound (b) having at least one epoxy group, in a polar solvent.Type: ApplicationFiled: February 27, 2015Publication date: January 12, 2017Applicant: NITTO BOSEKI CO., LTD.Inventors: Koji WATANABE, Masaru BUNYA
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Publication number: 20170008992Abstract: The present application provides the block copolymers and their application. The block copolymer has an excellent self assembling property and phase separation and various required functions can be freely applied thereto as necessary.Type: ApplicationFiled: December 8, 2014Publication date: January 12, 2017Applicant: LG Chem, Ltd.Inventors: Je Gwon Lee, Jung Keun Kim, No Jin Park, Sung Soo Yoon
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Publication number: 20170008993Abstract: Provided is a block copolymer that makes it possible to produce inorganic nanoparticles that can be dispersed in an organic solvent, the inorganic nanoparticles being of uniform size and a reducing agent not having to be used. A block copolymer including a catechol segment represented by formula (1).Type: ApplicationFiled: February 27, 2015Publication date: January 12, 2017Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCYInventors: Hiroshi YABU, Yuta SAITO
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Publication number: 20170008994Abstract: The present disclosure provides a hybrid benzoxazine resin and a method for producing such a resin by reacting an aldehyde compound and an organic primary monoamine with a multifunctional phenol monomer and a monofunctional phenol monomer in the presence or absence of a solvent. The hybrid benzoxazine resin may be easily recovered and provides a resin that is substantially monofunctional phenol-free and therefore useful in a variety of applications and products, such as in aerospace and transportation interior applications and products.Type: ApplicationFiled: February 10, 2015Publication date: January 12, 2017Inventors: Dong Wang, Derek S Kincaid, Ronald C Smith, Jr., Bradley Rechichar
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Publication number: 20170008995Abstract: The Invention relates to a process for modifying isocyanates, in which at least one monomeric organic isocyanate having an NCO functionality>1 is oligomerized in the presence of at least one spirocyclic ammonium salt having a cation of the formula I as catalysts for the isocyanate modification, where substituents X and Y in the N positions are identical or different, substituted or unsubstituted C2-C20-alkylene chains optionally interrupted by heteroatoms (0, N, S) and by aromatic rings. The invention further relates to the use of such a catalyst.Type: ApplicationFiled: February 13, 2015Publication date: January 12, 2017Inventor: Frank Richter
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Publication number: 20170008996Abstract: The invention relates to a method for modifying isocyanates, wherein at least one organic monomer isocyanate having an NCO functionality >1 is oligomerised in the presence of at least one catalyst, said method being characterised in that the catalyst comprises at least one specific compound having an NPN sequence selected from compounds of formula I (formula I), and/or from compounds of formula II (formula II) where HX represents an acid with a pKa value ?2, X? represents the anion of an acid with a pKa value ?2, and n represents an integer or fractional number between 0 and 20, wherein Y represents R12(R13)N— and/or one or more substituents of the structure of formula III (formula III) and wherein R1 to R19 independently represent identical or different substituents selected from C1-C20 alkyl-, C1-C20 cycloalkyl- and C6-C20 aryl groups, or wherein R1 and R2, R3 and R4, R5 and R6, R7 and R8, R9 and R10, R12 and R13, R14 and R15, R16 and R17, R18 and R19 independently represent identical or different substiType: ApplicationFiled: February 13, 2015Publication date: January 12, 2017Inventor: Frank Richter
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Publication number: 20170008997Abstract: The present invention relates to a polyurethane dispersion comprising particles of a polyurethane dispersed in a dispersing medium, wherein the polyurethane is obtainable by reacting a polyol and an isocyanate, wherein the polyol comprises at least one dimer fatty residue selected from a dimer fatty diacid residue, a dimer fatty diol residue and a dimer fatty diamine residue; and at least one furan dicarboxylic acid residue. The invention also relates to a coating composition comprising the polyurethane dispersion, a polyol for making the polyurethane dispersion, the use of the polyol and a method of making the polyurethane.Type: ApplicationFiled: February 5, 2015Publication date: January 12, 2017Applicant: CRODA INTERNATIONAL PLCInventors: WILHELMUS ADRIANUS JACOBUS HONCOOP, REMCO BENJAMIN VAN TRIET, ANGELA LEONARDA MARIA SMITS
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Publication number: 20170008998Abstract: A shape-memory self-healing polymeric network (SMSHP) is useful as a molded part, a coating, or as a matrix for a composite that can be repaired by heating to a controlled temperature. The SMSHP has thermally reversible repeating units where a thermally reversible adduct is situated between two common linking units formed during a polymerization process between thermally reversible monomers and cross-linking monomers. Optionally, other repeating units can be present from other monomers. Shape-memory results when the SMSHP is warmed to a temperature in excess of its glass transition temperature and self-healing then proceeds when a higher temperature is achieved where thermally reversible adducts dissociates to complementary groups that subsequently reform the adduct without distortion of the memorized shape. The thermally reversible adducts can be Diels-Alder (DA) adducts in a polyurethane, poly urea, or amine epoxy SMSHP network.Type: ApplicationFiled: May 18, 2016Publication date: January 12, 2017Inventors: Henry A. Sodano, Yunseon Heo
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Publication number: 20170008999Abstract: The self-healing cross-linked polymer comprises units of formula (I), wherein: P is a polymeric chain, R1 and R1? are independently selected from the group consisting of: —H, (C1-C20)alkyl, (C5-C14)aryl, —OR4, —(CO)R5, —O(CO)R6, —(SO)R7, —NH—CO—R8, —COOR9, —NR10R11, —NO2, and halogen; R2, R2?, R3 and R3? are independently selected from the group consisting of: —H, (C1-C20)alkyl and (C5-C14)aryl; R4 to R11 are the same or different, and are selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; m is from 3 to 4; n is from 1 to 2; provided that n+m is 5; the polymer having H-bonding interactions and being able to undergo catalyst free aromatic disulfide metathesis at room-temperature, and having a tensile strength value from 0.5 to 1.5 MPa and an elongation at break value higher than 200% at room-temperature.Type: ApplicationFiled: February 28, 2014Publication date: January 12, 2017Inventors: Ibon ODRIOZOLA, Alaitz REKONDO, Roberto MARTIN, Alaitz RUIZ DE LUZURIAGA, Germán CABAÑERO, Hans-jürgen GRANDE
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Publication number: 20170009000Abstract: Fluoropolymer structures are provided for use in aircraft interiors. The structures include an external cross-linked fluoropolymer layer that is lighter and safer than conventional fluoropolymer film layers. In general these structures can be described as a panel for the interior of an aerospace vehicle made of an aluminum or fiber composite facesheet, a foam or honeycomb core attached to the facesheet, and a layer of cross-linked fluoropolymer on the surface of the facesheet that is on the side facing away from the core. Methods of making and using the structures are also provided.Type: ApplicationFiled: February 26, 2015Publication date: January 12, 2017Applicants: DAIKIN AMERICA INC., DAIKIN INDUSTRIES, LTD.Inventors: Ronald E. HENDERSHOT, Kenneth E. MILAM, Katsuhiko IMOTO
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Publication number: 20170009001Abstract: An problem of the present invention is to provide to a (meth)acrylamide-based urethane oligomer which has excellent compatibility with organic solvents, general purpose acrylic monomers and oligomers, and a high curing speed to active energy rays, and to provide an active energy ray curable resin composition which contains the urethane oligomer, has excellent adhesion, moisture resistance and surface curability, and has low curing shrinkage, and a formed product thereof [Means for Solution] By using a (meth)acrylamide-based urethane oligomer of the present invention which has a carbonate skeleton, a diene-based skeleton or a hydrogenated diene-based skeleton in the molecule, one or more (meth)acrylamide groups and a component having a molecular weight of less than 1,000 (excluding a (meth)acrylamide compound (A) having a hydroxyl group) at a content of 5% by weight or less, it is possible to obtain a urethane oligomer which has excellent compatibility with organic solvents, general purpose acrylic monomers anType: ApplicationFiled: March 11, 2015Publication date: January 12, 2017Inventors: Miki TAKENOUCHI, Yusuke ADACHI, Meiri HIRATA
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Publication number: 20170009002Abstract: Disclosed is a polymerizable composition for an optical material containing polyisocyanate (a) including aliphatic polyisocyanate (a1) and a modified aliphatic polyisocyanate (a2); and polythiol (b) having a di- or higher functional thiol group, in which the modified aliphatic polyisocyanate (a2) is contained in the polyisocyanate (a) in the amount of less than or equal to 60 weight %.Type: ApplicationFiled: February 5, 2015Publication date: January 12, 2017Applicant: MITSUI CHEMICALS, INC.Inventors: Hidetaka TSUKADA, Shinsuke ITO, Naoyuki KAKINUMA, Kenichi GOTO, Toshihiko NAKAGAWA, Satoshi YAMASAKI
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Publication number: 20170009003Abstract: Provided is a curable composition that is rapidly cured to form a cured product. The cured product resists yellowing, successfully maintains excellent transparency over a long time even in a high-temperature environment, and is advantageously usable as or in a wafer-level lens. The curable composition according to the present invention includes a cycloaliphatic epoxide (A), a siloxane compound (B), and a curing agent (C). The cycloaliphatic epoxide (A) is represented by Formula (1). The siloxane compound (B) contains two or more glycidyl groups per molecule. In the formula, X is selected from a single bond and a linkage group.Type: ApplicationFiled: February 16, 2015Publication date: January 12, 2017Applicant: DAICEL CORPORATIONInventors: Hiroki TAKENAKA, Kyohei ISHIDA
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Publication number: 20170009004Abstract: This invention relates to a novel curing method of oligomers, using metal triflates, and particularly to the curing of hydroxyl terminated elastomers to achieve crosslinked polymers. The method finds particular use as an alternative cure methodology to replace isocyanate curing. There is further provided a cured and crosslinked polymer binder, which is particularly suitable and compatible for use with energetic materials.Type: ApplicationFiled: April 12, 2016Publication date: January 12, 2017Inventors: Simon Andrew TORRY, Anthony Vernon CUNLIFFE, David Arthur TOD
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Publication number: 20170009005Abstract: A room temperature or low temperature curable epoxy formulation including a) an epoxy component including at least one epoxy resin and b) a hardener component including at least one compound of formula (I) wherein X is a divalent hydrocarbon group, which optionally contains one or more heteroatoms, and n is 0, 1, 2 or 3, preferably 0 or 1, and/or at least one epoxy-amine adduct, which is a reaction product of the compound of formula (I) and an epoxy compound selected from at least one of a monoepoxide and a polyepoxide, as a curing agent. The compounds of formula (I) and the epoxy-amine adduct are suitable as curing agents for epoxy formulations which provide good surface properties and good cure speed, even at low temperature curing. In particular, amine blushing can be avoided or reduced to a large extent, when these curing agents are used.Type: ApplicationFiled: February 24, 2015Publication date: January 12, 2017Applicant: SIKA TECHNOLOGY AGInventors: Claus URBAN, Nina SCHÄFFELER
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Publication number: 20170009006Abstract: Polyarylene oligomers formed from an aromatic dialkyne monomer having a solubility enhancing moiety show improved solubility in certain organic solvents and are useful in forming dielectric material layers in electronics applications.Type: ApplicationFiled: February 29, 2016Publication date: January 12, 2017Inventors: Ping Ding, Peng-Wei Chuang, Christopher Gilmore, Cecilia W. Kiarie, Young-Seok Kim, Jieqian Zhang, Aaron A. Rachford, Shintaro Yamada, James Cameron
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Publication number: 20170009007Abstract: Provided is a versatile heat-curable resin composition for semiconductor encapsulation that has a favorable water resistance and abradability, and exhibits a superior fluidity and a small degree of warpage even when used to perform encapsulation on a large-size wafer. The heat-curable resin composition of the invention contains: (A) a cyanate ester compound having not less than two cyanato groups in one molecule; (B) a phenol curing agent containing a resorcinol-type phenolic resin; (C) a curing accelerator; and (D) a spherical inorganic filler.Type: ApplicationFiled: July 6, 2016Publication date: January 12, 2017Applicant: Shin-Etsu Chemical Co., Ltd.Inventors: Kazuaki SUMITA, Naoyuki KUSHIHARA
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Publication number: 20170009008Abstract: Process and methods for making glycolic acid chemical intermediates and derivatives from biomass are described herein.Type: ApplicationFiled: February 10, 2016Publication date: January 12, 2017Inventors: Johan Van Walsem, Erik Anderson, John Licata, Kevin A. Sparks, Christopher Mirley, Melarkode S. Subramaniya