Abstract: An endoscope reprocessor of the present invention includes a reservoir configured to store a solution, a fluid supply section configured to supply the solution into the reservoir, a fluid discharge section configured to discharge the solution from the reservoir, a recessed pool section fixed inside the reservoir and having a bottom surface positioned below an opening section in a gravitational direction, and a concentration meter including a permeable membrane having a first surface exposed inside the pool section, at least a part of the first surface being positioned below the opening section in the gravitational direction, an accommodation section having a container shape and including a part of a second surface of the permeable membrane as an inner surface, the second surface being on an opposite side to the first surface, internal liquid accommodated in the accommodation section, and an electrode accommodated in the accommodation section.

Abstract: A distal end of an endoscope insertion passage of an overtube is provided with a fluid supply and discharge port. When an observation window of the endoscope insertion part inserted through the endoscope insertion passage is cleaned, an operator can set a distal end surface at a predetermined positioning position using a positioning mechanism, without extracting the endoscope insertion part from the endoscope insertion passage. A concave cleaning storage part that communicates with the fluid supply and discharge port is formed inside the endoscope insertion passage on the distal end side. Cleaning water is supplied from the fluid supply and discharge port to remove foreign matter from the observation window, and stored in the cleaning storage part, and then, the cleaning water stored in the cleaning storage part is suctioned from the fluid supply and discharge port.

Abstract: In a state in which a heat generator and a temperature sensor are disposed on a wiring board, a measurement wiring is disposed in a vicinity of the heat generator, or the temperature sensor is disposed in a vicinity of a heat-generation wiring. A suppressing portion is disposed in either a first heat transfer path extending from the heat generator to the measurement wiring or a second heat transfer path extending from the heat-generation wiring to the temperature sensor. The suppressing portion suppresses heat transfer from the heat generator to the measurement wiring in the first heat transfer path, or suppresses heat transfer from the heat-generation wiring to the temperature sensor in the second heat transfer path.

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: A method of imaging an object includes obtaining an image data set from a raster scan. The image data set has a plurality of data points, each data point having an associated location and intensity; generating a reduced data set by selectively removing one or more data points from the image data set based upon an assigned probability of retaining the one or more data points in the data set, the assigned probability being a function of the intensity of a data point; generating a triangulation graph as a planar subdivision having faces that are triangles, the vertices of which are the data points and the edges of which are adjacent vertices; and segmenting the triangulated data set by finding a path with lowest cost between that vertex and every other vertex, wherein the cost is a function of the respective intensity of the vertices.

Abstract: An image processing apparatus includes a processing unit configured to perform, on a luminance distribution acquired in at least one direction crossing a vessel region in a fundus image of a subject's eye, a first smoothing operation for each first size and a second smoothing operation for each second size smaller than the first size; a first identifying unit configured to identify a position of a vascular wall in the fundus image on the basis of the luminance distribution obtained by performing the first smoothing operation; and a second identifying unit configured to identify positions of inner and outer boundaries of the vascular wall in the fundus image on the basis of the luminance distribution obtained by performing the second smoothing operation.

Abstract: A method for calculating the power of an intraocular lens including measuring an axial separation between the front surface of the cornea and the plane of the iris root; and determining the power of the intraocular lens using the measured axial separation together with other measured parameters and empirically determined lens constants.

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: An apparatus for determining ametropia of an eye includes an optical assembly with a light source, a detector, a plurality of optical elements and at least one stray light stop and a controller. An illumination beam path is provided between the light source and an optical interface in order to allow illumination light generated by the light source to emerge from the optical interface. A measurement beam path is provided between the optical interface and the detector in order to supply measurement light entering through the optical interface to the detector. The measurement beam path passes through an aperture of the at least one stray light stop. A diameter of this aperture is variable or a position of this aperture along the measurement beam path is variable in order to reduce stray light at the detector.

Abstract: Some embodiments are directed to a system and a method for estimating gaze from a set of eye measurement points that are indicative of a gaze pattern of a user viewing a scene. Some other embodiments are directed to obtaining sets of eye measurement points from different users viewing the same scene. In another embodiment, the different sets of eye measurement points are mapped to a common coordinate system for reciprocal calibration. In yet another embodiment, a scene transformation for mapping the common coordinate system to a coordinate system associated with the scene can be calculated by matching eye measurement points from the common coordinate system to interest points of the scene. The scene transformation is thereby calculated more accurately than individually calculated scene transformations, thereby providing a more accurate estimate of the gaze points.

Abstract: A device for monitoring eye movement and pupil response that comprises a first optical pathway for displaying one or more images to the eyes of a patient and a second optical pathway for obtaining images of the eyes of a patient. The device further comprises at least one screen for displaying an image to the left eye of the patient which is not visible to the right eye of the patient and for displaying an image to the right eye of the patient which is not visible to the left eye of the patient; a first camera for capturing images of the left eye of the patient; and a second camera for capturing images of the right eye of the patient at substantially the same time as the first camera is capturing images of the left eye of the patient. The device also comprises at least one IR light source for illuminating the eyes of the patient; and a processor for processing the obtained images and measuring pupil response and/or eye movements.

Abstract: A detection apparatus includes a display, an imaging unit, an eye gaze detector, an output controller, and a gaze point detector. The imaging unit images a subject. The eye gaze detector detects an eye gaze direction of the subject based on a captured image captured by the imaging unit. The output controller displays a diagnostic image that includes an own person image including a face image and a geometric pattern image, onto the display. The gaze point detector detects a first gaze point as a gaze point of the subject in the person image based on the eye gaze direction and detects a second gaze point as a gaze point of the subject in a region that includes at least one of a center of a geometric pattern, a characteristic portion of the geometric pattern, a portion in which density of lines forming the geometric pattern is higher than other portions, and a portion in which the geometric pattern changes, in the geometric pattern image.

Abstract: An optical imaging system (1) for in-vivo retinal imaging, the system (1) comprising: an optical source (3) for generating incoherent light in a plurality of wavelength bands; an optical imaging sub-system (6) configured to split light from said optical source (3) into a plurality of beams, to introduce a path difference between said beams of light, and recombine those beams to form interference fringes that are imaged on a subject (21); and an image capture device (29) configured to capture light from the subject (21) being imaged, and to form an image of said subject (21).

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: The present invention relates to an adaptor for a slit lamp microscope. According to one embodiment of the present invention, the invention provides the advantages of: facilitating the maintenance/repair of a slit lamp microscope since a camera member used for the slit lamp microscope is simply attached or detached; simply and easily inspecting and photographing a subject's eye; and obtaining a high-resolution video or image for the subject's eye at low costs.

Abstract: An apparatus for analyzing a biosignal is provided. The apparatus includes a communicator configured to receive from an external device a first biosignal of an object detected by the external device; a synchronizer configured to transmit a synchronization signal to from the external device or receive the synchronization signal from the external device; at least one biosignal detector configured to detect a second biosignal of the object according to the synchronization signal; and a processor configured to compare characteristics of the first biosignal and the second biosignal and obtain biometric information having correlation with a result of the comparison.

Abstract: The present invention provides a portable holdable device, system and method for conducting a remote primary medical examination, the device comprising: at least one input means for collecting self generated measurements of at least one health characteristic of a patient; a wireless network connection for receiving and transferring at least one signal from the input means to a physician thereby, transferring physiological data of the patient. The wireless network connection communicates with a user interface platform (UIP); the UIP comprises a predetermined protocol comprising a plurality of medical characteristics and conditions selectable according to patient's current physical condition. The self generated measurements of the patient are collectable, storable and deliverable by said input means on demand by said physician.

Abstract: A diagnostic result is immediately presented using a diagnostic apparatus installed in a diagnostic apparatus installation facility. Provided is a diagnostic service system which includes a diagnostic apparatus installed in a diagnostic apparatus installation facility and performing a diagnosis using a disposable device, a user terminal owned by a user of the diagnostic apparatus, and an information processing apparatus connected with the diagnostic apparatus and the user terminal and gathering a diagnostic result of the diagnostic apparatus, in which the information processing apparatus manages information of the diagnostic result diagnosed by the diagnostic apparatus and information of the user by associating the both with each other, and provides the diagnostic result in accordance with an access from the user terminal of the user.

Abstract: An output device includes a processor, wherein the processor executes a process. The process includes acquiring information including user identification information, device identification information for identifying a measuring device, a measurement value of each measurement type obtained by the measuring device, and measurement time of the measurement value, from different measuring devices. The process includes identifying information including measurement values associated with the same user identification information and the same measurement type, from the acquired information. The process includes determining whether time-series variation in the measurement values included in the identified information is different between a first measuring device and a second measuring device identified by the device identification information included in the identified information.

Abstract: An external medical device including monitoring circuitry and communication circuitry. The monitoring circuity monitors a cardiac condition of a patient using the external medical device. For example, the communication circuitry initiates a communication link with a remote location. The remote location can be selected based on data associated with at least one of the external medical device and the patient using the external medical device. In some examples, supporting data can be transmitted to the remote location.

Abstract: The present invention relates to an optical sensor that is formed in an integrated circuit based on CMOS technology and that comprises: one or more photocells including one or more photodetector active areas and an optical stack formed on the photodetector active area(s); and light shielding means, that are formed in or on the optical stack, and are configured, for each photocell, to define an angular range around a given incident direction with respect to said photocell, block incident light with incidence angle outside the defined angular range, and allow incident light with incidence angle within the defined angular range to propagate through the optical stack down to a respective photodetector active area; whereby the light shielding means limit angular response of the optical sensor.

Abstract: At least one processor is configured to control transmission of infrared rays from an infrared transmitter. A signal reception unit is configured to receive waveform signals of the infrared rays received by an infrared receiver. The at least one processor is configured to measure pulses of a user who wears an earphone based on the waveform signals and to control a transmission pattern of the infrared rays from the infrared transmitter based on which of accuracy in measurement of pulses and power saving is prioritized.

Abstract: One aspect of the invention provides a method for assessing peripheral arterial function in a subject. The method includes: conducting diffuse correlation spectroscopy on a local region of the subject; applying pressure to restrict blood flow to the local region for a period of time; conducting diffuse correlation spectroscopy on the local region while the pressure is applied; releasing the pressure; and conducting diffuse correlation spectroscopy on the local region after the pressure is released. Another aspect of the invention provides a system including: a diffuse correlation spectroscopy device and a pressure cuff.

Abstract: A three-dimensional electronic patch includes a flat flexible circuit substrate that includes an elastic layer including a first portion and a second portion. The second portion includes at least side connected to the elastic layer and one or more sides defined by one or more cuts in the elastic layer. The three-dimensional electronic patch further includes a first sensor on the first portion of the elastic layer, a first conductive sensing pad under the first portion of the elastic layer and in electrical connection with the first sensor, and a conductive layer under the second portion of the elastic layer and in electrical connection with the first sensor. The second portion is folded to position the conductive layer away from the first portion.

Abstract: Automated critical congenital heart defect (“CCHD”) screening systems and processes are described. A caregiver may be guided to use a single or dual sensor pulse oximeter to obtain pre- and post-ductal blood oxygenation measurements. A delta of the measurements indicates the possible existence or nonexistence of a CCHD. Errors in the measurements are reduced by a configurable measurement confidence threshold based on, for example, a perfusion index. Measurement data may be stored and retrieved from a remote data processing center for repeated screenings.

Abstract: Provided is a frequency transfer characteristic blood vessel index value calculation apparatus including a pulse wave acquisition unit that acquires first pulse wave data of a pulse wave at a first site, and second pulse wave data of a pulse wave at a second site; a pulse wave frequency characteristic derivation unit that derives a first frequency characteristic of the first pulse wave from the first pulse wave data and derives a second frequency characteristic of the second pulse wave from the second pulse wave data; a frequency transfer characteristic calculation unit that calculates a frequency transfer characteristic for a system that uses the first pulse wave as input and the second pulse wave as output; a frequency transfer characteristic correction unit that corrects the frequency transfer characteristic.

Abstract: Methods, systems, and non-transitory computer-readable recording media for monitoring blood pressure are provided. The method includes calculating an estimate of deviations between every two pulse transit time (PTT) values measured at an interval of a first period, and estimating a PTT value to be measured the first period after a current time. The method also includes calculating an estimate of deviations between every two oxygen saturation values measured at an interval of a second period, and estimating an oxygen saturation value to be measured the second period after the current time. The method additionally includes calculating current systolic blood pressure and diastolic blood pressure based on an electrocardiogram (ECG) value measured at the current time, the estimated PTT value, and the estimated oxygen saturation value.

Abstract: A method of estimating a blood pressure based on an image is provided. The method includes obtaining, by camera, an image including a skin of a user, determining, by a computer device, a skin region, in which at least one portion of the skin is displayed, from the image, and storing a mean value of color data of a designated color model for each of two target regions which have different positions in the skin region from each other, estimating, by the computer device, a pulse-wave transit time (PTT) based on a pulse wave signal determined based on a change in the mean value of the color data for each of the two target regions, and estimating, by the computer device, the blood pressure using the PTT.

Abstract: An apparatus and a method of measuring a biosignal are provided. The apparatus of measuring a biosignal includes an optical source configured to emit a first light and a second light towards a target, an inserted layer configured to transmit the first light and to reflect the second light, and an optical detector configured to detect a first received light that corresponds to the first light reflected by or transmitted through the target, and to detect a second received light that corresponds to the second light reflected by the inserted layer.

Abstract: Tools and techniques for the rapid, continuous, invasive and/or noninvasive measurement, estimation, and/or prediction of a patient's intracranial pressure. In an aspect, some tools and techniques can predict the onset of conditions such as herniation and/or can recommend (and, in some cases, administer) a therapeutic treatment for the patient's condition. In another aspect, some techniques employ high speed software technology that enables active, long term learning from extremely large, continually changing datasets. In some cases, this technology utilizes feature extraction, state-of-the-art machine learning and/or statistical methods to autonomously build and apply relevant models in real-time.

Abstract: A method of measuring and analyzing the ultra high frequency EKG is performed by measuring the EKG within the frequency range above 250 Hz with a dynamic range of at least 100 dB. In the UHF EKG signal positions of Rm of R wave in QRS complex of EKG are detected on the time axis and the EKG signal is converted to amplitude or power envelopes, the amplitude or power envelopes frequency range is anywhere within the limits from 0.2 Hz to at least 500 Hz. From these envelopes the amplitude and time numerical parameters that describe the myocardium depolarization inhomogeneity and electric myocardium dyssynchrony are determined, and these parameters are used for selecting the patients for multi-chamber stimulators implementation and optimization of their setting.

Abstract: This invention relates to at least one electrode for subdermal penetration to provide a substantially constant electrode impedance, said electrode associated with a power module and wireless module for receiving and transmitting physiological signals to a processing unit communicating with a server.

Abstract: The invention provides systems and methods for monitoring the wellbeing of a fetus by the non-invasive detection and analysis of fetal cardiac electrical activity data.

Abstract: A fetal state estimation apparatus estimates a state of a fetus in a maternal body based on a potential signal indicating a change in potential on a surface of the maternal body. The fetal state estimation apparatus is configured to include a rotation angle estimation unit which estimates a rotation angle of the fetus with respect to the maternal body at every beating of a heart of the fetus based on the potential signal and a fetal movement estimation unit which estimates a fetal movement which is a movement of the fetus based on the potential signal and the estimated rotation angle.

Abstract: The current subject matter determines the location of the J-point in an ECG signal by examining ECG samples within a window of samples between the S-peak and the T-peak. The sample in this range with the smallest distance, ?d, to the R-peak is selected as the J-point. Thus, the J-point location can be determined based on an ECG sample's distance to the R-peak. The J-point location can then be used to determine whether there is elevation or depression of the ST segment. Related apparatus, systems, techniques, and articles are also described.

Abstract: A system and methods for performing neurophysiology assessments during surgery, such as assessing the health of the spinal cord via at least one of MEP and SSEP monitoring and assessing bone integrity, nerve proximity, neuromuscular pathway, and nerve pathology during spine surgery.

Abstract: A sensor including an array of pins, a sensing element, a control module, and a physical layer module. The array of pins or needles is configured to be inserted in tissue of a patient. The sensing element is separate from the array of pins or needles and is configured to (i) detect a first parameter of the tissue, and (ii) generate a first signal indicative of the first parameter. The control module is configured to (i) receive the first signal, (ii) monitor a second parameter of the tissue based on a second signal received from the array of pins or needles, and (ii) generate a third signal based on the first signal and the second parameter, where the third signal is indicative of a level of decompression of a nerve of the patient. The physical layer module is configured to wirelessly transmit the third signal from the sensor to a console interface module or a nerve integrity monitoring device.

Abstract: Provided are a cognitive function evaluation apparatus, a cognitive function evaluation method and system, and a program that can be implemented for non-handicapped persons and persons with severe motor impairment. The apparatus according to the present invention is an apparatus for evaluating cognitive function provided with a processing unit that analyzes and processes a brain wave caused by a plurality of stimulus events including a target and a non-target; estimates a stimulus event selected as the target from the plurality of stimulus events; determines a discrimination score or decoding accuracy; and evaluates cognitive function on the basis of a value of one or more of the discrimination score, the decoding accuracy, any of time courses, and decoding speed.

Abstract: During operation, a system iteratively captures MR signals of one or more types of nuclei in one or more portions of a biological lifeform based on scanning instructions that correspond to a dynamic scan plan. The MR signals in a given iteration may be associated with voxels having associated sizes at three-dimensional (3D) positions in at least a corresponding portion of the biological lifeform. If the system detects a potential anomaly when analyzing the MR signals from the given iteration, the system dynamically modifies the scan plan based on the detected potential anomaly, a medical history and/or an MR-scan history. Subsequent measurements of MR signals may be associated with the same or different: types of nuclei, portions of the biological lifeform, voxels sizes and/or 3D positions.

Abstract: Microwave imaging device and method are provided, and the microwave imaging device includes a scan circuit, a reception circuit and an image generator. The scan circuit transmits a plurality of electromagnetic waves in a plurality of scan bands toward a target object. The scan bands are respectively corresponding to a plurality of biological tissues in the target object. The reception circuit receives the electromagnetic waves passing through the target object, and generates a plurality of energy values according to the received electromagnetic waves. The image generator looks up a plurality of gray level look-up tables by using the energy values to generate a plurality of gray level values, and generates a detection image corresponding to the biological tissues according to the gray level values.

Abstract: According to the exemplary embodiment of the present invention, a microwave tomography apparatus is an apparatus which measures microwave tomograph of a subject which is inserted into a medium container including: a plurality of antennas which is located in the medium container and transmits and receives an electromagnetic wave; a plurality of transceivers which, when a radio wave signal transmitted from one of the plurality of antennas is simultaneously received by the remaining antennas of the plurality of antennas, measures intensity and phase information of the radio wave signal received from the remaining antennas; and a controller which generates an image using the values measured by the plurality of transceivers.

Abstract: Electrical impedance myography (EIM) can be used for assessment and diagnosis of muscular disorders. EIM includes applying an electrical signal to a region of tissue and measuring a resulting signal. A characteristic of the region of tissue is determined based on the measurement. Performing EIM at different frequencies and modeling one or more impedance metrics as a function of frequency may provide impedance model parameters that can aid in the assessment and diagnosis. Devices are described that facilitate assessment and diagnosis using EIM.

Abstract: A method for use in analysing impedance measurements performed on a subject, the method including, in a processing system determining at least one impedance value, representing the impedance of at least a segment of the subject, determining an indicator indicative of a subject parameter using the at least one impedance value and a reference and displaying a representation of the indicator.

Abstract: The present disclosure provides apparatuses and computer readable media for measuring sub-epidermal moisture in patients to determine damaged tissue for clinical intervention. The present disclosure also provides methods for determining damaged tissue.

Abstract: A device and method for mapping, diagnosing and treating inflammatory disorders (such as Crohn's disease) or other diseases, disorders or conditions of the intestinal tract is provided using a capsule passing through the intestinal tract. Further, a capsule tracking system is provided for tracking a capsule's location along the length of an intestinal tract as various treatment and/or sensing modalities are employed. In one variation, an acoustic signal is used to determine the location of the capsule. A map of sensed impedance and or temperature may be derived from the pass of a capsule to diagnose the disorder or disease. The capsule or subsequently passed capsules may treat, further diagnose, or mark the intestinal tract at a determined location along its length.

Abstract: A location pad includes multiple field-generators and a frame. The field-generators are configured to generate respective magnetic fields in a region-of-interest of a patient body, for measuring a position of a medical instrument in the region-of-interest. The frame is configured to fix the multiple field-generators at respective positions surrounding the region-of-interest. The frame is open on at least one side of the region-of-interest.

Abstract: A field generator includes multiple planar coils that are arranged in a single plane. At least two of the coils are non-concentric and are wound around respective axes that are not parallel with one another, so as to generate respective magnetic fields that are not parallel with one another.

Abstract: A method includes disposing a pair of current-application electrodes in or on a body, including disposing an intrarenal current-application electrode of the pair in a renal artery. Two or more sensing electrodes are disposed in or on the body, including disposing one of the sensing electrodes on en external surface of skin. Control circuitry is activated to (a) apply an electrical current between the pair of current-application electrodes, (b) while applying the electrical current, sense an electrical signal between the sensing electrodes, including the sensing electrode disposed on the external surface of the skin, and (c) based on the electrical signal, ascertain a level of contact between the intrarenal current-application electrode and a wall of the renal artery. In response to the level of contact being less than a threshold level of contact, a disposition of the intrarenal current-application electrode in the renal artery is adjusted.